AutismKB 2.0

Annotation Detail for MAML3


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Basic Information Top
Gene Symbol:MAML3 ( CAGH3,ERDA3,GDN,MAM-2,MAM2,TNRC3 )
Gene Full Name: mastermind-like 3 (Drosophila)
Band: 4q31.1
Quick LinksEntrez ID:55534; OMIM: 608991; Uniprot ID:MAML3_HUMAN; ENSEMBL ID: ENSG00000196782; HGNC ID: 16272
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
No data
Pathway IDPathway Name
hsa04330Notch signaling pathway
Pathway IDPathway Name
Gene Expression
No data
No data
No data
Related Diseases/Disorders Top
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
D017638 Asbestos, Crocidolite Asbestos, Crocidolite affects the expression of MAML3 mRNAaffects expression 17331233
D015123 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide affects the expression of MAML3 mRNAaffects expression 20382639
D015735 Mifepristone Mifepristone results in increased expression of MAML3 mRNAincreases expression 17584828
D018038 Sodium Selenite Sodium Selenite results in decreased expression of MAML3 mRNAdecreases expression 18175754
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D002471 Cell Transformation, Neoplastic 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 2.9820889678
MESH:D019457 Chromosome Breakage Sodium Selenite 5.3115894690
MESH:D003920 Diabetes Mellitus Sodium Selenite 4.1516285004
MESH:D056486 Drug-Induced Liver Injury Sodium Selenite 2.3615131321
MESH:D004715 Endometriosis Mifepristone 4.7616134523
MESH:D004938 Esophageal Neoplasms 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 2.1520426865
MESH:D007333 Insulin Resistance Sodium Selenite 3.5214714311
MESH:D055370 Lung Injury Asbestos, Crocidolite 4.5817365036
MESH:D016393 Lymphoma, B-Cell Sodium Selenite 4.5214737004
MESH:D008654 Mesothelioma Asbestos, Crocidolite 3.3116166281 16966607 18303189
MESH:D010051 Ovarian Neoplasms Mifepristone 3.2216525653
MESH:D010995 Pleural Diseases Asbestos, Crocidolite 5.4510923243
MESH:D011471 Prostatic Neoplasms Sodium Selenite 3.3318760546
MESH:D011658 Pulmonary Fibrosis Asbestos, Crocidolite 3.1517365031 15814490 17975199 17322281
Pathway ID Pathway Name
REACT:71 Gene Expression
KEGG:04330 Notch signaling pathway
Pharmacogenomics Knowledge Base Top
Drug Bank Top

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Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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