AutismKB 2.0

Annotation Detail for CARKD


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Basic Information Top
Gene Symbol:CARKD ( FLJ10769,FLJ34548,FLJ52550,LP3298 )
Gene Full Name: carbohydrate kinase domain containing
Band: 13q34
Quick LinksEntrez ID:55739; OMIM: NA; Uniprot ID:CARKD_HUMAN; ENSEMBL ID: ENSG00000213995; HGNC ID:
Relate to Another Database: SFARIGene; denovo-db
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Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
D000082 Acetaminophen Acetaminophen affects the expression of CARKD mRNAaffects expression 17562736
D020122 tert-Butylhydroperoxide tert-Butylhydroperoxide results in decreased expression of CARKD mRNAdecreases expression 15336504
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000799 Angioedema Acetaminophen 4.9110982225
MESH:D001321 Autistic Disorder Acetaminophen 1.3918445737
MESH:D006528 Carcinoma, Hepatocellular Acetaminophen 1.413084413
MESH:D002386 Cataract Acetaminophen 2.8310977129
MESH:D056486 Drug-Induced Liver Injury Acetaminophen 1.6812958197 10774834 12705907 12594235 19739265 2444490 11421492 16109766 17522070 11739529 19416960 19370779 11461765 16081117 16781746 19420014 14725611 16393943 19085960 16177239 16227642 15619225 11834606 12392966 15968718 19923254 14986274 19164858 11529661 16485898 12540782 17562736 18713872 11743745 14550746 18071297 10915739 17906064 11287661 12153990 10663392
MESH:D056487 Drug-Induced Liver Injury, Chronic Acetaminophen 5.1719426721
MESH:D005756 Gastritis Acetaminophen 4.7416983495
MESH:D006930 Hyperalgesia Acetaminophen 3.1116870215
MESH:D007674 Kidney Diseases Acetaminophen 2.4415629191 12587719
MESH:D008107 Liver Diseases Acetaminophen 1.7119784758 11587558 16610002 16611625 12969438 12587719 19460945 19014921
MESH:D017114 Liver Failure, Acute Acetaminophen 3.7416871587 17185352
MESH:D008546 Melanoma, Experimental Acetaminophen 4.3319513568
MESH:D019636 Neurodegenerative Diseases Acetaminophen 3.3118514411
MESH:D010146 Pain Acetaminophen 2.8216870215
MESH:D012878 Skin Neoplasms tert-Butylhydroperoxide 2.878532709
MESH:D014581 Urticaria Acetaminophen 3.5810982225
No data
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  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018