Annotation Detail for BTBD2
Basic Information
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| Chemical ID |
Chemical Name |
Interaction |
Interaction Action |
Publication |
|---|
| C006632 |
arsenic trioxide |
arsenic trioxide results in decreased expression of BTBD2 mRNA | decreases expression | 15725085
|
| D020122 |
tert-Butylhydroperoxide |
tert-Butylhydroperoxide results in decreased expression of BTBD2 mRNA | decreases expression | 15336504
|
| D015032 |
Zinc |
Zinc affects the expression of BTBD2 mRNA | affects expression | 16979875
|
| Disease ID |
Disease Name |
Direct Evidence |
Inference Chemical Name |
Inference Score |
Publication |
|---|
| MESH:D000169 |
Acrodermatitis |
|
Zinc |
6.15 | 17202136 17190629 16889938 |
| MESH:D000230 |
Adenocarcinoma |
|
arsenic trioxide |
2.36 | 11798837 19825857 |
| MESH:D000544 |
Alzheimer Disease |
|
Zinc |
2.82 | 17119284 16325427 16580781 16410023 |
| MESH:D000755 |
Anemia, Sickle Cell |
|
Zinc |
5.49 | 16916123 |
| MESH:D001249 |
Asthma |
|
Zinc |
3.05 | 17085522 |
| MESH:D001778 |
Blood Coagulation Disorders |
|
arsenic trioxide |
4.15 | 16206674 |
| MESH:D001930 |
Brain Injuries |
|
Zinc |
5.34 | 17109824 |
| MESH:D002051 |
Burkitt Lymphoma |
|
arsenic trioxide |
4.86 | 11589617 |
| MESH:D006528 |
Carcinoma, Hepatocellular |
|
arsenic trioxide |
1.98 | 14691202 16217749 15073043 15553829 11135700 |
| MESH:D002291 |
Carcinoma, Papillary |
|
arsenic trioxide |
5.74 | 19014326 |
| MESH:D018288 |
Carcinoma, Small Cell |
|
arsenic trioxide |
4.57 | 12490120 |
| MESH:D002294 |
Carcinoma, Squamous Cell |
|
Zinc |
2.99 | 16543248 |
| MESH:D002318 |
Cardiovascular Diseases |
|
Zinc |
3.95 | 16936243 |
| MESH:D015179 |
Colorectal Neoplasms |
|
arsenic trioxide |
1.87 | 20501625 |
| MESH:D023903 |
Coronary Restenosis |
|
arsenic trioxide |
4.77 | 12609071 |
| MESH:D019465 |
Craniofacial Abnormalities |
|
arsenic trioxide |
3.00 | 10525206 |
| MESH:D019465 |
Craniofacial Abnormalities |
|
Zinc |
3.00 | 19302082 |
| MESH:D016757 |
Death, Sudden, Cardiac |
|
arsenic trioxide |
4.63 | 15213294 |
| MESH:D003920 |
Diabetes Mellitus |
|
Zinc |
4.62 | 16479319 |
| MESH:D004938 |
Esophageal Neoplasms |
|
arsenic trioxide |
5.04 | 12903497 |
| MESH:D004938 |
Esophageal Neoplasms |
|
Zinc |
5.04 | 16543248 |
| MESH:D005234 |
Fatty Liver |
|
arsenic trioxide |
3.77 | 15073043 |
| MESH:D005706 |
Gallbladder Neoplasms |
|
arsenic trioxide |
4.85 | 16904648 |
| MESH:D005756 |
Gastritis |
|
Zinc |
5.66 | 17241300 |
| MESH:D006130 |
Growth Disorders |
|
Zinc |
4.22 | 17217573 |
| MESH:D006333 |
Heart Failure |
|
Zinc |
3.85 | 17162251 |
| MESH:D006335 |
Heart Injuries |
|
Zinc |
6.64 | 17074742 |
| MESH:D016481 |
Helicobacter Infections |
|
Zinc |
5.06 | 17241300 |
| MESH:D006527 |
Hepatolenticular Degeneration |
|
Zinc |
5.34 | 17276780 |
| MESH:D007511 |
Ischemia |
|
Zinc |
5.28 | 16584753 |
| MESH:D007674 |
Kidney Diseases |
|
Zinc |
3.54 | 16960431 |
| MESH:D007676 |
Kidney Failure, Chronic |
|
Zinc |
4.90 | 16518626 |
| MESH:D007938 |
Leukemia |
|
arsenic trioxide |
3.01 | 15070760 |
| MESH:D015459 |
Leukemia-Lymphoma, Adult T-Cell |
|
arsenic trioxide |
4.28 | 12560223 17077332 |
| MESH:D007948 |
Leukemia, Monocytic, Acute |
|
arsenic trioxide |
5.05 | 16972261 |
| MESH:D015464 |
Leukemia, Myelogenous, Chronic, BCR-ABL Positive |
|
arsenic trioxide |
3.75 | 14633726 |
| MESH:D007951 |
Leukemia, Myeloid |
|
arsenic trioxide |
4.24 | 19077051 |
| MESH:D015470 |
Leukemia, Myeloid, Acute |
|
arsenic trioxide |
2.19 | 16467208 19850784 20471514 17050201 16968895 |
| MESH:D015473 |
Leukemia, Promyelocytic, Acute |
|
arsenic trioxide |
3.48 | 9834237 11161223 15336539 17869043 15748426 12018890 11468182 17649720 16331271 16966277 16112521 16823087 16330433 17217047 19642359 19225113 19035177 12679006 12712474 15213294 17107899 16891316 17712046 15622746 19075265 |
| MESH:D015458 |
Leukemia, T-Cell |
|
arsenic trioxide |
4.94 | 16882451 |
| MESH:D008113 |
Liver Neoplasms |
|
arsenic trioxide |
2.47 | 14682389 |
| MESH:D008114 |
Liver Neoplasms, Experimental |
|
arsenic trioxide |
2.98 | 20377131 |
| MESH:D008133 |
Long QT Syndrome |
|
arsenic trioxide |
3.69 | 15213294 |
| MESH:D008175 |
Lung Neoplasms |
|
arsenic trioxide |
1.87 | 11798837 19825857 |
| MESH:D008325 |
Mammary Neoplasms, Experimental |
|
Zinc |
3.56 | 12773700 |
| MESH:D009101 |
Multiple Myeloma |
|
arsenic trioxide |
3.41 | 19417148 11468182 19549372 15949261 14977855 |
| MESH:D009182 |
Mycosis Fungoides |
|
arsenic trioxide |
5.54 | 18349030 |
| MESH:D009190 |
Myelodysplastic Syndromes |
|
arsenic trioxide |
3.36 | 16882451 16105982 |
| MESH:D009361 |
Neoplasm Invasiveness |
|
arsenic trioxide |
4.54 | 16624393 |
| MESH:D009436 |
Neural Tube Defects |
|
arsenic trioxide |
3.38 | 10525206 |
| MESH:D010051 |
Ovarian Neoplasms |
|
arsenic trioxide |
2.51 | 19769630 12452020 16624393 |
| MESH:D010190 |
Pancreatic Neoplasms |
|
arsenic trioxide |
2.64 | 15580305 |
| MESH:D010235 |
Paraganglioma |
|
arsenic trioxide |
4.69 | 19927285 |
| MESH:D011225 |
Pre-Eclampsia |
|
Zinc |
4.52 | 17114810 |
| MESH:D011471 |
Prostatic Neoplasms |
|
arsenic trioxide |
3.40 | 19131511 |
| MESH:D011471 |
Prostatic Neoplasms |
|
Zinc |
3.40 | 16700911 16606632 16517595 12429649 |
| MESH:D012162 |
Retinal Degeneration |
|
Zinc |
4.45 | 16584753 |
| MESH:D012512 |
Sarcoma, Ewing's |
|
arsenic trioxide |
4.54 | 16646077 |
| MESH:D012878 |
Skin Neoplasms |
|
tert-Butylhydroperoxide |
2.86 | 8532709 |
| MESH:D013274 |
Stomach Neoplasms |
|
arsenic trioxide |
1.86 | 17007042 |
| MESH:D013964 |
Thyroid Neoplasms |
|
arsenic trioxide |
3.43 | 19014326 |
| MESH:D014062 |
Tongue Neoplasms |
|
Zinc |
4.85 | 16543248 |
| MESH:D016171 |
Torsades de Pointes |
|
arsenic trioxide |
4.70 | 15213294 |
| MESH:D001749 |
Urinary Bladder Neoplasms |
|
arsenic trioxide |
2.61 | 12973940 11780464 20435036 12845720 |
Related Pathway Information