AutismKB 2.0

Annotation Detail for PRKCA


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Basic Information Top
Gene Symbol:PRKCA ( AAG6,MGC129900,MGC129901,PKC-alpha,PKCA,PRKACA )
Gene Full Name: protein kinase C, alpha
Band: 17q24.2
Quick LinksEntrez ID:5578; OMIM: 176960; Uniprot ID:KPCA_HUMAN; ENSEMBL ID: ENSG00000154229; HGNC ID: 9393
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
No data
Pathway IDPathway Name
hsa04670Leukocyte transendothelial migration
hsa04270Vascular smooth muscle contraction
hsa04912GnRH signaling pathway
hsa04916Melanogenesis
hsa04012ErbB signaling pathway
hsa04010MAPK signaling pathway
hsa04720Long-term potentiation
hsa04650Natural killer cell mediated cytotoxicity
hsa04020Calcium signaling pathway
hsa05146Amoebiasis
hsa04310Wnt signaling pathway
hsa04540Gap junction
hsa04730Long-term depression
hsa04970Salivary secretion
hsa04972Pancreatic secretion
hsa05130Pathogenic Escherichia coli infection
hsa04530Tight junction
hsa04960Aldosterone-regulated sodium reabsorption
hsa04971Gastric acid secretion
hsa05223Non-small cell lung cancer
hsa05214Glioma
hsa04510Focal adhesion
hsa04370VEGF signaling pathway
hsa05200Pathways in cancer
hsa04070Phosphatidylinositol signaling system
hsa04664Fc epsilon RI signaling pathway
hsa04666Fc gamma R-mediated phagocytosis
hsa05110Vibrio cholerae infection
Pathway IDPathway Name
Signaling by GPCR
Synaptic Transmission
Diabetes pathways
Signalling by NGF
Hemostasis
Opioid Signalling
Integration of energy metabolism
Pathway IDPathway Name
200184Downstream signaling in naive CD8+ T cells
200004Endothelins
200151VEGFR1 specific signals
200088Ras signaling in the CD4+ TCR pathway
200080mTOR signaling pathway
200069Thromboxane A2 receptor signaling
200142Retinoic acid receptors-mediated signaling
200062TCR signaling in naive CD8+ T cells
200076Role of Calcineurin-dependent NFAT signaling in lymphocytes
200162a6b1 and a6b4 Integrin signaling
200161Signaling events mediated by VEGFR1 and VEGFR2
200113ErbB1 downstream signaling
200116ATF-2 transcription factor network
200115Syndecan-4-mediated signaling events
200022TCR signaling in naive CD4+ T cells
200026Canonical NF-kappaB pathway
200058Signaling events regulated by Ret tyrosine kinase
Pathway IDPathway Name
P00003Alzheimer disease-amyloid secretase pathway
P04385Histamine H1 receptor mediated signaling pathway
P04391Oxytocin receptor mediated signaling pathway
P00056VEGF signaling pathway
P00019Endothelin signaling pathway
P00042Muscarinic acetylcholine receptor 1 and 3 signaling pathway
P00018EGF receptor signaling pathway
P04394Thyrotropin-releasing hormone receptor signaling pathway
P00005Angiogenesis
P043745HT2 type receptor mediated signaling pathway
P00002Alpha adrenergic receptor signaling pathway
P00047PDGF signaling pathway
P00006Apoptosis signaling pathway
P00021FGF signaling pathway
P00027Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway
P00057Wnt signaling pathway
Pathway IDPathway Name
500136Regulation of Insulin Secretion by Acetylcholine
Related Diseases/Disorders Top
No data
No data
Desease Name
multiple sclerosis
IMMUNE
No data
Desease Name
Pituitary tumor, invasive
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C025984 15-hydroxy-5,8,11,13-eicosatetraenoic acid 15-hydroxy-5,8,11,13-eicosatetraenoic acid affects the localization of PRKCA proteinaffects localization 15613483
C025984 15-hydroxy-5,8,11,13-eicosatetraenoic acid 15-hydroxy-5,8,11,13-eicosatetraenoic acid promotes the reaction [EGF protein affects the localization of PRKCA protein]affects localization|increases reaction 15613483
C025984 15-hydroxy-5,8,11,13-eicosatetraenoic acid 15-hydroxy-5,8,11,13-eicosatetraenoic acid promotes the reaction [HGF protein affects the localization of PRKCA protein]affects localization|increases reaction 15613483
C025984 15-hydroxy-5,8,11,13-eicosatetraenoic acid 15-hydroxy-5,8,11,13-eicosatetraenoic acid results in increased activity of PRKCA proteinincreases activity 15451026
C025984 15-hydroxy-5,8,11,13-eicosatetraenoic acid calphostin C inhibits the reaction [15-hydroxy-5,8,11,13-eicosatetraenoic acid results in increased activity of PRKCA protein]decreases reaction|increases activity 15451026
C060229 1-(6-((3-methoxyestra-1,3,5(10)-trien-17-yl)amino)hexyl)-1H-pyrrole-2,5-dione 1-(6-((3-methoxyestra-1,3,5(10)-trien-17-yl)amino)hexyl)-1H-pyrrole-2,5-dione promotes the reaction [Corticosterone results in increased activity of PRKCA protein]increases activity|increases reaction 16581232
C014024 2,4,5,2',4',5'-hexachlorobiphenyl 2,4,5,2',4',5'-hexachlorobiphenyl results in increased activity of PRKCA proteinincreases activity 16263226
C014024 2,4,5,2',4',5'-hexachlorobiphenyl 2,4,5,2',4',5'-hexachlorobiphenyl results in increased expression of PRKCA proteinincreases expression 16263226
C028451 3,4,3',4'-tetrachlorobiphenyl 3,4,3',4'-tetrachlorobiphenyl results in increased activity of PRKCA proteinincreases activity 16263226
C028451 3,4,3',4'-tetrachlorobiphenyl 3,4,3',4'-tetrachlorobiphenyl results in increased expression of PRKCA proteinincreases expression 16263226
C002385 3-morpholino-sydnonimine [3-morpholino-sydnonimine co-treated with Staurosporine] results in decreased expression of PRKCA proteinaffects cotreatment|decreases expression 11994256
C002385 3-morpholino-sydnonimine Staurosporine inhibits the reaction [3-morpholino-sydnonimine results in increased phosphorylation of PRKCA protein]decreases reaction|increases phosphorylation 11994256
C088860 4-((3-bromophenyl)amino)-6,7-dimethoxyquinazoline 4-((3-bromophenyl)amino)-6,7-dimethoxyquinazoline inhibits the reaction [EGF protein affects the localization of PRKCA protein]affects localization|decreases reaction 15613483
C035207 4-amino-2,6-dinitrotoluene 4-amino-2,6-dinitrotoluene affects the expression of PRKCA mRNAaffects expression 21346803
C059539 4'-N-benzoylstaurosporine 4'-N-benzoylstaurosporine results in decreased activity of PRKCA proteindecreases activity 15542774
C058206 6-chloro-3,5-diaminopyrazine-3-carboxamide 6-chloro-3,5-diaminopyrazine-3-carboxamide results in decreased expression of PRKCA proteindecreases expression 12225976
D000255 Adenosine Triphosphate [[Adenosine Triphosphate co-treated with PRKCA protein] results in increased phosphorylation of RALBP1 protein] which results in increased transport of Doxorubicinaffects cotreatment|increases phosphorylation|increases transport 16087181
C096920 AGN 193109 AGN 193109 inhibits the reaction [Tretinoin results in increased expression of PRKCA mRNA]decreases reaction|increases expression 16505366
D000450 Aldosterone Aldosterone results in decreased expression of PRKCA proteindecreases expression 12225976
D000643 Ammonium Chloride Ammonium Chloride affects the expression of PRKCA mRNAaffects expression 16483693
D000643 Ammonium Chloride Ammonium Chloride results in decreased expression of PRKCA proteindecreases expression 16483693
D000661 Amphetamine Amphetamine results in increased expression of PRKCA mRNAincreases expression 16101753
D000661 Amphetamine PRKCA protein promotes the reaction [Amphetamine results in decreased expression of NPY mRNA]decreases expression|increases reaction 16101753
D000661 Amphetamine PRKCA protein results in increased susceptibility to Amphetamineincreases response to substance 16101753
C028617 aroclor 1248 aroclor 1248 results in increased activity of PRKCA proteinincreases activity 16263226
C028617 aroclor 1248 aroclor 1248 results in increased expression of PRKCA proteinincreases expression 16263226
C028617 aroclor 1248 aroclor 1248 results in increased transport of PRKCA proteinincreases transport 16263226
D017638 Asbestos, Crocidolite Asbestos, Crocidolite results in increased activity of PRKCA proteinincreases activity 12626342
D017638 Asbestos, Crocidolite Asbestos, Crocidolite results in increased expression of PRKCA proteinincreases expression 12626342
D001280 Atrazine Atrazine results in increased expression of PRKCA mRNAincreases expression 18585445
D001564 Benzo(a)pyrene Benzo(a)pyrene results in decreased expression of PRKCA mRNAdecreases expression 20064835
20106945
D015123 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in decreased expression of PRKCA mRNAdecreases expression 19150397
C477843 bicyclol bicyclol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PRKCA mRNA]decreases reaction|increases expression 17106253
C477843 bicyclol bicyclol inhibits the reaction [Diethylnitrosamine results in increased expression of PRKCA mRNA]decreases reaction|increases expression 17106253
D001647 Bile Acids and Salts Bile Acids and Salts promotes the reaction [PRKCA protein results in increased phosphorylation of ABCB11 protein]increases phosphorylation|increases reaction 11343252
D020001 1-Butanol [1-Butanol inhibits the reaction [PRKCA protein binds to PLD1 protein]] which results in decreased activity of PLD1 proteinaffects binding|decreases activity|decreases reaction 15652502
D020001 1-Butanol 1-Butanol inhibits the reaction [Thapsigargin results in increased localization of PRKCA protein]decreases reaction|increases localization 15843515
D002084 Butylated Hydroxytoluene Butylated Hydroxytoluene results in decreased expression of PRKCA proteindecreases expression 7716780
D020122 tert-Butylhydroperoxide tert-Butylhydroperoxide results in decreased expression of PRKCA mRNAdecreases expression 15336504
D020122 tert-Butylhydroperoxide tert-Butylhydroperoxide affects the localization of PRKCA proteinaffects localization 16716901
D020122 tert-Butylhydroperoxide tert-Butylhydroperoxide results in increased activity of PRKCA proteinincreases activity 16716901
D002101 Cacodylic Acid Cacodylic Acid results in increased expression of PRKCA mRNAincreases expression 17481689
D002118 Calcium [Tretinoin co-treated with Calcium] results in increased activity of PRKCA proteinaffects cotreatment|increases activity 16114872
C058819 calphostin C calphostin C inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of PRKCA protein]decreases reaction|increases activity 16091123
C058819 calphostin C calphostin C inhibits the reaction [15-hydroxy-5,8,11,13-eicosatetraenoic acid results in increased activity of PRKCA protein]decreases reaction|increases activity 15451026
C058819 calphostin C calphostin C inhibits the reaction [Tetradecanoylphorbol Acetate affects the localization of PRKCA protein]affects localization|decreases reaction 16343552
C058819 calphostin C calphostin C inhibits the reaction [Heptachlor affects the localization of PRKCA protein]affects localization|decreases reaction 14678745
C058819 calphostin C calphostin C inhibits the reaction [Tetradecanoylphorbol Acetate affects the localization of PRKCA protein]affects localization|decreases reaction 14678745
D002211 Capsaicin Capsaicin results in increased expression of PRKCA mRNAincreases expression 18752301
D002211 Capsaicin Capsaicin results in increased expression of PRKCA proteinincreases expression 18752301
D002211 Capsaicin chelerythrine inhibits the reaction [Capsaicin results in increased expression of PRKCA protein]decreases reaction|increases expression 18752301
D002211 Capsaicin iodoresiniferatoxin inhibits the reaction [Capsaicin results in increased expression of PRKCA protein]decreases reaction|increases expression 18752301
C016299 chelerythrine chelerythrine inhibits the reaction [Capsaicin results in increased expression of PRKCA protein]decreases reaction|increases expression 18752301
D003345 Corticosterone 1-(6-((3-methoxyestra-1,3,5(10)-trien-17-yl)amino)hexyl)-1H-pyrrole-2,5-dione promotes the reaction [Corticosterone results in increased activity of PRKCA protein]increases activity|increases reaction 16581232
D003345 Corticosterone PD 98059 promotes the reaction [Corticosterone results in increased activity of PRKCA protein]increases activity|increases reaction 16581232
D003474 Curcumin [PRKCA protein results in increased phosphorylation of CFTR protein] promotes the reaction [Curcumin results in increased activity of CFTR protein]increases activity|increases phosphorylation|increases reaction 17178710
C004742 daidzein daidzein results in increased activity of PRKCA proteinincreases activity 16972265
D003840 Deoxycholic Acid [gluconic acid co-treated with Deoxycholic Acid] results in increased expression of PRKCA mRNAaffects cotreatment|increases expression 16556975
D003907 Dexamethasone Dexamethasone affects the expression of PRKCA mRNAaffects expression 12732289
D004041 Dietary Fats Dietary Fats results in decreased expression of PRKCA mRNAdecreases expression 18042831
D004052 Diethylnitrosamine Diethylnitrosamine results in increased phosphorylation of and results in increased activity of PRKCA proteinincreases activity|increases phosphorylation 17942915
D004052 Diethylnitrosamine MET protein inhibits the reaction [Diethylnitrosamine results in increased phosphorylation of and results in increased activity of PRKCA protein]decreases reaction|increases activity|increases phosphorylation 17942915
D004052 Diethylnitrosamine bicyclol inhibits the reaction [Diethylnitrosamine results in increased expression of PRKCA mRNA]decreases reaction|increases expression 17106253
D004052 Diethylnitrosamine Diethylnitrosamine results in increased expression of PRKCA mRNAincreases expression 17106253
D004054 Diethylstilbestrol Diethylstilbestrol results in decreased expression of PRKCAdecreases expression 17943652
D004075 Diglycerides Diglycerides affects the reaction [Phenylephrine results in increased localization of PRKCA protein]affects reaction|increases localization 18487437
C472511 dimethylarsinous acid dimethylarsinous acid results in decreased expression of PRKCA mRNAdecreases expression 16507463
D004317 Doxorubicin [[Adenosine Triphosphate co-treated with PRKCA protein] results in increased phosphorylation of RALBP1 protein] which results in increased transport of Doxorubicinaffects cotreatment|increases phosphorylation|increases transport 16087181
D004317 Doxorubicin PRKCA protein affects the reaction [RALBP1 protein affects the transport of and affects the susceptibility to Doxorubicin]affects reaction|affects response to substance|affects transport 16579994
D004958 Estradiol [Estradiol co-treated with Tetrachlorodibenzodioxin] results in decreased expression of PRKCA mRNAaffects cotreatment|decreases expression 19619570
D004958 Estradiol Estradiol results in increased expression of PRKCA mRNAincreases expression 19619570
D000431 Ethanol [Ethanol results in increased localization of and results in increased activity of PRKCA protein] promotes the reaction [Tetradecanoylphorbol Acetate results in increased abundance of Superoxides]increases abundance|increases activity|increases localization|increases reaction 10651808
D004997 Ethinyl Estradiol Ethinyl Estradiol affects the expression of PRKCA mRNAaffects expression 17555576
C049347 fasudil fasudil results in decreased activity of PRKCA proteindecreases activity 17222050
C065382 fluticasone fluticasone results in decreased expression of PRKCA proteindecreases expression 15634547
D019833 Genistein Genistein results in increased expression of PRKCA mRNAincreases expression 16705744
C030691 gluconic acid [gluconic acid co-treated with Deoxycholic Acid] results in increased expression of PRKCA mRNAaffects cotreatment|increases expression 16556975
C081021 Go 6976 Go 6976 results in decreased expression of and results in decreased activity of PRKCA proteindecreases activity|decreases expression 16374459
C081021 Go 6976 Go 6976 results in decreased expression of PRKCA mRNAdecreases expression 16374459
C081021 Go 6976 Go 6976 results in decreased phosphorylation of PRKCA proteindecreases phosphorylation 19393235
C081021 Go 6976 Go 6976 results in decreased activity of PRKCA proteindecreases activity 15767308
D019307 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine inhibits the reaction [Heptachlor affects the localization of PRKCA protein]affects localization|decreases reaction 14678745
D019307 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine inhibits the reaction [Tetradecanoylphorbol Acetate affects the localization of PRKCA protein]affects localization|decreases reaction 14678745
D006533 Heptachlor 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine inhibits the reaction [Heptachlor affects the localization of PRKCA protein]affects localization|decreases reaction 14678745
D006533 Heptachlor calphostin C inhibits the reaction [Heptachlor affects the localization of PRKCA protein]affects localization|decreases reaction 14678745
D006533 Heptachlor Heptachlor affects the localization of and results in increased activity of PRKCA proteinaffects localization|increases activity 14678745
D006533 Heptachlor Staurosporine inhibits the reaction [Heptachlor affects the localization of PRKCA protein]affects localization|decreases reaction 14678745
D006861 Hydrogen Peroxide Hydrogen Peroxide results in increased activity of PRKCA proteinincreases activity 12626342
D006861 Hydrogen Peroxide Hydrogen Peroxide results in increased expression of PRKCA proteinincreases expression 12626342
D006861 Hydrogen Peroxide [Hydrogen Peroxide co-treated with Vanadates] results in increased phosphorylation of [PLD1 protein binds to PRKCA protein]affects binding|affects cotreatment|increases phosphorylation 15150437
D006861 Hydrogen Peroxide [Hydrogen Peroxide co-treated with Vanadates] results in increased phosphorylation of PRKCA proteinaffects cotreatment|increases phosphorylation 15150437
C078006 imidaprilat imidaprilat inhibits the reaction [AGT protein results in increased activity of and results in increased localization of PRKCA protein]decreases reaction|increases activity|increases localization 16257180
C468130 iodoresiniferatoxin iodoresiniferatoxin inhibits the reaction [Capsaicin results in increased expression of PRKCA protein]decreases reaction|increases expression 18752301
C051890 irinotecan irinotecan metabolite results in increased phosphorylation of PRKCA proteinincreases phosphorylation 15723263
C051890 irinotecan irinotecan results in increased phosphorylation of PRKCA proteinincreases phosphorylation 15723263
C037642 kemptide PRKCA protein results in increased metabolism of kemptideincreases metabolic processing 17222050
C063302 KN 62 KN 62 results in decreased activity of PRKCA proteindecreases activity 17222050
D007854 Lead Lead results in decreased expression of PRKCA proteindecreases expression 16547843
C008261 lead acetate lead acetate results in decreased expression of PRKCA proteindecreases expression 16547843
D008070 Lipopolysaccharides Lipopolysaccharides affects the localization of and results in increased activity of PRKCA proteinaffects localization|increases activity 16330529
C008493 methylselenic acid methylselenic acid results in increased expression of PRKCA mRNAincreases expression 12517777
D015741 Metribolone Metribolone promotes the reaction [EZR protein binds to PRKCA protein]affects binding|increases reaction 16873375
D015741 Metribolone PRKCA protein affects the reaction [Metribolone results in increased phosphorylation of EZR protein]affects reaction|increases phosphorylation 16873375
D015735 Mifepristone Mifepristone binds to and results in decreased activity of PRKCA proteinaffects binding|decreases activity 16581232
C020300 monomethylarsonic acid monomethylarsonic acid results in increased expression of PRKCA mRNAincreases expression 17481689
C406082 monomethylarsonous acid monomethylarsonous acid results in decreased expression of PRKCA mRNAdecreases expression 16507463
C063509 N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide results in decreased activity of PRKCA proteindecreases activity 16361081
C063509 N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide results in decreased activity of PRKCA proteindecreases activity 17222050
C041786 palm oil palm oil results in decreased expression of PRKCA mRNAdecreases expression 18042831
C093973 PD 98059 PD 98059 inhibits the reaction [EGF protein affects the localization of PRKCA protein]affects localization|decreases reaction 15613483
C093973 PD 98059 PD 98059 inhibits the reaction [HGF protein affects the localization of PRKCA protein]affects localization|decreases reaction 15613483
C093973 PD 98059 PD 98059 promotes the reaction [Corticosterone results in increased activity of PRKCA protein]increases activity|increases reaction 16581232
D010634 Phenobarbital Phenobarbital affects the expression of PRKCA mRNAaffects expression 19136022
D010656 Phenylephrine DGKE protein inhibits the reaction [Phenylephrine results in increased localization of PRKCA protein]decreases reaction|increases localization 18487437
D010656 Phenylephrine Diglycerides affects the reaction [Phenylephrine results in increased localization of PRKCA protein]affects reaction|increases localization 18487437
D010656 Phenylephrine Phenylephrine results in increased localization of PRKCA proteinincreases localization 18487437
D010656 Phenylephrine GLRX3 protein inhibits the reaction [Phenylephrine results in increased phosphorylation of and results in increased activity of PRKCA protein]decreases reaction|increases activity|increases phosphorylation 16809552
D010656 Phenylephrine Phenylephrine results in increased activity of PRKCA proteinincreases activity 12435817
D010656 Phenylephrine Phenylephrine results in increased phosphorylation of and results in increased activity of PRKCA proteinincreases activity|increases phosphorylation 16809552
D015240 Phorbol 12,13-Dibutyrate Phorbol 12,13-Dibutyrate results in decreased expression of PRKCA proteindecreases expression 17171646
D015240 Phorbol 12,13-Dibutyrate Phorbol 12,13-Dibutyrate results in increased expression of PRKCA proteinincreases expression 12626342
D010703 Phorbol Esters Phorbol Esters promotes the reaction [PRKCA protein results in increased phosphorylation of ABCB11 protein]increases phosphorylation|increases reaction 11343252
D010703 Phorbol Esters Phorbol Esters affects the localization of and results in increased activity of PRKCA proteinaffects localization|increases activity 14679204
D010718 Phosphatidylserines [Tretinoin co-treated with Phosphatidylserines] results in decreased activity of PRKCA proteinaffects cotreatment|decreases activity 16114872
C006253 pirinixic acid pirinixic acid affects the expression of PRKCA mRNAaffects expression 19136022
C006253 pirinixic acid pirinixic acid results in increased expression of PRKCA mRNAincreases expression 12832660
D011280 Pregnanolone Pregnanolone results in decreased expression of PRKCA proteindecreases expression 16581232
D019269 Phosphatidylinositol 4,5-Diphosphate [Tretinoin co-treated with Phosphatidylinositol 4,5-Diphosphate] results in decreased activity of PRKCA proteinaffects cotreatment|decreases activity 16114872
C059514 resveratrol PRKCA protein affects the reaction [EGF protein inhibits the reaction [resveratrol results in increased phosphorylation of and results in increased activity of and results in increased localization of MAPK1 protein]]affects reaction|decreases reaction|increases activity|increases localization|increases phosphorylation 15542774
C059514 resveratrol PRKCA protein affects the reaction [EGF protein inhibits the reaction [resveratrol results in increased phosphorylation of and results in increased activity of and results in increased localization of MAPK3 protein]]affects reaction|decreases reaction|increases activity|increases localization|increases phosphorylation 15542774
C059514 resveratrol PRKCA protein affects the reaction [EGF protein inhibits the reaction [resveratrol results in increased phosphorylation of and results in increased activity of and results in increased localization of TP53 protein]]affects reaction|decreases reaction|increases activity|increases localization|increases phosphorylation 15542774
C089730 rosiglitazone rosiglitazone inhibits the reaction [Tetradecanoylphorbol Acetate affects the localization of PRKCA protein]affects localization|decreases reaction 20032081
C089730 rosiglitazone rosiglitazone inhibits the reaction [VEGFA protein affects the localization of PRKCA protein]affects localization|decreases reaction 20032081
C085746 rottlerin rottlerin results in decreased activity of PRKCA proteindecreases activity 17222050
C017947 sodium arsenite sodium arsenite results in decreased expression of PRKCA mRNAdecreases expression 16507463
C017947 sodium arsenite sodium arsenite results in increased expression of PRKCA mRNAincreases expression 12016162
D019311 Staurosporine Staurosporine affects the localization of and affects the activity of PRKCA proteinaffects activity|affects localization 16225760
D019311 Staurosporine [3-morpholino-sydnonimine co-treated with Staurosporine] results in decreased expression of PRKCA proteinaffects cotreatment|decreases expression 11994256
D019311 Staurosporine Staurosporine inhibits the reaction [3-morpholino-sydnonimine results in increased phosphorylation of PRKCA protein]decreases reaction|increases phosphorylation 11994256
D019311 Staurosporine Staurosporine inhibits the reaction [Heptachlor affects the localization of PRKCA protein]affects localization|decreases reaction 14678745
D019311 Staurosporine Staurosporine inhibits the reaction [Tetradecanoylphorbol Acetate affects the localization of PRKCA protein]affects localization|decreases reaction 14678745
D013481 Superoxides [Ethanol results in increased localization of and results in increased activity of PRKCA protein] promotes the reaction [Tetradecanoylphorbol Acetate results in increased abundance of Superoxides]increases abundance|increases activity|increases localization|increases reaction 10651808
D013629 Tamoxifen Tamoxifen affects the expression of PRKCA mRNAaffects expression 17555576
D013629 Tamoxifen Tamoxifen results in decreased phosphorylation of PRKCA proteindecreases phosphorylation 19393235
D020002 tert-Butyl Alcohol tert-Butyl Alcohol inhibits the reaction [Thapsigargin results in increased localization of PRKCA protein]decreases reaction|increases localization 15843515
D013749 Tetrachlorodibenzodioxin [Estradiol co-treated with Tetrachlorodibenzodioxin] results in decreased expression of PRKCA mRNAaffects cotreatment|decreases expression 19619570
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in decreased expression of PRKCA mRNAdecreases expression 19684285
19619570
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in increased expression of PRKCA mRNAincreases expression 12377990
19684285
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in decreased expression of PRKCAdecreases expression 17943652
D013749 Tetrachlorodibenzodioxin [Tetrachlorodibenzodioxin binds to AHR protein] which affects the localization of PRKCA proteinaffects binding|affects localization 15761253
C117155 tetracycline CMT-3 tetracycline CMT-3 results in decreased activity of PRKCA proteindecreases activity 16134060
D013755 Tetradecanoylphorbol Acetate calphostin C inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of PRKCA protein]decreases reaction|increases activity 16091123
D013755 Tetradecanoylphorbol Acetate [Ethanol results in increased localization of and results in increased activity of PRKCA protein] promotes the reaction [Tetradecanoylphorbol Acetate results in increased abundance of Superoxides]increases abundance|increases activity|increases localization|increases reaction 10651808
D013755 Tetradecanoylphorbol Acetate rosiglitazone inhibits the reaction [Tetradecanoylphorbol Acetate affects the localization of PRKCA protein]affects localization|decreases reaction 20032081
D013755 Tetradecanoylphorbol Acetate Tetradecanoylphorbol Acetate affects the localization of and results in increased activity of PRKCA proteinaffects localization|increases activity 16091123
15978937
D013755 Tetradecanoylphorbol Acetate Tetradecanoylphorbol Acetate affects the localization of PRKCA proteinaffects localization 20032081
15976015
D013755 Tetradecanoylphorbol Acetate Tetradecanoylphorbol Acetate results in decreased expression of PRKCA proteindecreases expression 17171646
D013755 Tetradecanoylphorbol Acetate Tetradecanoylphorbol Acetate results in decreased phosphorylation of PRKCA proteindecreases phosphorylation 15380616
D013755 Tetradecanoylphorbol Acetate bicyclol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PRKCA mRNA]decreases reaction|increases expression 17106253
D013755 Tetradecanoylphorbol Acetate calphostin C inhibits the reaction [Tetradecanoylphorbol Acetate affects the localization of PRKCA protein]affects localization|decreases reaction 16343552
D013755 Tetradecanoylphorbol Acetate Tetradecanoylphorbol Acetate affects the localization of PRKCA proteinaffects localization 16343552
D013755 Tetradecanoylphorbol Acetate Tetradecanoylphorbol Acetate results in increased expression of PRKCA mRNAincreases expression 17106253
D013755 Tetradecanoylphorbol Acetate Tetradecanoylphorbol Acetate results in increased localization of PRKCA proteinincreases localization 10656618
D013755 Tetradecanoylphorbol Acetate 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine inhibits the reaction [Tetradecanoylphorbol Acetate affects the localization of PRKCA protein]affects localization|decreases reaction 14678745
D013755 Tetradecanoylphorbol Acetate calphostin C inhibits the reaction [Tetradecanoylphorbol Acetate affects the localization of PRKCA protein]affects localization|decreases reaction 14678745
D013755 Tetradecanoylphorbol Acetate Staurosporine inhibits the reaction [Tetradecanoylphorbol Acetate affects the localization of PRKCA protein]affects localization|decreases reaction 14678745
D013755 Tetradecanoylphorbol Acetate Tetradecanoylphorbol Acetate affects the localization of PRKCA proteinaffects localization 14678745
14975926
12720544
14736339
D013755 Tetradecanoylphorbol Acetate Tetradecanoylphorbol Acetate results in increased localization of PRKCA proteinincreases localization 15843515
D019284 Thapsigargin 1-Butanol inhibits the reaction [Thapsigargin results in increased localization of PRKCA protein]decreases reaction|increases localization 15843515
D019284 Thapsigargin tert-Butyl Alcohol inhibits the reaction [Thapsigargin results in increased localization of PRKCA protein]decreases reaction|increases localization 15843515
D019284 Thapsigargin Thapsigargin results in increased localization of PRKCA proteinincreases localization 15843515
D013893 Thiram Thiram results in decreased activity of PRKCA proteindecreases activity 15998240
C080287 thymeleatoxin thymeleatoxin affects the localization of PRKCA proteinaffects localization 14679204
D014212 Tretinoin PRKCA protein affects the reaction [Tretinoin results in increased activity of STS protein]affects reaction|increases activity 16178010
D014212 Tretinoin AGN 193109 inhibits the reaction [Tretinoin results in increased expression of PRKCA mRNA]decreases reaction|increases expression 16505366
D014212 Tretinoin Tretinoin results in increased expression of PRKCA mRNAincreases expression 16505366
D014212 Tretinoin [Tretinoin co-treated with Calcium] results in increased activity of PRKCA proteinaffects cotreatment|increases activity 16114872
D014212 Tretinoin [Tretinoin co-treated with Phosphatidylinositol 4,5-Diphosphate] results in decreased activity of PRKCA proteinaffects cotreatment|decreases activity 16114872
D014212 Tretinoin [Tretinoin co-treated with Phosphatidylserines] results in decreased activity of PRKCA proteinaffects cotreatment|decreases activity 16114872
C052920 trimethylarsine oxide trimethylarsine oxide results in increased expression of PRKCA mRNAincreases expression 17481689
D014415 Tunicamycin Tunicamycin results in increased expression of PRKCA mRNAincreases expression 17127020
D014520 Urethane IFNG protein inhibits the reaction [Urethane results in decreased expression of PRKCA mRNA]decreases expression|decreases reaction 11091364
D014520 Urethane Urethane results in decreased expression of PRKCA mRNAdecreases expression 11091364
D014635 Valproic Acid Valproic Acid results in increased expression of PRKCA mRNAincreases expression 19101580
D014635 Valproic Acid Valproic Acid results in decreased expression of PRKCA proteindecreases expression 15249158
D014638 Vanadates [Hydrogen Peroxide co-treated with Vanadates] results in increased phosphorylation of [PLD1 protein binds to PRKCA protein]affects binding|affects cotreatment|increases phosphorylation 15150437
D014638 Vanadates [Hydrogen Peroxide co-treated with Vanadates] results in increased phosphorylation of PRKCA proteinaffects cotreatment|increases phosphorylation 15150437
D014639 Vanadium PRKCA protein affects the reaction [Vanadium results in increased phosphorylation of and results in increased activity of AKT1 protein]affects reaction|increases activity|increases phosphorylation 14971662
D014639 Vanadium PRKCA protein affects the reaction [Vanadium results in increased phosphorylation of and results in increased activity of RPS6KB1 protein]affects reaction|increases activity|increases phosphorylation 14971662
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000008 Abdominal Neoplasms Tamoxifen 3.6814745880
MESH:D000014 Abnormalities, Drug-Induced 4-amino-2,6-dinitrotoluene 22.417525203
MESH:D000014 Abnormalities, Drug-Induced Capsaicin 22.4118926900
MESH:D000014 Abnormalities, Drug-Induced Ethanol 22.4117676605 18926900
MESH:D000014 Abnormalities, Drug-Induced Phenobarbital 22.416195326
MESH:D000014 Abnormalities, Drug-Induced Tetrachlorodibenzodioxin 22.4111752688 14514962 15322242
MESH:D000014 Abnormalities, Drug-Induced Valproic Acid 22.418875741
MESH:D000015 Abnormalities, Multiple Valproic Acid 3.1619490988
MESH:D000138 Acidosis Ammonium Chloride 7.6718287403
MESH:D000138 Acidosis Ethanol 7.6711192467
MESH:D000152 Acne Vulgaris Ethinyl Estradiol 3.0817505938
MESH:D058186 Acute Kidney Injury Capsaicin 10.3418460982
MESH:D058186 Acute Kidney Injury resveratrol 10.3416538975
MESH:D058186 Acute Kidney Injury Superoxides 10.3418460982
MESH:D055371 Acute Lung Injury Lipopolysaccharides 6.4318653653 11850527
MESH:D055371 Acute Lung Injury pirinixic acid 6.4318653653
MESH:D000230 Adenocarcinoma Benzo(a)pyrene 15.9320127859 20464547
MESH:D000230 Adenocarcinoma daidzein 15.9311473722
MESH:D000230 Adenocarcinoma Doxorubicin 15.9317418594
MESH:D000230 Adenocarcinoma Estradiol 15.9311473722
MESH:D000230 Adenocarcinoma Ethinyl Estradiol 15.9314692618
MESH:D000230 Adenocarcinoma Genistein 15.9311473722
MESH:D000230 Adenocarcinoma Urethane 15.9318316556
MESH:D002282 Adenocarcinoma, Bronchiolo-Alveolar Urethane 4.8515814487
MESH:D000236 Adenoma Benzo(a)pyrene 11.386695378
MESH:D000236 Adenoma Diethylnitrosamine 11.3810737359 6695378
MESH:D000236 Adenoma resveratrol 11.3815688382
MESH:D000236 Adenoma Urethane 11.3810530776 10822126 17195641 6695378 17093202 16926031 11497255
MESH:D018248 Adenoma, Liver Cell Diethylnitrosamine 17.9819061943 17162532 19052882 16434500 17620307 18056438
MESH:D018248 Adenoma, Liver Cell Phenobarbital 17.9817620307
MESH:D018248 Adenoma, Liver Cell pirinixic acid 17.9816434500
MESH:D018248 Adenoma, Liver Cell Tetrachlorodibenzodioxin 17.9816835633
MESH:D000310 Adrenal Gland Neoplasms sodium arsenite 3.8415276417
MESH:D018246 Adrenocortical Adenoma sodium arsenite 4.0416712894 17306315
MESH:D000382 Agricultural Workers' Diseases Atrazine 6.6711874814
MESH:D000382 Agricultural Workers' Diseases Heptachlor 6.6712661182
MESH:D000419 Albuminuria Doxorubicin 3.7321441931
MESH:D020268 Alcohol-Induced Disorders, Nervous System Ethanol 4.4515451039 15451040
MESH:D019973 Alcohol-Related Disorders Curcumin 4.2217887948
MESH:D000505 Alopecia Capsaicin 7.2417569567
MESH:D000505 Alopecia Tretinoin 7.2415955085
MESH:D000544 Alzheimer Disease Curcumin 5.0715590663
MESH:D000544 Alzheimer Disease resveratrol 5.0716162502 16183991
MESH:D000544 Alzheimer Disease rosiglitazone 5.0719621015
MESH:D000550 Amblyopia Valproic Acid 4.3717688650
MESH:D019969 Amphetamine-Related Disorders Amphetamine 5.2116459022 16916582 18475255 15010207
MESH:D000686 Amyloidosis Diethylstilbestrol 3.6715469931
MESH:D000740 Anemia Tetrachlorodibenzodioxin 2.2011748828
MESH:D000756 Anemia, Sideroblastic Superoxides 4.8516910769
MESH:D000853 Anophthalmos Ethanol 3.9915513904
MESH:D000855 Anorexia Amphetamine 4.2612005258 16101753 16084549 12183048
MESH:D001008 Anxiety Disorders Ethanol 6.6611141031
MESH:D001008 Anxiety Disorders Valproic Acid 6.6617497229
MESH:D017544 Aortic Aneurysm, Abdominal Benzo(a)pyrene 3.2419183758
MESH:D001145 Arrhythmias, Cardiac Phenylephrine 3.3717460149
MESH:D001161 Arteriosclerosis Dietary Fats 7.1715238619
MESH:D001161 Arteriosclerosis Ethinyl Estradiol 7.1711256880
MESH:D001169 Arthritis, Experimental Dexamethasone 12.6917659584
MESH:D001169 Arthritis, Experimental Ethinyl Estradiol 12.6915885639
MESH:D001169 Arthritis, Experimental resveratrol 12.6917115116
MESH:D001169 Arthritis, Experimental Tretinoin 12.6916412693
MESH:D001172 Arthritis, Rheumatoid Curcumin 3.7416807698
MESH:D001172 Arthritis, Rheumatoid Tretinoin 3.7416292516
MESH:D001249 Asthma fluticasone 4.4311596838 11991558 11101185
MESH:D001249 Asthma Tretinoin 4.4316456186
MESH:D001259 Ataxia 1-Butanol 4.797820390
MESH:D050197 Atherosclerosis Curcumin 5.0218704882
MESH:D050197 Atherosclerosis resveratrol 5.0216873680 17967414
MESH:D001321 Autistic Disorder Valproic Acid 2.1820603192 18775368 15238991 17157402 18316065 19460635 17507914 16609825 18558336 19232924 17688650 18396377 18940202 18177632 18985861
MESH:D001327 Autoimmune Diseases Curcumin 3.6719761891
MESH:D001471 Barrett Esophagus Tretinoin 3.5916935849
MESH:D001714 Bipolar Disorder Valproic Acid 2.5717594078 20046352
MESH:D001778 Blood Coagulation Disorders pirinixic acid 10.8319483382
MESH:D001778 Blood Coagulation Disorders Tetrachlorodibenzodioxin 10.8312125929
MESH:D001778 Blood Coagulation Disorders Tretinoin 10.8316206674 16197459
MESH:D001836 Body Weight Changes Tetrachlorodibenzodioxin 2.9315340226
MESH:D001848 Bone Diseases, Developmental Tetrachlorodibenzodioxin 6.0015746008
MESH:D001848 Bone Diseases, Developmental Valproic Acid 6.008888407
MESH:D019046 Bone Marrow Neoplasms Doxorubicin 3.8414601052
MESH:D001919 Bradycardia Capsaicin 8.1118207255
MESH:D001919 Bradycardia Phenylephrine 8.1115306635
MESH:D001930 Brain Injuries Pregnanolone 5.3815665606 15380490
MESH:D002545 Brain Ischemia Capsaicin 12.3219211983
MESH:D002545 Brain Ischemia Curcumin 12.3216770732
MESH:D002545 Brain Ischemia resveratrol 12.3217600658
MESH:D001932 Brain Neoplasms Curcumin 6.4817596214
MESH:D001932 Brain Neoplasms Doxorubicin 6.4817150277
MESH:D001943 Breast Neoplasms Benzo(a)pyrene 11.4117474063 20146248
MESH:D001943 Breast Neoplasms Cacodylic Acid 11.4117474063
MESH:D001943 Breast Neoplasms Curcumin 11.4119250217 16243823 18462866 18593918
MESH:D001943 Breast Neoplasms Dietary Fats 11.4120435547
MESH:D001943 Breast Neoplasms Diethylnitrosamine 11.4117474063
MESH:D001943 Breast Neoplasms Diethylstilbestrol 11.4117129689 15324884
MESH:D001943 Breast Neoplasms Doxorubicin 11.4116096432 16115903 16264153 18234424 19526202 18382427 18628466 16826403 15939500 15136595 18695136 16322301 17369602 17426702 17983394 15567936 15668708 15994142 15634643 15692762 16935488 11325840 15993339 16595493
MESH:D001943 Breast Neoplasms Estradiol 11.4119861407 12948864 17289903 18497071 17018787 16675129 17261762 14630087
MESH:D001943 Breast Neoplasms Genistein 11.4116541309 16873071 17200150
MESH:D001943 Breast Neoplasms Heptachlor 11.418738476
MESH:D001943 Breast Neoplasms resveratrol 11.4117534123 16393696 17651959
MESH:D001943 Breast Neoplasms Tamoxifen 11.4119289846 20544844 20859285 11161223 15668708 19011961 19084267 19155303 20005174 17893378 17261762 20065188 21152245 18351453 18984771 20135344 18425577 19066611 17049068 19189210 19410462 16818667 16873071 19221464 21138602 19059307 20390343 18997820 17440819 16273361 19200415 19142967 19103187 17242785 19487384 19115204 19288272 18815881 18821012 15565566 19244106 16202921 19189212 18629630 18855134
MESH:D001943 Breast Neoplasms Tetrachlorodibenzodioxin 11.4120435547
MESH:D001943 Breast Neoplasms Tretinoin 11.4116166294 16443354 16873071
MESH:D001943 Breast Neoplasms Vanadium 11.4115565634
MESH:D029481 Bronchitis, Chronic fluticasone 5.8517687719
MESH:D001997 Bronchopulmonary Dysplasia Tretinoin 3.7416813970
MESH:D002056 Burns Ethanol 3.8216374292
MESH:D002181 Candidiasis, Vulvovaginal Estradiol 3.6116111702
MESH:D002276 Carcinoid Tumor Doxorubicin 3.9516051944
MESH:D002277 Carcinoma Curcumin 5.9618593918
MESH:D002277 Carcinoma Tetrachlorodibenzodioxin 5.9616835633
MESH:D018270 Carcinoma, Ductal, Breast Tamoxifen 3.6719066611
MESH:D018236 Carcinoma, Embryonal Tretinoin 4.2916168501
MESH:D006528 Carcinoma, Hepatocellular Diethylnitrosamine 23.2816502159 19519916 18210153 16830150 19052882 19171122 20727157 17162532 18691550 11831363 17761372 21159647 18788625 18494052 16681979 17428255 16569478 18506893 17055752 20101231 18393292 20007298 3084413 16288022 18971187 20935162 16328049 17173139 18665156 16779866 20514400 16540662 19418558 17138121 16878318 20524982 19919837 19822196 19208518 20512989 16935385 19539802 18056438 18978308 20214788 16807293 10672840 18785209 20432363 19394651 10737359 19335982 16698587 3581430 17978847 19383236 20084675 19107877 19701751
MESH:D006528 Carcinoma, Hepatocellular Diethylstilbestrol 23.2816924424 15948411
MESH:D006528 Carcinoma, Hepatocellular Doxorubicin 23.2816234567 18059187 16023760 17876044
MESH:D006528 Carcinoma, Hepatocellular Estradiol 23.2816924424
MESH:D006528 Carcinoma, Hepatocellular Ethanol 23.2818788625 15763234 15289165
MESH:D006528 Carcinoma, Hepatocellular Genistein 23.2816924424
MESH:D006528 Carcinoma, Hepatocellular Phenobarbital 23.2817173139 1701930 20935162 20007298 6705139
MESH:D006528 Carcinoma, Hepatocellular resveratrol 23.2819321006 16227395
MESH:D006528 Carcinoma, Hepatocellular sodium arsenite 23.2815276417 16507464 17306315
MESH:D006528 Carcinoma, Hepatocellular Tamoxifen 23.2816924424
MESH:D006528 Carcinoma, Hepatocellular Tretinoin 23.281917145
MESH:D006528 Carcinoma, Hepatocellular Vanadium 23.2816830150 16878318
MESH:D018827 Carcinoma, Lewis Lung resveratrol 3.7516675471
MESH:D002289 Carcinoma, Non-Small-Cell Lung Curcumin 2.6118414057
MESH:D002292 Carcinoma, Renal Cell Doxorubicin 2.6916201981 1485588
MESH:D002294 Carcinoma, Squamous Cell Benzo(a)pyrene 16.5620419170
MESH:D002294 Carcinoma, Squamous Cell Curcumin 16.5618462866
MESH:D002294 Carcinoma, Squamous Cell Doxorubicin 16.566189445
MESH:D002294 Carcinoma, Squamous Cell resveratrol 16.5616227395
MESH:D002294 Carcinoma, Squamous Cell sodium arsenite 16.5618572023
MESH:D002294 Carcinoma, Squamous Cell Tetradecanoylphorbol Acetate 16.5618922899
MESH:D002294 Carcinoma, Squamous Cell Tretinoin 16.5616051514 16096774
MESH:D002295 Carcinoma, Transitional Cell Tamoxifen 2.8617572228
MESH:D006332 Cardiomegaly Ethanol 8.3019332462
MESH:D006332 Cardiomegaly Phenylephrine 8.3015728586 17124262 17287366 11754973 11179087 16170337
MESH:D006332 Cardiomegaly Tetrachlorodibenzodioxin 8.3016120746 18670907 18850075
MESH:D009202 Cardiomyopathies Doxorubicin 2.9216242529 16651473 16612575 17519947 17974986 17131338 17007740 17351982 16455267 17308081 17924179 18627295 16109756 16364871 16952015 16731534 16278810 17329180 15505089 15476868 16269455 17928571 17382496 15811867 15792986
MESH:D002311 Cardiomyopathy, Dilated Doxorubicin 2.5716243910 17334414
MESH:D002318 Cardiovascular Diseases Aldosterone 16.0511230374
MESH:D002318 Cardiovascular Diseases daidzein 16.0516332659
MESH:D002318 Cardiovascular Diseases Genistein 16.0516332659
MESH:D002318 Cardiovascular Diseases Hydrogen Peroxide 16.0516936243
MESH:D002318 Cardiovascular Diseases resveratrol 16.0515458977
MESH:D020212 Carotid Artery Injuries tetracycline CMT-3 5.7114507662
MESH:D002386 Cataract 4-amino-2,6-dinitrotoluene 9.3314694615
MESH:D002386 Cataract Adenosine Triphosphate 9.3315003327
MESH:D002386 Cataract Tretinoin 9.3317460283
MESH:D002471 Cell Transformation, Neoplastic 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 18.2020889678
MESH:D002471 Cell Transformation, Neoplastic Diethylnitrosamine 18.2017174075 2727394 21159647 7505956
MESH:D002471 Cell Transformation, Neoplastic Estradiol 18.2018566989
MESH:D002471 Cell Transformation, Neoplastic monomethylarsonous acid 18.2019716837
MESH:D002471 Cell Transformation, Neoplastic sodium arsenite 18.2020056578 19524636
MESH:D002471 Cell Transformation, Neoplastic Vanadium 18.2017174075
MESH:D002493 Central Nervous System Diseases Phenobarbital 3.424080065
MESH:D018290 Cervical Intraepithelial Neoplasia Tretinoin 3.7416129372
MESH:D002659 Child Development Disorders, Pervasive Valproic Acid 2.3220734317
MESH:D018281 Cholangiocarcinoma Diethylnitrosamine 6.8819052882
MESH:D018281 Cholangiocarcinoma Tetrachlorodibenzodioxin 6.8816835633
MESH:D002779 Cholestasis Ethinyl Estradiol 5.5217681005 16105132 17110522 16919318 11677210 15861022 17333356
MESH:D002779 Cholestasis pirinixic acid 5.5219176532
MESH:D002822 Choriocarcinoma Tretinoin 4.2916461808
MESH:D002971 Cleft Lip Ethanol 3.0615513904
MESH:D002972 Cleft Palate Ethanol 10.4015513904
MESH:D002972 Cleft Palate Tetrachlorodibenzodioxin 10.4015340226 16354765 15668235 12621046 8697196
MESH:D002972 Cleft Palate Tretinoin 10.409407595
MESH:D002972 Cleft Palate Urethane 10.4012810352
MESH:D003092 Colitis Curcumin 11.3418200517 16804969 16782535
MESH:D003092 Colitis resveratrol 11.3416474422
MESH:D003092 Colitis Tretinoin 11.3417035595
MESH:D003103 Coloboma Curcumin 3.7718809619
MESH:D003110 Colonic Neoplasms Curcumin 13.2919359593 16340194
MESH:D003110 Colonic Neoplasms Deoxycholic Acid 13.2916213893
MESH:D003110 Colonic Neoplasms Dexamethasone 13.2915824018
MESH:D003110 Colonic Neoplasms Genistein 13.2917182828
MESH:D003110 Colonic Neoplasms irinotecan 13.2917287894 17725105
MESH:D003110 Colonic Neoplasms resveratrol 13.2916338953
MESH:D003110 Colonic Neoplasms Vanadium 13.2918155637
MESH:D015179 Colorectal Neoplasms Doxorubicin 2.8818802399 18259882
MESH:D015179 Colorectal Neoplasms irinotecan 2.8818259882 18509181 17159606 17454858 16391804 16303861 15273666
MESH:D015179 Colorectal Neoplasms resveratrol 2.8816550006
MESH:D000013 Congenital Abnormalities 4-amino-2,6-dinitrotoluene 6.7515095906
MESH:D000013 Congenital Abnormalities Tetrachlorodibenzodioxin 6.7517141729 14669216
MESH:D016510 Corneal Neovascularization Curcumin 4.0618497527
MESH:D003327 Coronary Disease resveratrol 3.1516507316
MESH:D003371 Cough Capsaicin 4.3210350223
MESH:D019465 Craniofacial Abnormalities Dexamethasone 9.2317728286
MESH:D019465 Craniofacial Abnormalities Ethanol 9.2315451040 19302082 10194807 15451039 15513904 11873399 11198716
MESH:D019465 Craniofacial Abnormalities Lead 9.2319769572
MESH:D019465 Craniofacial Abnormalities lead acetate 9.2319769572
MESH:D019465 Craniofacial Abnormalities Tetrachlorodibenzodioxin 9.2315322242 20055451 10048152
MESH:D019465 Craniofacial Abnormalities Tretinoin 9.239125849 14991402 17551590 9224671 10589399 16925845 8800419 9142499 9211117 9664655
MESH:D019465 Craniofacial Abnormalities Valproic Acid 9.2316575769 8888407 17688650
MESH:D003456 Cryptorchidism Diethylstilbestrol 3.7512952375 16002989
MESH:D003704 Dementia Lead 4.4816140633
MESH:D003711 Demyelinating Diseases Tamoxifen 3.5319031437
MESH:D017449 Dermatitis, Allergic Contact Dexamethasone 2.6512438553
MESH:D003876 Dermatitis, Atopic pirinixic acid 1.9518249437
MESH:D003920 Diabetes Mellitus rosiglitazone 3.5717446233
MESH:D003921 Diabetes Mellitus, Experimental resveratrol 3.0616873680
MESH:D003924 Diabetes Mellitus, Type 2 Curcumin 13.1218403477
MESH:D003924 Diabetes Mellitus, Type 2 daidzein 13.1216647724
MESH:D003924 Diabetes Mellitus, Type 2 Diethylnitrosamine 13.1220387270
MESH:D003924 Diabetes Mellitus, Type 2 Genistein 13.1216647724
MESH:D003924 Diabetes Mellitus, Type 2 rosiglitazone 13.1212642470
MESH:D003924 Diabetes Mellitus, Type 2 Tetrachlorodibenzodioxin 13.1217107852
MESH:D003928 Diabetic Nephropathies Curcumin 15.4418204486
MESH:D003928 Diabetic Nephropathies Estradiol 15.4419279558
MESH:D003928 Diabetic Nephropathies resveratrol 15.4416286809
MESH:D003928 Diabetic Nephropathies Tamoxifen 15.4419279558
MESH:D003929 Diabetic Neuropathies Pregnanolone 5.6117187935
MESH:D003967 Diarrhea Dexamethasone 2.927237001
MESH:D056486 Drug-Induced Liver Injury 4-amino-2,6-dinitrotoluene 13.1821346803
MESH:D056486 Drug-Induced Liver Injury bicyclol 13.1815998439
MESH:D056486 Drug-Induced Liver Injury Diethylnitrosamine 13.1819107877
MESH:D056486 Drug-Induced Liver Injury Doxorubicin 13.1817416283
MESH:D056486 Drug-Induced Liver Injury Ethanol 13.1811566570
MESH:D056486 Drug-Induced Liver Injury Tetrachlorodibenzodioxin 13.1820420201
MESH:D056486 Drug-Induced Liver Injury Valproic Acid 13.1819641884 1733752
MESH:D004362 Drug Toxicity Doxorubicin 5.8918602426
MESH:D004362 Drug Toxicity Tetrachlorodibenzodioxin 5.8911462148
MESH:D004381 Duodenal Ulcer Capsaicin 6.9611535926 10671773
MESH:D004381 Duodenal Ulcer Curcumin 6.9617351913
MESH:D050171 Dyslipidemias Dietary Fats 2.8018367378
MESH:D004421 Dystonia Phenobarbital 7.811851702
MESH:D004421 Dystonia Valproic Acid 7.811851702
MESH:D004485 Eczema Dexamethasone 3.6512438553
MESH:D004487 Edema Dexamethasone 21.0819703484
MESH:D004487 Edema pirinixic acid 21.0812083418
MESH:D004487 Edema resveratrol 21.088985016
MESH:D004487 Edema rosiglitazone 21.0812083418
MESH:D004487 Edema Staurosporine 21.088273558
MESH:D004487 Edema Tetrachlorodibenzodioxin 21.0812711302 11000095
MESH:D004487 Edema Tetradecanoylphorbol Acetate 21.0816716910 9599246 7812673 8273558 11698051 15177302 8113982
MESH:D004489 Edema, Cardiac Tetrachlorodibenzodioxin 9.0816714409 15322242 18230668
MESH:D004489 Edema, Cardiac Tretinoin 9.0818230668
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Ethinyl Estradiol 10.7112538720
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental resveratrol 10.7117872969
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Tamoxifen 10.7119031437
MESH:D004714 Endometrial Hyperplasia Diethylstilbestrol 9.0816402032
MESH:D004714 Endometrial Hyperplasia Genistein 9.0816402032
MESH:D016889 Endometrial Neoplasms daidzein 25.7211473722
MESH:D016889 Endometrial Neoplasms Diethylstilbestrol 25.7215700306 16804899
MESH:D016889 Endometrial Neoplasms Doxorubicin 25.7217359293
MESH:D016889 Endometrial Neoplasms Estradiol 25.7218566989 19148513 11473722
MESH:D016889 Endometrial Neoplasms Genistein 25.7211473722
MESH:D016889 Endometrial Neoplasms Tamoxifen 25.7216202921 20544844 17893378 19155303
MESH:D016889 Endometrial Neoplasms Tretinoin 25.7216569247
MESH:D004715 Endometriosis Mifepristone 6.6616134523
MESH:D004715 Endometriosis Tetrachlorodibenzodioxin 6.669294722 10568697
MESH:D004719 Endomyocardial Fibrosis Doxorubicin 4.2918037988
MESH:D019446 Endotoxemia Lipopolysaccharides 3.5515328337 15821434 17637181
MESH:D020345 Enterocolitis, Necrotizing resveratrol 4.0217923197
MESH:D004831 Epilepsies, Myoclonic Phenobarbital 8.053659116
MESH:D004831 Epilepsies, Myoclonic Valproic Acid 8.0517275665 3659116
MESH:D004828 Epilepsies, Partial Phenobarbital 7.133922381 11558140
MESH:D004828 Epilepsies, Partial Valproic Acid 7.133922381 16628512
MESH:D004827 Epilepsy Phenobarbital 4.9320417680
MESH:D004827 Epilepsy Valproic Acid 4.9318234410 20417680
MESH:D004832 Epilepsy, Absence Phenobarbital 6.436401628
MESH:D004832 Epilepsy, Absence Valproic Acid 6.437562514 6426943 6254150
MESH:D017029 Epilepsy, Complex Partial Phenobarbital 8.557750514
MESH:D017029 Epilepsy, Complex Partial Valproic Acid 8.557750514
MESH:D004830 Epilepsy, Tonic-Clonic Phenobarbital 7.683659116
MESH:D004830 Epilepsy, Tonic-Clonic Valproic Acid 7.683659116
MESH:D007172 Erectile Dysfunction daidzein 4.2114972507
MESH:D004892 Erythema Multiforme Thiram 5.7816750123
MESH:D004931 Esophageal Achalasia Diethylnitrosamine 4.2516302075
MESH:D004935 Esophageal Diseases Capsaicin 4.8519566590
MESH:D004938 Esophageal Neoplasms 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 5.4020426865
MESH:D004938 Esophageal Neoplasms Benzo(a)pyrene 5.4016530937
MESH:D004938 Esophageal Neoplasms Ethanol 5.4016704527
MESH:D004942 Esophagitis, Peptic Bile Acids and Salts 5.6911346197
MESH:D020329 Essential Tremor Lead 5.0814594619 18007985
MESH:D005124 Eye Abnormalities Tetrachlorodibenzodioxin 6.5911564622
MESH:D005124 Eye Abnormalities Tretinoin 6.5916938888 9664655
MESH:D005221 Fatigue Amphetamine 4.7519890266
MESH:D005234 Fatty Liver bicyclol 39.7116409862
MESH:D005234 Fatty Liver Curcumin 39.7119297423
MESH:D005234 Fatty Liver Dietary Fats 39.7117967931 19004024 18296743 19551842
MESH:D005234 Fatty Liver Diethylnitrosamine 39.7120387270 21071580
MESH:D005234 Fatty Liver Ethanol 39.7119236843 16409862 18620774
MESH:D005234 Fatty Liver Ethinyl Estradiol 39.7115345470
MESH:D005234 Fatty Liver pirinixic acid 39.7120131406 19236843
MESH:D005234 Fatty Liver rosiglitazone 39.7119196556
MESH:D005234 Fatty Liver Tamoxifen 39.7114986274 19224547
MESH:D005234 Fatty Liver Valproic Acid 39.7119224547 14986274
MESH:D005235 Fatty Liver, Alcoholic Ethanol 4.8017920746
MESH:D052776 Female Urogenital Diseases Diethylstilbestrol 6.2616611131 15751030 16534752 16513791 16002989
MESH:D052776 Female Urogenital Diseases Tamoxifen 6.2616709447
MESH:D005310 Fetal Alcohol Syndrome Ethanol 4.4510194807 15451040 15513904 16946407
MESH:D005313 Fetal Death Tetrachlorodibenzodioxin 2.6311858732
MESH:D005315 Fetal Diseases Valproic Acid 4.0216575769
MESH:D005317 Fetal Growth Retardation Lead 13.8919769572
MESH:D005317 Fetal Growth Retardation lead acetate 13.8919769572
MESH:D005317 Fetal Growth Retardation Valproic Acid 13.898888407 18558336
MESH:D005334 Fever Lipopolysaccharides 3.279205823 11852909
MESH:D018221 Fibromatosis, Abdominal Tamoxifen 3.6814745880
MESH:D018222 Fibromatosis, Aggressive Doxorubicin 8.6319069698
MESH:D018222 Fibromatosis, Aggressive Tamoxifen 8.6319069698
MESH:D005355 Fibrosis Curcumin 14.4618705752
MESH:D005355 Fibrosis Dietary Fats 14.4618296743
MESH:D005355 Fibrosis Tetrachlorodibenzodioxin 14.4620067830
MESH:D005355 Fibrosis Tretinoin 14.4617994277
MESH:D005756 Gastritis Ethanol 3.8315046732
MESH:D005770 Gastrointestinal Neoplasms Curcumin 3.8618462866
MESH:D005833 Genital Neoplasms, Female Diethylstilbestrol 10.0016452187
MESH:D005833 Genital Neoplasms, Female sodium arsenite 10.0016452187
MESH:D005909 Glioblastoma Capsaicin 15.8118405923
MESH:D005909 Glioblastoma Curcumin 15.8117596214
MESH:D005909 Glioblastoma Doxorubicin 15.8117150277
MESH:D005909 Glioblastoma Genistein 15.8116598420
MESH:D005909 Glioblastoma Tretinoin 15.8117312396
MESH:D006058 Gonadal Disorders Tetrachlorodibenzodioxin 3.7310696789
MESH:D006258 Head and Neck Neoplasms Curcumin 9.3818462866 18829502
MESH:D006258 Head and Neck Neoplasms Doxorubicin 9.3815692506
MESH:D006258 Head and Neck Neoplasms Tretinoin 9.3816096774
MESH:D006317 Hearing Loss, Noise-Induced Tretinoin 4.2916084493
MESH:D006356 Heartburn Capsaicin 4.8519566590
MESH:D006330 Heart Defects, Congenital 3,4,3',4'-tetrachlorobiphenyl 11.6811294989
MESH:D006330 Heart Defects, Congenital Benzo(a)pyrene 11.6820471113
MESH:D006330 Heart Defects, Congenital Tetrachlorodibenzodioxin 11.6811294989 10048152
MESH:D006330 Heart Defects, Congenital Tretinoin 11.689664655 14991402
MESH:D006331 Heart Diseases Doxorubicin 5.9816330681 18006777 18674790 17875725 16707910 12587719 16879835 17888722 16495754 16244371 16244372 16144979 14766674
MESH:D006331 Heart Diseases Urethane 5.9816046796
MESH:D006333 Heart Failure Doxorubicin 5.0917481944
MESH:D006333 Heart Failure pirinixic acid 5.0920558911
MESH:D006394 Hemangiosarcoma Doxorubicin 3.1415692506
MESH:D006463 Hemolytic-Uremic Syndrome Lipopolysaccharides 3.6316366002
MESH:D006470 Hemorrhage Tetrachlorodibenzodioxin 2.5611000095
MESH:D006529 Hepatomegaly Phenobarbital 9.6416109766
MESH:D006529 Hepatomegaly pirinixic acid 9.6418467677 19772884 16221962 19176532
MESH:D006529 Hepatomegaly Tetrachlorodibenzodioxin 9.6416120746 12621046 15340226
MESH:D015417 Hereditary Sensory and Motor Neuropathy Curcumin 4.2117701891
MESH:D006548 Hernia, Diaphragmatic Dexamethasone 2.697520565
MESH:D006558 Herpes Genitalis Estradiol 4.1715709030
MESH:D006561 Herpes Simplex resveratrol 3.3416876885
MESH:D006689 Hodgkin Disease Doxorubicin 5.0917606976 18501091 15147373
MESH:D006689 Hodgkin Disease sodium arsenite 5.0912676792
MESH:D019584 Hot Flashes Estradiol 2.9017088409
MESH:D006849 Hydrocephalus Valproic Acid 4.0217688650
MESH:D006869 Hydronephrosis Tetrachlorodibenzodioxin 3.188697196 18606429 16354765 16959395 15340226
MESH:D006930 Hyperalgesia Capsaicin 13.0717434803 17043245
MESH:D006930 Hyperalgesia Ethanol 13.0718783367
MESH:D006930 Hyperalgesia rosiglitazone 13.0712083418
MESH:D006930 Hyperalgesia Tretinoin 13.0716870215
MESH:D006937 Hypercholesterolemia Curcumin 10.9318704882
MESH:D006937 Hypercholesterolemia Dietary Fats 10.9321332399
MESH:D006937 Hypercholesterolemia resveratrol 10.9317188708
MESH:D017681 Hypereosinophilic Syndrome Tretinoin 3.7416778211
MESH:D006943 Hyperglycemia pirinixic acid 2.4320558911
MESH:D020138 Hyperhomocysteinemia Superoxides 4.5412615666
MESH:D006948 Hyperkinesis Amphetamine 4.5914960337 1977408
MESH:D006949 Hyperlipidemias Dietary Fats 6.6821332399
MESH:D006949 Hyperlipidemias resveratrol 6.6816873680
MESH:D006965 Hyperplasia Diethylstilbestrol 3.6114722030 12960047
MESH:D006967 Hypersensitivity Butylated Hydroxytoluene 3.7717604070
MESH:D006973 Hypertension daidzein 8.9817169123
MESH:D006973 Hypertension Dexamethasone 8.9817042910
MESH:D006973 Hypertension Phenylephrine 8.988949925 12717712
MESH:D006973 Hypertension Tetrachlorodibenzodioxin 8.9818850075 18670907
MESH:D006984 Hypertrophy Phenylephrine 3.7818502941 12791704
MESH:D017379 Hypertrophy, Left Ventricular resveratrol 3.5517488730
MESH:D007021 Hypospadias Diethylstilbestrol 8.4916002989
MESH:D007021 Hypospadias Ethinyl Estradiol 8.4916945680 16569931
MESH:D020244 Infarction, Middle Cerebral Artery resveratrol 3.8217600658
MESH:D007246 Infertility Diethylstilbestrol 8.5915036965
MESH:D007246 Infertility Thiram 8.596420938
MESH:D007247 Infertility, Female Ethinyl Estradiol 2.6712013081
MESH:D007248 Infertility, Male Atrazine 11.0512948887
MESH:D007248 Infertility, Male Ethinyl Estradiol 11.0517937319
MESH:D007248 Infertility, Male Lead 11.0516780224
MESH:D007248 Infertility, Male sodium arsenite 11.0515346721 12646999
MESH:D007249 Inflammation Capsaicin 29.7816956363
MESH:D007249 Inflammation Curcumin 29.7816956363 18403477 17151092
MESH:D007249 Inflammation Dexamethasone 29.788960868 11099482
MESH:D007249 Inflammation Dietary Fats 29.7820412841
MESH:D007249 Inflammation Diethylnitrosamine 29.7818785209
MESH:D007249 Inflammation Lipopolysaccharides 29.7812878042 9205823 17255318 17237260 17963957
MESH:D007249 Inflammation resveratrol 29.7816366677
MESH:D007249 Inflammation rosiglitazone 29.7812083418
MESH:D007249 Inflammation Tamoxifen 29.7819457130
MESH:D007249 Inflammation Tetrachlorodibenzodioxin 29.7812878042 12200463
MESH:D007249 Inflammation Tetradecanoylphorbol Acetate 29.788273558 11698051 15177302 7562506 7812673
MESH:D015212 Inflammatory Bowel Diseases Curcumin 2.7918200517 18596194
MESH:D007251 Influenza, Human resveratrol 3.6916624496
MESH:D007333 Insulin Resistance Dietary Fats 12.6318457598 11836018
MESH:D007333 Insulin Resistance Estradiol 12.6316393666 16627594
MESH:D007333 Insulin Resistance pirinixic acid 12.6316306350
MESH:D007333 Insulin Resistance rosiglitazone 12.6316306350
MESH:D007410 Intestinal Diseases Superoxides 7.5610210152
MESH:D007410 Intestinal Diseases Tretinoin 7.5617994277
MESH:D007414 Intestinal Neoplasms Curcumin 3.4710783313
MESH:D019189 Iron Metabolism Disorders Lipopolysaccharides 3.8417255318
MESH:D007569 Jaw Abnormalities Ethanol 12.7315513904
MESH:D007569 Jaw Abnormalities Tetrachlorodibenzodioxin 12.7316580747
MESH:D007569 Jaw Abnormalities Tretinoin 12.7317551590 15992940
MESH:D007674 Kidney Diseases Doxorubicin 6.9115369732 15699352 16775033
MESH:D007674 Kidney Diseases Estradiol 6.9115618244
MESH:D007674 Kidney Diseases sodium arsenite 6.9120008137
MESH:D007676 Kidney Failure, Chronic Doxorubicin 7.5616707910
MESH:D007676 Kidney Failure, Chronic Hydrogen Peroxide 7.5616518626
MESH:D007680 Kidney Neoplasms Diethylstilbestrol 8.3714681315 16762066 15003126
MESH:D007680 Kidney Neoplasms Estradiol 8.3715610895
MESH:D007680 Kidney Neoplasms Tamoxifen 8.3718625569
MESH:D007683 Kidney Tubular Necrosis, Acute Calcium 4.1816316344
MESH:D007855 Lead Poisoning Lead 5.0816700817
MESH:D007859 Learning Disorders Diethylstilbestrol 11.5417184923
MESH:D007859 Learning Disorders Ethanol 11.5415451040
MESH:D007859 Learning Disorders Lead 11.5416384672
MESH:D007889 Leiomyoma Curcumin 3.7818555241
MESH:D007938 Leukemia Curcumin 7.5818462866
MESH:D007938 Leukemia Genistein 7.5818980019 17468513
MESH:D007938 Leukemia Tretinoin 7.5817143497
MESH:D004915 Leukemia, Erythroblastic, Acute Doxorubicin 4.2916085563
MESH:D015459 Leukemia-Lymphoma, Adult T-Cell Curcumin 3.4416106398
MESH:D007948 Leukemia, Monocytic, Acute PD 98059 4.3816972261
MESH:D007951 Leukemia, Myeloid Tretinoin 2.9319285840 16482212 16932348
MESH:D015470 Leukemia, Myeloid, Acute Tretinoin 3.1019850784 16294345 17596541
MESH:D015470 Leukemia, Myeloid, Acute Valproic Acid 3.1017596541 16294345
MESH:D015473 Leukemia, Promyelocytic, Acute resveratrol 5.7216087638
MESH:D015473 Leukemia, Promyelocytic, Acute Tretinoin 5.7217294898 17506722 19642359 19075265 19035177 12679006 17649720 17361223 16788101 16891316 17107899 19029980 15748426 16935935 9834237 17301526 16823087 19225113 17368321 17217047 16331271 16140955 17339181 17712046 16766008
MESH:D015458 Leukemia, T-Cell Curcumin 3.9516106398
MESH:D007970 Leukopenia Lipopolysaccharides 3.8515821434
MESH:D017880 Limb Deformities, Congenital Ethanol 6.1417676605
MESH:D017880 Limb Deformities, Congenital Tretinoin 6.149224671
MESH:D008064 Lipidoses Tamoxifen 2.5117567588 15342952
MESH:D008103 Liver Cirrhosis Dietary Fats 11.2818296743
MESH:D008103 Liver Cirrhosis Diethylnitrosamine 11.2818665156 19638242 18522880 20032147 18407596
MESH:D008103 Liver Cirrhosis Ethanol 11.2815289165
MESH:D008103 Liver Cirrhosis Phenobarbital 11.2821047994
MESH:D008104 Liver Cirrhosis, Alcoholic Ethanol 4.2518295389
MESH:D008106 Liver Cirrhosis, Experimental bicyclol 23.5615730626 16603200
MESH:D008106 Liver Cirrhosis, Experimental Curcumin 23.5617355460 18705752 18006644
MESH:D008106 Liver Cirrhosis, Experimental Dexamethasone 23.5616718785
MESH:D008106 Liver Cirrhosis, Experimental Doxorubicin 23.5616439617 16595196
MESH:D008106 Liver Cirrhosis, Experimental Estradiol 23.5614716833 14659978
MESH:D008106 Liver Cirrhosis, Experimental Ethanol 23.5618166357
MESH:D008106 Liver Cirrhosis, Experimental fasudil 23.5617761835
MESH:D008106 Liver Cirrhosis, Experimental Genistein 23.5617823541
MESH:D008106 Liver Cirrhosis, Experimental Lipopolysaccharides 23.5612878042
MESH:D008106 Liver Cirrhosis, Experimental pirinixic acid 23.5615474484
MESH:D008106 Liver Cirrhosis, Experimental rosiglitazone 23.5617347453 15980055
MESH:D008106 Liver Cirrhosis, Experimental Tamoxifen 23.5618564211
MESH:D008106 Liver Cirrhosis, Experimental Tetrachlorodibenzodioxin 23.5612878042
MESH:D008106 Liver Cirrhosis, Experimental Tretinoin 23.5616248980 18397230
MESH:D008107 Liver Diseases Capsaicin 6.8016956363
MESH:D008107 Liver Diseases Curcumin 6.8016956363
MESH:D008107 Liver Diseases Diethylnitrosamine 6.8017034775
MESH:D008107 Liver Diseases Phenobarbital 6.8019363144
MESH:D008108 Liver Diseases, Alcoholic Ethanol 3.8217347304 17207112
MESH:D008113 Liver Neoplasms 2,4,5,2',4',5'-hexachlorobiphenyl 35.6316835634 18644402
MESH:D008113 Liver Neoplasms Benzo(a)pyrene 35.6321137059 20195826
MESH:D008113 Liver Neoplasms Butylated Hydroxytoluene 35.6318177683
MESH:D008113 Liver Neoplasms Diethylnitrosamine 35.6319294768 10737359 18754104 20492335 20501860 19833225 21071580 20405173 2422723 19996281 19812893 20583210 19551842 9163691 19642983 19638242 18644402 12112319 18648771 19256749 19254457 21278145 20101389 12771043 19090486 19690152 2862719 21167192 20452335 19499222 18978307 19427195 15175105 16942905 18977376 20434301 20118626 19426721 19850985 21047994 19255062 19073162 20137499 15885732
MESH:D008113 Liver Neoplasms Diethylstilbestrol 35.6315890375 16712894
MESH:D008113 Liver Neoplasms Heptachlor 35.639544696 2422723
MESH:D008113 Liver Neoplasms Phenobarbital 35.638742319 15975961 19073162 19482888 21047994 19812893
MESH:D008113 Liver Neoplasms pirinixic acid 35.6320007298 15890375 16377806
MESH:D008113 Liver Neoplasms resveratrol 35.6319812893 19321006 19073162 20405173
MESH:D008113 Liver Neoplasms sodium arsenite 35.6316712894 15276417
MESH:D008113 Liver Neoplasms Tamoxifen 35.6316684651
MESH:D008113 Liver Neoplasms Tetrachlorodibenzodioxin 35.6316984957
MESH:D008113 Liver Neoplasms Urethane 35.6317093202 16391232 17559639
MESH:D008114 Liver Neoplasms, Experimental Deoxycholic Acid 15.746150874
MESH:D008114 Liver Neoplasms, Experimental Diethylnitrosamine 15.7418544905 18093689 17174075 18282651 18775883 19519916 2563599 18308698 19009564 17854601 19004024 16842330 9362446 18253720 16267830 18164116 19539802 21159647 18079962 3124819 17942915 19126423
MESH:D008114 Liver Neoplasms, Experimental Doxorubicin 15.7416842330 17085340
MESH:D008114 Liver Neoplasms, Experimental Phenobarbital 15.742563599 17172636 6150874 1399818 18308698
MESH:D008114 Liver Neoplasms, Experimental Tetrachlorodibenzodioxin 15.7412151625
MESH:D008114 Liver Neoplasms, Experimental Vanadium 15.7417174075
MESH:D008171 Lung Diseases sodium arsenite 2.5619095001
MESH:D017563 Lung Diseases, Interstitial Valproic Acid 3.4017228818
MESH:D055370 Lung Injury Asbestos, Crocidolite 6.5817365036
MESH:D055370 Lung Injury Lipopolysaccharides 6.5821114838
MESH:D008175 Lung Neoplasms Benzo(a)pyrene 16.0418569708 18816296 20464547 20869020 18520028 20064080 17053015 6695378 20135361
MESH:D008175 Lung Neoplasms Butylated Hydroxytoluene 16.0419359593 11246140 18597497 16337739 11696405 15390079 19925653
MESH:D008175 Lung Neoplasms Curcumin 16.0418462866 16243823 19359593
MESH:D008175 Lung Neoplasms Dexamethasone 16.0415824018 11195469
MESH:D008175 Lung Neoplasms Diethylnitrosamine 16.046695378 20970405 20512841 21163286
MESH:D008175 Lung Neoplasms Doxorubicin 16.0417418594 6189445
MESH:D008175 Lung Neoplasms sodium arsenite 16.0417077188 17306315 19931552 16712894 15276417
MESH:D008175 Lung Neoplasms Tamoxifen 16.0418625569
MESH:D008175 Lung Neoplasms Tetrachlorodibenzodioxin 16.0419555203 11884234
MESH:D008175 Lung Neoplasms Tetradecanoylphorbol Acetate 16.0411807781
MESH:D008175 Lung Neoplasms Urethane 16.0412957351 11323394 17255336 16337739 11992545 15136453 11807781 10997738 11544531 10530776 12466968 16788158 16289808 11307925 15166089 16007126 12765245 17093202 16204055 16391232 11497255 17195641 10822126 11246140 11893704 11552296 6695378 10779650 15902970 16926031 12117781 7750092 14587096 11062179 11074608
MESH:D008181 Lupus Nephritis Diethylstilbestrol 4.3015166399
MESH:D008223 Lymphoma Curcumin 8.8918462866
MESH:D008223 Lymphoma Diethylstilbestrol 8.8915700306
MESH:D008223 Lymphoma Doxorubicin 8.8916098063
MESH:D016393 Lymphoma, B-Cell resveratrol 3.5117088997
MESH:D008228 Lymphoma, Non-Hodgkin Doxorubicin 6.5017654614
MESH:D008228 Lymphoma, Non-Hodgkin resveratrol 6.5014749477
MESH:D016399 Lymphoma, T-Cell Curcumin 8.8116173963
MESH:D016399 Lymphoma, T-Cell Doxorubicin 8.8115621674
MESH:D052801 Male Urogenital Diseases Diethylstilbestrol 4.6516002989
MESH:D015674 Mammary Neoplasms, Animal resveratrol 7.2115688416
MESH:D015674 Mammary Neoplasms, Animal Tamoxifen 7.2119428831
MESH:D008325 Mammary Neoplasms, Experimental Butylated Hydroxytoluene 26.781500032
MESH:D008325 Mammary Neoplasms, Experimental Corticosterone 26.7812807724
MESH:D008325 Mammary Neoplasms, Experimental Doxorubicin 26.7815458769
MESH:D008325 Mammary Neoplasms, Experimental Estradiol 26.7817203775 16891317 11408345 11807958
MESH:D008325 Mammary Neoplasms, Experimental Genistein 26.7814578162 12929590
MESH:D008325 Mammary Neoplasms, Experimental resveratrol 26.7811606380 8985016
MESH:D008325 Mammary Neoplasms, Experimental rosiglitazone 26.7816827153
MESH:D008325 Mammary Neoplasms, Experimental Tamoxifen 26.7814580682 19196723 11731420 16827153 19196722
MESH:D008325 Mammary Neoplasms, Experimental Tetradecanoylphorbol Acetate 26.788985016
MESH:D020149 Manganese Poisoning Estradiol 9.7819453300
MESH:D020149 Manganese Poisoning Tamoxifen 9.7819453300
MESH:D008527 Medulloblastoma Tretinoin 2.3617453147
MESH:D008545 Melanoma 4-((3-bromophenyl)amino)-6,7-dimethoxyquinazoline 11.6116077934
MESH:D008545 Melanoma Curcumin 11.6117885582 18462866
MESH:D008545 Melanoma Doxorubicin 11.6116827129
MESH:D008545 Melanoma resveratrol 11.6117992120
MESH:D008545 Melanoma sodium arsenite 11.6119082730 16487513
MESH:D008545 Melanoma Tamoxifen 11.6112393984 19393235
MESH:D008545 Melanoma Tretinoin 11.6116752155
MESH:D018328 Melanoma, Amelanotic Tamoxifen 3.3415990972
MESH:D008569 Memory Disorders Curcumin 11.5217263510
MESH:D008569 Memory Disorders Ethanol 11.5218411066 15451040
MESH:D008569 Memory Disorders Lead 11.5217263510 16384672
MESH:D008591 Meningomyelocele Tretinoin 3.5916940565
MESH:D008654 Mesothelioma Asbestos, Crocidolite 7.8118303189 16966607 16166281
MESH:D008654 Mesothelioma Atrazine 7.811916698
MESH:D008654 Mesothelioma Doxorubicin 7.8117638057
MESH:D008659 Metabolic Diseases resveratrol 3.6017112576
MESH:D024821 Metabolic Syndrome X rosiglitazone 3.6617261469
MESH:D008881 Migraine Disorders Valproic Acid 2.5518803445 18765137
MESH:D028361 Mitochondrial Diseases Doxorubicin 3.7215792986
MESH:D009062 Mouth Neoplasms Benzo(a)pyrene 2.5116381670
MESH:D052016 Mucositis Doxorubicin 9.6117415656
MESH:D052016 Mucositis irinotecan 9.6117159606
MESH:D009101 Multiple Myeloma Capsaicin 12.0417505005
MESH:D009101 Multiple Myeloma Curcumin 12.0419372569
MESH:D009101 Multiple Myeloma Dexamethasone 12.0415867202 15744524 16118317
MESH:D009101 Multiple Myeloma resveratrol 12.0416490592 17049120 16267019 17164350 14749477 17935668
MESH:D009134 Muscular Atrophy, Spinal Curcumin 9.6017962980
MESH:D009134 Muscular Atrophy, Spinal resveratrol 9.6017962980
MESH:D009135 Muscular Diseases pirinixic acid 2.6816239165
MESH:D009139 Musculoskeletal Abnormalities Valproic Acid 3.258888407
MESH:D009190 Myelodysplastic Syndromes Dexamethasone 9.109809623
MESH:D009190 Myelodysplastic Syndromes Tretinoin 9.1017596541
MESH:D009190 Myelodysplastic Syndromes Valproic Acid 9.1017596541
MESH:D009203 Myocardial Infarction Doxorubicin 9.8515857846 19429709
MESH:D009203 Myocardial Infarction Genistein 9.8517141266
MESH:D009203 Myocardial Infarction pirinixic acid 9.8519151258
MESH:D009203 Myocardial Infarction resveratrol 9.8516317513 17188708 16456233 16525036 17015251 17125593
MESH:D017202 Myocardial Ischemia resveratrol 6.6717125593 17015251
MESH:D017202 Myocardial Ischemia Tetrachlorodibenzodioxin 6.6712213967
MESH:D015428 Myocardial Reperfusion Injury Estradiol 10.2116810080
MESH:D015428 Myocardial Reperfusion Injury Genistein 10.2117141266
MESH:D015428 Myocardial Reperfusion Injury pirinixic acid 10.2116411023
MESH:D009205 Myocarditis resveratrol 3.9117322642
MESH:D020191 Myoclonic Epilepsies, Progressive Phenobarbital 3.6317484760
MESH:D009361 Neoplasm Invasiveness Curcumin 8.3418495463
MESH:D009361 Neoplasm Invasiveness tetracycline CMT-3 8.3411172680 11172682
MESH:D009362 Neoplasm Metastasis Diethylnitrosamine 9.999029167 3581430
MESH:D009362 Neoplasm Metastasis Doxorubicin 9.9918259882
MESH:D009362 Neoplasm Metastasis irinotecan 9.9918259882
MESH:D009362 Neoplasm Metastasis Tamoxifen 9.9919393235
MESH:D009364 Neoplasm Recurrence, Local Tamoxifen 2.1619410462
MESH:D009369 Neoplasms 2,4,5,2',4',5'-hexachlorobiphenyl 16.298820588
MESH:D009369 Neoplasms Benzo(a)pyrene 16.2911141357
MESH:D009369 Neoplasms Diethylstilbestrol 16.2915313581
MESH:D009369 Neoplasms pirinixic acid 16.2917405874
MESH:D009369 Neoplasms sodium arsenite 16.2911559025
MESH:D009369 Neoplasms Tretinoin 16.2916594593 16946489
MESH:D009369 Neoplasms Urethane 16.2915625555
MESH:D009374 Neoplasms, Experimental resveratrol 10.698985016
MESH:D009374 Neoplasms, Experimental sodium arsenite 10.6920056578
MESH:D009374 Neoplasms, Experimental Urethane 10.6915582191
MESH:D009376 Neoplasms, Hormone-Dependent Curcumin 7.9912497104
MESH:D009376 Neoplasms, Hormone-Dependent Tamoxifen 7.9919189210 19196722 19200415
MESH:D009389 Neovascularization, Pathologic Estradiol 2.8917289903
MESH:D009401 Nephrosis Doxorubicin 3.9416899518 16636307
MESH:D009404 Nephrotic Syndrome Doxorubicin 3.2715640375 16889571
MESH:D009421 Nervous System Malformations Diethylstilbestrol 22.2611399458
MESH:D009421 Nervous System Malformations Estradiol 22.2616427766 11399458
MESH:D009421 Nervous System Malformations Genistein 22.2616427766
MESH:D009421 Nervous System Malformations Tetrachlorodibenzodioxin 22.2614600291
MESH:D009421 Nervous System Malformations Tretinoin 22.269125849
MESH:D009423 Nervous System Neoplasms Curcumin 4.7618462866
MESH:D009436 Neural Tube Defects sodium arsenite 8.6012854658
MESH:D009436 Neural Tube Defects Tretinoin 8.609142499
MESH:D009436 Neural Tube Defects Valproic Acid 8.6016359493 8888407
MESH:D009447 Neuroblastoma Doxorubicin 5.4215555623
MESH:D009447 Neuroblastoma irinotecan 5.428761367
MESH:D019636 Neurodegenerative Diseases Amphetamine 10.1615183010
MESH:D019636 Neurodegenerative Diseases Diethylnitrosamine 10.1620387270
MESH:D019636 Neurodegenerative Diseases resveratrol 10.1617652729
MESH:D017599 Neuroectodermal Tumors irinotecan 3.888761367
MESH:D020078 Neurogenic Inflammation Capsaicin 8.3417961222
MESH:D020078 Neurogenic Inflammation resveratrol 8.3417929310
MESH:D009461 Neurologic Manifestations Diethylnitrosamine 4.2520387270
MESH:D009765 Obesity Capsaicin 8.0819056576
MESH:D009765 Obesity Curcumin 8.0819297423
MESH:D009765 Obesity Dietary Fats 8.0821332399 20132043 18457598 18674790 16723640 19632207 17217161 11836018 20518802
MESH:D009765 Obesity pirinixic acid 8.0820558911
MESH:D009784 Occupational Diseases 4-amino-2,6-dinitrotoluene 3.3514694615
MESH:D010009 Osteochondrodysplasias Thiram 4.8517954590 15518828 15899490
MESH:D010018 Osteomalacia Phenobarbital 3.5217016548
MESH:D010024 Osteoporosis Calcium 8.5917882678
MESH:D010024 Osteoporosis Curcumin 8.5918719352
MESH:D010024 Osteoporosis Genistein 8.5919401787
MESH:D015663 Osteoporosis, Postmenopausal Genistein 7.5316169203
MESH:D015663 Osteoporosis, Postmenopausal resveratrol 7.5317513867
MESH:D012516 Osteosarcoma Doxorubicin 3.4115930896
MESH:D010051 Ovarian Neoplasms 4-((3-bromophenyl)amino)-6,7-dimethoxyquinazoline 20.5616211241
MESH:D010051 Ovarian Neoplasms Curcumin 20.5619020741 18462866
MESH:D010051 Ovarian Neoplasms Estradiol 20.5619401270
MESH:D010051 Ovarian Neoplasms Genistein 20.5619005980
MESH:D010051 Ovarian Neoplasms Mifepristone 20.5616525653
MESH:D010051 Ovarian Neoplasms sodium arsenite 20.5617306315 15276417
MESH:D010051 Ovarian Neoplasms Tretinoin 20.5616936753
MESH:D010051 Ovarian Neoplasms Urethane 20.5616391232
MESH:D010146 Pain 1-(6-((3-methoxyestra-1,3,5(10)-trien-17-yl)amino)hexyl)-1H-pyrrole-2,5-dione 7.6218987195
MESH:D010146 Pain Capsaicin 7.6216996476 17043245 18987195 19081190 17434803 17084039
MESH:D010146 Pain Tretinoin 7.6216870215
MESH:D010190 Pancreatic Neoplasms Curcumin 15.2019196508 19401701 17440100
MESH:D010190 Pancreatic Neoplasms Diethylnitrosamine 15.2016540662
MESH:D010190 Pancreatic Neoplasms Ethanol 15.2012384795
MESH:D010190 Pancreatic Neoplasms Phenobarbital 15.2016965848
MESH:D010190 Pancreatic Neoplasms Tetradecanoylphorbol Acetate 15.2015976015
MESH:D010190 Pancreatic Neoplasms Tretinoin 15.2015976015
MESH:D016584 Panic Disorder Ethinyl Estradiol 2.8911578682
MESH:D010212 Papilloma Hydrogen Peroxide 6.8912065085
MESH:D010212 Papilloma Tetradecanoylphorbol Acetate 6.8912065085 18404319 8330346 18922899
MESH:D010300 Parkinson Disease Atrazine 2.9017218051
MESH:D010382 Peliosis Hepatis Tetrachlorodibenzodioxin 3.3812520081
MESH:D003557 Phyllodes Tumor Doxorubicin 4.2917983394
MESH:D010900 Pituitary Diseases Diethylstilbestrol 4.3014722030
MESH:D010911 Pituitary Neoplasms Diethylstilbestrol 9.3815687265 16977796
MESH:D010911 Pituitary Neoplasms Urethane 9.3816391232
MESH:D010995 Pleural Diseases Asbestos, Crocidolite 4.0610923243
MESH:D010997 Pleural Neoplasms Doxorubicin 4.2917638057
MESH:D011014 Pneumonia Butylated Hydroxytoluene 8.5811893704
MESH:D011014 Pneumonia Lipopolysaccharides 8.5812224865 11605937
MESH:D017119 Porphyria Cutanea Tarda Tetrachlorodibenzodioxin 2.7518163543
MESH:D011230 Precancerous Conditions Diethylnitrosamine 6.652563599
MESH:D011230 Precancerous Conditions Phenobarbital 6.652563599
MESH:D054198 Precursor Cell Lymphoblastic Leukemia-Lymphoma Dexamethasone 3.0021297632
MESH:D011297 Prenatal Exposure Delayed Effects Diethylstilbestrol 21.6317184923
MESH:D011297 Prenatal Exposure Delayed Effects Lead 21.6316384672
MESH:D011297 Prenatal Exposure Delayed Effects resveratrol 21.6316679765
MESH:D011297 Prenatal Exposure Delayed Effects Tetrachlorodibenzodioxin 21.6311222880 11399792 11118676 11896295
MESH:D011297 Prenatal Exposure Delayed Effects Valproic Acid 21.6320603192
MESH:D019048 Prostatic Intraepithelial Neoplasia Estradiol 3.1120887781
MESH:D011471 Prostatic Neoplasms Benzo(a)pyrene 4.7117292933
MESH:D011471 Prostatic Neoplasms Curcumin 4.7115129424 10851300 12497104 18226269 18769126 18156803 11398177
MESH:D011471 Prostatic Neoplasms Diethylstilbestrol 4.7115846301 17136230 15046698
MESH:D011471 Prostatic Neoplasms Doxorubicin 4.7115749863 18437689 16888761 15897917 16729912 16868541
MESH:D011471 Prostatic Neoplasms Estradiol 4.7116740699
MESH:D011471 Prostatic Neoplasms Genistein 4.7115378649 15256057 16925846
MESH:D011471 Prostatic Neoplasms Heptachlor 4.7112661182
MESH:D011471 Prostatic Neoplasms methylselenic acid 4.7116205645
MESH:D011471 Prostatic Neoplasms resveratrol 4.7117804756 17718901 17675339 16731767 17636462 15767336
MESH:D011471 Prostatic Neoplasms sodium arsenite 4.7116039940
MESH:D011471 Prostatic Neoplasms Tamoxifen 4.7115067354
MESH:D011471 Prostatic Neoplasms tetracycline CMT-3 4.7111857423 11172682
MESH:D011471 Prostatic Neoplasms Thiram 4.7119789329
MESH:D011507 Proteinuria Tretinoin 2.8216636307
MESH:D011537 Pruritus Ethinyl Estradiol 2.4815861022 16919318
MESH:D019310 Pseudolymphoma Phenobarbital 9.3312752131
MESH:D019310 Pseudolymphoma Valproic Acid 9.3312752131 11422049
MESH:D011625 Pterygium Tretinoin 3.9416723453
MESH:D011656 Pulmonary Emphysema Curcumin 3.7719168576
MESH:D011658 Pulmonary Fibrosis Asbestos, Crocidolite 2.6315814490 17365031 17975199 17322281
MESH:D051437 Renal Insufficiency Doxorubicin 3.4017922066
MESH:D051436 Renal Insufficiency, Chronic resveratrol 4.7216325855
MESH:D015427 Reperfusion Injury Capsaicin 11.5818460982 19211983
MESH:D015427 Reperfusion Injury pirinixic acid 11.5819058328
MESH:D015427 Reperfusion Injury resveratrol 11.5815827377 16314181 16317513 17058453 17520802
MESH:D015427 Reperfusion Injury Superoxides 11.5818460982
MESH:D012128 Respiratory Distress Syndrome, Adult Curcumin 6.7010666014 18379247
MESH:D012128 Respiratory Distress Syndrome, Adult Dexamethasone 6.7011700416 18379247
MESH:D012130 Respiratory Hypersensitivity Lipopolysaccharides 3.1210835634
MESH:D012135 Respiratory Sounds Atrazine 3.7011874814
MESH:D015619 Respiratory System Abnormalities Tetrachlorodibenzodioxin 3.0218990726
MESH:D012208 Rhabdomyosarcoma Tretinoin 8.2316283617 16116481
MESH:D012208 Rhabdomyosarcoma Valproic Acid 8.2319155313
MESH:D012509 Sarcoma Curcumin 7.0718462866
MESH:D012509 Sarcoma Doxorubicin 7.0716767912 17203757 17710206 15675481 15625365 18313854
MESH:D012512 Sarcoma, Ewing's Doxorubicin 3.4414601052 16326096
MESH:D012514 Sarcoma, Kaposi Doxorubicin 3.9417846226
MESH:D012559 Schizophrenia Valproic Acid 1.9319110320 15737665
MESH:D012640 Seizures Ethanol 6.339754883
MESH:D012640 Seizures Phenobarbital 6.333137016 11442880 16876388 4039156
MESH:D012640 Seizures Valproic Acid 6.3311044598 16876388 3137016 1511512 11738929 14763951 17978042 15475178
MESH:D003294 Seizures, Febrile Phenobarbital 3.976407741
MESH:D018805 Sepsis Curcumin 7.6318389075
MESH:D018805 Sepsis tetracycline CMT-3 7.6315489642 16003065
MESH:D012852 Sinusitis Phenylephrine 3.867327846
MESH:D012871 Skin Diseases monomethylarsonic acid 4.7921378128
MESH:D012871 Skin Diseases monomethylarsonous acid 4.7917431481
MESH:D012878 Skin Neoplasms Benzo(a)pyrene 31.3319755658 10029692
MESH:D012878 Skin Neoplasms Doxorubicin 31.3315692506
MESH:D012878 Skin Neoplasms Hydrogen Peroxide 31.3312065085
MESH:D012878 Skin Neoplasms resveratrol 31.338985016 15837718
MESH:D012878 Skin Neoplasms sodium arsenite 31.3319524636 18572023
MESH:D012878 Skin Neoplasms tert-Butylhydroperoxide 31.338532709
MESH:D012878 Skin Neoplasms Tetrachlorodibenzodioxin 31.3316192470
MESH:D012878 Skin Neoplasms Tetradecanoylphorbol Acetate 31.3312065085 8985016 8330346 11807781 18404319
MESH:D012878 Skin Neoplasms Tretinoin 31.3316467112
MESH:D012878 Skin Neoplasms Urethane 31.3311807781
MESH:D012983 Soft Tissue Neoplasms Doxorubicin 3.7415625365 17203757 16767912
MESH:D013088 Spermatocele Diethylstilbestrol 15.1716709447 16002989
MESH:D013088 Spermatocele Ethinyl Estradiol 15.1716709447
MESH:D013088 Spermatocele Tamoxifen 15.1716709447
MESH:D013119 Spinal Cord Injuries Tamoxifen 3.1919457130
MESH:D016135 Spinal Dysraphism sodium arsenite 7.2512854658
MESH:D016135 Spinal Dysraphism Valproic Acid 7.2519490988
MESH:D013226 Status Epilepticus Valproic Acid 3.6812833885
MESH:D019956 Stereotypic Movement Disorder Amphetamine 5.561977408
MESH:D013272 Stomach Diseases Dexamethasone 3.4815472012
MESH:D013274 Stomach Neoplasms Benzo(a)pyrene 4.842093021 20155912
MESH:D013274 Stomach Neoplasms Diethylnitrosamine 4.8418456281
MESH:D013274 Stomach Neoplasms Ethanol 4.8418456281
MESH:D013274 Stomach Neoplasms irinotecan 4.8415723263
MESH:D013274 Stomach Neoplasms Tretinoin 4.8417261132
MESH:D013276 Stomach Ulcer Curcumin 7.8219188055 16631530
MESH:D013276 Stomach Ulcer Dexamethasone 7.8215138204
MESH:D013276 Stomach Ulcer Ethanol 7.829562338 11906479 17189318 17918041 9211565 16755016
OMIM:601367 STROKE, ISCHEMIC resveratrol 3.7216321402
MESH:D013375 Substance Withdrawal Syndrome Ethanol 3.509754883
MESH:D013705 Temporomandibular Joint Disorders Capsaicin 4.8617997062
MESH:D013921 Thrombocytopenia Lipopolysaccharides 3.4115821434
MESH:D019851 Thrombophilia Ethinyl Estradiol 2.8311994571
MESH:D013927 Thrombosis Ethinyl Estradiol 2.4215669648
MESH:D013959 Thyroid Diseases Tetrachlorodibenzodioxin 3.0412697716
MESH:D013964 Thyroid Neoplasms Diethylnitrosamine 11.577505956
MESH:D013964 Thyroid Neoplasms Doxorubicin 11.5717909728 16010429
MESH:D013964 Thyroid Neoplasms Phenobarbital 11.571399818
MESH:D013964 Thyroid Neoplasms Tretinoin 11.5716026305 17045167
MESH:D013978 Tibial Fractures Estradiol 3.8219048282
MESH:D014062 Tongue Neoplasms resveratrol 7.4116227395
MESH:D014062 Tongue Neoplasms Tretinoin 7.4116051514
MESH:D014178 Translocation, Genetic Valproic Acid 4.3717262798
MESH:D014202 Tremor Lead 4.6321145352
MESH:D014376 Tuberculosis Tretinoin 2.6416040207
MESH:D020194 Unverricht-Lundborg Syndrome Valproic Acid 3.673119515
MESH:D001749 Urinary Bladder Neoplasms Benzo(a)pyrene 20.8917053015
MESH:D001749 Urinary Bladder Neoplasms Cacodylic Acid 20.8915537745
MESH:D001749 Urinary Bladder Neoplasms Curcumin 20.8918593936
MESH:D001749 Urinary Bladder Neoplasms Diethylstilbestrol 20.8916712894 17306315 16452187
MESH:D001749 Urinary Bladder Neoplasms Doxorubicin 20.8917653716
MESH:D001749 Urinary Bladder Neoplasms monomethylarsonous acid 20.8920375083
MESH:D001749 Urinary Bladder Neoplasms sodium arsenite 20.8917306315 16452187 16712894 11723127
MESH:D001749 Urinary Bladder Neoplasms Tamoxifen 20.8916712894 17572228 8653321
MESH:D014564 Urogenital Abnormalities Valproic Acid 3.818888407
MESH:D014565 Urogenital Neoplasms Curcumin 4.4118462866
MESH:D002583 Uterine Cervical Neoplasms Diethylstilbestrol 16.5016175088
MESH:D002583 Uterine Cervical Neoplasms resveratrol 16.5017473185
MESH:D002583 Uterine Cervical Neoplasms sodium arsenite 16.5011813266
MESH:D002583 Uterine Cervical Neoplasms Tretinoin 16.5016129372
MESH:D014591 Uterine Diseases Diethylstilbestrol 4.3014652134
MESH:D014594 Uterine Neoplasms Diethylstilbestrol 11.4215809267 16690809
MESH:D014594 Uterine Neoplasms Ethinyl Estradiol 11.4214692618
MESH:D014594 Uterine Neoplasms resveratrol 11.4217044934
MESH:D014604 Uveal Neoplasms Tretinoin 3.7516752155
MESH:D014605 Uveitis Dexamethasone 3.961336536
MESH:D014625 Vaginal Neoplasms Diethylstilbestrol 3.6116002989 16513791
MESH:D014652 Vascular Diseases sodium arsenite 3.5817056641
MESH:D054079 Vascular Malformations Tetrachlorodibenzodioxin 3.7312125929
MESH:D019043 Vascular Neoplasms Urethane 5.0510620525
MESH:D020301 Vasospasm, Intracranial fasudil 5.8819057314
MESH:D020246 Venous Thrombosis Ethinyl Estradiol 2.7715869587 14671159
MESH:D018487 Ventricular Dysfunction, Left Doxorubicin 7.6017334414 17678736 16364871 17638931
MESH:D018487 Ventricular Dysfunction, Left resveratrol 7.6017488730
MESH:D014820 Vitiligo Tretinoin 3.2516761959
MESH:D019282 Wasting Syndrome Tetrachlorodibenzodioxin 3.3815886252
MESH:D015430 Weight Gain Dietary Fats 3.0016723640
MESH:D009396 Wilms Tumor Tretinoin 3.2316287080
Pathway ID Pathway Name
KEGG:05143 African trypanosomiasis
KEGG:04960 Aldosterone-regulated sodium reabsorption
KEGG:05146 Amoebiasis
KEGG:04020 Calcium signaling pathway
REACT:15380 Diabetes pathways
KEGG:04961 Endocrine and other factor-regulated calcium reabsorption
KEGG:04012 ErbB signaling pathway
KEGG:04664 Fc epsilon RI signaling pathway
KEGG:04666 Fc gamma R-mediated phagocytosis
KEGG:04510 Focal adhesion
KEGG:04540 Gap junction
KEGG:04971 Gastric acid secretion
KEGG:05214 Glioma
KEGG:04724 Glutamatergic synapse
KEGG:04912 GnRH signaling pathway
REACT:604 Hemostasis
REACT:1505 Integration of energy metabolism
KEGG:04670 Leukocyte transendothelial migration
KEGG:04730 Long-term depression
KEGG:04720 Long-term potentiation
KEGG:04010 MAPK signaling pathway
KEGG:04916 Melanogenesis
REACT:21257 Metabolism of RNA
KEGG:04650 Natural killer cell mediated cytotoxicity
KEGG:05223 Non-small cell lung cancer
REACT:15295 Opioid Signalling
KEGG:04972 Pancreatic secretion
KEGG:05130 Pathogenic Escherichia coli infection
KEGG:05200 Pathways in cancer
KEGG:04070 Phosphatidylinositol signaling system
KEGG:04970 Salivary secretion
REACT:14797 Signaling by GPCR
REACT:11061 Signalling by NGF
REACT:13685 Synaptic Transmission
KEGG:04530 Tight junction
KEGG:04270 Vascular smooth muscle contraction
KEGG:04370 VEGF signaling pathway
KEGG:05110 Vibrio cholerae infection
KEGG:04310 Wnt signaling pathway
Pharmacogenomics Knowledge Base Top
  • PharmGKB Accession:PA33759
    • No data
    Releated disease ID Related disease Name
    PA445131Obesity
    PA443450Asthma
    PA444987Multiple Sclerosis
    PA443560Breast Neoplasms
    Releated drug ID Related drug Name
    PA448497aspirin
    PA451581tamoxifen
    PA450631nifedipine
    PA451365sirolimus
    PA449167cyclosporine
    PA451578tacrolimus
    PA448948chloroquine
    PA164743471adenosine triphosphate
    PA449748gemcitabine
    PA448068salbutamol
    PA134687887selective beta-2-adrenoreceptor agonists
    PA164713253Selective beta-2-adrenoreceptor agonists
    PA451620teriparatide
    PA448478l-arginine
    PA164747225l-citrulline
    PA450635nitric oxide
    Drug Bank Top
    Drugbank ID Action Drug Name Description
    DB00144 - Phosphatidylserine Dietary supplement;Micronutrient
    DB00163 - Vitamin E Dietary supplement;Micronutrient;Antioxidants;Vitamins/minerals;Vitamins
    No data
    No data
    No data

    Simple Query:


      (e.g. CHD8)

    Syndromic Genes

    Non-syndromic Genes

    AutismKB Statistics

    • Studies: 1,036
    • Genes: 1,379
    • CNVs/SVs: 5,420
    • SNVs/Indels: 11,669
    • de novo Mutations: 5,669
    • Mosaics: 789
    • Linkage Regions: 172
    • Paper Collected: 6/30/2018
    • Last Update: 8/26/2018


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