AutismKB 2.0

Annotation Detail for PRIM2


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:PRIM2 ( MGC75142,PRIM2A,p58 )
Gene Full Name: primase, DNA, polypeptide 2 (58kDa)
Band: 6p11.2
Quick LinksEntrez ID:5558; OMIM: 176636; Uniprot ID:PRI2_HUMAN; ENSEMBL ID: ENSG00000146143; HGNC ID: 9370
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
No data
Pathway IDPathway Name
hsa00240Pyrimidine metabolism
hsa03030DNA replication
hsa00230Purine metabolism
hsa01100Metabolic pathways
Pathway IDPathway Name
Cell Cycle, Mitotic
DNA Replication
Chromosome Maintenance
No data
Pathway IDPathway Name
P00017DNA replication
No data
Related Diseases/Disorders Top
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C009505 4,4'-diaminodiphenylmethane 4,4'-diaminodiphenylmethane results in increased expression of PRIM2 mRNAincreases expression 18648102
D000082 Acetaminophen Acetaminophen results in decreased expression of PRIM2 mRNAdecreases expression 17942131
D000638 Amiodarone Amiodarone results in increased expression of PRIM2 mRNAincreases expression 19774075
D000643 Ammonium Chloride Ammonium Chloride affects the expression of PRIM2 mRNAaffects expression 16483693
D001564 Benzo(a)pyrene Benzo(a)pyrene results in decreased expression of PRIM2 mRNAdecreases expression 20106945
20064835
D001564 Benzo(a)pyrene Benzo(a)pyrene results in decreased expression of PRIM2 mRNAdecreases expression 17942131
20504355
D015123 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in decreased expression of PRIM2 mRNAdecreases expression 20382639
C005961 bis(tri-n-butyltin)oxide bis(tri-n-butyltin)oxide results in decreased expression of PRIM2 mRNAdecreases expression 17942131
D002251 Carbon Tetrachloride Carbon Tetrachloride affects the expression of PRIM2 mRNAaffects expression 12734012
D016572 Cyclosporine Cyclosporine results in decreased expression of PRIM2 mRNAdecreases expression 20106945
D016572 Cyclosporine Cyclosporine results in decreased expression of PRIM2 mRNAdecreases expression 17942131
D004041 Dietary Fats Dietary Fats results in increased expression of PRIM2 mRNAincreases expression 18503570
C007610 equol equol results in decreased expression of PRIM2 mRNAdecreases expression 16865672
D004997 Ethinyl Estradiol [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in decreased expression of PRIM2 mRNAaffects cotreatment|decreases expression 17942748
D008345 Manganese Manganese results in decreased expression of PRIM2 mRNAdecreases expression 17175027
C025340 manganese chloride manganese chloride results in decreased expression of PRIM2 mRNAdecreases expression 17175027
D026023 Permethrin Permethrin results in increased expression of PRIM2 mRNAincreases expression 19017407
D013749 Tetrachlorodibenzodioxin [Tetrachlorodibenzodioxin co-treated with AHR gene mutant form] results in decreased expression of PRIM2 mRNAaffects cotreatment|decreases expression 19465110
D013749 Tetrachlorodibenzodioxin [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in decreased expression of PRIM2 mRNAaffects cotreatment|decreases expression 17942748
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in increased expression of PRIM2 mRNAincreases expression 20159946
15667827
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000014 Abnormalities, Drug-Induced Tetrachlorodibenzodioxin 2.8715322242 11752688 14514962
MESH:D000138 Acidosis Ammonium Chloride 3.5818287403
MESH:D000152 Acne Vulgaris Ethinyl Estradiol 3.9717505938
MESH:D000230 Adenocarcinoma Benzo(a)pyrene 4.1820127859 20464547
MESH:D000230 Adenocarcinoma Ethinyl Estradiol 4.1814692618
MESH:D000236 Adenoma 4,4'-diaminodiphenylmethane 6.603712494
MESH:D000236 Adenoma Benzo(a)pyrene 6.606695378
MESH:D018248 Adenoma, Liver Cell Tetrachlorodibenzodioxin 3.4016835633
MESH:D000740 Anemia Tetrachlorodibenzodioxin 2.9511748828
MESH:D000756 Anemia, Sideroblastic Manganese 11.0516910769
MESH:D000756 Anemia, Sideroblastic manganese chloride 11.0516910769
MESH:D000799 Angioedema Acetaminophen 3.8710982225
MESH:D017544 Aortic Aneurysm, Abdominal Benzo(a)pyrene 4.0919183758
MESH:D001145 Arrhythmias, Cardiac Amiodarone 3.8020041841 18057881 18218290
MESH:D001161 Arteriosclerosis Dietary Fats 9.9515238619
MESH:D001161 Arteriosclerosis Ethinyl Estradiol 9.9511256880
MESH:D001169 Arthritis, Experimental Ethinyl Estradiol 2.6615885639
MESH:D001281 Atrial Fibrillation Amiodarone 3.9019698954 18651412
MESH:D001321 Autistic Disorder Acetaminophen 1.4218445737
MESH:D001660 Biliary Tract Diseases 4,4'-diaminodiphenylmethane 5.0511289319 1440618
MESH:D001778 Blood Coagulation Disorders Amiodarone 9.0619483382
MESH:D001778 Blood Coagulation Disorders Tetrachlorodibenzodioxin 9.0612125929
MESH:D001836 Body Weight Changes Tetrachlorodibenzodioxin 3.8215340226
MESH:D001848 Bone Diseases, Developmental Tetrachlorodibenzodioxin 2.7615746008
MESH:D001943 Breast Neoplasms Benzo(a)pyrene 2.0117474063 20146248
MESH:D001943 Breast Neoplasms Dietary Fats 2.0120435547
MESH:D001943 Breast Neoplasms equol 2.0116898868
MESH:D001943 Breast Neoplasms Tetrachlorodibenzodioxin 2.0120435547
MESH:D002252 Carbon Tetrachloride Poisoning Carbon Tetrachloride 3.7910355542 16050911 16011737 15721981 18705752 15700767 16124888 15673190 16097048 16227642 3786805 16192424
MESH:D002277 Carcinoma Tetrachlorodibenzodioxin 2.8016835633
MESH:D006528 Carcinoma, Hepatocellular 4,4'-diaminodiphenylmethane 4.523581430 7296757
MESH:D006528 Carcinoma, Hepatocellular Acetaminophen 4.523084413
MESH:D006528 Carcinoma, Hepatocellular Carbon Tetrachloride 4.5218788625
MESH:D002292 Carcinoma, Renal Cell 4,4'-diaminodiphenylmethane 2.687296757
MESH:D002294 Carcinoma, Squamous Cell Benzo(a)pyrene 2.0520419170
MESH:D006332 Cardiomegaly Tetrachlorodibenzodioxin 2.3716120746 18670907 18850075
MESH:D002311 Cardiomyopathy, Dilated Amiodarone 2.8915710769 19225199
MESH:D002341 Carotid Artery Thrombosis Amiodarone 5.1018974383
MESH:D002386 Cataract Acetaminophen 2.5810977129
MESH:D002471 Cell Transformation, Neoplastic 4,4'-diaminodiphenylmethane 11.157505956
MESH:D002471 Cell Transformation, Neoplastic 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 11.1520889678
MESH:D002471 Cell Transformation, Neoplastic Cyclosporine 11.1512371664
MESH:D018281 Cholangiocarcinoma Tetrachlorodibenzodioxin 3.1616835633
MESH:D002779 Cholestasis 4,4'-diaminodiphenylmethane 13.4019486331 9022650
MESH:D002779 Cholestasis Cyclosporine 13.4019486331
MESH:D002779 Cholestasis Ethinyl Estradiol 13.4016919318 15861022 16105132 17333356 17681005 11677210 17110522
MESH:D002972 Cleft Palate Tetrachlorodibenzodioxin 2.1016354765 12621046 8697196 15668235 15340226
MESH:D000013 Congenital Abnormalities Tetrachlorodibenzodioxin 3.0617141729 14669216
MESH:D019465 Craniofacial Abnormalities Permethrin 2.9519861644
MESH:D019465 Craniofacial Abnormalities Tetrachlorodibenzodioxin 2.9520055451 10048152 15322242
MESH:D017449 Dermatitis, Allergic Contact 4,4'-diaminodiphenylmethane 2.828970840 8156756 12868966 2524372 11298694 14531868 18759878 11906362
MESH:D003877 Dermatitis, Contact 4,4'-diaminodiphenylmethane 9.692952479 3621924
MESH:D003877 Dermatitis, Contact Permethrin 9.6914617103
MESH:D003924 Diabetes Mellitus, Type 2 Tetrachlorodibenzodioxin 1.6717107852
MESH:D056486 Drug-Induced Liver Injury 4,4'-diaminodiphenylmethane 12.021440618 9653073 11289319 18692083 18648102 8291058 6482804 18289764 16192314 9022650 7440962 6679447 9328219
MESH:D056486 Drug-Induced Liver Injury Acetaminophen 12.0219923254 12958197 19420014 10915739 12153990 16081117 10774834 14986274 14550746 19416960 12594235 16781746 17562736 19739265 10663392 11287661 19164858 11461765 19370779 11739529 15968718 12705907 16485898 14725611 2444490 18713872 15619225 16227642 11529661 16109766 16393943 19085960 12540782 17906064 12392966 11834606 11421492 11743745 17522070 16177239 18071297
MESH:D056486 Drug-Induced Liver Injury Amiodarone 12.0218218290 15265979
MESH:D056486 Drug-Induced Liver Injury Carbon Tetrachloride 12.0216227642 15027814 19336974 6884620 11566570 7120509 7440962 6623471 2869522 3786805 15968718 10092053 19085960 15998439 4309450 21278145 16177239 3732212 10915739 7179309 9327722 17522070
MESH:D056486 Drug-Induced Liver Injury Tetrachlorodibenzodioxin 12.0220420201
MESH:D056487 Drug-Induced Liver Injury, Chronic Acetaminophen 4.1319426721
MESH:D004362 Drug Toxicity Tetrachlorodibenzodioxin 2.7611462148
MESH:D050171 Dyslipidemias Dietary Fats 3.4518367378
MESH:D004487 Edema Tetrachlorodibenzodioxin 2.3811000095 12711302
MESH:D004489 Edema, Cardiac Tetrachlorodibenzodioxin 3.9318230668 15322242 16714409
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Ethinyl Estradiol 3.2012538720
MESH:D004715 Endometriosis Tetrachlorodibenzodioxin 3.0210568697 9294722
MESH:D004938 Esophageal Neoplasms 4,4'-diaminodiphenylmethane 7.193581430
MESH:D004938 Esophageal Neoplasms 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 7.1920426865
MESH:D004938 Esophageal Neoplasms Benzo(a)pyrene 7.1916530937
MESH:D005124 Eye Abnormalities Tetrachlorodibenzodioxin 3.0111564622
MESH:D005234 Fatty Liver Amiodarone 24.7314986274
MESH:D005234 Fatty Liver Carbon Tetrachloride 24.7312795759 16239168 16045604 15959796 19224547 61145 12631006 17595544
MESH:D005234 Fatty Liver Cyclosporine 24.7319224547
MESH:D005234 Fatty Liver Dietary Fats 24.7318296743 17967931 19551842 19004024
MESH:D005234 Fatty Liver Ethinyl Estradiol 24.7315345470
MESH:D005313 Fetal Death Tetrachlorodibenzodioxin 3.4711858732
MESH:D005350 Fibroma 4,4'-diaminodiphenylmethane 5.056705139
MESH:D005355 Fibrosis Carbon Tetrachloride 21.2718705752
MESH:D005355 Fibrosis Cyclosporine 21.2712168785 12639820
MESH:D005355 Fibrosis Dietary Fats 21.2718296743
MESH:D005355 Fibrosis Tetrachlorodibenzodioxin 21.2720067830
MESH:D005756 Gastritis Acetaminophen 3.7116983495
MESH:D005885 Gingival Hyperplasia Cyclosporine 4.248708960
MESH:D005909 Glioblastoma Manganese 3.9217043766
MESH:D006042 Goiter 4,4'-diaminodiphenylmethane 4.047505956
MESH:D006058 Gonadal Disorders Tetrachlorodibenzodioxin 4.6210696789
MESH:D006330 Heart Defects, Congenital Benzo(a)pyrene 6.4520471113
MESH:D006330 Heart Defects, Congenital Tetrachlorodibenzodioxin 6.4511294989 10048152
MESH:D006457 Hemoglobinuria, Paroxysmal Cyclosporine 4.4415720958
MESH:D006470 Hemorrhage Tetrachlorodibenzodioxin 3.3411000095
MESH:D006505 Hepatitis 4,4'-diaminodiphenylmethane 9.266705139
MESH:D006505 Hepatitis Carbon Tetrachloride 9.2619900420 19110552
MESH:D006529 Hepatomegaly Amiodarone 8.5815265979
MESH:D006529 Hepatomegaly Tetrachlorodibenzodioxin 8.5816120746 15340226 12621046
MESH:D006869 Hydronephrosis Tetrachlorodibenzodioxin 4.088697196 18606429 15340226 16959395 16354765
MESH:D006930 Hyperalgesia Acetaminophen 2.7016870215
MESH:D006932 Hyperbilirubinemia Carbon Tetrachloride 4.5516899240
MESH:D006937 Hypercholesterolemia Amiodarone 9.188137927 9751232
MESH:D006937 Hypercholesterolemia Dietary Fats 9.1821332399
MESH:D006949 Hyperlipidemias Dietary Fats 3.6221332399
MESH:D006965 Hyperplasia 4,4'-diaminodiphenylmethane 3.9515034207
MESH:D006973 Hypertension Cyclosporine 4.9510903974
MESH:D006973 Hypertension Tetrachlorodibenzodioxin 4.9518670907 18850075
MESH:D006975 Hypertension, Portal Carbon Tetrachloride 4.1015338365
MESH:D007021 Hypospadias Ethinyl Estradiol 3.8216945680 16569931
MESH:D007037 Hypothyroidism Amiodarone 4.5317991464 18020914
MESH:D007247 Infertility, Female Ethinyl Estradiol 3.4712013081
MESH:D007248 Infertility, Male Ethinyl Estradiol 2.4917937319
MESH:D007249 Inflammation Dietary Fats 4.9220412841
MESH:D007249 Inflammation Tetrachlorodibenzodioxin 4.9212200463 12878042
MESH:D007299 Insect Bites and Stings Permethrin 5.8612749493 15189238 12971516
MESH:D007333 Insulin Resistance Dietary Fats 3.1118457598 11836018
MESH:D007565 Jaundice 4,4'-diaminodiphenylmethane 5.059022650 8074119
MESH:D007569 Jaw Abnormalities Tetrachlorodibenzodioxin 3.3416580747
MESH:D007638 Keratoconjunctivitis Sicca Cyclosporine 4.4715604871
MESH:D007674 Kidney Diseases Acetaminophen 5.8015629191 12587719
MESH:D007674 Kidney Diseases Cyclosporine 5.8018776723 8314463 10903974
MESH:D007680 Kidney Neoplasms 4,4'-diaminodiphenylmethane 7.286582329
MESH:D007680 Kidney Neoplasms Cyclosporine 7.2812371664
MESH:D007938 Leukemia Permethrin 4.1312937054
MESH:D008064 Lipidoses Amiodarone 3.5117567588 15342952
MESH:D008103 Liver Cirrhosis Carbon Tetrachloride 6.6316221502 11408273 11903743 17174718 17157831 21278145 16239168 16943688 17334410
MESH:D008103 Liver Cirrhosis Dietary Fats 6.6318296743
MESH:D008105 Liver Cirrhosis, Biliary 4,4'-diaminodiphenylmethane 3.209327722 15034207
MESH:D008106 Liver Cirrhosis, Experimental Carbon Tetrachloride 2.2812666154 18395914 17698563 17721639 17976157 16248980 16011737 12958196 15650968 15996030 15818738 16027843 14716496 18429990 18263696 15057751 17869086 18705752 16136751 11481614 15959796 14716833 14512876 18156304 17761835 16116963 15931870 17805973 18472332 17631135 18251166 15673190 18472094 16192424 12649538 12632512 17708605 17944888 12445418 18210741 17823541 18317297 15925388 20821823 14620537 12546737 16015684 18187930 17922224 17525996 14748882 18339082 18277467 18205269 12389079 15362042 15893842 12667390 15052691 17766677 18054572 16033810 15370692 15123356 17714472 18412020 18376398 18166357 18006644 18395095 16638106 18481824 17481882 15876570 12609069 13678700 12741479 12445421 15338365 14724832 17900296 18279442 17640975 12586293 16097048 18420326 12898905 17557913 18418968 15730626 17565644 12632514 10355542
MESH:D008106 Liver Cirrhosis, Experimental Tetrachlorodibenzodioxin 2.2812878042
MESH:D008107 Liver Diseases Acetaminophen 3.9019014921 16611625 11587558 16610002 12969438 19460945 19784758 12587719
MESH:D008107 Liver Diseases Carbon Tetrachloride 3.9015830285 17285989 16246199 15720792 16964402
MESH:D017093 Liver Failure Carbon Tetrachloride 4.1815123358
MESH:D017114 Liver Failure, Acute Acetaminophen 9.4217185352 16871587
MESH:D017114 Liver Failure, Acute Carbon Tetrachloride 9.4216899240 14706259
MESH:D008113 Liver Neoplasms Benzo(a)pyrene 7.3721137059 20195826
MESH:D008113 Liver Neoplasms Carbon Tetrachloride 7.3719294768
MESH:D008113 Liver Neoplasms Tetrachlorodibenzodioxin 7.3716984957
MESH:D008114 Liver Neoplasms, Experimental 4,4'-diaminodiphenylmethane 9.796587162 598648 3712494 1399818
MESH:D008114 Liver Neoplasms, Experimental Carbon Tetrachloride 9.7912014681 15583823
MESH:D008114 Liver Neoplasms, Experimental Tetrachlorodibenzodioxin 9.7912151625
MESH:D008133 Long QT Syndrome Amiodarone 3.5817391786 11989578 15350150
MESH:D008171 Lung Diseases Amiodarone 3.3712587719
MESH:D017563 Lung Diseases, Interstitial Amiodarone 4.5118516814
MESH:D008175 Lung Neoplasms Benzo(a)pyrene 2.1820064080 20135361 17053015 18816296 20869020 20464547 18520028 18569708 6695378
MESH:D008175 Lung Neoplasms Tetrachlorodibenzodioxin 2.1811884234 19555203
MESH:D020149 Manganese Poisoning Manganese 5.5519453300 16568477 16551646
MESH:D008546 Melanoma, Experimental Acetaminophen 3.5819513568
MESH:D008664 Metal Metabolism, Inborn Errors Cyclosporine 4.8216801185
MESH:D009062 Mouth Neoplasms Benzo(a)pyrene 3.1916381670
MESH:D009069 Movement Disorders Manganese 5.0216551646
MESH:D009181 Mycoses Amiodarone 4.9312754197 17974566
MESH:D017202 Myocardial Ischemia Tetrachlorodibenzodioxin 3.0212213967
MESH:D009362 Neoplasm Metastasis 4,4'-diaminodiphenylmethane 2.473581430
MESH:D009369 Neoplasms Benzo(a)pyrene 2.1711141357
MESH:D009402 Nephrosis, Lipoid Cyclosporine 4.4717954296
MESH:D009404 Nephrotic Syndrome Cyclosporine 3.2919348381 18481113
MESH:D009410 Nerve Degeneration Manganese 4.2716551646
MESH:D009421 Nervous System Malformations Tetrachlorodibenzodioxin 3.2214600291
MESH:D009436 Neural Tube Defects 4,4'-diaminodiphenylmethane 2.916679447
MESH:D019636 Neurodegenerative Diseases Acetaminophen 2.8718514411
MESH:D009765 Obesity Dietary Fats 2.2916723640 21332399 20132043 19632207 20518802 11836018 18457598 18674790 17217161
MESH:D009784 Occupational Diseases 4,4'-diaminodiphenylmethane 3.424026338 6482804
MESH:D009902 Optic Neuritis 4,4'-diaminodiphenylmethane 5.053988306
MESH:D010146 Pain Acetaminophen 2.3916870215
MESH:D016584 Panic Disorder Ethinyl Estradiol 3.6911578682
MESH:D010212 Papilloma 4,4'-diaminodiphenylmethane 3.507296757
MESH:D010300 Parkinson Disease Manganese 3.3711181820
MESH:D020734 Parkinsonian Disorders Manganese 4.4716140633
MESH:D010382 Peliosis Hepatis Tetrachlorodibenzodioxin 4.2812520081
MESH:D010787 Photosensitivity Disorders 4,4'-diaminodiphenylmethane 4.506228378
MESH:D017119 Porphyria Cutanea Tarda Tetrachlorodibenzodioxin 3.5718163543
MESH:D011230 Precancerous Conditions Cyclosporine 3.2212371664
MESH:D011297 Prenatal Exposure Delayed Effects Tetrachlorodibenzodioxin 3.2111118676 11896295 11222880 11399792
MESH:D011471 Prostatic Neoplasms Benzo(a)pyrene 3.7917292933
MESH:D011471 Prostatic Neoplasms equol 3.7916925846 16898868
MESH:D011537 Pruritus Ethinyl Estradiol 3.3316919318 15861022
MESH:D011565 Psoriasis Cyclosporine 2.2316882103
MESH:D011658 Pulmonary Fibrosis Amiodarone 2.8511597910 12490602 12832656
MESH:D015619 Respiratory System Abnormalities Tetrachlorodibenzodioxin 3.8518990726
MESH:D012162 Retinal Degeneration 4,4'-diaminodiphenylmethane 3.383692021
OMIM:609620 SHORT QT SYNDROME 1 Amiodarone 5.1018724381
MESH:D012878 Skin Neoplasms Benzo(a)pyrene 5.4810029692 19755658
MESH:D012878 Skin Neoplasms Tetrachlorodibenzodioxin 5.4816192470
MESH:D013088 Spermatocele Ethinyl Estradiol 3.9716709447
MESH:D013274 Stomach Neoplasms Benzo(a)pyrene 1.562093021 20155912
MESH:D013276 Stomach Ulcer Amiodarone 3.3218087811
MESH:D013610 Tachycardia Amiodarone 4.3011238279
MESH:D017180 Tachycardia, Ventricular Amiodarone 4.2019225199
MESH:D019851 Thrombophilia Ethinyl Estradiol 3.6311994571
MESH:D013927 Thrombosis Ethinyl Estradiol 3.1515669648
MESH:D013959 Thyroid Diseases Amiodarone 12.1519731979
MESH:D013959 Thyroid Diseases Tetrachlorodibenzodioxin 12.1512697716
MESH:D013964 Thyroid Neoplasms 4,4'-diaminodiphenylmethane 2.891399818 6587162 7505956 6582329 3712494
MESH:D013971 Thyrotoxicosis Amiodarone 4.8719584973 18020914
MESH:D016171 Torsades de Pointes Amiodarone 4.2111989578 17467628
MESH:D001749 Urinary Bladder Neoplasms 4,4'-diaminodiphenylmethane 4.978074119
MESH:D001749 Urinary Bladder Neoplasms Benzo(a)pyrene 4.9717053015
MESH:D014581 Urticaria Acetaminophen 2.9810982225
MESH:D014594 Uterine Neoplasms Ethinyl Estradiol 3.3114692618
MESH:D014605 Uveitis Cyclosporine 4.011336536
MESH:D054079 Vascular Malformations Tetrachlorodibenzodioxin 4.6212125929
MESH:D020246 Venous Thrombosis Ethinyl Estradiol 3.5414671159 15869587
MESH:D019282 Wasting Syndrome Tetrachlorodibenzodioxin 4.2815886252
MESH:D015430 Weight Gain Dietary Fats 3.7416723640
MESH:D014985 Xerophthalmia Cyclosporine 4.4717120751
Pathway ID Pathway Name
REACT:152 Cell Cycle, Mitotic
REACT:22172 Chromosome Maintenance
KEGG:03030 DNA replication
REACT:383 DNA Replication
KEGG:01100 Metabolic pathways
KEGG:00230 Purine metabolism
KEGG:00240 Pyrimidine metabolism
Pharmacogenomics Knowledge Base Top
  • PharmGKB Accession:PA162400108
    • No data
    Releated disease ID Related disease Name
    PA446155Precursor Cell Lymphoblastic Leukemia-Lymphoma
    No data
    Drug Bank Top

    Simple Query:


      (e.g. CHD8)

    Syndromic Genes

    Non-syndromic Genes

    AutismKB Statistics

    • Studies: 1,036
    • Genes: 1,379
    • CNVs/SVs: 5,420
    • SNVs/Indels: 11,669
    • de novo Mutations: 5,669
    • Mosaics: 789
    • Linkage Regions: 172
    • Paper Collected: 6/30/2018
    • Last Update: 8/26/2018


    Copyright © 2017, Center for Bioinformatics , Peking University | All Rights Reserved