AutismKB 2.0

Annotation Detail for ADCY10


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Basic Information Top
Gene Symbol:ADCY10 ( HCA2,RP1-313L4.2,SAC,SACI,Sacy )
Gene Full Name: adenylate cyclase 10 (soluble)
Band: 1q24.2
Quick LinksEntrez ID:55811; OMIM: 605205; Uniprot ID:ADCYA_HUMAN; ENSEMBL ID: ENSG00000143199; HGNC ID: 21285
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
No data
Pathway IDPathway Name
hsa00230Purine metabolism
No data
No data
Pathway IDPathway Name
P00039Metabotropic glutamate receptor group III pathway
P00019Endothelin signaling pathway
P00040Metabotropic glutamate receptor group II pathway
P00043Muscarinic acetylcholine receptor 2 and 4 signaling pathway
No data
Related Diseases/Disorders Top
No data
No data
No data
No data
Desease Name
Hypercalciuria, absorptive, susceptibility to
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
D000643 Ammonium Chloride Ammonium Chloride affects the expression of ADCY10 mRNAaffects expression 16483693
D005419 Flavonoids Flavonoids results in increased expression of ADCY10 mRNAincreases expression 18035473
C023036 perfluorooctanoic acid perfluorooctanoic acid results in increased expression of ADCY10 mRNAincreases expression 16221955
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000138 Acidosis Ammonium Chloride 4.3018287403
MESH:D004487 Edema perfluorooctanoic acid 4.0617259670 12083418
MESH:D006529 Hepatomegaly perfluorooctanoic acid 4.753609246
MESH:D006930 Hyperalgesia perfluorooctanoic acid 4.2112083418
OMIM:143870 HYPERCALCIURIA, ABSORPTIVE, 2 marker/mechanism
MESH:D007249 Inflammation Flavonoids 6.1017296493
MESH:D007249 Inflammation perfluorooctanoic acid 6.1012083418
MESH:D007984 Leydig Cell Tumor perfluorooctanoic acid 5.978812269
MESH:D008113 Liver Neoplasms perfluorooctanoic acid 3.0414757943 18709148
MESH:D052556 Niemann-Pick Disease, Type C perfluorooctanoic acid 5.619802331
MESH:D011297 Prenatal Exposure Delayed Effects perfluorooctanoic acid 5.1417132714
Pathway ID Pathway Name
KEGG:00230 Purine metabolism
Pharmacogenomics Knowledge Base Top
Drug Bank Top

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  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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