AutismKB 2.0

Annotation Detail for PACS1


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:PACS1 ( FLJ10209,KIAA1175 )
Gene Full Name: phosphofurin acidic cluster sorting protein 1
Band: 11q13.1-q13.2
Quick LinksEntrez ID:55690; OMIM: 607492; Uniprot ID:PACS1_HUMAN; ENSEMBL ID: ENSG00000175115; HGNC ID: 30032
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
No data
No data
Pathway IDPathway Name
HIV Infection
No data
No data
Pathway IDPathway Name
500758Nef mediated downregulation of MHC class I complex cell surface expression
Related Diseases/Disorders Top
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C016403 2,4-dinitrotoluene 2,4-dinitrotoluene affects the expression of PACS1 mRNAaffects expression 21346803
D000643 Ammonium Chloride Ammonium Chloride affects the expression of PACS1 mRNAaffects expression 16483693
D004997 Ethinyl Estradiol Ethinyl Estradiol results in decreased expression of PACS1 mRNAdecreases expression 12655037
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000138 Acidosis Ammonium Chloride 4.3018287403
MESH:D000152 Acne Vulgaris Ethinyl Estradiol 4.8117505938
MESH:D000230 Adenocarcinoma Ethinyl Estradiol 1.8914692618
MESH:D001161 Arteriosclerosis Ethinyl Estradiol 4.1211256880
MESH:D001169 Arthritis, Experimental Ethinyl Estradiol 2.9115885639
MESH:D006528 Carcinoma, Hepatocellular 2,4-dinitrotoluene 1.7916705839
MESH:D002779 Cholestasis Ethinyl Estradiol 3.2017681005 16919318 16105132 17333356 17110522 15861022 11677210
MESH:D003490 Cyanosis 2,4-dinitrotoluene 4.6718551238
MESH:D056486 Drug-Induced Liver Injury 2,4-dinitrotoluene 2.0621346803 18551238
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Ethinyl Estradiol 3.7712538720
MESH:D005234 Fatty Liver Ethinyl Estradiol 3.2915345470
MESH:D007021 Hypospadias Ethinyl Estradiol 4.4616945680 16569931
MESH:D007247 Infertility, Female Ethinyl Estradiol 3.9912013081
MESH:D007248 Infertility, Male Ethinyl Estradiol 2.7617937319
MESH:D007680 Kidney Neoplasms 2,4-dinitrotoluene 3.3616705839
MESH:D009336 Necrosis 2,4-dinitrotoluene 4.6018551238
MESH:D009784 Occupational Diseases 2,4-dinitrotoluene 3.8816049721 12819281
MESH:D016584 Panic Disorder Ethinyl Estradiol 4.2211578682
MESH:D011537 Pruritus Ethinyl Estradiol 4.0515861022 16919318
MESH:D012640 Seizures 2,4-dinitrotoluene 2.8118551238
MESH:D013088 Spermatocele Ethinyl Estradiol 4.8116709447
MESH:D019851 Thrombophilia Ethinyl Estradiol 4.1511994571
MESH:D013927 Thrombosis Ethinyl Estradiol 3.5715669648
MESH:D001749 Urinary Bladder Neoplasms 2,4-dinitrotoluene 2.4216049721
MESH:D014571 Urologic Neoplasms 2,4-dinitrotoluene 5.0610091137
MESH:D014594 Uterine Neoplasms Ethinyl Estradiol 3.8814692618
MESH:D020246 Venous Thrombosis Ethinyl Estradiol 4.0215869587 14671159
Pathway ID Pathway Name
REACT:6185 HIV Infection
Pharmacogenomics Knowledge Base Top
Drug Bank Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


Copyright © 2017, Center for Bioinformatics , Peking University | All Rights Reserved