Annotation Detail for POLR3B
Basic Information
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| Gene Symbol: | POLR3B ( C128,DKFZp686B10117,FLJ10388,RPC2 ) |
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| Gene Full Name: | polymerase (RNA) III (DNA directed) polypeptide B |
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| Band: | 12q23.3 |
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| Quick Links | Entrez ID:55703; OMIM: NA; Uniprot ID:RPC2_HUMAN; ENSEMBL ID: ENSG00000013503; HGNC ID: 30348 |
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| Relate to Another Database: |
SFARIGene;
denovo-db |
| Pathway ID | Pathway Name |
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| Transcription |
| Desease Name |
|---|
| NEUROLOGICAL |
| Cognitive test performance |
| Desease Name |
|---|
| Cognitive test performance |
| Chemical ID |
Chemical Name |
Interaction |
Interaction Action |
Publication |
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| D001564 |
Benzo(a)pyrene |
Benzo(a)pyrene results in decreased expression of POLR3B mRNA | decreases expression | 20064835
|
| D015123 |
7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide |
7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide affects the expression of POLR3B mRNA | affects expression | 20382639
|
| D015123 |
7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide |
7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in decreased expression of POLR3B mRNA | decreases expression | 19150397
|
| Disease ID |
Disease Name |
Direct Evidence |
Inference Chemical Name |
Inference Score |
Publication |
|---|
| MESH:D000230 |
Adenocarcinoma |
|
Benzo(a)pyrene |
2.07 | 20127859 20464547 |
| MESH:D000236 |
Adenoma |
|
Benzo(a)pyrene |
2.90 | 6695378 |
| MESH:D017544 |
Aortic Aneurysm, Abdominal |
|
Benzo(a)pyrene |
4.84 | 19183758 |
| MESH:D001943 |
Breast Neoplasms |
|
Benzo(a)pyrene |
1.98 | 20146248 17474063 |
| MESH:D002294 |
Carcinoma, Squamous Cell |
|
Benzo(a)pyrene |
2.15 | 20419170 |
| MESH:D002471 |
Cell Transformation, Neoplastic |
|
7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide |
3.04 | 20889678 |
| MESH:D004938 |
Esophageal Neoplasms |
|
7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide |
4.66 | 20426865 |
| MESH:D004938 |
Esophageal Neoplasms |
|
Benzo(a)pyrene |
4.66 | 16530937 |
| MESH:D006330 |
Heart Defects, Congenital |
|
Benzo(a)pyrene |
2.87 | 20471113 |
| MESH:D008113 |
Liver Neoplasms |
|
Benzo(a)pyrene |
2.18 | 20195826 21137059 |
| MESH:D008175 |
Lung Neoplasms |
|
Benzo(a)pyrene |
1.57 | 20135361 20464547 18520028 18569708 20869020 18816296 17053015 20064080 6695378 |
| MESH:D009062 |
Mouth Neoplasms |
|
Benzo(a)pyrene |
3.57 | 16381670 |
| MESH:D009369 |
Neoplasms |
|
Benzo(a)pyrene |
2.36 | 11141357 |
| MESH:D011471 |
Prostatic Neoplasms |
|
Benzo(a)pyrene |
2.90 | 17292933 |
| MESH:D012878 |
Skin Neoplasms |
|
Benzo(a)pyrene |
2.55 | 19755658 10029692 |
| MESH:D013274 |
Stomach Neoplasms |
|
Benzo(a)pyrene |
1.56 | 2093021 20155912 |
| MESH:D001749 |
Urinary Bladder Neoplasms |
|
Benzo(a)pyrene |
2.32 | 17053015 |
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