AutismKB 2.0

Annotation Detail for PPP5C


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Basic Information Top
Gene Symbol:PPP5C ( FLJ36922,PP5,PPP5 )
Gene Full Name: protein phosphatase 5, catalytic subunit
Band: 19q13.32
Quick LinksEntrez ID:5536; OMIM: 600658; Uniprot ID:PPP5_HUMAN; ENSEMBL ID: ENSG00000011485; HGNC ID: 9322
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
No data
Pathway IDPathway Name
hsa04010MAPK signaling pathway
No data
Pathway IDPathway Name
200077Glucocorticoid receptor regulatory network
200113ErbB1 downstream signaling
No data
No data
Related Diseases/Disorders Top
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C016403 2,4-dinitrotoluene 2,4-dinitrotoluene affects the expression of PPP5C mRNAaffects expression 21346803
C009505 4,4'-diaminodiphenylmethane 4,4'-diaminodiphenylmethane results in increased expression of PPP5C mRNAincreases expression 18648102
D000643 Ammonium Chloride Ammonium Chloride affects the expression of PPP5C mRNAaffects expression 16483693
D003024 Clozapine Clozapine affects the expression of PPP5C mRNAaffects expression 14647396
D016572 Cyclosporine Cyclosporine results in decreased expression of PPP5C mRNAdecreases expression 20106945
D004997 Ethinyl Estradiol Ethinyl Estradiol results in increased expression of PPP5C mRNAincreases expression 17942748
D004997 Ethinyl Estradiol [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of PPP5C mRNAaffects cotreatment|increases expression 17942748
D006220 Haloperidol Haloperidol results in decreased expression of PPP5C mRNAdecreases expression 14647396
D019319 Okadaic Acid Okadaic Acid binds to and results in decreased activity of PPP5C proteinaffects binding|decreases activity 15767308
D016559 Tacrolimus Tacrolimus promotes the reaction [NR3C1 protein binds to PPP5C protein]affects binding|increases reaction 15697228
D013629 Tamoxifen Tamoxifen results in decreased expression of PPP5C mRNAdecreases expression 17555576
D013749 Tetrachlorodibenzodioxin [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of PPP5C mRNAaffects cotreatment|increases expression 17942748
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in increased expression of PPP5C mRNAincreases expression 17942748
C052342 topiramate topiramate results in increased expression of PPP5C mRNAincreases expression 16979414
D014212 Tretinoin Tretinoin results in increased expression of PPP5C mRNAincreases expression 16054129
C025643 vinclozolin vinclozolin affects the expression of PPP5C mRNAaffects expression 19015723
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000008 Abdominal Neoplasms Tamoxifen 4.6414745880
MESH:D000014 Abnormalities, Drug-Induced Tetrachlorodibenzodioxin 2.9311752688 15322242 14514962
MESH:D000138 Acidosis Ammonium Chloride 3.6418287403
MESH:D000152 Acne Vulgaris Ethinyl Estradiol 4.0417505938
MESH:D000230 Adenocarcinoma Ethinyl Estradiol 1.8214692618
MESH:D000236 Adenoma 4,4'-diaminodiphenylmethane 2.783712494
MESH:D018248 Adenoma, Liver Cell Tetrachlorodibenzodioxin 3.4616835633
MESH:D000380 Agranulocytosis Clozapine 5.1316160616 14617031 12649775
MESH:D000437 Alcoholism topiramate 5.0719331489 17925516 18552399
MESH:D000505 Alopecia Tretinoin 3.6615955085
MESH:D000740 Anemia Tetrachlorodibenzodioxin 3.0011748828
MESH:D001008 Anxiety Disorders vinclozolin 3.6819015723
MESH:D001161 Arteriosclerosis Ethinyl Estradiol 3.5411256880
MESH:D001169 Arthritis, Experimental Ethinyl Estradiol 7.3115885639
MESH:D001169 Arthritis, Experimental Tretinoin 7.3116412693
MESH:D001172 Arthritis, Rheumatoid Tretinoin 2.2716292516
MESH:D001249 Asthma Tretinoin 2.3616456186
MESH:D001321 Autistic Disorder Haloperidol 2.7319368416 18080171
MESH:D001471 Barrett Esophagus Tretinoin 4.4716935849
MESH:D001660 Biliary Tract Diseases 4,4'-diaminodiphenylmethane 5.1211289319 1440618
MESH:D001778 Blood Coagulation Disorders Tetrachlorodibenzodioxin 9.1212125929
MESH:D001778 Blood Coagulation Disorders Tretinoin 9.1216206674 16197459
MESH:D001836 Body Weight Changes Tetrachlorodibenzodioxin 3.8915340226
MESH:D001848 Bone Diseases, Developmental Tetrachlorodibenzodioxin 2.8015746008
MESH:D001943 Breast Neoplasms Tamoxifen 1.8319142967 18629630 19410462 20544844 19289846 19288272 16273361 19189212 21152245 18815881 20859285 19011961 18351453 17049068 19200415 17893378 21138602 19487384 18855134 15565566 19059307 19155303 16873071 20135344 17440819 19221464 18425577 15668708 20005174 20390343 16202921 19084267 19066611 17261762 16818667 11161223 19244106 19115204 18821012 19189210 18997820 18984771 19103187 17242785 20065188
MESH:D001943 Breast Neoplasms Tetrachlorodibenzodioxin 1.8320435547
MESH:D001943 Breast Neoplasms Tretinoin 1.8316166294 16443354 16873071
MESH:D001997 Bronchopulmonary Dysplasia Tretinoin 4.6716813970
MESH:D002277 Carcinoma Tetrachlorodibenzodioxin 2.8416835633
MESH:D018270 Carcinoma, Ductal, Breast Tamoxifen 4.5819066611
MESH:D018236 Carcinoma, Embryonal Tretinoin 5.2616168501
MESH:D006528 Carcinoma, Hepatocellular 2,4-dinitrotoluene 6.6416705839
MESH:D006528 Carcinoma, Hepatocellular 4,4'-diaminodiphenylmethane 6.647296757 3581430
MESH:D006528 Carcinoma, Hepatocellular Tamoxifen 6.6416924424
MESH:D006528 Carcinoma, Hepatocellular Tretinoin 6.641917145
MESH:D002292 Carcinoma, Renal Cell 4,4'-diaminodiphenylmethane 2.707296757
MESH:D002294 Carcinoma, Squamous Cell Tretinoin 2.3016051514 16096774
MESH:D002295 Carcinoma, Transitional Cell Tamoxifen 3.6617572228
MESH:D006332 Cardiomegaly Tetrachlorodibenzodioxin 2.3918850075 18670907 16120746
MESH:D002318 Cardiovascular Diseases Tacrolimus 4.6517703430
MESH:D002375 Catalepsy Haloperidol 4.9915215559 1977408
MESH:D002386 Cataract Tretinoin 3.1217460283
MESH:D002471 Cell Transformation, Neoplastic 4,4'-diaminodiphenylmethane 6.697505956
MESH:D002471 Cell Transformation, Neoplastic Cyclosporine 6.6912371664
MESH:D018290 Cervical Intraepithelial Neoplasia Tretinoin 4.6716129372
MESH:D002659 Child Development Disorders, Pervasive topiramate 4.1115650499
MESH:D018281 Cholangiocarcinoma Tetrachlorodibenzodioxin 3.2116835633
MESH:D002779 Cholestasis 4,4'-diaminodiphenylmethane 13.6219486331 9022650
MESH:D002779 Cholestasis Cyclosporine 13.6219486331
MESH:D002779 Cholestasis Ethinyl Estradiol 13.6216105132 15861022 16919318 17333356 11677210 17110522 17681005
MESH:D002822 Choriocarcinoma Tretinoin 5.2616461808
MESH:D002972 Cleft Palate Tetrachlorodibenzodioxin 5.8312621046 8697196 15340226 16354765 15668235
MESH:D002972 Cleft Palate Tretinoin 5.839407595
MESH:D003072 Cognition Disorders Clozapine 5.0417123785
MESH:D003092 Colitis Tretinoin 3.7817035595
MESH:D000013 Congenital Abnormalities Tetrachlorodibenzodioxin 3.1114669216 17141729
MESH:D019465 Craniofacial Abnormalities Tetrachlorodibenzodioxin 2.4615322242 20055451 10048152
MESH:D019465 Craniofacial Abnormalities Tretinoin 2.4617551590 14991402 10589399 9125849 9224671 9664655 16925845 8800419 9211117 9142499
MESH:D003456 Cryptorchidism vinclozolin 4.4114966744
MESH:D003490 Cyanosis 2,4-dinitrotoluene 4.0918551238
MESH:D016757 Death, Sudden, Cardiac Haloperidol 4.9020210726
MESH:D003704 Dementia Haloperidol 4.6311575062
MESH:D003711 Demyelinating Diseases Tamoxifen 4.4319031437
MESH:D017449 Dermatitis, Allergic Contact 4,4'-diaminodiphenylmethane 2.8718759878 14531868 8970840 11906362 12868966 8156756 2524372 11298694
MESH:D003877 Dermatitis, Contact 4,4'-diaminodiphenylmethane 3.553621924 2952479
MESH:D003924 Diabetes Mellitus, Type 2 Clozapine 7.4516402076
MESH:D003924 Diabetes Mellitus, Type 2 Tetrachlorodibenzodioxin 7.4517107852
MESH:D003924 Diabetes Mellitus, Type 2 topiramate 7.4516979414
MESH:D003928 Diabetic Nephropathies Tamoxifen 3.5219279558
MESH:D006970 Disorders of Excessive Somnolence Clozapine 5.6515331141
MESH:D056486 Drug-Induced Liver Injury 2,4-dinitrotoluene 6.2518551238 21346803
MESH:D056486 Drug-Induced Liver Injury 4,4'-diaminodiphenylmethane 6.256482804 7440962 18289764 6679447 18648102 16192314 18692083 8291058 11289319 9653073 9328219 1440618 9022650
MESH:D056486 Drug-Induced Liver Injury Tetrachlorodibenzodioxin 6.2520420201
MESH:D004362 Drug Toxicity Tetrachlorodibenzodioxin 2.8011462148
MESH:D004381 Duodenal Ulcer Tacrolimus 5.2017202747
MESH:D050171 Dyslipidemias Clozapine 4.2216402076
MESH:D004487 Edema Tetrachlorodibenzodioxin 2.4312711302 11000095
MESH:D004489 Edema, Cardiac Tetrachlorodibenzodioxin 12.2715322242 16714409 18230668
MESH:D004489 Edema, Cardiac Tretinoin 12.2718230668
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Ethinyl Estradiol 9.1612538720
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Tamoxifen 9.1619031437
MESH:D016889 Endometrial Neoplasms Tamoxifen 7.5516202921 20544844 19155303 17893378
MESH:D016889 Endometrial Neoplasms Tretinoin 7.5516569247
MESH:D004715 Endometriosis Tetrachlorodibenzodioxin 3.0710568697 9294722
MESH:D004827 Epilepsy topiramate 4.3519148780
MESH:D004833 Epilepsy, Temporal Lobe topiramate 6.3716499746
MESH:D004938 Esophageal Neoplasms 4,4'-diaminodiphenylmethane 2.123581430
MESH:D005124 Eye Abnormalities Tetrachlorodibenzodioxin 8.9711564622
MESH:D005124 Eye Abnormalities Tretinoin 8.9716938888 9664655
MESH:D005234 Fatty Liver Cyclosporine 13.3819224547
MESH:D005234 Fatty Liver Ethinyl Estradiol 13.3815345470
MESH:D005234 Fatty Liver Tamoxifen 13.3814986274 19224547
MESH:D052776 Female Urogenital Diseases Tamoxifen 3.2716709447
MESH:D005313 Fetal Death Tetrachlorodibenzodioxin 3.5311858732
MESH:D005350 Fibroma 4,4'-diaminodiphenylmethane 5.126705139
MESH:D018221 Fibromatosis, Abdominal Tamoxifen 4.6114745880
MESH:D018222 Fibromatosis, Aggressive Tamoxifen 4.2619069698
MESH:D005355 Fibrosis Cyclosporine 15.1612639820 12168785
MESH:D005355 Fibrosis Tetrachlorodibenzodioxin 15.1620067830
MESH:D005355 Fibrosis Tretinoin 15.1617994277
MESH:D030342 Genetic Diseases, Inborn vinclozolin 5.0216973722
MESH:D005832 Genital Diseases, Male vinclozolin 5.4016417039
MESH:D005885 Gingival Hyperplasia Cyclosporine 4.308708960
MESH:D005909 Glioblastoma Okadaic Acid 7.8317312396
MESH:D005909 Glioblastoma Tretinoin 7.8317312396
MESH:D006042 Goiter 4,4'-diaminodiphenylmethane 4.107505956
MESH:D006058 Gonadal Disorders Tetrachlorodibenzodioxin 4.6910696789
MESH:D006086 Graft vs Host Disease Tacrolimus 5.9516376943
MESH:D006130 Growth Disorders Tacrolimus 4.9511041285
MESH:D006258 Head and Neck Neoplasms Tretinoin 3.2216096774
MESH:D006317 Hearing Loss, Noise-Induced Tretinoin 5.2616084493
MESH:D006330 Heart Defects, Congenital Tetrachlorodibenzodioxin 6.6210048152 11294989
MESH:D006330 Heart Defects, Congenital Tretinoin 6.629664655 14991402
MESH:D006457 Hemoglobinuria, Paroxysmal Cyclosporine 4.5015720958
MESH:D006470 Hemorrhage Tetrachlorodibenzodioxin 3.3911000095
MESH:D006505 Hepatitis 4,4'-diaminodiphenylmethane 3.586705139
MESH:D006529 Hepatomegaly Tetrachlorodibenzodioxin 2.9616120746 12621046 15340226
MESH:D006869 Hydronephrosis Tetrachlorodibenzodioxin 4.148697196 18606429 16354765 15340226 16959395
MESH:D006930 Hyperalgesia Tretinoin 3.2516870215
MESH:D017681 Hypereosinophilic Syndrome Tretinoin 4.6416778211
MESH:D006948 Hyperkinesis Clozapine 4.9916046005
MESH:D006965 Hyperplasia 4,4'-diaminodiphenylmethane 4.0115034207
MESH:D006973 Hypertension Cyclosporine 5.0110903974
MESH:D006973 Hypertension Tetrachlorodibenzodioxin 5.0118670907 18850075
MESH:C537153 Hypomagnesemia primary Tacrolimus 6.2411041285
MESH:D007021 Hypospadias Ethinyl Estradiol 3.8816569931 16945680
MESH:D007022 Hypotension Tacrolimus 5.1811041285
MESH:D007247 Infertility, Female Ethinyl Estradiol 3.5212013081
MESH:D007248 Infertility, Male Ethinyl Estradiol 6.7817937319
MESH:D007248 Infertility, Male vinclozolin 6.7816467254
MESH:D007249 Inflammation Tamoxifen 4.9819457130
MESH:D007249 Inflammation Tetrachlorodibenzodioxin 4.9812200463 12878042
MESH:D007410 Intestinal Diseases Tretinoin 3.8417994277
MESH:D007565 Jaundice 4,4'-diaminodiphenylmethane 5.129022650 8074119
MESH:D007569 Jaw Abnormalities Tetrachlorodibenzodioxin 10.1216580747
MESH:D007569 Jaw Abnormalities Tretinoin 10.1217551590 15992940
MESH:D007638 Keratoconjunctivitis Sicca Cyclosporine 4.5415604871
MESH:D007674 Kidney Diseases Cyclosporine 6.6618776723 10903974 8314463
MESH:D007674 Kidney Diseases Tacrolimus 6.6611041285
MESH:D007680 Kidney Neoplasms 2,4-dinitrotoluene 18.1316705839
MESH:D007680 Kidney Neoplasms 4,4'-diaminodiphenylmethane 18.136582329
MESH:D007680 Kidney Neoplasms Cyclosporine 18.1312371664
MESH:D007680 Kidney Neoplasms Tamoxifen 18.1318625569
MESH:D007938 Leukemia Tretinoin 2.7917143497
MESH:D007951 Leukemia, Myeloid Tretinoin 3.7516482212 19285840 16932348
MESH:D015470 Leukemia, Myeloid, Acute Tretinoin 2.0817596541 19850784 16294345
MESH:D015473 Leukemia, Promyelocytic, Acute Tretinoin 3.1917339181 17294898 17107899 16788101 19035177 16823087 17368321 12679006 19642359 19075265 16140955 17506722 17301526 17649720 16331271 19029980 17217047 17712046 15748426 9834237 16935935 17361223 16766008 16891316 19225113
MESH:D007984 Leydig Cell Tumor vinclozolin 4.8116417039
MESH:D017880 Limb Deformities, Congenital Tretinoin 3.349224671
MESH:D008064 Lipidoses Clozapine 8.2117567588
MESH:D008064 Lipidoses Tamoxifen 8.2115342952 17567588
MESH:D008105 Liver Cirrhosis, Biliary 4,4'-diaminodiphenylmethane 3.2315034207 9327722
MESH:D008106 Liver Cirrhosis, Experimental Tamoxifen 3.4818564211
MESH:D008106 Liver Cirrhosis, Experimental Tetrachlorodibenzodioxin 3.4812878042
MESH:D008106 Liver Cirrhosis, Experimental Tretinoin 3.4818397230 16248980
MESH:D008113 Liver Neoplasms Tamoxifen 4.4616684651
MESH:D008113 Liver Neoplasms Tetrachlorodibenzodioxin 4.4616984957
MESH:D008114 Liver Neoplasms, Experimental 4,4'-diaminodiphenylmethane 5.84598648 6587162 1399818 3712494
MESH:D008114 Liver Neoplasms, Experimental Tetrachlorodibenzodioxin 5.8412151625
MESH:D008175 Lung Neoplasms Tamoxifen 2.2618625569
MESH:D008175 Lung Neoplasms Tetrachlorodibenzodioxin 2.2619555203 11884234
MESH:D015674 Mammary Neoplasms, Animal Tamoxifen 3.8419428831
MESH:D008325 Mammary Neoplasms, Experimental Tamoxifen 2.6611731420 19196722 14580682 16827153 19196723
MESH:D020149 Manganese Poisoning Tamoxifen 4.6419453300
MESH:D008527 Medulloblastoma Tretinoin 2.8017453147
MESH:D008545 Melanoma Tamoxifen 3.3112393984 19393235
MESH:D008545 Melanoma Tretinoin 3.3116752155
MESH:D018328 Melanoma, Amelanotic Tamoxifen 4.2615990972
MESH:D008591 Meningomyelocele Tretinoin 4.5016940565
MESH:D001523 Mental Disorders Clozapine 8.6416856516
MESH:D001523 Mental Disorders Haloperidol 8.6416856516
MESH:D024821 Metabolic Syndrome X Clozapine 4.4619142101
MESH:D008664 Metal Metabolism, Inborn Errors Cyclosporine 4.8816801185
MESH:D008881 Migraine Disorders topiramate 4.6118803445 18765137 16942474 18759728
MESH:D009190 Myelodysplastic Syndromes Tretinoin 3.1117596541
MESH:D017202 Myocardial Ischemia Tetrachlorodibenzodioxin 3.0612213967
MESH:D009336 Necrosis 2,4-dinitrotoluene 3.9418551238
MESH:D009362 Neoplasm Metastasis 4,4'-diaminodiphenylmethane 5.763581430
MESH:D009362 Neoplasm Metastasis Tamoxifen 5.7619393235
MESH:D009364 Neoplasm Recurrence, Local Tamoxifen 2.5319410462
MESH:D009369 Neoplasms Tretinoin 2.4316946489 16594593
MESH:D009376 Neoplasms, Hormone-Dependent Tamoxifen 4.1019196722 19189210 19200415
MESH:D009402 Nephrosis, Lipoid Cyclosporine 4.5417954296
MESH:D009404 Nephrotic Syndrome Cyclosporine 3.3318481113 19348381
MESH:D009421 Nervous System Malformations Tetrachlorodibenzodioxin 9.7314600291
MESH:D009421 Nervous System Malformations Tretinoin 9.739125849
MESH:D009436 Neural Tube Defects 4,4'-diaminodiphenylmethane 7.346679447
MESH:D009436 Neural Tube Defects Tretinoin 7.349142499
MESH:D019636 Neurodegenerative Diseases Tacrolimus 4.9915081597
MESH:D009765 Obesity Clozapine 3.0318515891 19142110
MESH:D009784 Occupational Diseases 2,4-dinitrotoluene 9.0512819281 16049721
MESH:D009784 Occupational Diseases 4,4'-diaminodiphenylmethane 9.056482804 4026338
MESH:D009902 Optic Neuritis 4,4'-diaminodiphenylmethane 5.123988306
MESH:D010051 Ovarian Neoplasms Tretinoin 2.3616936753
MESH:D010146 Pain Tretinoin 2.9516870215
MESH:D010190 Pancreatic Neoplasms Tretinoin 2.4815976015
MESH:D016584 Panic Disorder Ethinyl Estradiol 3.7511578682
MESH:D010212 Papilloma 4,4'-diaminodiphenylmethane 3.557296757
MESH:D010382 Peliosis Hepatis Tetrachlorodibenzodioxin 4.3512520081
MESH:D010787 Photosensitivity Disorders 4,4'-diaminodiphenylmethane 4.576228378
MESH:D017119 Porphyria Cutanea Tarda Tetrachlorodibenzodioxin 3.6218163543
MESH:D011230 Precancerous Conditions Cyclosporine 3.2712371664
MESH:D011297 Prenatal Exposure Delayed Effects Tetrachlorodibenzodioxin 9.7711399792 11896295 11222880 11118676
MESH:D011297 Prenatal Exposure Delayed Effects vinclozolin 9.7719015723 18220299 18042343
MESH:D011469 Prostatic Diseases vinclozolin 5.0218220299
MESH:D011471 Prostatic Neoplasms Tamoxifen 3.1415067354
MESH:D011472 Prostatitis vinclozolin 5.0218629315
MESH:D011507 Proteinuria Tretinoin 3.6616636307
MESH:D011537 Pruritus Ethinyl Estradiol 3.3915861022 16919318
MESH:D011565 Psoriasis Cyclosporine 2.2416882103
MESH:D011595 Psychomotor Agitation Haloperidol 5.0311575062
MESH:D011618 Psychotic Disorders Clozapine 9.2915331141
MESH:D011618 Psychotic Disorders Haloperidol 9.2911575062
MESH:D011625 Pterygium Tretinoin 4.8816723453
MESH:D015619 Respiratory System Abnormalities Tetrachlorodibenzodioxin 3.9018990726
MESH:D012162 Retinal Degeneration 4,4'-diaminodiphenylmethane 3.413692021
MESH:D012208 Rhabdomyosarcoma Tretinoin 4.1616116481 16283617
MESH:D012559 Schizophrenia Clozapine 4.1211763009 18806925 17726453 17667964 20107430 19369910 18855531 20521320 20580759 20452607 16141801 17123785 20521326 20168265 11151749
MESH:D012559 Schizophrenia Haloperidol 4.121830565 19369910 20107430 18513383
MESH:D012640 Seizures 2,4-dinitrotoluene 6.5718551238
MESH:D012640 Seizures topiramate 6.5716499746
MESH:D012878 Skin Neoplasms Okadaic Acid 9.7812628509
MESH:D012878 Skin Neoplasms Tetrachlorodibenzodioxin 9.7816192470
MESH:D012878 Skin Neoplasms Tretinoin 9.7816467112
MESH:D013088 Spermatocele Ethinyl Estradiol 11.8916709447
MESH:D013088 Spermatocele Tamoxifen 11.8916709447
MESH:D013119 Spinal Cord Injuries Tamoxifen 4.1219457130
MESH:D013274 Stomach Neoplasms Tretinoin 1.8017261132
MESH:D017180 Tachycardia, Ventricular Haloperidol 4.7720210726
MESH:D019851 Thrombophilia Ethinyl Estradiol 3.6811994571
MESH:D013927 Thrombosis Ethinyl Estradiol 3.2015669648
MESH:D013959 Thyroid Diseases Tetrachlorodibenzodioxin 4.0012697716
MESH:D013964 Thyroid Neoplasms 4,4'-diaminodiphenylmethane 7.276587162 3712494 7505956 6582329 1399818
MESH:D013964 Thyroid Neoplasms Tretinoin 7.2717045167 16026305
MESH:D014062 Tongue Neoplasms Tretinoin 3.8416051514
MESH:D014376 Tuberculosis Tretinoin 3.2616040207
MESH:D001749 Urinary Bladder Neoplasms 2,4-dinitrotoluene 8.4016049721
MESH:D001749 Urinary Bladder Neoplasms 4,4'-diaminodiphenylmethane 8.408074119
MESH:D001749 Urinary Bladder Neoplasms Tamoxifen 8.408653321 16712894 17572228
MESH:D014571 Urologic Neoplasms 2,4-dinitrotoluene 4.4010091137
MESH:D002583 Uterine Cervical Neoplasms Tretinoin 3.7316129372
MESH:D014594 Uterine Neoplasms Ethinyl Estradiol 3.3614692618
MESH:D014604 Uveal Neoplasms Tretinoin 4.7116752155
MESH:D014605 Uveitis Cyclosporine 4.081336536
MESH:D054079 Vascular Malformations Tetrachlorodibenzodioxin 4.6912125929
MESH:D020246 Venous Thrombosis Ethinyl Estradiol 3.5915869587 14671159
MESH:D014820 Vitiligo Tretinoin 4.1216761959
MESH:D019282 Wasting Syndrome Tetrachlorodibenzodioxin 4.3515886252
MESH:D015430 Weight Gain Clozapine 4.5220564506 20107430 16402076 16141801 17502770 20521320
MESH:D015431 Weight Loss Clozapine 5.1617933447
MESH:D009396 Wilms Tumor Tretinoin 4.0216287080
MESH:D014985 Xerophthalmia Cyclosporine 4.5417120751
Pathway ID Pathway Name
KEGG:04010 MAPK signaling pathway
Pharmacogenomics Knowledge Base Top
  • PharmGKB Accession:PA33686
    • No data
    No data
    Releated drug ID Related drug Name
    PA451365sirolimus
    Drug Bank Top
    Drugbank ID Action Drug Name Description
    DB03684 - 2-Methyl-2,4-Pentanediol
    No data
    No data
    No data

    Simple Query:


      (e.g. CHD8)

    Syndromic Genes

    Non-syndromic Genes

    AutismKB Statistics

    • Studies: 1,036
    • Genes: 1,379
    • CNVs/SVs: 5,420
    • SNVs/Indels: 11,669
    • de novo Mutations: 5,669
    • Mosaics: 789
    • Linkage Regions: 172
    • Paper Collected: 6/30/2018
    • Last Update: 8/26/2018


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