AutismKB 2.0

Annotation Detail for TRIM36


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:TRIM36 ( HAPRIN,RBCC728,RNF98 )
Gene Full Name: tripartite motif-containing 36
Band: 5q22.3
Quick LinksEntrez ID:55521; OMIM: 609317; Uniprot ID:TRI36_HUMAN; ENSEMBL ID: ENSG00000152503; HGNC ID: 16280
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
Related Diseases/Disorders Top
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
D000082 Acetaminophen Acetaminophen affects the expression of TRIM36 mRNAaffects expression 17562736
D000638 Amiodarone Amiodarone results in increased expression of TRIM36 mRNAincreases expression 19774075
D020849 Raloxifene [Raloxifene co-treated with ESR2 protein] results in increased expression of TRIM36 mRNAaffects cotreatment|increases expression 19059307
D012643 Selenium Selenium results in decreased expression of TRIM36 mRNAdecreases expression 19244175
D013629 Tamoxifen [Tamoxifen co-treated with ESR2 protein] results in increased expression of TRIM36 mRNAaffects cotreatment|increases expression 19059307
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000008 Abdominal Neoplasms Tamoxifen 5.1614745880
MESH:D000419 Albuminuria Raloxifene 5.0417308373 17451421
MESH:D000544 Alzheimer Disease Raloxifene 2.6015800139
MESH:D000799 Angioedema Acetaminophen 4.4510982225
MESH:D001145 Arrhythmias, Cardiac Amiodarone 4.1518057881 20041841 18218290
MESH:D001281 Atrial Fibrillation Amiodarone 4.1618651412 19698954
MESH:D001321 Autistic Disorder Acetaminophen 1.4018445737
MESH:D001778 Blood Coagulation Disorders Amiodarone 4.2719483382
MESH:D001930 Brain Injuries Raloxifene 4.9616580743
MESH:D001943 Breast Neoplasms Raloxifene 2.2816837676 17440819 17242785 17893378 17049068 15572757 15758505 17952589 17595753 17261762 16912660 15775269
MESH:D001943 Breast Neoplasms Tamoxifen 2.2818984771 15668708 19487384 17261762 18821012 19288272 18629630 21138602 19066611 17893378 21152245 19189210 17440819 18815881 20135344 19189212 16202921 19011961 19244106 20544844 16818667 15565566 18425577 19410462 19200415 19115204 19103187 19221464 18351453 19084267 19289846 20390343 11161223 18997820 18855134 20065188 19155303 16273361 19142967 16873071 19059307 20005174 17049068 20859285 17242785
MESH:D018270 Carcinoma, Ductal, Breast Tamoxifen 4.9919066611
MESH:D006528 Carcinoma, Hepatocellular Acetaminophen 2.973084413
MESH:D006528 Carcinoma, Hepatocellular Tamoxifen 2.9716924424
MESH:D002295 Carcinoma, Transitional Cell Raloxifene 10.6817572228
MESH:D002295 Carcinoma, Transitional Cell Tamoxifen 10.6817572228
MESH:D002311 Cardiomyopathy, Dilated Amiodarone 2.9919225199 15710769
MESH:D002318 Cardiovascular Diseases Raloxifene 3.6815775269
MESH:D002341 Carotid Artery Thrombosis Amiodarone 5.6218974383
MESH:D002386 Cataract Acetaminophen 2.7710977129
MESH:D003072 Cognition Disorders Raloxifene 5.1015800139
MESH:D003092 Colitis Selenium 4.2617936198
MESH:D003110 Colonic Neoplasms marker/mechanism 19050079
MESH:D003711 Demyelinating Diseases Tamoxifen 4.8519031437
MESH:D003865 Depressive Disorder, Major Raloxifene 4.4917474826
MESH:D003928 Diabetic Nephropathies Raloxifene 10.1315920148 17451421 17308373
MESH:D003928 Diabetic Nephropathies Tamoxifen 10.1319279558
MESH:D056486 Drug-Induced Liver Injury Acetaminophen 6.7610774834 11529661 11421492 14725611 11743745 12540782 19085960 19739265 19420014 11461765 17522070 10915739 15968718 17906064 14986274 19416960 11739529 14550746 10663392 12705907 12153990 16781746 16393943 18071297 12594235 11287661 17562736 16227642 16081117 11834606 16177239 16485898 19164858 15619225 12958197 2444490 19923254 12392966 19370779 16109766 18713872
MESH:D056486 Drug-Induced Liver Injury Amiodarone 6.7618218290 15265979
MESH:D056486 Drug-Induced Liver Injury Selenium 6.7615131321
MESH:D056487 Drug-Induced Liver Injury, Chronic Acetaminophen 4.7119426721
MESH:D004487 Edema Raloxifene 3.7015860553
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Raloxifene 10.7515845917
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Tamoxifen 10.7519031437
MESH:D016889 Endometrial Neoplasms Tamoxifen 3.2617893378 19155303 16202921 20544844
MESH:D005234 Fatty Liver Amiodarone 15.5214986274
MESH:D005234 Fatty Liver Raloxifene 15.5217473493
MESH:D005234 Fatty Liver Tamoxifen 15.5219224547 14986274
MESH:D052776 Female Urogenital Diseases Tamoxifen 3.4316709447
MESH:D018221 Fibromatosis, Abdominal Tamoxifen 5.0714745880
MESH:D018222 Fibromatosis, Aggressive Tamoxifen 4.7219069698
MESH:D005756 Gastritis Acetaminophen 4.2916983495
MESH:D006331 Heart Diseases Raloxifene 3.7711110106
MESH:D006333 Heart Failure Selenium 3.2717162251
MESH:D006529 Hepatomegaly Amiodarone 4.2315265979
MESH:D006930 Hyperalgesia Acetaminophen 2.9916870215
MESH:D006937 Hypercholesterolemia Amiodarone 4.258137927 9751232
MESH:D006973 Hypertension Raloxifene 2.9717577099 15787275
MESH:D007037 Hypothyroidism Amiodarone 5.0017991464 18020914
MESH:D007249 Inflammation Tamoxifen 2.5119457130
MESH:D007251 Influenza, Human Selenium 4.8116624496
MESH:D007674 Kidney Diseases Acetaminophen 2.3812587719 15629191
MESH:D007676 Kidney Failure, Chronic Selenium 4.2616518626
MESH:D007680 Kidney Neoplasms Tamoxifen 3.3518625569
MESH:D007889 Leiomyoma Raloxifene 4.9016973256
MESH:D008064 Lipidoses Amiodarone 8.7515342952 17567588
MESH:D008064 Lipidoses Tamoxifen 8.7515342952 17567588
MESH:D008106 Liver Cirrhosis, Experimental Tamoxifen 1.7518564211
MESH:D008107 Liver Diseases Acetaminophen 1.6919460945 12969438 19784758 16611625 19014921 12587719 11587558 16610002
MESH:D017114 Liver Failure, Acute Acetaminophen 3.5817185352 16871587
MESH:D008113 Liver Neoplasms Tamoxifen 2.3216684651
MESH:D008133 Long QT Syndrome Amiodarone 3.8515350150 17391786 11989578
MESH:D008171 Lung Diseases Amiodarone 3.6012587719
MESH:D017563 Lung Diseases, Interstitial Amiodarone 5.0918516814
MESH:D008175 Lung Neoplasms Tamoxifen 1.7418625569
MESH:D015674 Mammary Neoplasms, Animal Tamoxifen 4.3019428831
MESH:D008325 Mammary Neoplasms, Experimental Selenium 6.7615318939
MESH:D008325 Mammary Neoplasms, Experimental Tamoxifen 6.7616827153 11731420 19196722 14580682 19196723
MESH:D020149 Manganese Poisoning Tamoxifen 5.1619453300
MESH:D008545 Melanoma Tamoxifen 1.9219393235 12393984
MESH:D018328 Melanoma, Amelanotic Tamoxifen 4.7215990972
MESH:D008546 Melanoma, Experimental Acetaminophen 4.0519513568
MESH:D008654 Mesothelioma Selenium 2.9015107826
MESH:D018200 Mixed Tumor, Mullerian Raloxifene 6.1715863610
MESH:D009101 Multiple Myeloma Raloxifene 3.6816497877
MESH:D009181 Mycoses Amiodarone 5.5112754197 17974566
MESH:D009232 Myxoma Raloxifene 6.1716343187
MESH:D009362 Neoplasm Metastasis Tamoxifen 2.6619393235
MESH:D009364 Neoplasm Recurrence, Local marker/mechanism 19050079
MESH:D009364 Neoplasm Recurrence, Local Tamoxifen 2.6019410462
MESH:D009376 Neoplasms, Hormone-Dependent Tamoxifen 4.6119200415 19189210 19196722
MESH:D019636 Neurodegenerative Diseases Acetaminophen 3.1818514411
MESH:D010024 Osteoporosis Raloxifene 3.5919059307 17882678 15775268
MESH:D015663 Osteoporosis, Postmenopausal Raloxifene 4.6317893378 15579764 15758505 17823083
MESH:D010146 Pain Acetaminophen 2.6916870215
MESH:D010954 Plasmacytoma Selenium 5.5015087411
MESH:D011471 Prostatic Neoplasms Raloxifene 3.2915731164 16536755 16220300
MESH:D011471 Prostatic Neoplasms Tamoxifen 3.2915067354
MESH:D011658 Pulmonary Fibrosis Amiodarone 2.9611597910 12832656 12490602
MESH:D011693 Purpura Raloxifene 6.1715770314
OMIM:609620 SHORT QT SYNDROME 1 Amiodarone 5.6218724381
MESH:D013088 Spermatocele Tamoxifen 4.9016709447
MESH:D013119 Spinal Cord Injuries Tamoxifen 4.5819457130
MESH:D013276 Stomach Ulcer Amiodarone 3.6818087811
MESH:D020521 Stroke Raloxifene 4.1116837676
MESH:D013610 Tachycardia Amiodarone 4.7311238279
MESH:D017180 Tachycardia, Ventricular Amiodarone 4.6319225199
MESH:D013959 Thyroid Diseases Amiodarone 5.3719731979
MESH:D013971 Thyrotoxicosis Amiodarone 5.3418020914 19584973
MESH:D013978 Tibial Fractures Raloxifene 5.8219048282
MESH:D016171 Torsades de Pointes Amiodarone 4.7311989578 17467628
MESH:D001749 Urinary Bladder Neoplasms Raloxifene 5.6117572228
MESH:D001749 Urinary Bladder Neoplasms Tamoxifen 5.6117572228 8653321 16712894
MESH:D014581 Urticaria Acetaminophen 3.3810982225
MESH:D054556 Venous Thromboembolism Raloxifene 5.8216837676
MESH:D014846 Vulvar Neoplasms Raloxifene 6.1716343187
No data
Pharmacogenomics Knowledge Base Top
Drug Bank Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


Copyright © 2017, Center for Bioinformatics , Peking University | All Rights Reserved