AutismKB 2.0

Annotation Detail for CDCA7L


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Basic Information Top
Gene Symbol:CDCA7L ( DKFZp762L0311,JPO2,R1,RAM2 )
Gene Full Name: cell division cycle associated 7-like
Band: 7p15.3
Quick LinksEntrez ID:55536; OMIM: 609685; Uniprot ID:CDA7L_HUMAN; ENSEMBL ID: ENSG00000164649; HGNC ID: 30777
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
Related Diseases/Disorders Top
No data
No data
Desease Name
height
CHEMDEPENDENCY
smoking cessation
DEVELOPMENTAL
Desease Name
Height
No data
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
D016604 Aflatoxin B1 Aflatoxin B1 affects the expression of CDCA7L proteinaffects expression 20106945
D001564 Benzo(a)pyrene Benzo(a)pyrene results in decreased expression of CDCA7L mRNAdecreases expression 20064835
D016572 Cyclosporine Cyclosporine results in increased expression of CDCA7L mRNAincreases expression 20106945
D013629 Tamoxifen Tamoxifen results in increased expression of CDCA7L mRNAincreases expression 17555576
D014212 Tretinoin Tretinoin results in decreased expression of CDCA7L mRNAdecreases expression 17218384
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000008 Abdominal Neoplasms Tamoxifen 5.1614745880
MESH:D000230 Adenocarcinoma Benzo(a)pyrene 2.0520464547 20127859
MESH:D000236 Adenoma Benzo(a)pyrene 2.846695378
MESH:D000505 Alopecia Tretinoin 3.9015955085
MESH:D017544 Aortic Aneurysm, Abdominal Benzo(a)pyrene 4.5619183758
MESH:D001169 Arthritis, Experimental Tretinoin 3.2816412693
MESH:D001172 Arthritis, Rheumatoid Tretinoin 2.3316292516
MESH:D001249 Asthma Tretinoin 2.4316456186
MESH:D001471 Barrett Esophagus Tretinoin 4.8416935849
MESH:D001778 Blood Coagulation Disorders Tretinoin 3.9816206674 16197459
MESH:D001943 Breast Neoplasms Benzo(a)pyrene 1.8717474063 20146248
MESH:D001943 Breast Neoplasms Tamoxifen 1.8717049068 20005174 19084267 18984771 19410462 17242785 19487384 19289846 21138602 18821012 15668708 18997820 16873071 19066611 17440819 11161223 17893378 19155303 18351453 20065188 19221464 19103187 18855134 21152245 19115204 16818667 19011961 19244106 16202921 18425577 20544844 16273361 19189212 20390343 19189210 20135344 19142967 19288272 15565566 20859285 18815881 17261762 19059307 18629630 19200415
MESH:D001943 Breast Neoplasms Tretinoin 1.8716443354 16873071 16166294
MESH:D001997 Bronchopulmonary Dysplasia Tretinoin 5.1316813970
MESH:D018270 Carcinoma, Ductal, Breast Tamoxifen 4.9919066611
MESH:D018236 Carcinoma, Embryonal Tretinoin 5.7716168501
MESH:D006528 Carcinoma, Hepatocellular Aflatoxin B1 4.8612619106 12907637 21507988
MESH:D006528 Carcinoma, Hepatocellular Tamoxifen 4.8616924424
MESH:D006528 Carcinoma, Hepatocellular Tretinoin 4.861917145
MESH:D002294 Carcinoma, Squamous Cell Benzo(a)pyrene 4.8420419170
MESH:D002294 Carcinoma, Squamous Cell Tretinoin 4.8416096774 16051514
MESH:D002295 Carcinoma, Transitional Cell Tamoxifen 3.9617572228
MESH:D002386 Cataract Tretinoin 3.2817460283
MESH:D002471 Cell Transformation, Neoplastic Cyclosporine 2.7612371664
MESH:D018290 Cervical Intraepithelial Neoplasia Tretinoin 5.1316129372
MESH:D002779 Cholestasis Cyclosporine 3.1719486331
MESH:D002822 Choriocarcinoma Tretinoin 5.7716461808
MESH:D002972 Cleft Palate Tretinoin 2.799407595
MESH:D003092 Colitis Tretinoin 4.1917035595
MESH:D019465 Craniofacial Abnormalities Tretinoin 1.8316925845 9211117 10589399 9142499 8800419 9224671 17551590 14991402 9125849 9664655
MESH:D003711 Demyelinating Diseases Tamoxifen 4.8519031437
MESH:D003928 Diabetic Nephropathies Tamoxifen 3.8019279558
MESH:D004489 Edema, Cardiac Tretinoin 5.0818230668
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Tamoxifen 3.9819031437
MESH:D016889 Endometrial Neoplasms Tamoxifen 8.1716202921 19155303 20544844 17893378
MESH:D016889 Endometrial Neoplasms Tretinoin 8.1716569247
MESH:D004938 Esophageal Neoplasms Benzo(a)pyrene 2.0716530937
MESH:D005124 Eye Abnormalities Tretinoin 3.8416938888 9664655
MESH:D005234 Fatty Liver Cyclosporine 8.9719224547
MESH:D005234 Fatty Liver Tamoxifen 8.9714986274 19224547
MESH:D052776 Female Urogenital Diseases Tamoxifen 3.4316709447
MESH:D018221 Fibromatosis, Abdominal Tamoxifen 5.0714745880
MESH:D018222 Fibromatosis, Aggressive Tamoxifen 4.7219069698
MESH:D005355 Fibrosis Cyclosporine 10.3512639820 12168785
MESH:D005355 Fibrosis Tretinoin 10.3517994277
MESH:D005885 Gingival Hyperplasia Cyclosporine 4.768708960
MESH:D005909 Glioblastoma Tretinoin 3.2217312396
MESH:D006258 Head and Neck Neoplasms Tretinoin 3.4116096774
MESH:D006317 Hearing Loss, Noise-Induced Tretinoin 5.7716084493
MESH:D006330 Heart Defects, Congenital Benzo(a)pyrene 7.2020471113
MESH:D006330 Heart Defects, Congenital Tretinoin 7.209664655 14991402
MESH:D006457 Hemoglobinuria, Paroxysmal Cyclosporine 4.9615720958
MESH:D006930 Hyperalgesia Tretinoin 3.5016870215
MESH:D017681 Hypereosinophilic Syndrome Tretinoin 5.0516778211
MESH:D006973 Hypertension Cyclosporine 2.2010903974
MESH:D007249 Inflammation Tamoxifen 2.5119457130
MESH:D007410 Intestinal Diseases Tretinoin 4.2517994277
MESH:D007569 Jaw Abnormalities Tretinoin 4.2717551590 15992940
MESH:D007638 Keratoconjunctivitis Sicca Cyclosporine 5.0515604871
MESH:D007674 Kidney Diseases Cyclosporine 2.528314463 18776723 10903974
MESH:D007680 Kidney Neoplasms Cyclosporine 8.3312371664
MESH:D007680 Kidney Neoplasms Tamoxifen 8.3318625569
MESH:D007938 Leukemia Tretinoin 2.9217143497
MESH:D007951 Leukemia, Myeloid Tretinoin 4.0716482212 19285840 16932348
MESH:D015470 Leukemia, Myeloid, Acute Tretinoin 2.1216294345 17596541 19850784
MESH:D015473 Leukemia, Promyelocytic, Acute Tretinoin 3.3717712046 16140955 17649720 12679006 19642359 16331271 19035177 17368321 17294898 16766008 16823087 15748426 17339181 9834237 16788101 17506722 17107899 17217047 19075265 19029980 16935935 17301526 19225113 17361223 16891316
MESH:D017880 Limb Deformities, Congenital Tretinoin 3.559224671
MESH:D008064 Lipidoses Tamoxifen 3.4017567588 15342952
MESH:D008106 Liver Cirrhosis, Experimental Tamoxifen 2.5718564211
MESH:D008106 Liver Cirrhosis, Experimental Tretinoin 2.5718397230 16248980
MESH:D008113 Liver Neoplasms Aflatoxin B1 8.102125692 15890375 18177683 9163691
MESH:D008113 Liver Neoplasms Benzo(a)pyrene 8.1020195826 21137059
MESH:D008113 Liver Neoplasms Tamoxifen 8.1016684651
MESH:D008114 Liver Neoplasms, Experimental Aflatoxin B1 2.948603461
MESH:D008175 Lung Neoplasms Aflatoxin B1 3.6014755239
MESH:D008175 Lung Neoplasms Benzo(a)pyrene 3.6020464547 17053015 18569708 18520028 20135361 20869020 18816296 20064080 6695378
MESH:D008175 Lung Neoplasms Tamoxifen 3.6018625569
MESH:D015674 Mammary Neoplasms, Animal Tamoxifen 4.3019428831
MESH:D008325 Mammary Neoplasms, Experimental Tamoxifen 2.8311731420 19196722 14580682 16827153 19196723
MESH:D020149 Manganese Poisoning Tamoxifen 5.1619453300
MESH:D008527 Medulloblastoma Tretinoin 2.9017453147
MESH:D008545 Melanoma Tamoxifen 3.4419393235 12393984
MESH:D008545 Melanoma Tretinoin 3.4416752155
MESH:D018328 Melanoma, Amelanotic Tamoxifen 4.7215990972
MESH:D008591 Meningomyelocele Tretinoin 4.9116940565
MESH:D008664 Metal Metabolism, Inborn Errors Cyclosporine 5.4016801185
MESH:D009062 Mouth Neoplasms Benzo(a)pyrene 3.4616381670
MESH:D009190 Myelodysplastic Syndromes Tretinoin 3.2617596541
MESH:D009362 Neoplasm Metastasis Tamoxifen 2.6619393235
MESH:D009364 Neoplasm Recurrence, Local Tamoxifen 2.6019410462
MESH:D009369 Neoplasms Benzo(a)pyrene 5.5011141357
MESH:D009369 Neoplasms Tretinoin 5.5016946489 16594593
MESH:D009376 Neoplasms, Hormone-Dependent Tamoxifen 4.6119189210 19200415 19196722
MESH:D009402 Nephrosis, Lipoid Cyclosporine 5.0517954296
MESH:D009404 Nephrotic Syndrome Cyclosporine 3.6118481113 19348381
MESH:D009421 Nervous System Malformations Tretinoin 4.229125849
MESH:D009436 Neural Tube Defects Tretinoin 3.279142499
MESH:D010051 Ovarian Neoplasms Tretinoin 2.4316936753
MESH:D010146 Pain Tretinoin 3.2016870215
MESH:D010190 Pancreatic Neoplasms Tretinoin 2.5615976015
MESH:D011230 Precancerous Conditions Cyclosporine 3.5512371664
MESH:D011471 Prostatic Neoplasms Benzo(a)pyrene 3.0617292933
MESH:D011471 Prostatic Neoplasms Tamoxifen 3.0615067354
MESH:D011507 Proteinuria Tretinoin 4.0116636307
MESH:D011565 Psoriasis Cyclosporine 2.3216882103
MESH:D011625 Pterygium Tretinoin 5.3316723453
MESH:D012208 Rhabdomyosarcoma Tretinoin 4.5016283617 16116481
MESH:D012878 Skin Neoplasms Benzo(a)pyrene 6.1619755658 10029692
MESH:D012878 Skin Neoplasms Tretinoin 6.1616467112
MESH:D013088 Spermatocele Tamoxifen 4.9016709447
MESH:D013119 Spinal Cord Injuries Tamoxifen 4.5819457130
MESH:D013274 Stomach Neoplasms Benzo(a)pyrene 2.412093021 20155912
MESH:D013274 Stomach Neoplasms Tretinoin 2.4117261132
MESH:D013964 Thyroid Neoplasms Tretinoin 3.2917045167 16026305
MESH:D014062 Tongue Neoplasms Tretinoin 4.1416051514
MESH:D014376 Tuberculosis Tretinoin 3.4316040207
MESH:D001749 Urinary Bladder Neoplasms Benzo(a)pyrene 5.3817053015
MESH:D001749 Urinary Bladder Neoplasms Tamoxifen 5.388653321 16712894 17572228
MESH:D002583 Uterine Cervical Neoplasms Tretinoin 4.0216129372
MESH:D014604 Uveal Neoplasms Tretinoin 5.2216752155
MESH:D014605 Uveitis Cyclosporine 4.591336536
MESH:D014820 Vitiligo Tretinoin 4.5016761959
MESH:D009396 Wilms Tumor Tretinoin 4.2916287080
MESH:D014985 Xerophthalmia Cyclosporine 5.0517120751
No data
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Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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