AutismKB 2.0

Annotation Detail for LMO3


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Basic Information Top
Gene Symbol:LMO3 ( DAT1,MGC26081,RBTN3,RBTNL2,RHOM3,Rhom-3 )
Gene Full Name: LIM domain only 3 (rhombotin-like 2)
Band: 12p12.3
Quick LinksEntrez ID:55885; OMIM: 180386; Uniprot ID:LMO3_HUMAN; ENSEMBL ID: ENSG00000048540; HGNC ID: 6643
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
Related Diseases/Disorders Top
No data
Desease IDDesease Name
1856Obesity
1986Eating disorder
2151Neuroblastoma
2190Attention deficit hyperactivity disorder
No data
No data
No data
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C006780 bisphenol A bisphenol A affects the expression of LMO3 mRNAaffects expression 20170705
D004997 Ethinyl Estradiol Ethinyl Estradiol affects the expression of LMO3 mRNAaffects expression 20170705
C025643 vinclozolin vinclozolin affects the expression of LMO3 mRNAaffects expression 19015723
D014810 Vitamin E Vitamin E results in increased expression of LMO3 mRNAincreases expression 19244175
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000152 Acne Vulgaris Ethinyl Estradiol 4.6617505938
MESH:D000230 Adenocarcinoma Ethinyl Estradiol 1.8814692618
MESH:D001008 Anxiety Disorders vinclozolin 3.9719015723
MESH:D001161 Arteriosclerosis Ethinyl Estradiol 4.0211256880
MESH:D001169 Arthritis, Experimental Ethinyl Estradiol 2.8915885639
MESH:D001862 Bone Resorption bisphenol A 4.2911985600
MESH:D001943 Breast Neoplasms bisphenol A 2.4317123778
MESH:D002252 Carbon Tetrachloride Poisoning Vitamin E 4.4916050911
MESH:D002278 Carcinoma in Situ bisphenol A 5.6217123778
MESH:D002779 Cholestasis Ethinyl Estradiol 3.1716105132 15861022 17681005 17333356 16919318 17110522 11677210
MESH:D019465 Craniofacial Abnormalities Vitamin E 1.9319769572
MESH:D003456 Cryptorchidism vinclozolin 4.8514966744
MESH:C538011 Eales disease Vitamin E 5.439068938
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Ethinyl Estradiol 3.6912538720
MESH:D005234 Fatty Liver Ethinyl Estradiol 3.2415345470
MESH:D030342 Genetic Diseases, Inborn vinclozolin 5.5716973722
MESH:D005832 Genital Diseases, Male vinclozolin 6.0216417039
MESH:D006330 Heart Defects, Congenital Vitamin E 3.1716080930
MESH:D006548 Hernia, Diaphragmatic Vitamin E 2.8116490937 16863852
MESH:D019584 Hot Flashes Vitamin E 4.6914716179
MESH:D007021 Hypospadias Ethinyl Estradiol 4.3716945680 16569931
MESH:D007247 Infertility, Female Ethinyl Estradiol 3.9212013081
MESH:D007248 Infertility, Male Ethinyl Estradiol 7.5117937319
MESH:D007248 Infertility, Male vinclozolin 7.5116467254
MESH:D007251 Influenza, Human Vitamin E 4.9416624496
MESH:D007333 Insulin Resistance bisphenol A 3.5316393666
MESH:D007674 Kidney Diseases Vitamin E 3.0012488133
MESH:D007984 Leydig Cell Tumor vinclozolin 5.3616417039
MESH:D008106 Liver Cirrhosis, Experimental Vitamin E 1.9116169303
MESH:D008171 Lung Diseases Vitamin E 3.4316863852
MESH:D008175 Lung Neoplasms Vitamin E 1.9011062179
MESH:D009421 Nervous System Malformations bisphenol A 4.4816427766 11399458
MESH:D010049 Ovarian Diseases bisphenol A 5.6211985600
MESH:D016584 Panic Disorder Ethinyl Estradiol 4.1511578682
MESH:D011297 Prenatal Exposure Delayed Effects bisphenol A 11.9610548101
MESH:D011297 Prenatal Exposure Delayed Effects vinclozolin 11.9618220299 19015723 18042343
MESH:D011469 Prostatic Diseases vinclozolin 5.5718220299
MESH:D019048 Prostatic Intraepithelial Neoplasia bisphenol A 4.6320887781
MESH:D011471 Prostatic Neoplasms bisphenol A 3.2716740699
MESH:D011471 Prostatic Neoplasms Vitamin E 3.2715084515
MESH:D011472 Prostatitis vinclozolin 5.5718629315
MESH:D011537 Pruritus Ethinyl Estradiol 3.9416919318 15861022
MESH:D011629 Puberty, Precocious bisphenol A 5.4210548101
MESH:D012871 Skin Diseases Vitamin E 2.5218709164
MESH:D013088 Spermatocele Ethinyl Estradiol 4.6616709447
MESH:D020521 Stroke Vitamin E 3.8416517955
MESH:D019966 Substance-Related Disorders bisphenol A 4.6116684133 16045194
MESH:D019851 Thrombophilia Ethinyl Estradiol 4.0811994571
MESH:D013927 Thrombosis Ethinyl Estradiol 3.5215669648
MESH:D014591 Uterine Diseases bisphenol A 5.7314652134
MESH:D014594 Uterine Neoplasms Ethinyl Estradiol 3.8014692618
MESH:D020246 Venous Thrombosis Ethinyl Estradiol 3.9714671159 15869587
No data
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Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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