AutismKB 2.0

Annotation Detail for TRMU


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:TRMU ( MGC99627,MTO2,MTU1,TRMT,TRMT1,TRNT1 )
Gene Full Name: tRNA 5-methylaminomethyl-2-thiouridylate methyltransferase
Band: 22q13.31
Quick LinksEntrez ID:55687; OMIM: 610230; Uniprot ID:MTU1_HUMAN; ENSEMBL ID: ENSG00000100416; HGNC ID: 25481
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
Related Diseases/Disorders Top
No data
No data
No data
No data
Desease Name
Liver failure, acute infantile
Deafness, mitochondrial, modifier of
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C016403 2,4-dinitrotoluene 2,4-dinitrotoluene affects the expression of TRMU mRNAaffects expression 21346803
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D006528 Carcinoma, Hepatocellular 2,4-dinitrotoluene 1.7916705839
MESH:D003490 Cyanosis 2,4-dinitrotoluene 4.9218551238
OMIM:580000 DEAFNESS, AMINOGLYCOSIDE-INDUCED marker/mechanism
MESH:D056486 Drug-Induced Liver Injury 2,4-dinitrotoluene 2.0721346803 18551238
MESH:D007680 Kidney Neoplasms 2,4-dinitrotoluene 3.4616705839
OMIM:613070 LIVER FAILURE, ACUTE INFANTILE marker/mechanism
MESH:D009336 Necrosis 2,4-dinitrotoluene 4.9518551238
MESH:D009784 Occupational Diseases 2,4-dinitrotoluene 4.0016049721 12819281
MESH:D012640 Seizures 2,4-dinitrotoluene 2.8818551238
MESH:D001749 Urinary Bladder Neoplasms 2,4-dinitrotoluene 2.4416049721
MESH:D014571 Urologic Neoplasms 2,4-dinitrotoluene 5.4010091137
Pathway ID Pathway Name
KEGG:04122 Sulfur relay system
Pharmacogenomics Knowledge Base Top
  • PharmGKB Accession:PA142670701
  • No data
    Releated disease ID Related disease Name
    PA145069464Deafness,nonsyndromic
    No data
    Drug Bank Top

    Simple Query:


      (e.g. CHD8)

    Syndromic Genes

    Non-syndromic Genes

    AutismKB Statistics

    • Studies: 1,036
    • Genes: 1,379
    • CNVs/SVs: 5,420
    • SNVs/Indels: 11,669
    • de novo Mutations: 5,669
    • Mosaics: 789
    • Linkage Regions: 172
    • Paper Collected: 6/30/2018
    • Last Update: 8/26/2018