Annotation Detail for KDM3A
Basic Information Top
| Gene Symbol: | KDM3A ( DKFZp686A24246,DKFZp686P07111,JHDM2A,JHMD2A,JMJD1,JMJD1A,KIAA0742,TSGA ) |
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| Gene Full Name: | lysine (K)-specific demethylase 3A |
| Band: | 2p11.2 |
| Quick Links | Entrez ID:55818; OMIM: 611512; Uniprot ID:KDM3A_HUMAN; ENSEMBL ID: ENSG00000115548; HGNC ID: 20815 |
| Relate to Another Database: | SFARIGene; denovo-db |
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| Pathway ID | Pathway Name |
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| 200038 | Coregulation of Androgen receptor activity |
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| Chemical ID | Chemical Name | Interaction | Interaction Action | Publication |
|---|---|---|---|---|
| D000082 | Acetaminophen | MAP3K5 protein affects the reaction [Acetaminophen results in increased expression of KDM3A mRNA] | affects reaction|increases expression | 18700144 |
| D000643 | Ammonium Chloride | Ammonium Chloride affects the expression of KDM3A mRNA | affects expression | 16483693 |
| Disease ID | Disease Name | Direct Evidence | Inference Chemical Name | Inference Score | Publication |
|---|---|---|---|---|---|
| MESH:D000138 | Acidosis | Ammonium Chloride | 4.44 | 18287403 | |
| MESH:D000799 | Angioedema | Acetaminophen | 4.91 | 10982225 | |
| MESH:D001321 | Autistic Disorder | Acetaminophen | 1.39 | 18445737 | |
| MESH:D006528 | Carcinoma, Hepatocellular | Acetaminophen | 1.41 | 3084413 | |
| MESH:D002386 | Cataract | Acetaminophen | 2.83 | 10977129 | |
| MESH:D056486 | Drug-Induced Liver Injury | Acetaminophen | 1.68 | 19164858 10663392 16393943 15619225 16485898 11287661 17562736 19739265 19370779 11529661 12594235 19923254 16081117 14550746 16109766 18713872 15968718 12153990 17906064 2444490 11834606 11739529 12705907 12392966 10915739 19420014 14725611 11743745 11421492 10774834 16227642 12540782 18071297 16781746 11461765 14986274 17522070 16177239 12958197 19085960 19416960 | |
| MESH:D056487 | Drug-Induced Liver Injury, Chronic | Acetaminophen | 5.17 | 19426721 | |
| MESH:D005756 | Gastritis | Acetaminophen | 4.74 | 16983495 | |
| MESH:D006930 | Hyperalgesia | Acetaminophen | 3.11 | 16870215 | |
| MESH:D007674 | Kidney Diseases | Acetaminophen | 2.44 | 12587719 15629191 | |
| MESH:D008107 | Liver Diseases | Acetaminophen | 1.71 | 19460945 16611625 19014921 11587558 19784758 12587719 12969438 16610002 | |
| MESH:D017114 | Liver Failure, Acute | Acetaminophen | 3.74 | 17185352 16871587 | |
| MESH:D008546 | Melanoma, Experimental | Acetaminophen | 4.33 | 19513568 | |
| MESH:D019636 | Neurodegenerative Diseases | Acetaminophen | 3.31 | 18514411 | |
| MESH:D010146 | Pain | Acetaminophen | 2.82 | 16870215 | |
| MESH:D014581 | Urticaria | Acetaminophen | 3.58 | 10982225 |
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