Annotation Detail for CHST12
Basic Information Top
| Gene Symbol: | CHST12 ( C4S-2,C4ST-2,C4ST2 ) |
|---|---|
| Gene Full Name: | carbohydrate (chondroitin 4) sulfotransferase 12 |
| Band: | 7p22.3 |
| Quick Links | Entrez ID:55501; OMIM: 610129; Uniprot ID:CHSTC_HUMAN; ENSEMBL ID: ENSG00000136213; HGNC ID: 17423 |
| Relate to Another Database: | SFARIGene; denovo-db |
Related Diseases/Disorders| Chemical ID | Chemical Name | Interaction | Interaction Action | Publication |
|---|---|---|---|---|
| D000082 | Acetaminophen | Acetaminophen affects the expression of CHST12 mRNA | affects expression | 17562736 |
| D004041 | Dietary Fats | Dietary Fats results in decreased expression of CHST12 mRNA | decreases expression | 18042831 |
| D004997 | Ethinyl Estradiol | Ethinyl Estradiol results in increased expression of CHST12 mRNA | increases expression | 17942748 |
| C041786 | palm oil | palm oil results in decreased expression of CHST12 mRNA | decreases expression | 18042831 |
| Disease ID | Disease Name | Direct Evidence | Inference Chemical Name | Inference Score | Publication |
|---|---|---|---|---|---|
| MESH:D000152 | Acne Vulgaris | Ethinyl Estradiol | 4.66 | 17505938 | |
| MESH:D000230 | Adenocarcinoma | Ethinyl Estradiol | 1.88 | 14692618 | |
| MESH:D000799 | Angioedema | Acetaminophen | 4.57 | 10982225 | |
| MESH:D001161 | Arteriosclerosis | Dietary Fats | 11.85 | 15238619 | |
| MESH:D001161 | Arteriosclerosis | Ethinyl Estradiol | 11.85 | 11256880 | |
| MESH:D001169 | Arthritis, Experimental | Ethinyl Estradiol | 2.89 | 15885639 | |
| MESH:D001321 | Autistic Disorder | Acetaminophen | 1.40 | 18445737 | |
| MESH:D001943 | Breast Neoplasms | Dietary Fats | 2.24 | 20435547 | |
| MESH:D006528 | Carcinoma, Hepatocellular | Acetaminophen | 1.41 | 3084413 | |
| MESH:D002386 | Cataract | Acetaminophen | 2.79 | 10977129 | |
| MESH:D002779 | Cholestasis | Ethinyl Estradiol | 3.17 | 11677210 16105132 17333356 16919318 17110522 17681005 15861022 | |
| MESH:D056486 | Drug-Induced Liver Injury | Acetaminophen | 1.67 | 17906064 16227642 16109766 14986274 11739529 10774834 11461765 11834606 19085960 17522070 16781746 12958197 11743745 15619225 12705907 19420014 19416960 11421492 18071297 16485898 16081117 19370779 19739265 17562736 16177239 10663392 14725611 16393943 11287661 19923254 15968718 11529661 10915739 2444490 18713872 12392966 12540782 19164858 12594235 12153990 14550746 | |
| MESH:D056487 | Drug-Induced Liver Injury, Chronic | Acetaminophen | 4.82 | 19426721 | |
| MESH:D050171 | Dyslipidemias | Dietary Fats | 3.73 | 18367378 | |
| MESH:D004681 | Encephalomyelitis, Autoimmune, Experimental | Ethinyl Estradiol | 3.69 | 12538720 | |
| MESH:D005234 | Fatty Liver | Dietary Fats | 9.16 | 17967931 19004024 19551842 18296743 | |
| MESH:D005234 | Fatty Liver | Ethinyl Estradiol | 9.16 | 15345470 | |
| MESH:D005355 | Fibrosis | Dietary Fats | 4.08 | 18296743 | |
| MESH:D005756 | Gastritis | Acetaminophen | 4.40 | 16983495 | |
| MESH:D006930 | Hyperalgesia | Acetaminophen | 3.02 | 16870215 | |
| MESH:D006937 | Hypercholesterolemia | Dietary Fats | 4.02 | 21332399 | |
| MESH:D006949 | Hyperlipidemias | Dietary Fats | 4.08 | 21332399 | |
| MESH:D007021 | Hypospadias | Ethinyl Estradiol | 4.37 | 16569931 16945680 | |
| MESH:D007247 | Infertility, Female | Ethinyl Estradiol | 3.92 | 12013081 | |
| MESH:D007248 | Infertility, Male | Ethinyl Estradiol | 2.73 | 17937319 | |
| MESH:D007249 | Inflammation | Dietary Fats | 2.60 | 20412841 | |
| MESH:D007333 | Insulin Resistance | Dietary Fats | 3.34 | 18457598 11836018 | |
| MESH:D007674 | Kidney Diseases | Acetaminophen | 2.40 | 12587719 15629191 | |
| MESH:D008103 | Liver Cirrhosis | Dietary Fats | 3.07 | 18296743 | |
| MESH:D008107 | Liver Diseases | Acetaminophen | 1.70 | 16611625 19014921 12969438 16610002 19784758 12587719 19460945 11587558 | |
| MESH:D017114 | Liver Failure, Acute | Acetaminophen | 3.63 | 16871587 17185352 | |
| MESH:D008546 | Melanoma, Experimental | Acetaminophen | 4.13 | 19513568 | |
| MESH:D019636 | Neurodegenerative Diseases | Acetaminophen | 3.21 | 18514411 | |
| MESH:D009765 | Obesity | Dietary Fats | 2.36 | 19632207 21332399 18674790 16723640 20132043 11836018 17217161 20518802 18457598 | |
| MESH:D010146 | Pain | Acetaminophen | 2.73 | 16870215 | |
| MESH:D016584 | Panic Disorder | Ethinyl Estradiol | 4.15 | 11578682 | |
| MESH:D011537 | Pruritus | Ethinyl Estradiol | 3.94 | 16919318 15861022 | |
| MESH:D013088 | Spermatocele | Ethinyl Estradiol | 4.66 | 16709447 | |
| MESH:D019851 | Thrombophilia | Ethinyl Estradiol | 4.08 | 11994571 | |
| MESH:D013927 | Thrombosis | Ethinyl Estradiol | 3.52 | 15669648 | |
| MESH:D014581 | Urticaria | Acetaminophen | 3.44 | 10982225 | |
| MESH:D014594 | Uterine Neoplasms | Ethinyl Estradiol | 3.80 | 14692618 | |
| MESH:D020246 | Venous Thrombosis | Ethinyl Estradiol | 3.97 | 15869587 14671159 | |
| MESH:D015430 | Weight Gain | Dietary Fats | 4.11 | 16723640 |
| Pathway ID | Pathway Name |
|---|---|
| KEGG:00532 | Glycosaminoglycan biosynthesis - chondroitin sulfate |
| KEGG:00920 | Sulfur metabolism |