AutismKB 2.0

Annotation Detail for LUC7L


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Basic Information Top
Gene Symbol:LUC7L ( FLJ10231,LUC7-LIKE,LUC7B1,Luc7,SR+89,hLuc7B1 )
Gene Full Name: LUC7-like (S. cerevisiae)
Band: 16p13.3
Quick LinksEntrez ID:55692; OMIM: 607782; Uniprot ID:LUC7L_HUMAN; ENSEMBL ID: ENSG00000007392; HGNC ID: 6723
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
Related Diseases/Disorders Top
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C016403 2,4-dinitrotoluene 2,4-dinitrotoluene affects the expression of LUC7L mRNAaffects expression 21346803
C009505 4,4'-diaminodiphenylmethane 4,4'-diaminodiphenylmethane results in increased expression of LUC7L mRNAincreases expression 18648102
D000082 Acetaminophen Acetaminophen affects the expression of LUC7L mRNAaffects expression 17562736
C006253 pirinixic acid pirinixic acid results in increased expression of LUC7L mRNAincreases expression 18301758
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D055371 Acute Lung Injury pirinixic acid 3.5818653653
MESH:D000236 Adenoma 4,4'-diaminodiphenylmethane 2.963712494
MESH:D018248 Adenoma, Liver Cell pirinixic acid 4.1116434500
MESH:D000799 Angioedema Acetaminophen 4.5710982225
MESH:D001321 Autistic Disorder Acetaminophen 1.4018445737
MESH:D001660 Biliary Tract Diseases 4,4'-diaminodiphenylmethane 5.741440618 11289319
MESH:D001778 Blood Coagulation Disorders pirinixic acid 3.5719483382
MESH:D006528 Carcinoma, Hepatocellular 2,4-dinitrotoluene 4.7816705839
MESH:D006528 Carcinoma, Hepatocellular 4,4'-diaminodiphenylmethane 4.787296757 3581430
MESH:D006528 Carcinoma, Hepatocellular Acetaminophen 4.783084413
MESH:D002292 Carcinoma, Renal Cell 4,4'-diaminodiphenylmethane 2.837296757
MESH:D002386 Cataract Acetaminophen 2.7910977129
MESH:D002471 Cell Transformation, Neoplastic 4,4'-diaminodiphenylmethane 3.027505956
MESH:D002779 Cholestasis 4,4'-diaminodiphenylmethane 8.8319486331 9022650
MESH:D002779 Cholestasis pirinixic acid 8.8319176532
MESH:D003490 Cyanosis 2,4-dinitrotoluene 4.5818551238
MESH:D017449 Dermatitis, Allergic Contact 4,4'-diaminodiphenylmethane 3.3511298694 12868966 18759878 8156756 2524372 14531868 11906362 8970840
MESH:D003876 Dermatitis, Atopic pirinixic acid 2.5718249437
MESH:D003877 Dermatitis, Contact 4,4'-diaminodiphenylmethane 3.953621924 2952479
MESH:D056486 Drug-Induced Liver Injury 2,4-dinitrotoluene 6.7221346803 18551238
MESH:D056486 Drug-Induced Liver Injury 4,4'-diaminodiphenylmethane 6.7218692083 6482804 18289764 7440962 11289319 1440618 16192314 6679447 9022650 9328219 8291058 18648102 9653073
MESH:D056486 Drug-Induced Liver Injury Acetaminophen 6.7216485898 11461765 11739529 17522070 11743745 11421492 17906064 18071297 18713872 16109766 19420014 16227642 16393943 19739265 19164858 12705907 12153990 12958197 10663392 16177239 12594235 16081117 17562736 15968718 14550746 10915739 11529661 14725611 12540782 12392966 19370779 19416960 2444490 11287661 19923254 10774834 15619225 11834606 16781746 14986274 19085960
MESH:D056487 Drug-Induced Liver Injury, Chronic Acetaminophen 4.8219426721
MESH:D004487 Edema pirinixic acid 2.9012083418
MESH:D004938 Esophageal Neoplasms 4,4'-diaminodiphenylmethane 2.183581430
MESH:D005234 Fatty Liver pirinixic acid 3.1919236843 20131406
MESH:D005350 Fibroma 4,4'-diaminodiphenylmethane 5.746705139
MESH:D005756 Gastritis Acetaminophen 4.4016983495
MESH:D006042 Goiter 4,4'-diaminodiphenylmethane 4.507505956
MESH:D006333 Heart Failure pirinixic acid 2.7620558911
MESH:D006505 Hepatitis 4,4'-diaminodiphenylmethane 4.026705139
MESH:D006529 Hepatomegaly pirinixic acid 3.5519772884 18467677 19176532 16221962
MESH:D006930 Hyperalgesia Acetaminophen 3.0216870215
MESH:D006943 Hyperglycemia pirinixic acid 3.5820558911
MESH:D006965 Hyperplasia 4,4'-diaminodiphenylmethane 4.5015034207
MESH:D007333 Insulin Resistance pirinixic acid 2.8716306350
MESH:D007565 Jaundice 4,4'-diaminodiphenylmethane 5.748074119 9022650
MESH:D007674 Kidney Diseases Acetaminophen 2.4015629191 12587719
MESH:D007680 Kidney Neoplasms 2,4-dinitrotoluene 8.5216705839
MESH:D007680 Kidney Neoplasms 4,4'-diaminodiphenylmethane 8.526582329
MESH:D008105 Liver Cirrhosis, Biliary 4,4'-diaminodiphenylmethane 3.4215034207 9327722
MESH:D008106 Liver Cirrhosis, Experimental pirinixic acid 1.3515474484
MESH:D008107 Liver Diseases Acetaminophen 1.7019784758 19014921 16610002 19460945 16611625 12969438 11587558 12587719
MESH:D017114 Liver Failure, Acute Acetaminophen 3.6317185352 16871587
MESH:D008113 Liver Neoplasms pirinixic acid 1.9315890375 20007298 16377806
MESH:D008114 Liver Neoplasms, Experimental 4,4'-diaminodiphenylmethane 2.751399818 598648 3712494 6587162
MESH:D008546 Melanoma, Experimental Acetaminophen 4.1319513568
MESH:D009135 Muscular Diseases pirinixic acid 4.0716239165
MESH:D009203 Myocardial Infarction pirinixic acid 2.2719151258
MESH:D015428 Myocardial Reperfusion Injury pirinixic acid 3.2516411023
MESH:D009336 Necrosis 2,4-dinitrotoluene 4.4918551238
MESH:D009362 Neoplasm Metastasis 4,4'-diaminodiphenylmethane 2.593581430
MESH:D009369 Neoplasms pirinixic acid 2.1117405874
MESH:D009436 Neural Tube Defects 4,4'-diaminodiphenylmethane 3.156679447
MESH:D019636 Neurodegenerative Diseases Acetaminophen 3.2118514411
MESH:D009765 Obesity pirinixic acid 1.8820558911
MESH:D009784 Occupational Diseases 2,4-dinitrotoluene 10.2216049721 12819281
MESH:D009784 Occupational Diseases 4,4'-diaminodiphenylmethane 10.224026338 6482804
MESH:D009902 Optic Neuritis 4,4'-diaminodiphenylmethane 5.743988306
MESH:D010146 Pain Acetaminophen 2.7316870215
MESH:D010212 Papilloma 4,4'-diaminodiphenylmethane 4.047296757
MESH:D010787 Photosensitivity Disorders 4,4'-diaminodiphenylmethane 5.196228378
MESH:D015427 Reperfusion Injury pirinixic acid 2.5519058328
MESH:D012162 Retinal Degeneration 4,4'-diaminodiphenylmethane 3.673692021
MESH:D012640 Seizures 2,4-dinitrotoluene 2.7918551238
MESH:D013964 Thyroid Neoplasms 4,4'-diaminodiphenylmethane 3.196582329 3712494 7505956 1399818 6587162
MESH:D001749 Urinary Bladder Neoplasms 2,4-dinitrotoluene 5.4316049721
MESH:D001749 Urinary Bladder Neoplasms 4,4'-diaminodiphenylmethane 5.438074119
MESH:D014571 Urologic Neoplasms 2,4-dinitrotoluene 4.9510091137
MESH:D014581 Urticaria Acetaminophen 3.4410982225
No data
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AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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