Annotation Detail for DENND4C
Basic Information
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| Gene Symbol: | DENND4C ( C9orf55,C9orf55B,DKFZp686I09113,FLJ20686,bA513M16.3 ) |
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| Gene Full Name: | DENN/MADD domain containing 4C |
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| Band: | 9p22.1 |
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| Quick Links | Entrez ID:55667; OMIM: NA; Uniprot ID:DEN4C_HUMAN; ENSEMBL ID: ENSG00000137145; HGNC ID: 26079 |
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| Relate to Another Database: |
SFARIGene;
denovo-db |
| Chemical ID |
Chemical Name |
Interaction |
Interaction Action |
Publication |
|---|
| D001564 |
Benzo(a)pyrene |
Benzo(a)pyrene results in decreased expression of DENND4C mRNA | decreases expression | 20064835
|
| D015123 |
7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide |
7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in decreased expression of DENND4C mRNA | decreases expression | 19150397
|
| D002117 |
Calcitriol |
Calcitriol results in increased expression of DENND4C mRNA | increases expression | 16002434
|
| Disease ID |
Disease Name |
Direct Evidence |
Inference Chemical Name |
Inference Score |
Publication |
|---|
| MESH:D000230 |
Adenocarcinoma |
|
Benzo(a)pyrene |
2.06 | 20127859 20464547 |
| MESH:D000236 |
Adenoma |
|
Benzo(a)pyrene |
2.88 | 6695378 |
| MESH:D017544 |
Aortic Aneurysm, Abdominal |
|
Benzo(a)pyrene |
4.73 | 19183758 |
| MESH:D001943 |
Breast Neoplasms |
|
Benzo(a)pyrene |
2.19 | 17474063 20146248 |
| MESH:D001943 |
Breast Neoplasms |
|
Calcitriol |
2.19 | 11237771 |
| MESH:D002294 |
Carcinoma, Squamous Cell |
|
Benzo(a)pyrene |
5.02 | 20419170 |
| MESH:D002294 |
Carcinoma, Squamous Cell |
|
Calcitriol |
5.02 | 11237771 |
| MESH:D002471 |
Cell Transformation, Neoplastic |
|
7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide |
3.01 | 20889678 |
| MESH:D004681 |
Encephalomyelitis, Autoimmune, Experimental |
|
Calcitriol |
4.52 | 15138306 |
| MESH:D004938 |
Esophageal Neoplasms |
|
7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide |
4.64 | 20426865 |
| MESH:D004938 |
Esophageal Neoplasms |
|
Benzo(a)pyrene |
4.64 | 16530937 |
| MESH:D006330 |
Heart Defects, Congenital |
|
Benzo(a)pyrene |
2.85 | 20471113 |
| MESH:D008113 |
Liver Neoplasms |
|
Benzo(a)pyrene |
2.17 | 21137059 20195826 |
| MESH:D008175 |
Lung Neoplasms |
|
Benzo(a)pyrene |
1.57 | 20064080 18569708 6695378 18816296 20464547 20869020 17053015 20135361 18520028 |
| MESH:D009062 |
Mouth Neoplasms |
|
Benzo(a)pyrene |
3.53 | 16381670 |
| MESH:D009369 |
Neoplasms |
|
Benzo(a)pyrene |
2.35 | 11141357 |
| MESH:D011470 |
Prostatic Hyperplasia |
|
Calcitriol |
5.52 | 15572423 |
| MESH:D011471 |
Prostatic Neoplasms |
|
Benzo(a)pyrene |
3.19 | 17292933 |
| MESH:D011471 |
Prostatic Neoplasms |
|
Calcitriol |
3.19 | 15754350 18247401 16289102 12479363 16644109 |
| MESH:D012878 |
Skin Neoplasms |
|
Benzo(a)pyrene |
2.54 | 19755658 10029692 |
| MESH:D013274 |
Stomach Neoplasms |
|
Benzo(a)pyrene |
1.56 | 2093021 20155912 |
| MESH:D001749 |
Urinary Bladder Neoplasms |
|
Benzo(a)pyrene |
2.31 | 17053015 |
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