AutismKB 2.0

Annotation Detail for EXOC1


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Basic Information Top
Gene Symbol:EXOC1 ( BM-102,FLJ10893,SEC3,SEC3L1,SEC3P )
Gene Full Name: exocyst complex component 1
Band: 4q12
Quick LinksEntrez ID:55763; OMIM: 607879; Uniprot ID:EXOC1_HUMAN; ENSEMBL ID: ENSG00000090989; HGNC ID: 30380
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
No data
No data
Pathway IDPathway Name
Diabetes pathways
Pathway IDPathway Name
200012Insulin Pathway
200046Arf6 trafficking events
No data
No data
Related Diseases/Disorders Top
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
D000082 Acetaminophen Acetaminophen affects the expression of EXOC1 mRNAaffects expression 17562736
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000799 Angioedema Acetaminophen 5.2610982225
MESH:D001321 Autistic Disorder Acetaminophen 1.3918445737
MESH:D006528 Carcinoma, Hepatocellular Acetaminophen 1.413084413
MESH:D002386 Cataract Acetaminophen 2.8610977129
MESH:D056486 Drug-Induced Liver Injury Acetaminophen 1.6911461765 19923254 16781746 16393943 19416960 19420014 11739529 12594235 14725611 10663392 18713872 12153990 11743745 19164858 11834606 17562736 16081117 10774834 14986274 11529661 16109766 12540782 16227642 14550746 12958197 2444490 19739265 19370779 10915739 11421492 11287661 12392966 17906064 15619225 19085960 16485898 15968718 17522070 18071297 16177239 12705907
MESH:D056487 Drug-Induced Liver Injury, Chronic Acetaminophen 5.5119426721
MESH:D005756 Gastritis Acetaminophen 5.0916983495
MESH:D006930 Hyperalgesia Acetaminophen 3.1516870215
MESH:D007674 Kidney Diseases Acetaminophen 2.4715629191 12587719
MESH:D008107 Liver Diseases Acetaminophen 1.7219784758 12587719 12969438 16611625 19460945 11587558 16610002 19014921
MESH:D017114 Liver Failure, Acute Acetaminophen 3.8116871587 17185352
MESH:D008546 Melanoma, Experimental Acetaminophen 4.4719513568
MESH:D019636 Neurodegenerative Diseases Acetaminophen 3.3618514411
MESH:D010146 Pain Acetaminophen 2.8716870215
MESH:D014581 Urticaria Acetaminophen 3.6710982225
Pathway ID Pathway Name
REACT:15380 Diabetes pathways
Pharmacogenomics Knowledge Base Top
  • PharmGKB Accession:PA134891660
  • No data
    No data
    Releated drug ID Related drug Name
    PA448976choline
    Drug Bank Top

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      (e.g. CHD8)

    Syndromic Genes

    Non-syndromic Genes

    AutismKB Statistics

    • Studies: 1,036
    • Genes: 1,379
    • CNVs/SVs: 5,420
    • SNVs/Indels: 11,669
    • de novo Mutations: 5,669
    • Mosaics: 789
    • Linkage Regions: 172
    • Paper Collected: 6/30/2018
    • Last Update: 8/26/2018