AutismKB 2.0

Annotation Detail for TTC27


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Basic Information Top
Gene Symbol:TTC27 ( FLJ20272 )
Gene Full Name: tetratricopeptide repeat domain 27
Band: 2p22.3
Quick LinksEntrez ID:55622; OMIM: NA; Uniprot ID:TTC27_HUMAN; ENSEMBL ID: ENSG00000018699; HGNC ID: 25986
Relate to Another Database: SFARIGene; denovo-db
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Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
D001564 Benzo(a)pyrene Benzo(a)pyrene results in decreased expression of TTC27 mRNAdecreases expression 20064835
20106945
D015123 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in decreased expression of TTC27 mRNAdecreases expression 20382639
D018038 Sodium Selenite Sodium Selenite results in increased expression of TTC27 mRNAincreases expression 18175754
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000230 Adenocarcinoma Benzo(a)pyrene 2.0620127859 20464547
MESH:D000236 Adenoma Benzo(a)pyrene 2.886695378
MESH:D017544 Aortic Aneurysm, Abdominal Benzo(a)pyrene 4.7319183758
MESH:D001943 Breast Neoplasms Benzo(a)pyrene 1.9917474063 20146248
MESH:D002294 Carcinoma, Squamous Cell Benzo(a)pyrene 2.1420419170
MESH:D002471 Cell Transformation, Neoplastic 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 3.0120889678
MESH:D019457 Chromosome Breakage Sodium Selenite 5.4115894690
MESH:D003920 Diabetes Mellitus Sodium Selenite 4.1916285004
MESH:D056486 Drug-Induced Liver Injury Sodium Selenite 2.3715131321
MESH:D004938 Esophageal Neoplasms 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 4.6420426865
MESH:D004938 Esophageal Neoplasms Benzo(a)pyrene 4.6416530937
MESH:D006330 Heart Defects, Congenital Benzo(a)pyrene 2.8520471113
MESH:D007333 Insulin Resistance Sodium Selenite 3.5414714311
MESH:D008113 Liver Neoplasms Benzo(a)pyrene 2.1720195826 21137059
MESH:D008175 Lung Neoplasms Benzo(a)pyrene 1.5720464547 18520028 18816296 17053015 6695378 18569708 20064080 20869020 20135361
MESH:D016393 Lymphoma, B-Cell Sodium Selenite 4.5914737004
MESH:D009062 Mouth Neoplasms Benzo(a)pyrene 3.5316381670
MESH:D009369 Neoplasms Benzo(a)pyrene 2.3511141357
MESH:D011471 Prostatic Neoplasms Benzo(a)pyrene 3.1317292933
MESH:D011471 Prostatic Neoplasms Sodium Selenite 3.1318760546
MESH:D012878 Skin Neoplasms Benzo(a)pyrene 2.5410029692 19755658
MESH:D013274 Stomach Neoplasms Benzo(a)pyrene 1.562093021 20155912
MESH:D001749 Urinary Bladder Neoplasms Benzo(a)pyrene 2.3117053015
No data
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Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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