AutismKB 2.0

Annotation Detail for OGDHL


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Basic Information Top
Gene Symbol:OGDHL ( - )
Gene Full Name: oxoglutarate dehydrogenase-like
Band: 10q11.23
Quick LinksEntrez ID:55753; OMIM: NA; Uniprot ID:OGDHL_HUMAN; ENSEMBL ID: ENSG00000197444; HGNC ID: 25590
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
Pathway IDPathway Name
PWY-5690TCA cycle variation III (eukaryotic)
Pathway IDPathway Name
hsa00310Lysine degradation
hsa00380Tryptophan metabolism
hsa00020Citrate cycle (TCA cycle)
hsa01100Metabolic pathways
No data
No data
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Related Diseases/Disorders Top
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
D016604 Aflatoxin B1 Aflatoxin B1 affects the expression of OGDHL proteinaffects expression 20106945
D016572 Cyclosporine Cyclosporine results in decreased expression of OGDHL mRNAdecreases expression 20106945
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D006528 Carcinoma, Hepatocellular Aflatoxin B1 1.9912907637 21507988 12619106
MESH:D002471 Cell Transformation, Neoplastic Cyclosporine 2.8512371664
MESH:D002779 Cholestasis Cyclosporine 3.2819486331
MESH:D005234 Fatty Liver Cyclosporine 3.4019224547
MESH:D005355 Fibrosis Cyclosporine 3.9012639820 12168785
MESH:D005885 Gingival Hyperplasia Cyclosporine 5.118708960
MESH:D006457 Hemoglobinuria, Paroxysmal Cyclosporine 5.3115720958
MESH:D006973 Hypertension Cyclosporine 2.2410903974
MESH:D007638 Keratoconjunctivitis Sicca Cyclosporine 5.5115604871
MESH:D007674 Kidney Diseases Cyclosporine 2.5818776723 10903974 8314463
MESH:D007680 Kidney Neoplasms Cyclosporine 3.1712371664
MESH:D008113 Liver Neoplasms Aflatoxin B1 2.4915890375 2125692 9163691 18177683
MESH:D008114 Liver Neoplasms, Experimental Aflatoxin B1 3.018603461
MESH:D008175 Lung Neoplasms Aflatoxin B1 1.8814755239
MESH:D008664 Metal Metabolism, Inborn Errors Cyclosporine 5.8616801185
MESH:D009402 Nephrosis, Lipoid Cyclosporine 5.5117954296
MESH:D009404 Nephrotic Syndrome Cyclosporine 3.7519348381 18481113
MESH:D011230 Precancerous Conditions Cyclosporine 3.6912371664
MESH:D011565 Psoriasis Cyclosporine 2.3516882103
MESH:D014605 Uveitis Cyclosporine 5.051336536
MESH:D014985 Xerophthalmia Cyclosporine 5.5117120751
Pathway ID Pathway Name
KEGG:00020 Citrate cycle (TCA cycle)
KEGG:00310 Lysine degradation
KEGG:01100 Metabolic pathways
KEGG:00380 Tryptophan metabolism
Pharmacogenomics Knowledge Base Top
Drug Bank Top

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Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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