AutismKB 2.0

Annotation Detail for SRGN


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Basic Information Top
Gene Symbol:SRGN ( FLJ12930,MGC9289,PPG,PRG,PRG1 )
Gene Full Name: serglycin
Band: 10q22.1
Quick LinksEntrez ID:5552; OMIM: 177040; Uniprot ID:SRGN_HUMAN; ENSEMBL ID: ENSG00000122862; HGNC ID: 9361
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
Related Diseases/Disorders Top
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
D000082 Acetaminophen Acetaminophen affects the expression of SRGN mRNAaffects expression 17562736
D016604 Aflatoxin B1 Aflatoxin B1 affects the expression of SRGN proteinaffects expression 20106945
D000643 Ammonium Chloride Ammonium Chloride affects the expression of SRGN mRNAaffects expression 16483693
D001554 Benzene Benzene results in decreased expression of SRGN mRNAdecreases expression 15120971
D020122 tert-Butylhydroperoxide tert-Butylhydroperoxide results in increased expression of SRGN mRNAincreases expression 15336504
D016572 Cyclosporine Cyclosporine results in increased expression of SRGN mRNAincreases expression 20106945
D003561 Cytarabine Cytarabine results in increased expression of SRGN mRNAincreases expression 19194470
C014347 decitabine decitabine results in increased expression of SRGN mRNAincreases expression 19194470
D003907 Dexamethasone Dexamethasone results in increased expression of SRGN mRNAincreases expression 12782123
D004041 Dietary Fats Dietary Fats results in increased expression of SRGN mRNAincreases expression 18042831
D004317 Doxorubicin SRGN protein affects the susceptibility to Doxorubicinaffects response to substance 16217747
D004997 Ethinyl Estradiol Ethinyl Estradiol results in decreased expression of SRGN mRNAdecreases expression 17557909
D016685 Mitomycin SRGN protein affects the susceptibility to Mitomycinaffects response to substance 16217747
D017239 Paclitaxel SRGN protein affects the susceptibility to Paclitaxelaffects response to substance 16217747
C041786 palm oil palm oil results in increased expression of SRGN mRNAincreases expression 18042831
D010634 Phenobarbital NR1I3 protein affects the reaction [Phenobarbital results in decreased expression of SRGN mRNA]affects reaction|decreases expression 19482888
D010634 Phenobarbital Phenobarbital results in decreased expression of SRGN mRNAdecreases expression 19482888
D019772 Topotecan SRGN protein affects the susceptibility to Topotecanaffects response to substance 16217747
D014212 Tretinoin Tretinoin results in increased expression of SRGN mRNAincreases expression 16604517
D014302 Trinitrobenzenesulfonic Acid Trinitrobenzenesulfonic Acid results in increased expression of SRGN mRNAincreases expression 17982090
D014747 Vinblastine SRGN protein affects the susceptibility to Vinblastineaffects response to substance 16217747
C025643 vinclozolin vinclozolin affects the expression of SRGN mRNAaffects expression 19015723
D002762 Cholecalciferol Cholecalciferol results in increased expression of SRGN mRNAincreases expression 17170073
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000014 Abnormalities, Drug-Induced Phenobarbital 3.316195326
MESH:D000138 Acidosis Ammonium Chloride 3.4318287403
MESH:D000152 Acne Vulgaris Ethinyl Estradiol 3.8117505938
MESH:D000230 Adenocarcinoma Doxorubicin 4.2817418594
MESH:D000230 Adenocarcinoma Ethinyl Estradiol 4.2814692618
MESH:D018248 Adenoma, Liver Cell Phenobarbital 3.8417620307
MESH:D000419 Albuminuria Doxorubicin 4.4221441931
MESH:D000505 Alopecia Tretinoin 3.5115955085
MESH:D000741 Anemia, Aplastic Benzene 4.2711369114 14761424 17661222
MESH:D000799 Angioedema Acetaminophen 3.7110982225
MESH:D001008 Anxiety Disorders vinclozolin 3.5319015723
MESH:D001161 Arteriosclerosis Dietary Fats 9.4715238619
MESH:D001161 Arteriosclerosis Ethinyl Estradiol 9.4711256880
MESH:D001169 Arthritis, Experimental Dexamethasone 11.8217659584
MESH:D001169 Arthritis, Experimental Ethinyl Estradiol 11.8215885639
MESH:D001169 Arthritis, Experimental Tretinoin 11.8216412693
MESH:D001172 Arthritis, Rheumatoid Tretinoin 2.2316292516
MESH:D001249 Asthma Tretinoin 2.3116456186
MESH:D001321 Autistic Disorder Acetaminophen 1.4318445737
MESH:D001327 Autoimmune Diseases Cholecalciferol 4.9016142846
MESH:D001471 Barrett Esophagus Tretinoin 4.2716935849
MESH:D001778 Blood Coagulation Disorders Tretinoin 3.4916206674 16197459
MESH:D001855 Bone Marrow Diseases Benzene 5.1016183116
MESH:D019046 Bone Marrow Neoplasms Doxorubicin 4.5714601052
MESH:D001859 Bone Neoplasms Paclitaxel 4.4415867366
MESH:D001932 Brain Neoplasms Doxorubicin 3.6917150277
MESH:D001943 Breast Neoplasms Benzene 2.9117162533 11921183
MESH:D001943 Breast Neoplasms decitabine 2.9119208741 18320071
MESH:D001943 Breast Neoplasms Dietary Fats 2.9120435547
MESH:D001943 Breast Neoplasms Doxorubicin 2.9118234424 15136595 18628466 15692762 15668708 17983394 19526202 18382427 16096432 16935488 16322301 15994142 16115903 15634643 17369602 11325840 16826403 18695136 15993339 17426702 16595493 15939500 15567936 16264153
MESH:D001943 Breast Neoplasms Paclitaxel 2.9118323546 15136595 18234424 16273361 18223236 16244791 11325840 16115903
MESH:D001943 Breast Neoplasms Tretinoin 2.9116443354 16166294 16873071
MESH:D001997 Bronchopulmonary Dysplasia Tretinoin 4.4616813970
MESH:D002276 Carcinoid Tumor Doxorubicin 4.6816051944
MESH:D018236 Carcinoma, Embryonal Tretinoin 5.0316168501
MESH:D006528 Carcinoma, Hepatocellular Acetaminophen 11.123084413
MESH:D006528 Carcinoma, Hepatocellular Aflatoxin B1 11.1221507988 12907637 12619106
MESH:D006528 Carcinoma, Hepatocellular Doxorubicin 11.1216023760 18059187 16234567 17876044
MESH:D006528 Carcinoma, Hepatocellular Paclitaxel 11.1216313753
MESH:D006528 Carcinoma, Hepatocellular Phenobarbital 11.1217173139 20007298 20935162 1701930 6705139
MESH:D006528 Carcinoma, Hepatocellular Tretinoin 11.121917145
MESH:D002292 Carcinoma, Renal Cell Doxorubicin 6.7516201981 1485588
MESH:D002292 Carcinoma, Renal Cell Vinblastine 6.751485588
MESH:D002294 Carcinoma, Squamous Cell decitabine 7.3919215824
MESH:D002294 Carcinoma, Squamous Cell Doxorubicin 7.396189445
MESH:D002294 Carcinoma, Squamous Cell Tretinoin 7.3916051514 16096774
MESH:D009202 Cardiomyopathies Doxorubicin 3.4417351982 17974986 18627295 17382496 16612575 15792986 16269455 15811867 16455267 17924179 17308081 16651473 17519947 16952015 17007740 16278810 16242529 17928571 15476868 17329180 16109756 16731534 15505089 17131338 16364871
MESH:D002311 Cardiomyopathy, Dilated Doxorubicin 2.9016243910 17334414
MESH:D002386 Cataract Acetaminophen 6.9710977129
MESH:D002386 Cataract Tretinoin 6.9717460283
MESH:D002471 Cell Transformation, Neoplastic Cyclosporine 6.8212371664
MESH:D002471 Cell Transformation, Neoplastic Cytarabine 6.828243401
MESH:D002493 Central Nervous System Diseases Phenobarbital 4.124080065
MESH:D018290 Cervical Intraepithelial Neoplasia Tretinoin 4.4616129372
MESH:D002779 Cholestasis Cyclosporine 7.4519486331
MESH:D002779 Cholestasis Ethinyl Estradiol 7.4516105132 11677210 17333356 16919318 15861022 17110522 17681005
MESH:D002822 Choriocarcinoma Tretinoin 5.0316461808
MESH:D002972 Cleft Palate Tretinoin 2.619407595
MESH:D003092 Colitis Tretinoin 9.3417035595
MESH:D003092 Colitis Trinitrobenzenesulfonic Acid 9.3417991707 16782535 11698051 16474422 16867261 16804969 17936198 18023891 18200517
MESH:D003093 Colitis, Ulcerative Trinitrobenzenesulfonic Acid 3.4017276891
MESH:D003110 Colonic Neoplasms decitabine 3.8817616700
MESH:D003110 Colonic Neoplasms Dexamethasone 3.8815824018
MESH:D015179 Colorectal Neoplasms decitabine 4.7818981723
MESH:D015179 Colorectal Neoplasms Doxorubicin 4.7818802399 18259882
MESH:D015179 Colorectal Neoplasms Paclitaxel 4.7818802399
MESH:D015179 Colorectal Neoplasms Vinblastine 4.7818802399
MESH:D019465 Craniofacial Abnormalities Benzene 3.8915643154
MESH:D019465 Craniofacial Abnormalities Dexamethasone 3.8917728286
MESH:D019465 Craniofacial Abnormalities Tretinoin 3.899211117 17551590 9224671 9664655 16925845 14991402 8800419 10589399 9125849 9142499
MESH:D003456 Cryptorchidism vinclozolin 4.2114966744
MESH:D003872 Dermatitis Benzene 4.6415902427
MESH:D017449 Dermatitis, Allergic Contact Dexamethasone 3.2812438553
MESH:D003967 Diarrhea Dexamethasone 3.577237001
MESH:D056486 Drug-Induced Liver Injury Acetaminophen 3.7719164858 16227642 11743745 16109766 12594235 15968718 11529661 17522070 10915739 11421492 17906064 19085960 18713872 12705907 11739529 12392966 11287661 16081117 18071297 19370779 14550746 16177239 12153990 15619225 12540782 16393943 10663392 19739265 17562736 12958197 19416960 19923254 19420014 14986274 10774834 11461765 14725611 16485898 16781746 11834606 2444490
MESH:D056486 Drug-Induced Liver Injury Doxorubicin 3.7717416283
MESH:D056487 Drug-Induced Liver Injury, Chronic Acetaminophen 3.9719426721
MESH:D004362 Drug Toxicity Doxorubicin 3.5718602426
MESH:D050171 Dyslipidemias Dietary Fats 3.3618367378
MESH:D004421 Dystonia Phenobarbital 3.881851702
MESH:D004485 Eczema Dexamethasone 4.3312438553
MESH:D004487 Edema Dexamethasone 3.2919703484
MESH:D004489 Edema, Cardiac Tretinoin 4.3418230668
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Ethinyl Estradiol 3.0612538720
MESH:D004701 Endocrine Gland Neoplasms decitabine 4.9919294695
MESH:D016889 Endometrial Neoplasms Doxorubicin 7.3017359293
MESH:D016889 Endometrial Neoplasms Tretinoin 7.3016569247
MESH:D004719 Endomyocardial Fibrosis Doxorubicin 5.0318037988
MESH:D004831 Epilepsies, Myoclonic Phenobarbital 3.983659116
MESH:D004828 Epilepsies, Partial Phenobarbital 3.743922381 11558140
MESH:D004827 Epilepsy Phenobarbital 2.8220417680
MESH:D004832 Epilepsy, Absence Phenobarbital 3.436401628
MESH:D017029 Epilepsy, Complex Partial Phenobarbital 4.127750514
MESH:D004830 Epilepsy, Tonic-Clonic Phenobarbital 3.893659116
MESH:D004938 Esophageal Neoplasms Paclitaxel 2.8616481741
MESH:D005124 Eye Abnormalities Tretinoin 3.4816938888 9664655
MESH:D005234 Fatty Liver Cyclosporine 12.3719224547
MESH:D005234 Fatty Liver Dietary Fats 12.3719004024 19551842 18296743 17967931
MESH:D005234 Fatty Liver Ethinyl Estradiol 12.3715345470
MESH:D018222 Fibromatosis, Aggressive Doxorubicin 4.4619069698
MESH:D005355 Fibrosis Cyclosporine 20.1312639820 12168785
MESH:D005355 Fibrosis Dietary Fats 20.1318296743
MESH:D005355 Fibrosis Tretinoin 20.1317994277
MESH:D005355 Fibrosis Trinitrobenzenesulfonic Acid 20.1317994277
MESH:D005756 Gastritis Acetaminophen 3.5516983495
MESH:D030342 Genetic Diseases, Inborn vinclozolin 4.8016973722
MESH:D005832 Genital Diseases, Male vinclozolin 5.1716417039
MESH:D005885 Gingival Hyperplasia Cyclosporine 4.098708960
MESH:D005909 Glioblastoma Doxorubicin 6.9617150277
MESH:D005909 Glioblastoma Tretinoin 6.9617312396
MESH:D006258 Head and Neck Neoplasms decitabine 12.4819215824
MESH:D006258 Head and Neck Neoplasms Doxorubicin 12.4815692506
MESH:D006258 Head and Neck Neoplasms Tretinoin 12.4816096774
MESH:D006317 Hearing Loss, Noise-Induced Tretinoin 5.0316084493
MESH:D006330 Heart Defects, Congenital Tretinoin 2.8314991402 9664655
MESH:D006331 Heart Diseases Doxorubicin 3.3916244372 16144979 18006777 17875725 16244371 16495754 18674790 16330681 14766674 16707910 12587719 16879835 17888722
MESH:D006333 Heart Failure Doxorubicin 3.2617481944
MESH:D006394 Hemangiosarcoma Doxorubicin 3.7815692506
MESH:D006402 Hematologic Diseases Benzene 4.5316183116
MESH:D006457 Hemoglobinuria, Paroxysmal Cyclosporine 4.2915720958
MESH:D006529 Hepatomegaly Phenobarbital 3.3616109766
MESH:D006548 Hernia, Diaphragmatic Dexamethasone 3.037520565
MESH:D006689 Hodgkin Disease Cytarabine 11.9216200630
MESH:D006689 Hodgkin Disease Doxorubicin 11.9218501091 15147373 17606976
MESH:D006689 Hodgkin Disease Vinblastine 11.9218501091 18180244
MESH:D006930 Hyperalgesia Acetaminophen 7.2816870215
MESH:D006930 Hyperalgesia Tretinoin 7.2816870215
MESH:D006937 Hypercholesterolemia Dietary Fats 3.4721332399
MESH:D017681 Hypereosinophilic Syndrome Tretinoin 4.4416778211
MESH:D006949 Hyperlipidemias Dietary Fats 3.4921332399
MESH:D006973 Hypertension Benzene 8.4617940673
MESH:D006973 Hypertension Cyclosporine 8.4610903974
MESH:D006973 Hypertension Dexamethasone 8.4617042910
MESH:D007021 Hypospadias Ethinyl Estradiol 3.6816569931 16945680
MESH:D007247 Infertility, Female Ethinyl Estradiol 3.3412013081
MESH:D007248 Infertility, Male decitabine 10.7317581917
MESH:D007248 Infertility, Male Ethinyl Estradiol 10.7317937319
MESH:D007248 Infertility, Male vinclozolin 10.7316467254
MESH:D007249 Inflammation Dexamethasone 5.0711099482 8960868
MESH:D007249 Inflammation Dietary Fats 5.0720412841
MESH:D015212 Inflammatory Bowel Diseases Trinitrobenzenesulfonic Acid 3.5318200517
MESH:D007333 Insulin Resistance Dietary Fats 3.0218457598 11836018
MESH:D007410 Intestinal Diseases Tretinoin 9.5517994277
MESH:D007410 Intestinal Diseases Trinitrobenzenesulfonic Acid 9.5517994277
MESH:D007569 Jaw Abnormalities Tretinoin 3.7817551590 15992940
MESH:D007638 Keratoconjunctivitis Sicca Cyclosporine 4.3115604871
MESH:D007674 Kidney Diseases Acetaminophen 9.6012587719 15629191
MESH:D007674 Kidney Diseases Cyclosporine 9.608314463 10903974 18776723
MESH:D007674 Kidney Diseases Doxorubicin 9.6015699352 15369732 16775033
MESH:D007676 Kidney Failure, Chronic Doxorubicin 4.0316707910
MESH:D007680 Kidney Neoplasms Cyclosporine 2.6312371664
MESH:D007938 Leukemia Benzene 10.2114694614 15935818 18335105 17119257
MESH:D007938 Leukemia decitabine 10.2119235587 18980019
MESH:D007938 Leukemia Tretinoin 10.2117143497
MESH:D004915 Leukemia, Erythroblastic, Acute Doxorubicin 5.0316085563
MESH:D007951 Leukemia, Myeloid Benzene 15.3817506065
MESH:D007951 Leukemia, Myeloid decitabine 15.3818454857 19117987 17236224
MESH:D007951 Leukemia, Myeloid Tretinoin 15.3816932348 16482212 19285840
MESH:D015470 Leukemia, Myeloid, Acute Benzene 6.0819478238
MESH:D015470 Leukemia, Myeloid, Acute decitabine 6.0819387464 18460780 19010910 17679729 18206229 18704418
MESH:D015470 Leukemia, Myeloid, Acute Tretinoin 6.0816294345 19850784 17596541
MESH:D015477 Leukemia, Myelomonocytic, Chronic decitabine 5.3318055864
MESH:D015473 Leukemia, Promyelocytic, Acute Tretinoin 3.0717107899 19225113 19035177 12679006 17649720 16766008 9834237 17294898 17339181 16788101 17712046 19029980 19642359 17506722 15748426 16823087 19075265 16935935 17368321 17301526 17217047 17361223 16140955 16331271 16891316
MESH:D007984 Leydig Cell Tumor vinclozolin 4.6016417039
MESH:D017880 Limb Deformities, Congenital Tretinoin 3.219224671
MESH:D008080 Liposarcoma Paclitaxel 4.7017353645
MESH:D008103 Liver Cirrhosis Dietary Fats 6.4218296743
MESH:D008103 Liver Cirrhosis Phenobarbital 6.4221047994
MESH:D008106 Liver Cirrhosis, Experimental Dexamethasone 3.5616718785
MESH:D008106 Liver Cirrhosis, Experimental Doxorubicin 3.5616439617 16595196
MESH:D008106 Liver Cirrhosis, Experimental Tretinoin 3.5616248980 18397230
MESH:D008107 Liver Diseases Acetaminophen 3.8212587719 19460945 16610002 19014921 19784758 12969438 11587558 16611625
MESH:D008107 Liver Diseases Phenobarbital 3.8219363144
MESH:D017114 Liver Failure, Acute Acetaminophen 3.1217185352 16871587
MESH:D008113 Liver Neoplasms Aflatoxin B1 7.3418177683 15890375 2125692 9163691
MESH:D008113 Liver Neoplasms Mitomycin 7.3415113037
MESH:D008113 Liver Neoplasms Phenobarbital 7.3421047994 19073162 15975961 19482888 19812893 8742319
MESH:D008114 Liver Neoplasms, Experimental Aflatoxin B1 13.528603461
MESH:D008114 Liver Neoplasms, Experimental Benzene 13.5212562636
MESH:D008114 Liver Neoplasms, Experimental Doxorubicin 13.5216842330 17085340
MESH:D008114 Liver Neoplasms, Experimental Phenobarbital 13.5217172636 1399818 2563599 18308698 6150874
MESH:D017563 Lung Diseases, Interstitial Benzene 4.6814698565
MESH:D008175 Lung Neoplasms Aflatoxin B1 4.8114755239
MESH:D008175 Lung Neoplasms Benzene 4.8112562636
MESH:D008175 Lung Neoplasms Dexamethasone 4.8111195469 15824018
MESH:D008175 Lung Neoplasms Doxorubicin 4.816189445 17418594
MESH:D008223 Lymphoma Benzene 12.1317119257 17584886
MESH:D008223 Lymphoma decitabine 12.1319470736
MESH:D008223 Lymphoma Doxorubicin 12.1316098063
MESH:D008228 Lymphoma, Non-Hodgkin Doxorubicin 8.6017654614
MESH:D008228 Lymphoma, Non-Hodgkin Paclitaxel 8.6014749477
MESH:D016399 Lymphoma, T-Cell Doxorubicin 4.4415621674
MESH:D015674 Mammary Neoplasms, Animal Benzene 4.3112562636
MESH:D008325 Mammary Neoplasms, Experimental Benzene 6.1211921183
MESH:D008325 Mammary Neoplasms, Experimental Doxorubicin 6.1215458769
MESH:D008527 Medulloblastoma Tretinoin 2.7317453147
MESH:D008545 Melanoma decitabine 9.5816505122 17785578
MESH:D008545 Melanoma Doxorubicin 9.5816827129
MESH:D008545 Melanoma Paclitaxel 9.5812025231 16342250 12040289
MESH:D008545 Melanoma Tretinoin 9.5816752155
MESH:D008545 Melanoma Vinblastine 9.5816432458 16809738 18332650 18176117 16248763 15577323 12374674 18505091 17761969 15577320
MESH:D008546 Melanoma, Experimental Acetaminophen 3.4419513568
MESH:D008591 Meningomyelocele Tretinoin 4.2916940565
MESH:D008654 Mesothelioma Doxorubicin 3.0117638057
MESH:D008664 Metal Metabolism, Inborn Errors Cyclosporine 4.6616801185
MESH:D028361 Mitochondrial Diseases Doxorubicin 4.3815792986
MESH:D052016 Mucositis Doxorubicin 4.6617415656
MESH:D009101 Multiple Myeloma Benzene 16.5717119195
MESH:D009101 Multiple Myeloma decitabine 16.5718172295
MESH:D009101 Multiple Myeloma Dexamethasone 16.5715744524 16118317 15867202
MESH:D009101 Multiple Myeloma Paclitaxel 16.5714749477
MESH:D009190 Myelodysplastic Syndromes decitabine 11.9719157545 19010910 16882708 18608210
MESH:D009190 Myelodysplastic Syndromes Dexamethasone 11.979809623
MESH:D009190 Myelodysplastic Syndromes Tretinoin 11.9717596541
MESH:D009203 Myocardial Infarction Doxorubicin 2.9019429709 15857846
MESH:D020191 Myoclonic Epilepsies, Progressive Phenobarbital 4.3417484760
MESH:D009362 Neoplasm Metastasis Doxorubicin 5.9618259882
MESH:D009362 Neoplasm Metastasis Paclitaxel 5.9615867366
MESH:D009369 Neoplasms decitabine 4.9819470736 19116145 17925555
MESH:D009369 Neoplasms Tretinoin 4.9816946489 16594593
MESH:D009401 Nephrosis Doxorubicin 4.6416899518 16636307
MESH:D009402 Nephrosis, Lipoid Cyclosporine 4.3117954296
MESH:D009404 Nephrotic Syndrome Cyclosporine 8.9219348381 18481113
MESH:D009404 Nephrotic Syndrome Doxorubicin 8.9215640375 16889571
MESH:D009421 Nervous System Malformations Tretinoin 3.659125849
MESH:D009436 Neural Tube Defects Benzene 7.2215643154
MESH:D009436 Neural Tube Defects Tretinoin 7.229142499
MESH:D009447 Neuroblastoma Doxorubicin 7.0715555623
MESH:D009447 Neuroblastoma Topotecan 7.0715176712
MESH:D019636 Neurodegenerative Diseases Acetaminophen 2.7618514411
MESH:D009503 Neutropenia Vinblastine 4.4517378895
MESH:D009765 Obesity Dietary Fats 2.2618674790 11836018 19632207 17217161 16723640 20518802 21332399 18457598 20132043
MESH:D009784 Occupational Diseases Benzene 4.0617119257 15935809 15727169 17479406 15612468 15576619 16737584 15913788 17178637
MESH:D010014 Osteolysis Paclitaxel 4.8515867366
MESH:D010018 Osteomalacia Phenobarbital 4.2317016548
MESH:D012516 Osteosarcoma Doxorubicin 4.0115930896
MESH:D010051 Ovarian Neoplasms Benzene 11.0312562636
MESH:D010051 Ovarian Neoplasms decitabine 11.0319331143 19259094
MESH:D010051 Ovarian Neoplasms Paclitaxel 11.0311161223
MESH:D010051 Ovarian Neoplasms Tretinoin 11.0316936753
MESH:D010146 Pain Acetaminophen 6.2316870215
MESH:D010146 Pain Tretinoin 6.2316870215
MESH:D010190 Pancreatic Neoplasms decitabine 12.0119294695
MESH:D010190 Pancreatic Neoplasms Mitomycin 12.0115113037
MESH:D010190 Pancreatic Neoplasms Phenobarbital 12.0116965848
MESH:D010190 Pancreatic Neoplasms Tretinoin 12.0115976015
MESH:D010195 Pancreatitis Trinitrobenzenesulfonic Acid 4.0817698068
MESH:D016584 Panic Disorder Ethinyl Estradiol 3.5611578682
MESH:D003557 Phyllodes Tumor Doxorubicin 5.0317983394
MESH:D010997 Pleural Neoplasms Doxorubicin 5.0317638057
MESH:D011230 Precancerous Conditions Cyclosporine 8.6012371664
MESH:D011230 Precancerous Conditions Phenobarbital 8.602563599
MESH:D054198 Precursor Cell Lymphoblastic Leukemia-Lymphoma Cytarabine 7.8121297632
MESH:D054198 Precursor Cell Lymphoblastic Leukemia-Lymphoma Dexamethasone 7.8121297632
MESH:D011297 Prenatal Exposure Delayed Effects vinclozolin 3.7719015723 18220299 18042343
MESH:D055728 Primary Myelofibrosis decitabine 4.6017616702
MESH:D011469 Prostatic Diseases vinclozolin 4.8018220299
MESH:D011471 Prostatic Neoplasms Cholecalciferol 2.8717024972
MESH:D011471 Prostatic Neoplasms Doxorubicin 2.8716888761 16729912 16868541 15897917 15749863 18437689
MESH:D011471 Prostatic Neoplasms Paclitaxel 2.8717172428 17136230 16356831 16729912
MESH:D011472 Prostatitis vinclozolin 4.8018629315
MESH:D011507 Proteinuria Tretinoin 3.4816636307
MESH:D011537 Pruritus Ethinyl Estradiol 3.1816919318 15861022
MESH:D019310 Pseudolymphoma Phenobarbital 4.3712752131
MESH:D011565 Psoriasis Cyclosporine 2.1816882103
MESH:D011625 Pterygium Tretinoin 4.6616723453
MESH:D051437 Renal Insufficiency Doxorubicin 4.0917922066
MESH:D012128 Respiratory Distress Syndrome, Adult Dexamethasone 3.8918379247 11700416
MESH:D012208 Rhabdomyosarcoma decitabine 10.5319155313
MESH:D012208 Rhabdomyosarcoma Tretinoin 10.5316116481 16283617
MESH:D012509 Sarcoma Doxorubicin 3.8718313854 17710206 15675481 17203757 16767912 15625365
MESH:D012512 Sarcoma, Ewing's Doxorubicin 4.1116326096 14601052
MESH:D012514 Sarcoma, Kaposi Doxorubicin 4.6617846226
MESH:D012640 Seizures Phenobarbital 2.614039156 3137016 16876388 11442880
MESH:D003294 Seizures, Febrile Phenobarbital 4.696407741
MESH:D012878 Skin Neoplasms Doxorubicin 9.2015692506
MESH:D012878 Skin Neoplasms tert-Butylhydroperoxide 9.208532709
MESH:D012878 Skin Neoplasms Tretinoin 9.2016467112
MESH:D012983 Soft Tissue Neoplasms Doxorubicin 4.4415625365 17203757 16767912
MESH:D013088 Spermatocele Ethinyl Estradiol 3.8116709447
MESH:D013272 Stomach Diseases Dexamethasone 4.1915472012
MESH:D013274 Stomach Neoplasms Benzene 4.6912562636
MESH:D013274 Stomach Neoplasms decitabine 4.6919037991
MESH:D013274 Stomach Neoplasms Paclitaxel 4.6918506536 18396642
MESH:D013274 Stomach Neoplasms Tretinoin 4.6917261132
MESH:D013276 Stomach Ulcer Dexamethasone 3.3715138204
MESH:D024801 Tauopathies Paclitaxel 4.6816930453
MESH:D019851 Thrombophilia Ethinyl Estradiol 3.5011994571
MESH:D013927 Thrombosis Ethinyl Estradiol 3.0415669648
MESH:D013953 Thymus Neoplasms Benzene 4.8210850423
MESH:D013964 Thyroid Neoplasms decitabine 16.3117967635
MESH:D013964 Thyroid Neoplasms Doxorubicin 16.3117909728 16010429
MESH:D013964 Thyroid Neoplasms Phenobarbital 16.311399818
MESH:D013964 Thyroid Neoplasms Tretinoin 16.3116026305 17045167
MESH:D014062 Tongue Neoplasms Tretinoin 3.6716051514
MESH:D014376 Tuberculosis Tretinoin 3.1516040207
MESH:D001749 Urinary Bladder Neoplasms decitabine 5.1817616700 19087683
MESH:D001749 Urinary Bladder Neoplasms Doxorubicin 5.1817653716
MESH:D014581 Urticaria Acetaminophen 2.8510982225
MESH:D002583 Uterine Cervical Neoplasms Tretinoin 3.5616129372
MESH:D014594 Uterine Neoplasms Benzene 9.1512562636
MESH:D014594 Uterine Neoplasms Ethinyl Estradiol 9.1514692618
MESH:D014604 Uveal Neoplasms decitabine 12.4017785578
MESH:D014604 Uveal Neoplasms Tretinoin 12.4016752155
MESH:D014605 Uveitis Cyclosporine 11.341336536
MESH:D014605 Uveitis Dexamethasone 11.341336536
MESH:D014625 Vaginal Neoplasms Vinblastine 4.9115577323
MESH:D020246 Venous Thrombosis Ethinyl Estradiol 3.4215869587 14671159
MESH:D018487 Ventricular Dysfunction, Left Doxorubicin 4.0916364871 17678736 17638931 17334414
MESH:D014820 Vitiligo Tretinoin 3.9316761959
MESH:D015430 Weight Gain Dietary Fats 3.6216723640
MESH:D009396 Wilms Tumor Tretinoin 3.8516287080
MESH:D014985 Xerophthalmia Cyclosporine 4.3117120751
Pathway ID Pathway Name
REACT:604 Hemostasis
Pharmacogenomics Knowledge Base Top
  • PharmGKB Accession:PA33733
    • No data
    Releated disease ID Related disease Name
    PA446155Precursor Cell Lymphoblastic Leukemia-Lymphoma
    Releated drug ID Related drug Name
    PA450379mercaptopurine
    PA450428methotrexate
    Drug Bank Top

    Simple Query:


      (e.g. CHD8)

    Syndromic Genes

    Non-syndromic Genes

    AutismKB Statistics

    • Studies: 1,036
    • Genes: 1,379
    • CNVs/SVs: 5,420
    • SNVs/Indels: 11,669
    • de novo Mutations: 5,669
    • Mosaics: 789
    • Linkage Regions: 172
    • Paper Collected: 6/30/2018
    • Last Update: 8/26/2018


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