AutismKB 2.0

Annotation Detail for ASF1B


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:ASF1B ( CIA-II,FLJ10604 )
Gene Full Name: ASF1 anti-silencing function 1 homolog B (S. cerevisiae)
Band: 19p13.12
Quick LinksEntrez ID:55723; OMIM: 609190; Uniprot ID:ASF1B_HUMAN; ENSEMBL ID: ENSG00000105011; HGNC ID: 20996
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
Related Diseases/Disorders Top
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C010914 2,4-diaminotoluene 2,4-diaminotoluene results in increased expression of ASF1B mRNAincreases expression 20713471
D016604 Aflatoxin B1 Aflatoxin B1 affects the expression of ASF1B proteinaffects expression 20106945
C015001 arsenite arsenite results in decreased expression of ASF1B mRNAdecreases expression 18929588
D001564 Benzo(a)pyrene Benzo(a)pyrene results in increased expression of ASF1B mRNAincreases expression 20504355
D015123 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in decreased expression of ASF1B mRNAdecreases expression 20382639
C006780 bisphenol A bisphenol A results in increased expression of ASF1B mRNAincreases expression 20739668
D020122 tert-Butylhydroperoxide tert-Butylhydroperoxide results in decreased expression of ASF1B mRNAdecreases expression 15336504
D002251 Carbon Tetrachloride Carbon Tetrachloride results in increased expression of ASF1B mRNAincreases expression 17484886
D016572 Cyclosporine Cyclosporine results in decreased expression of ASF1B mRNAdecreases expression 20106945
D004052 Diethylnitrosamine Diethylnitrosamine results in increased expression of ASF1B mRNAincreases expression 17854601
D004052 Diethylnitrosamine RB1 protein inhibits the reaction [Diethylnitrosamine results in increased expression of ASF1B mRNA]decreases reaction|increases expression 17854601
D004997 Ethinyl Estradiol Ethinyl Estradiol affects the expression of ASF1B mRNAaffects expression 17555576
D004997 Ethinyl Estradiol Ethinyl Estradiol results in increased expression of ASF1B mRNAincreases expression 17942748
D004997 Ethinyl Estradiol [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of ASF1B mRNAaffects cotreatment|increases expression 17942748
D008748 Methylcholanthrene Methylcholanthrene results in increased expression of ASF1B mRNAincreases expression 20713471
D010126 Ozone TTPA protein affects the reaction [Ozone results in increased expression of ASF1B mRNA]affects reaction|increases expression 19555225
D010634 Phenobarbital NR1I3 protein affects the reaction [Phenobarbital results in increased expression of ASF1B mRNA]affects reaction|increases expression 19482888
D010634 Phenobarbital Phenobarbital results in increased expression of ASF1B mRNAincreases expression 19482888
D010634 Phenobarbital Phenobarbital results in increased expression of ASF1B mRNAincreases expression 12832660
C006253 pirinixic acid pirinixic acid results in increased expression of ASF1B mRNAincreases expression 18301758
17950772
C006253 pirinixic acid PPARA protein promotes the reaction [pirinixic acid results in increased expression of ASF1B mRNA]increases expression|increases reaction 17950772
C006253 pirinixic acid pirinixic acid results in increased expression of ASF1B mRNAincreases expression 12832660
D013629 Tamoxifen Tamoxifen affects the expression of ASF1B mRNAaffects expression 17555576
D013749 Tetrachlorodibenzodioxin [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of ASF1B mRNAaffects cotreatment|increases expression 17942748
D014212 Tretinoin Tretinoin results in decreased expression of ASF1B mRNAdecreases expression 16249480
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000008 Abdominal Neoplasms Tamoxifen 4.5214745880
MESH:D000014 Abnormalities, Drug-Induced Phenobarbital 8.186195326
MESH:D000014 Abnormalities, Drug-Induced Tetrachlorodibenzodioxin 8.1811752688 15322242 14514962
MESH:D000152 Acne Vulgaris Ethinyl Estradiol 3.9117505938
MESH:D055371 Acute Lung Injury pirinixic acid 3.0818653653
MESH:D000230 Adenocarcinoma Benzo(a)pyrene 4.1420127859 20464547
MESH:D000230 Adenocarcinoma Ethinyl Estradiol 4.1414692618
MESH:D000236 Adenoma Benzo(a)pyrene 11.086695378
MESH:D000236 Adenoma Diethylnitrosamine 11.086695378 10737359
MESH:D000236 Adenoma Methylcholanthrene 11.0810545420 6695378
MESH:D018248 Adenoma, Liver Cell Diethylnitrosamine 24.5919061943 17162532 16434500 17620307 19052882 18056438
MESH:D018248 Adenoma, Liver Cell Phenobarbital 24.5917620307
MESH:D018248 Adenoma, Liver Cell pirinixic acid 24.5916434500
MESH:D018248 Adenoma, Liver Cell Tetrachlorodibenzodioxin 24.5916835633
MESH:D000505 Alopecia Tretinoin 3.5815955085
MESH:D000544 Alzheimer Disease Ozone 2.4315513908
MESH:D000740 Anemia Tetrachlorodibenzodioxin 2.9111748828
MESH:D017544 Aortic Aneurysm, Abdominal Benzo(a)pyrene 4.0319183758
MESH:D001161 Arteriosclerosis Ethinyl Estradiol 3.4211256880
MESH:D001169 Arthritis, Experimental Ethinyl Estradiol 7.1115885639
MESH:D001169 Arthritis, Experimental Tretinoin 7.1116412693
MESH:D001172 Arthritis, Rheumatoid Ozone 4.6315570426
MESH:D001172 Arthritis, Rheumatoid Tretinoin 4.6316292516
MESH:D001249 Asthma Ozone 4.9116373670 17854713
MESH:D001249 Asthma Tretinoin 4.9116456186
MESH:D050197 Atherosclerosis Methylcholanthrene 3.4311922910
MESH:D001471 Barrett Esophagus Tretinoin 4.3616935849
MESH:D001778 Blood Coagulation Disorders pirinixic acid 15.0419483382
MESH:D001778 Blood Coagulation Disorders Tetrachlorodibenzodioxin 15.0412125929
MESH:D001778 Blood Coagulation Disorders Tretinoin 15.0416206674 16197459
MESH:D001836 Body Weight Changes Tetrachlorodibenzodioxin 3.7615340226
MESH:D001848 Bone Diseases, Developmental Tetrachlorodibenzodioxin 2.7315746008
MESH:D001862 Bone Resorption bisphenol A 3.8211985600
MESH:D001943 Breast Neoplasms 2,4-diaminotoluene 4.7111921183
MESH:D001943 Breast Neoplasms Benzo(a)pyrene 4.7117474063 20146248
MESH:D001943 Breast Neoplasms bisphenol A 4.7117123778
MESH:D001943 Breast Neoplasms Diethylnitrosamine 4.7117474063
MESH:D001943 Breast Neoplasms Methylcholanthrene 4.7117474063
MESH:D001943 Breast Neoplasms Tamoxifen 4.7119200415 18855134 21138602 19103187 19410462 20005174 16273361 20135344 16873071 20544844 17440819 11161223 19059307 18425577 17242785 19289846 16818667 16202921 19244106 19142967 20859285 18629630 19066611 19155303 20065188 19115204 18821012 18351453 21152245 18984771 18997820 17049068 15668708 18815881 17893378 19288272 20390343 19084267 19189212 19189210 19487384 17261762 19221464 15565566 19011961
MESH:D001943 Breast Neoplasms Tetrachlorodibenzodioxin 4.7120435547
MESH:D001943 Breast Neoplasms Tretinoin 4.7116873071 16443354 16166294
MESH:D016535 Bronchial Hyperreactivity Ozone 3.6417626835 15516495 19059883 18315731 16777450 18417511 14754758
MESH:D001997 Bronchopulmonary Dysplasia Tretinoin 4.5516813970
MESH:D002100 Cachexia Ozone 4.7016183385
MESH:D002252 Carbon Tetrachloride Poisoning Carbon Tetrachloride 3.7416097048 16192424 16124888 18705752 16011737 3786805 15721981 16050911 16227642 10355542 15673190 15700767
MESH:D002277 Carcinoma Methylcholanthrene 8.2110545420
MESH:D002277 Carcinoma Tetrachlorodibenzodioxin 8.2116835633
MESH:D018270 Carcinoma, Ductal, Breast Tamoxifen 4.4719066611
MESH:D018236 Carcinoma, Embryonal Tretinoin 5.1316168501
MESH:D006528 Carcinoma, Hepatocellular Aflatoxin B1 11.3121507988 12619106 12907637
MESH:D006528 Carcinoma, Hepatocellular Carbon Tetrachloride 11.3118788625
MESH:D006528 Carcinoma, Hepatocellular Diethylnitrosamine 11.3117138121 16779866 16569478 18785209 18506893 18494052 16878318 18971187 19701751 21159647 19919837 19107877 18788625 3084413 10672840 3581430 19208518 18393292 16288022 20935162 17173139 20007298 16935385 20524982 17055752 19383236 19539802 19335982 17978847 17428255 19171122 19822196 20214788 11831363 18665156 19052882 10737359 16807293 19418558 18210153 18978308 17162532 16502159 19394651 20512989 18691550 16698587 20101231 16540662 20432363 16328049 19519916 20727157 18056438 20514400 16681979 16830150 20084675 17761372
MESH:D006528 Carcinoma, Hepatocellular Phenobarbital 11.311701930 6705139 17173139 20007298 20935162
MESH:D006528 Carcinoma, Hepatocellular Tamoxifen 11.3116924424
MESH:D006528 Carcinoma, Hepatocellular Tretinoin 11.311917145
MESH:D002278 Carcinoma in Situ bisphenol A 4.9517123778
MESH:D002294 Carcinoma, Squamous Cell Benzo(a)pyrene 4.5220419170
MESH:D002294 Carcinoma, Squamous Cell Tretinoin 4.5216096774 16051514
MESH:D002295 Carcinoma, Transitional Cell Tamoxifen 3.5717572228
MESH:D006332 Cardiomegaly Tetrachlorodibenzodioxin 2.3416120746 18850075 18670907
MESH:D002386 Cataract Tretinoin 3.0717460283
MESH:D002471 Cell Transformation, Neoplastic 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 15.7920889678
MESH:D002471 Cell Transformation, Neoplastic Cyclosporine 15.7912371664
MESH:D002471 Cell Transformation, Neoplastic Diethylnitrosamine 15.7917174075 21159647 2727394 7505956
MESH:D002471 Cell Transformation, Neoplastic Methylcholanthrene 15.7916192471
MESH:D002493 Central Nervous System Diseases Phenobarbital 4.214080065
MESH:D018290 Cervical Intraepithelial Neoplasia Tretinoin 4.5516129372
MESH:D018281 Cholangiocarcinoma Diethylnitrosamine 9.2019052882
MESH:D018281 Cholangiocarcinoma Tetrachlorodibenzodioxin 9.2016835633
MESH:D002779 Cholestasis Cyclosporine 13.1519486331
MESH:D002779 Cholestasis Ethinyl Estradiol 13.1517333356 15861022 17110522 17681005 11677210 16105132 16919318
MESH:D002779 Cholestasis pirinixic acid 13.1519176532
MESH:D002822 Choriocarcinoma Tretinoin 5.1316461808
MESH:D002972 Cleft Palate Tetrachlorodibenzodioxin 5.7015340226 8697196 12621046 16354765 15668235
MESH:D002972 Cleft Palate Tretinoin 5.709407595
MESH:D003092 Colitis Tretinoin 3.6617035595
MESH:D003110 Colonic Neoplasms arsenite 2.5815037631
MESH:D000013 Congenital Abnormalities Tetrachlorodibenzodioxin 3.0214669216 17141729
MESH:D019465 Craniofacial Abnormalities Tetrachlorodibenzodioxin 2.4315322242 10048152 20055451
MESH:D019465 Craniofacial Abnormalities Tretinoin 2.439142499 17551590 9224671 10589399 14991402 16925845 9211117 8800419 9664655 9125849
MESH:D003711 Demyelinating Diseases Tamoxifen 4.3219031437
MESH:D003876 Dermatitis, Atopic pirinixic acid 2.4018249437
MESH:D003924 Diabetes Mellitus, Type 2 Diethylnitrosamine 4.1820387270
MESH:D003924 Diabetes Mellitus, Type 2 Tetrachlorodibenzodioxin 4.1817107852
MESH:D003928 Diabetic Nephropathies Tamoxifen 3.4419279558
MESH:D056486 Drug-Induced Liver Injury Carbon Tetrachloride 6.1110092053 19336974 6623471 9327722 6884620 3786805 15027814 3732212 11566570 7440962 7179309 17522070 15998439 7120509 10915739 16227642 15968718 4309450 2869522 21278145 19085960 16177239
MESH:D056486 Drug-Induced Liver Injury Diethylnitrosamine 6.1119107877
MESH:D056486 Drug-Induced Liver Injury Tetrachlorodibenzodioxin 6.1120420201
MESH:D004362 Drug Toxicity Tetrachlorodibenzodioxin 2.7311462148
MESH:D004421 Dystonia Phenobarbital 3.961851702
MESH:D004487 Edema pirinixic acid 6.4012083418
MESH:D004487 Edema Tetrachlorodibenzodioxin 6.4012711302 11000095
MESH:D004489 Edema, Cardiac Tetrachlorodibenzodioxin 11.8518230668 16714409 15322242
MESH:D004489 Edema, Cardiac Tretinoin 11.8518230668
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Ethinyl Estradiol 8.8112538720
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Tamoxifen 8.8119031437
MESH:D016889 Endometrial Neoplasms Tamoxifen 7.3420544844 17893378 19155303 16202921
MESH:D016889 Endometrial Neoplasms Tretinoin 7.3416569247
MESH:D004715 Endometriosis Tetrachlorodibenzodioxin 2.989294722 10568697
MESH:D004831 Epilepsies, Myoclonic Phenobarbital 4.073659116
MESH:D004828 Epilepsies, Partial Phenobarbital 3.8411558140 3922381
MESH:D004827 Epilepsy Phenobarbital 2.8720417680
MESH:D004832 Epilepsy, Absence Phenobarbital 3.506401628
MESH:D017029 Epilepsy, Complex Partial Phenobarbital 4.217750514
MESH:D004830 Epilepsy, Tonic-Clonic Phenobarbital 3.983659116
MESH:D004931 Esophageal Achalasia Diethylnitrosamine 5.0916302075
MESH:D004938 Esophageal Neoplasms 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 4.3120426865
MESH:D004938 Esophageal Neoplasms Benzo(a)pyrene 4.3116530937
MESH:D005124 Eye Abnormalities Tetrachlorodibenzodioxin 8.7211564622
MESH:D005124 Eye Abnormalities Tretinoin 8.7216938888 9664655
MESH:D005234 Fatty Liver arsenite 36.4318296743
MESH:D005234 Fatty Liver Carbon Tetrachloride 36.4317595544 16045604 19224547 15959796 61145 12795759 16239168 12631006
MESH:D005234 Fatty Liver Cyclosporine 36.4319224547
MESH:D005234 Fatty Liver Diethylnitrosamine 36.4320387270 21071580
MESH:D005234 Fatty Liver Ethinyl Estradiol 36.4315345470
MESH:D005234 Fatty Liver pirinixic acid 36.4319236843 20131406
MESH:D005234 Fatty Liver Tamoxifen 36.4314986274 19224547
MESH:D052776 Female Urogenital Diseases Tamoxifen 3.2116709447
MESH:D005313 Fetal Death Tetrachlorodibenzodioxin 3.4211858732
MESH:D018221 Fibromatosis, Abdominal Tamoxifen 4.4914745880
MESH:D018222 Fibromatosis, Aggressive Tamoxifen 4.1519069698
MESH:D005354 Fibrosarcoma Methylcholanthrene 4.9014633661 10962813
MESH:D005355 Fibrosis arsenite 27.3518296743
MESH:D005355 Fibrosis Carbon Tetrachloride 27.3518705752
MESH:D005355 Fibrosis Cyclosporine 27.3512168785 12639820
MESH:D005355 Fibrosis Tetrachlorodibenzodioxin 27.3520067830
MESH:D005355 Fibrosis Tretinoin 27.3517994277
MESH:D005885 Gingival Hyperplasia Cyclosporine 4.188708960
MESH:D005909 Glioblastoma Tretinoin 2.9817312396
MESH:D006058 Gonadal Disorders Tetrachlorodibenzodioxin 4.5710696789
MESH:D006258 Head and Neck Neoplasms Tretinoin 3.1516096774
MESH:D006317 Hearing Loss, Noise-Induced Tretinoin 5.1316084493
MESH:D006330 Heart Defects, Congenital Benzo(a)pyrene 10.9620471113
MESH:D006330 Heart Defects, Congenital Tetrachlorodibenzodioxin 10.9611294989 10048152
MESH:D006330 Heart Defects, Congenital Tretinoin 10.969664655 14991402
MESH:D006333 Heart Failure pirinixic acid 2.5120558911
MESH:D006457 Hemoglobinuria, Paroxysmal Cyclosporine 4.3915720958
MESH:D006470 Hemorrhage Tetrachlorodibenzodioxin 3.2911000095
MESH:D006505 Hepatitis Carbon Tetrachloride 3.5519110552 19900420
MESH:D006529 Hepatomegaly Phenobarbital 14.1616109766
MESH:D006529 Hepatomegaly pirinixic acid 14.1619176532 19772884 18467677 16221962
MESH:D006529 Hepatomegaly Tetrachlorodibenzodioxin 14.1612621046 16120746 15340226
MESH:D006869 Hydronephrosis Tetrachlorodibenzodioxin 4.0216354765 15340226 8697196 18606429 16959395
MESH:D006930 Hyperalgesia Tretinoin 3.1816870215
MESH:D006932 Hyperbilirubinemia Carbon Tetrachloride 4.5016899240
MESH:D017681 Hypereosinophilic Syndrome Tretinoin 4.5316778211
MESH:D006943 Hyperglycemia pirinixic acid 3.1420558911
MESH:D006973 Hypertension Cyclosporine 4.8910903974
MESH:D006973 Hypertension Tetrachlorodibenzodioxin 4.8918850075 18670907
MESH:D006975 Hypertension, Portal Carbon Tetrachloride 4.0515338365
MESH:D007021 Hypospadias Ethinyl Estradiol 3.7716945680 16569931
MESH:D007247 Infertility, Female Ethinyl Estradiol 3.4212013081
MESH:D007248 Infertility, Male Ethinyl Estradiol 2.4617937319
MESH:D007249 Inflammation Diethylnitrosamine 8.1418785209
MESH:D007249 Inflammation Tamoxifen 8.1419457130
MESH:D007249 Inflammation Tetrachlorodibenzodioxin 8.1412200463 12878042
MESH:D007333 Insulin Resistance bisphenol A 7.2216393666
MESH:D007333 Insulin Resistance pirinixic acid 7.2216306350
MESH:D007410 Intestinal Diseases Tretinoin 3.7317994277
MESH:D007569 Jaw Abnormalities Tetrachlorodibenzodioxin 9.8016580747
MESH:D007569 Jaw Abnormalities Tretinoin 9.8017551590 15992940
MESH:D007638 Keratoconjunctivitis Sicca Cyclosporine 4.4115604871
MESH:D007674 Kidney Diseases Cyclosporine 2.318314463 10903974 18776723
MESH:D007680 Kidney Neoplasms Cyclosporine 7.1712371664
MESH:D007680 Kidney Neoplasms Tamoxifen 7.1718625569
MESH:D007938 Leukemia Tretinoin 2.7517143497
MESH:D007951 Leukemia, Myeloid Tretinoin 3.6616482212 16932348 19285840
MESH:D015470 Leukemia, Myeloid, Acute Tretinoin 2.0717596541 19850784 16294345
MESH:D015473 Leukemia, Promyelocytic, Acute Tretinoin 3.1217107899 12679006 9834237 16788101 19642359 17361223 17712046 19075265 19035177 19225113 16823087 19029980 17217047 17506722 17649720 17368321 16140955 17301526 16891316 16935935 17294898 16766008 17339181 16331271 15748426
MESH:D017880 Limb Deformities, Congenital Tretinoin 3.279224671
MESH:D008064 Lipidoses Tamoxifen 3.1217567588 15342952
MESH:D008103 Liver Cirrhosis arsenite 15.5918296743
MESH:D008103 Liver Cirrhosis Carbon Tetrachloride 15.5916239168 17157831 17334410 16943688 17174718 16221502 21278145 11408273 11903743
MESH:D008103 Liver Cirrhosis Diethylnitrosamine 15.5920032147 18407596 18665156 19638242 18522880
MESH:D008103 Liver Cirrhosis Phenobarbital 15.5921047994
MESH:D008106 Liver Cirrhosis, Experimental Carbon Tetrachloride 6.6718472332 18420326 17869086 18054572 16638106 18429990 17922224 17565644 18412020 14716833 15338365 17698563 17805973 18317297 17761835 18279442 15931870 15959796 18395914 15052691 15673190 18006644 18210741 17823541 17708605 11481614 16248980 17900296 15730626 15650968 12632514 16015684 12649538 12389079 18472094 18705752 18277467 18205269 16136751 18481824 14748882 15370692 17481882 16097048 12586293 16116963 15818738 17976157 12632512 15057751 12958196 14716496 12546737 14724832 16192424 18263696 18376398 18166357 17557913 20821823 15362042 10355542 17525996 17721639 16027843 13678700 18251166 14620537 17714472 15893842 15876570 15925388 18156304 16011737 18187930 12609069 18418968 12666154 15123356 16033810 17766677 14512876 15996030 18395095 12898905 17944888 18339082 12445418 12445421 17631135 12741479 17640975 12667390
MESH:D008106 Liver Cirrhosis, Experimental pirinixic acid 6.6715474484
MESH:D008106 Liver Cirrhosis, Experimental Tamoxifen 6.6718564211
MESH:D008106 Liver Cirrhosis, Experimental Tetrachlorodibenzodioxin 6.6712878042
MESH:D008106 Liver Cirrhosis, Experimental Tretinoin 6.6716248980 18397230
MESH:D008107 Liver Diseases Carbon Tetrachloride 6.4816964402 15720792 17285989 15830285 16246199
MESH:D008107 Liver Diseases Diethylnitrosamine 6.4817034775
MESH:D008107 Liver Diseases Phenobarbital 6.4819363144
MESH:D017093 Liver Failure Carbon Tetrachloride 4.1215123358
MESH:D017114 Liver Failure, Acute Carbon Tetrachloride 3.6516899240 14706259
MESH:D008113 Liver Neoplasms Aflatoxin B1 25.7218177683 15890375 9163691 2125692
MESH:D008113 Liver Neoplasms Benzo(a)pyrene 25.7220195826 21137059
MESH:D008113 Liver Neoplasms Carbon Tetrachloride 25.7219294768
MESH:D008113 Liver Neoplasms Diethylnitrosamine 25.7216942905 21071580 20492335 19551842 15885732 19642983 18754104 20434301 20501860 2862719 19427195 19850985 19090486 19996281 20405173 19255062 19812893 21167192 9163691 2422723 18978307 20583210 20118626 19294768 19833225 21278145 18644402 19426721 21047994 20101389 19073162 18648771 19256749 18977376 20452335 19638242 10737359 19499222 15175105 12771043 20137499 19254457 12112319 19690152
MESH:D008113 Liver Neoplasms Phenobarbital 25.7219482888 19812893 15975961 8742319 19073162 21047994
MESH:D008113 Liver Neoplasms pirinixic acid 25.7216377806 15890375 20007298
MESH:D008113 Liver Neoplasms Tamoxifen 25.7216684651
MESH:D008113 Liver Neoplasms Tetrachlorodibenzodioxin 25.7216984957
MESH:D008114 Liver Neoplasms, Experimental Aflatoxin B1 23.038603461
MESH:D008114 Liver Neoplasms, Experimental Carbon Tetrachloride 23.0315583823 12014681
MESH:D008114 Liver Neoplasms, Experimental Diethylnitrosamine 23.0319539802 3124819 16267830 18544905 19009564 18093689 16842330 18164116 18282651 18775883 19519916 18079962 18308698 21159647 2563599 19126423 9362446 19004024 17854601 17942915 17174075 18253720
MESH:D008114 Liver Neoplasms, Experimental Methylcholanthrene 23.03598648 1399818
MESH:D008114 Liver Neoplasms, Experimental Phenobarbital 23.0317172636 1399818 2563599 18308698 6150874
MESH:D008114 Liver Neoplasms, Experimental Tetrachlorodibenzodioxin 23.0312151625
MESH:D008171 Lung Diseases Ozone 3.3519066396 8266340
MESH:D055370 Lung Injury Ozone 3.8120417186
MESH:D008175 Lung Neoplasms Aflatoxin B1 12.9314755239
MESH:D008175 Lung Neoplasms arsenite 12.9316809336
MESH:D008175 Lung Neoplasms Benzo(a)pyrene 12.9320869020 20464547 17053015 18569708 20064080 18816296 20135361 6695378 18520028
MESH:D008175 Lung Neoplasms Diethylnitrosamine 12.9320970405 20512841 21163286 6695378
MESH:D008175 Lung Neoplasms Methylcholanthrene 12.937750092 17909032 1399818 11893704 9230183 6695378 20970405 21163286 16271038 20512841 10545420 15390079 16337739
MESH:D008175 Lung Neoplasms Ozone 12.938597069 7614698
MESH:D008175 Lung Neoplasms Tamoxifen 12.9318625569
MESH:D008175 Lung Neoplasms Tetrachlorodibenzodioxin 12.9311884234 19555203
MESH:D015674 Mammary Neoplasms, Animal Tamoxifen 3.7219428831
MESH:D008325 Mammary Neoplasms, Experimental 2,4-diaminotoluene 6.2511921183
MESH:D008325 Mammary Neoplasms, Experimental Tamoxifen 6.2511731420 19196722 14580682 16827153 19196723
MESH:D020149 Manganese Poisoning Tamoxifen 4.5219453300
MESH:D008527 Medulloblastoma Tretinoin 2.7717453147
MESH:D008545 Melanoma Tamoxifen 3.2612393984 19393235
MESH:D008545 Melanoma Tretinoin 3.2616752155
MESH:D018328 Melanoma, Amelanotic Tamoxifen 4.1515990972
MESH:D008591 Meningomyelocele Tretinoin 4.3916940565
MESH:D008664 Metal Metabolism, Inborn Errors Cyclosporine 4.7616801185
MESH:D008679 Metaplasia Ozone 5.0810496685
MESH:D009062 Mouth Neoplasms Benzo(a)pyrene 3.1516381670
MESH:D009135 Muscular Diseases pirinixic acid 3.4716239165
MESH:D009190 Myelodysplastic Syndromes Tretinoin 3.0517596541
MESH:D009203 Myocardial Infarction pirinixic acid 2.1219151258
MESH:D017202 Myocardial Ischemia Tetrachlorodibenzodioxin 2.9812213967
MESH:D015428 Myocardial Reperfusion Injury pirinixic acid 2.9116411023
MESH:D020191 Myoclonic Epilepsies, Progressive Phenobarbital 4.4417484760
MESH:D009362 Neoplasm Metastasis Diethylnitrosamine 5.679029167 3581430
MESH:D009362 Neoplasm Metastasis Tamoxifen 5.6719393235
MESH:D009364 Neoplasm Recurrence, Local Tamoxifen 2.5019410462
MESH:D009369 Neoplasms Benzo(a)pyrene 8.0611141357
MESH:D009369 Neoplasms pirinixic acid 8.0617405874
MESH:D009369 Neoplasms Tretinoin 8.0616946489 16594593
MESH:D009376 Neoplasms, Hormone-Dependent Tamoxifen 3.9719200415 19196722 19189210
MESH:D009389 Neovascularization, Pathologic arsenite 4.3815738583
MESH:D009402 Nephrosis, Lipoid Cyclosporine 4.4117954296
MESH:D009404 Nephrotic Syndrome Cyclosporine 3.2419348381 18481113
MESH:D009421 Nervous System Malformations bisphenol A 16.1411399458 16427766
MESH:D009421 Nervous System Malformations Tetrachlorodibenzodioxin 16.1414600291
MESH:D009421 Nervous System Malformations Tretinoin 16.149125849
MESH:D009436 Neural Tube Defects Tretinoin 3.029142499
MESH:D019636 Neurodegenerative Diseases Diethylnitrosamine 3.3020387270
MESH:D009461 Neurologic Manifestations Diethylnitrosamine 5.0920387270
MESH:D009765 Obesity pirinixic acid 1.8020558911
MESH:D010018 Osteomalacia Phenobarbital 4.3317016548
MESH:D010049 Ovarian Diseases bisphenol A 4.9511985600
MESH:D010051 Ovarian Neoplasms Tretinoin 2.3316936753
MESH:D010146 Pain Tretinoin 2.8716870215
MESH:D010190 Pancreatic Neoplasms Diethylnitrosamine 8.5216540662
MESH:D010190 Pancreatic Neoplasms Phenobarbital 8.5216965848
MESH:D010190 Pancreatic Neoplasms Tretinoin 8.5215976015
MESH:D016584 Panic Disorder Ethinyl Estradiol 3.6511578682
MESH:D010382 Peliosis Hepatis Tetrachlorodibenzodioxin 4.2212520081
MESH:D010538 Peritonitis Ozone 4.0916369182
MESH:D011014 Pneumonia Ozone 4.3618007984 18929643 18381685
MESH:D017119 Porphyria Cutanea Tarda Tetrachlorodibenzodioxin 3.5218163543
MESH:D011230 Precancerous Conditions Cyclosporine 15.0512371664
MESH:D011230 Precancerous Conditions Diethylnitrosamine 15.052563599
MESH:D011230 Precancerous Conditions Phenobarbital 15.052563599
MESH:D011297 Prenatal Exposure Delayed Effects bisphenol A 9.3910548101
MESH:D011297 Prenatal Exposure Delayed Effects Tetrachlorodibenzodioxin 9.3911118676 11399792 11896295 11222880
MESH:D019048 Prostatic Intraepithelial Neoplasia bisphenol A 4.1720887781
MESH:D011471 Prostatic Neoplasms Benzo(a)pyrene 2.5617292933
MESH:D011471 Prostatic Neoplasms bisphenol A 2.5616740699
MESH:D011471 Prostatic Neoplasms Tamoxifen 2.5615067354
MESH:D011507 Proteinuria Tretinoin 3.5616636307
MESH:D011537 Pruritus Ethinyl Estradiol 3.2815861022 16919318
MESH:D019310 Pseudolymphoma Phenobarbital 4.4712752131
MESH:D011565 Psoriasis Cyclosporine 2.2116882103
MESH:D011625 Pterygium Tretinoin 4.7616723453
MESH:D011629 Puberty, Precocious bisphenol A 4.7510548101
MESH:D015427 Reperfusion Injury pirinixic acid 2.3619058328
MESH:D015619 Respiratory System Abnormalities Tetrachlorodibenzodioxin 3.8018990726
MESH:D012208 Rhabdomyosarcoma Tretinoin 4.0616283617 16116481
MESH:D012640 Seizures Phenobarbital 2.664039156 3137016 16876388 11442880
MESH:D003294 Seizures, Febrile Phenobarbital 4.796407741
MESH:D012878 Skin Neoplasms Benzo(a)pyrene 13.3819755658 10029692
MESH:D012878 Skin Neoplasms tert-Butylhydroperoxide 13.388532709
MESH:D012878 Skin Neoplasms Tetrachlorodibenzodioxin 13.3816192470
MESH:D012878 Skin Neoplasms Tretinoin 13.3816467112
MESH:D013088 Spermatocele Ethinyl Estradiol 11.4716709447
MESH:D013088 Spermatocele Tamoxifen 11.4716709447
MESH:D013119 Spinal Cord Injuries Tamoxifen 4.0019457130
MESH:D013274 Stomach Neoplasms Benzo(a)pyrene 3.302093021 20155912
MESH:D013274 Stomach Neoplasms Diethylnitrosamine 3.3018456281
MESH:D013274 Stomach Neoplasms Tretinoin 3.3017261132
MESH:D019966 Substance-Related Disorders bisphenol A 3.9516045194 16684133
MESH:D019851 Thrombophilia Ethinyl Estradiol 3.5811994571
MESH:D013927 Thrombosis Ethinyl Estradiol 3.1115669648
MESH:D013959 Thyroid Diseases Tetrachlorodibenzodioxin 3.8712697716
MESH:D013964 Thyroid Neoplasms Diethylnitrosamine 11.777505956
MESH:D013964 Thyroid Neoplasms Phenobarbital 11.771399818
MESH:D013964 Thyroid Neoplasms Tretinoin 11.7716026305 17045167
MESH:D014062 Tongue Neoplasms Tretinoin 3.7516051514
MESH:D014376 Tuberculosis Tretinoin 3.2016040207
MESH:D001749 Urinary Bladder Neoplasms Benzo(a)pyrene 4.9417053015
MESH:D001749 Urinary Bladder Neoplasms Tamoxifen 4.948653321 16712894 17572228
MESH:D002583 Uterine Cervical Neoplasms Tretinoin 3.6416129372
MESH:D014591 Uterine Diseases bisphenol A 4.9814652134
MESH:D014594 Uterine Neoplasms Ethinyl Estradiol 3.2614692618
MESH:D014604 Uveal Neoplasms Tretinoin 4.5816752155
MESH:D014605 Uveitis Cyclosporine 3.961336536
MESH:D054079 Vascular Malformations Tetrachlorodibenzodioxin 4.5712125929
MESH:D020246 Venous Thrombosis Ethinyl Estradiol 3.5014671159 15869587
MESH:D014820 Vitiligo Tretinoin 4.0216761959
MESH:D019282 Wasting Syndrome Tetrachlorodibenzodioxin 4.2215886252
MESH:D009396 Wilms Tumor Tretinoin 3.9316287080
MESH:D014985 Xerophthalmia Cyclosporine 4.4117120751
No data
Pharmacogenomics Knowledge Base Top
Drug Bank Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


Copyright © 2017, Center for Bioinformatics , Peking University | All Rights Reserved