AutismKB 2.0

Annotation Detail for PEX26


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Basic Information Top
Gene Symbol:PEX26 ( FLJ20695,PEX26M1T,Pex26pM1T )
Gene Full Name: peroxisomal biogenesis factor 26
Band: 22q11.21
Quick LinksEntrez ID:55670; OMIM: 608666; Uniprot ID:PEX26_HUMAN; ENSEMBL ID: ENSG00000215193; HGNC ID: 22965
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
Related Diseases/Disorders Top
Desease IDDesease Name
H00205Zellweger syndrome spectrum
Peroxisomal diseases
Genetic disorders
No data
No data
No data
Desease Name
Refsum disease, infantile form
Adrenoleukodystrophy, neonatal
Zellweger syndrome
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
D000082 Acetaminophen Acetaminophen affects the expression of PEX26 mRNAaffects expression 17562736
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
OMIM:202370 ADRENOLEUKODYSTROPHY, AUTOSOMAL NEONATAL FORM marker/mechanism
MESH:D000799 Angioedema Acetaminophen 5.2610982225
MESH:D001321 Autistic Disorder Acetaminophen 1.3918445737
MESH:D006528 Carcinoma, Hepatocellular Acetaminophen 1.413084413
MESH:D002386 Cataract Acetaminophen 2.8610977129
MESH:D056486 Drug-Induced Liver Injury Acetaminophen 1.6917522070 19923254 11461765 12540782 18071297 12153990 16227642 19164858 16109766 19420014 19416960 11529661 16081117 12392966 11834606 12594235 16177239 2444490 14986274 11743745 15968718 17906064 17562736 14550746 19739265 15619225 16781746 11287661 12958197 11739529 14725611 12705907 19370779 16393943 19085960 10663392 16485898 18713872 10774834 10915739 11421492
MESH:D056487 Drug-Induced Liver Injury, Chronic Acetaminophen 5.5119426721
MESH:D005756 Gastritis Acetaminophen 5.0916983495
MESH:D006930 Hyperalgesia Acetaminophen 3.1516870215
MESH:D007674 Kidney Diseases Acetaminophen 2.4712587719 15629191
MESH:D008107 Liver Diseases Acetaminophen 1.7212969438 19784758 19460945 11587558 19014921 16611625 12587719 16610002
MESH:D017114 Liver Failure, Acute Acetaminophen 3.8117185352 16871587
MESH:D008546 Melanoma, Experimental Acetaminophen 4.4719513568
MESH:D019636 Neurodegenerative Diseases Acetaminophen 3.3618514411
MESH:D010146 Pain Acetaminophen 2.8716870215
MESH:D018901 Peroxisomal Disorders marker/mechanism
MESH:D052919 Refsum Disease, Infantile marker/mechanism
MESH:D014581 Urticaria Acetaminophen 3.6710982225
MESH:D015211 Zellweger Syndrome marker/mechanism
Pathway ID Pathway Name
KEGG:04146 Peroxisome
Pharmacogenomics Knowledge Base Top
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  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018