AutismKB 2.0

Annotation Detail for MYO5C


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Basic Information Top
Gene Symbol:MYO5C ( MGC74969 )
Gene Full Name: myosin VC
Band: 15q21.2
Quick LinksEntrez ID:55930; OMIM: 610022; Uniprot ID:MYO5C_HUMAN; ENSEMBL ID: ENSG00000128833; HGNC ID: 7604
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
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Pathway IDPathway Name
P00044Nicotinic acetylcholine receptor signaling pathway
No data
Related Diseases/Disorders Top
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
D001564 Benzo(a)pyrene Benzo(a)pyrene results in decreased expression of MYO5C mRNAdecreases expression 20106945
D020122 tert-Butylhydroperoxide tert-Butylhydroperoxide results in decreased expression of MYO5C mRNAdecreases expression 15336504
D004041 Dietary Fats Dietary Fats results in increased expression of MYO5C mRNAincreases expression 18042831
C041786 palm oil palm oil results in increased expression of MYO5C mRNAincreases expression 18042831
D011794 Quercetin Quercetin results in decreased expression of MYO5C mRNAdecreases expression 18095365
C025643 vinclozolin vinclozolin affects the expression of MYO5C mRNAaffects expression 19015723
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000230 Adenocarcinoma Benzo(a)pyrene 2.0420127859 20464547
MESH:D000236 Adenoma Benzo(a)pyrene 2.826695378
MESH:D000743 Anemia, Hemolytic Quercetin 4.5717084956
MESH:D001008 Anxiety Disorders vinclozolin 3.8919015723
MESH:D017544 Aortic Aneurysm, Abdominal Benzo(a)pyrene 4.4919183758
MESH:D001161 Arteriosclerosis Dietary Fats 4.3115238619
MESH:D001260 Ataxia Telangiectasia Quercetin 5.4415336622
MESH:D001327 Autoimmune Diseases Quercetin 4.8219761891
MESH:D001943 Breast Neoplasms Benzo(a)pyrene 1.9320146248 17474063
MESH:D001943 Breast Neoplasms Dietary Fats 1.9320435547
MESH:D001943 Breast Neoplasms Quercetin 1.9318628248
MESH:D002105 Cadmium Poisoning Quercetin 6.0716962696
MESH:D006528 Carcinoma, Hepatocellular Quercetin 2.3019519916 12508355
MESH:D021441 Carcinoma, Pancreatic Ductal Quercetin 5.3717234771
MESH:D002294 Carcinoma, Squamous Cell Benzo(a)pyrene 2.1220419170
MESH:D006332 Cardiomegaly Quercetin 3.4719794523
MESH:D003110 Colonic Neoplasms Quercetin 2.4611134977 19440933 16640504 19056647 17191121 17148506 15741050
MESH:D015179 Colorectal Neoplasms Quercetin 2.1918852136 18095365
MESH:D003456 Cryptorchidism vinclozolin 4.7214966744
MESH:D003921 Diabetes Mellitus, Experimental Quercetin 4.0019496084
MESH:D050171 Dyslipidemias Dietary Fats 3.6718367378
MESH:D004938 Esophageal Neoplasms Benzo(a)pyrene 2.0716530937
MESH:D005234 Fatty Liver Dietary Fats 3.5619551842 17967931 18296743 19004024
MESH:D005355 Fibrosis Dietary Fats 10.4018296743
MESH:D005355 Fibrosis Quercetin 10.4019474275
MESH:D030342 Genetic Diseases, Inborn vinclozolin 5.4016973722
MESH:D005832 Genital Diseases, Male vinclozolin 5.8216417039
MESH:D005909 Glioblastoma Quercetin 3.5819804834
MESH:D005910 Glioma Quercetin 3.1517643826
MESH:D006330 Heart Defects, Congenital Benzo(a)pyrene 2.8020471113
MESH:D006937 Hypercholesterolemia Dietary Fats 3.9221332399
MESH:D006943 Hyperglycemia Quercetin 4.3418262572 11834736
MESH:D006949 Hyperlipidemias Dietary Fats 3.9721332399
MESH:D006973 Hypertension Quercetin 2.9518356687
MESH:D007248 Infertility, Male vinclozolin 3.2416467254
MESH:D007249 Inflammation Dietary Fats 2.5720412841
MESH:D007251 Influenza, Human Quercetin 5.0316624496
MESH:D007333 Insulin Resistance Dietary Fats 3.3011836018 18457598
MESH:D007627 Keloid Quercetin 5.3717086741
MESH:D007674 Kidney Diseases Quercetin 3.2616962696
MESH:D007938 Leukemia Quercetin 3.2917468513
MESH:D007984 Leydig Cell Tumor vinclozolin 5.1916417039
MESH:D008103 Liver Cirrhosis Dietary Fats 3.0318296743
MESH:D008106 Liver Cirrhosis, Experimental Quercetin 2.2012741479
MESH:D008113 Liver Neoplasms Benzo(a)pyrene 5.0120195826 21137059
MESH:D008113 Liver Neoplasms Quercetin 5.0118980244
MESH:D008114 Liver Neoplasms, Experimental Quercetin 3.2419519916
MESH:D008175 Lung Neoplasms Benzo(a)pyrene 2.6018816296 20064080 20464547 6695378 20135361 17053015 18520028 18569708 20869020
MESH:D008175 Lung Neoplasms Quercetin 2.6016280456
MESH:D009062 Mouth Neoplasms Benzo(a)pyrene 3.4316381670
MESH:D009203 Myocardial Infarction Quercetin 3.1019595682
MESH:D015428 Myocardial Reperfusion Injury Quercetin 4.0319207477
MESH:D009369 Neoplasms Benzo(a)pyrene 5.5911141357
MESH:D009369 Neoplasms Quercetin 5.5915185748
MESH:D020078 Neurogenic Inflammation Quercetin 4.7117929310
MESH:D009765 Obesity Dietary Fats 2.3419632207 17217161 20132043 20518802 18674790 11836018 16723640 18457598 21332399
MESH:D015663 Osteoporosis, Postmenopausal Quercetin 4.5719495926
MESH:D010051 Ovarian Neoplasms Quercetin 2.8119005980
MESH:D010190 Pancreatic Neoplasms Quercetin 2.9416965848
MESH:D011230 Precancerous Conditions Quercetin 4.2719056647
MESH:D011297 Prenatal Exposure Delayed Effects vinclozolin 4.3619015723 18042343 18220299
MESH:D011469 Prostatic Diseases vinclozolin 5.4018220299
MESH:D011471 Prostatic Neoplasms Benzo(a)pyrene 3.2317292933
MESH:D011471 Prostatic Neoplasms Quercetin 3.2314715546 17292933
MESH:D011472 Prostatitis vinclozolin 5.4018629315
MESH:D012554 Schistosomiasis japonica Quercetin 6.0716862918
MESH:D012878 Skin Neoplasms Benzo(a)pyrene 6.1419755658 10029692
MESH:D012878 Skin Neoplasms tert-Butylhydroperoxide 6.148532709
MESH:D013274 Stomach Neoplasms Benzo(a)pyrene 1.562093021 20155912
MESH:D001749 Urinary Bladder Neoplasms Benzo(a)pyrene 5.5117053015
MESH:D001749 Urinary Bladder Neoplasms Quercetin 5.5116720314
MESH:D015430 Weight Gain Dietary Fats 4.0216723640
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Pharmacogenomics Knowledge Base Top
  • PharmGKB Accession:PA31409
    • No data
    Releated disease ID Related disease Name
    PA446155Precursor Cell Lymphoblastic Leukemia-Lymphoma
    No data
    Drug Bank Top

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    Syndromic Genes

    Non-syndromic Genes

    AutismKB Statistics

    • Studies: 1,036
    • Genes: 1,379
    • CNVs/SVs: 5,420
    • SNVs/Indels: 11,669
    • de novo Mutations: 5,669
    • Mosaics: 789
    • Linkage Regions: 172
    • Paper Collected: 6/30/2018
    • Last Update: 8/26/2018


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