AutismKB 2.0

Annotation Detail for APOM


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Basic Information Top
Gene Symbol:APOM ( G3a,HSPC336,MGC22400,NG20 )
Gene Full Name: apolipoprotein M
Band: 6p21.33
Quick LinksEntrez ID:55937; OMIM: 606907; Uniprot ID:APOM_HUMAN; ENSEMBL ID: ENSG00000204444; HGNC ID: 13916
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
Related Diseases/Disorders Top
No data
Desease IDDesease Name
1740Alzheimer's disease
1904Diabetes mellitus
1918Atherosclerosis
2052Infection
Desease Name
CANCER
lung adenocarcinoma
METABOLIC
diabetes, type 2
No data
No data
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C023514 2,6-dinitrotoluene 2,6-dinitrotoluene affects the expression of APOM mRNAaffects expression 21346803
D000643 Ammonium Chloride Ammonium Chloride affects the expression of APOM mRNAaffects expression 16483693
D001104 Arbutin Arbutin results in increased expression of APOM mRNAincreases expression 17103032
D001205 Ascorbic Acid [Quercetin co-treated with Ascorbic Acid] results in decreased expression of APOM mRNAaffects cotreatment|decreases expression 17639512
D019324 beta-Naphthoflavone [Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of APOM mRNAaffects cotreatment|decreases expression 18164116
C032036 bromobenzene bromobenzene results in increased expression of APOM mRNAincreases expression 12628495
D002118 Calcium Calcium affects the expression of APOM mRNAaffects expression 15913539
D016572 Cyclosporine Cyclosporine results in decreased expression of APOM mRNAdecreases expression 20106945
D004041 Dietary Fats Dietary Fats results in decreased expression of APOM mRNAdecreases expression 15238619
D004052 Diethylnitrosamine [Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of APOM mRNAaffects cotreatment|decreases expression 18164116
D004052 Diethylnitrosamine Diethylnitrosamine results in decreased expression of APOM mRNAdecreases expression 19638242
D004958 Estradiol [Progesterone co-treated with Estradiol] results in increased expression of APOM mRNAaffects cotreatment|increases expression 17404688
D004997 Ethinyl Estradiol [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of APOM mRNAaffects cotreatment|increases expression 17942748
D008070 Lipopolysaccharides Lipopolysaccharides results in decreased expression of APOM mRNAdecreases expression 18054359
D008070 Lipopolysaccharides Lipopolysaccharides results in decreased expression of APOM proteindecreases expression 18054359
C006253 pirinixic acid [pirinixic acid binds to and results in increased activity of PPARA protein] which results in decreased expression of APOM mRNAaffects binding|decreases expression|increases activity 19710929
C006253 pirinixic acid pirinixic acid results in decreased expression of APOM mRNAdecreases expression 15375163
D011374 Progesterone [Progesterone co-treated with Estradiol] results in increased expression of APOM mRNAaffects cotreatment|increases expression 17404688
D011794 Quercetin [Quercetin co-treated with Ascorbic Acid] results in decreased expression of APOM mRNAaffects cotreatment|decreases expression 17639512
C021751 tanshinone tanshinone results in increased expression of APOM mRNAincreases expression 15849732
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in increased expression of APOM mRNAincreases expression 19684285
D013749 Tetrachlorodibenzodioxin [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of APOM mRNAaffects cotreatment|increases expression 17942748
D014212 Tretinoin Tretinoin results in decreased expression of APOM mRNAdecreases expression 18230668
D014425 Turpentine Turpentine results in decreased expression of APOM mRNAdecreases expression 18054359
D014810 Vitamin E Vitamin E results in increased expression of APOM mRNAincreases expression 19244175
D015054 Zymosan Zymosan results in decreased expression of APOM mRNAdecreases expression 18054359
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000014 Abnormalities, Drug-Induced Tetrachlorodibenzodioxin 2.7215322242 11752688 14514962
MESH:D000138 Acidosis Ammonium Chloride 3.4318287403
MESH:D000152 Acne Vulgaris Ethinyl Estradiol 3.8117505938
MESH:D055371 Acute Lung Injury Lipopolysaccharides 8.6311850527 18653653
MESH:D055371 Acute Lung Injury pirinixic acid 8.6318653653
MESH:D000210 Acute-Phase Reaction Turpentine 6.0416044259
MESH:D000230 Adenocarcinoma Estradiol 4.1111473722
MESH:D000230 Adenocarcinoma Ethinyl Estradiol 4.1114692618
MESH:D000236 Adenoma beta-Naphthoflavone 6.6319389873
MESH:D000236 Adenoma Diethylnitrosamine 6.636695378 10737359
MESH:D018248 Adenoma, Liver Cell Diethylnitrosamine 16.5217620307 19061943 18056438 16434500 17162532 19052882
MESH:D018248 Adenoma, Liver Cell pirinixic acid 16.5216434500
MESH:D018248 Adenoma, Liver Cell Tetrachlorodibenzodioxin 16.5216835633
MESH:D000505 Alopecia Tretinoin 3.5115955085
MESH:D000740 Anemia Tetrachlorodibenzodioxin 8.6011748828
MESH:D000740 Anemia Zymosan 8.6018664788
MESH:D000743 Anemia, Hemolytic Quercetin 4.1217084956
MESH:D001161 Arteriosclerosis Dietary Fats 9.4715238619
MESH:D001161 Arteriosclerosis Ethinyl Estradiol 9.4711256880
MESH:D001169 Arthritis, Experimental Ethinyl Estradiol 11.8915885639
MESH:D001169 Arthritis, Experimental Tretinoin 11.8916412693
MESH:D001169 Arthritis, Experimental Zymosan 11.8916872482 15142272 15944321 15188379 17659584
MESH:D001172 Arthritis, Rheumatoid Tretinoin 2.2316292516
MESH:D001249 Asthma Tretinoin 2.3116456186
MESH:D001260 Ataxia Telangiectasia Quercetin 4.8515336622
MESH:D001327 Autoimmune Diseases Quercetin 4.2819761891
MESH:D001471 Barrett Esophagus Tretinoin 4.2716935849
MESH:D001778 Blood Coagulation Disorders pirinixic acid 14.5719483382
MESH:D001778 Blood Coagulation Disorders Tetrachlorodibenzodioxin 14.5712125929
MESH:D001778 Blood Coagulation Disorders Tretinoin 14.5716206674 16197459
MESH:D001836 Body Weight Changes Tetrachlorodibenzodioxin 3.6615340226
MESH:D001848 Bone Diseases, Developmental Tetrachlorodibenzodioxin 2.6815746008
MESH:D020201 Brain Hemorrhage, Traumatic Progesterone 5.2117868700
MESH:D001930 Brain Injuries Progesterone 4.1315845082 15665606 15380490
MESH:D001943 Breast Neoplasms Ascorbic Acid 5.7116443354
MESH:D001943 Breast Neoplasms Dietary Fats 5.7120435547
MESH:D001943 Breast Neoplasms Diethylnitrosamine 5.7117474063
MESH:D001943 Breast Neoplasms Estradiol 5.7116675129 12948864 14630087 18497071 17261762 17289903 19861407 17018787
MESH:D001943 Breast Neoplasms Progesterone 5.7116175315 17614352 15562024
MESH:D001943 Breast Neoplasms Quercetin 5.7118628248
MESH:D001943 Breast Neoplasms tanshinone 5.7119885617 15849732
MESH:D001943 Breast Neoplasms Tetrachlorodibenzodioxin 5.7120435547
MESH:D001943 Breast Neoplasms Tretinoin 5.7116166294 16443354 16873071
MESH:D001997 Bronchopulmonary Dysplasia Tretinoin 4.4616813970
MESH:D002105 Cadmium Poisoning Quercetin 5.4216962696
MESH:D002181 Candidiasis, Vulvovaginal Estradiol 4.3316111702
MESH:D002252 Carbon Tetrachloride Poisoning Vitamin E 3.8016050911
MESH:D002277 Carcinoma Tetrachlorodibenzodioxin 2.6916835633
MESH:D018236 Carcinoma, Embryonal Tretinoin 5.0316168501
MESH:D006528 Carcinoma, Hepatocellular 2,6-dinitrotoluene 8.6516705839
MESH:D006528 Carcinoma, Hepatocellular Diethylnitrosamine 8.6517173139 18971187 19519916 21159647 18785209 16698587 18393292 16779866 17138121 11831363 18506893 19822196 16807293 18665156 3084413 17162532 20935162 20101231 19171122 10737359 17761372 19418558 17055752 16540662 18210153 20512989 19335982 19107877 17428255 19383236 20084675 20007298 3581430 18978308 20514400 18494052 19539802 20524982 19052882 16830150 19701751 16502159 16288022 16681979 19394651 19208518 10672840 16328049 17978847 18788625 18056438 18691550 20432363 20727157 16935385 19919837 20214788 16569478 16878318
MESH:D006528 Carcinoma, Hepatocellular Estradiol 8.6516924424
MESH:D006528 Carcinoma, Hepatocellular Quercetin 8.6519519916 12508355
MESH:D006528 Carcinoma, Hepatocellular Tretinoin 8.651917145
MESH:D021441 Carcinoma, Pancreatic Ductal Quercetin 4.8217234771
MESH:D002294 Carcinoma, Squamous Cell Tretinoin 2.2516096774 16051514
MESH:D006332 Cardiomegaly Quercetin 6.5619794523
MESH:D006332 Cardiomegaly Tetrachlorodibenzodioxin 6.5618670907 18850075 16120746
MESH:D002386 Cataract Tretinoin 3.0217460283
MESH:D002471 Cell Transformation, Neoplastic 2,6-dinitrotoluene 15.276135515
MESH:D002471 Cell Transformation, Neoplastic Cyclosporine 15.2712371664
MESH:D002471 Cell Transformation, Neoplastic Diethylnitrosamine 15.2717174075 7505956 21159647 2727394
MESH:D002471 Cell Transformation, Neoplastic Estradiol 15.2718566989
MESH:D018290 Cervical Intraepithelial Neoplasia Tretinoin 4.4616129372
MESH:D018281 Cholangiocarcinoma Diethylnitrosamine 8.9519052882
MESH:D018281 Cholangiocarcinoma Tetrachlorodibenzodioxin 8.9516835633
MESH:D002779 Cholestasis Cyclosporine 12.7819486331
MESH:D002779 Cholestasis Ethinyl Estradiol 12.7815861022 11677210 17110522 16105132 17333356 17681005 16919318
MESH:D002779 Cholestasis pirinixic acid 12.7819176532
MESH:D002822 Choriocarcinoma Tretinoin 5.0316461808
MESH:D002972 Cleft Palate Tetrachlorodibenzodioxin 5.5815340226 16354765 15668235 8697196 12621046
MESH:D002972 Cleft Palate Tretinoin 5.589407595
MESH:D003092 Colitis Tretinoin 3.5717035595
MESH:D003110 Colonic Neoplasms Quercetin 2.4011134977 17191121 15741050 19056647 16640504 17148506 19440933
MESH:D015179 Colorectal Neoplasms Quercetin 2.1818852136 18095365
MESH:D003139 Common Cold Ascorbic Acid 5.3517323712
MESH:D000013 Congenital Abnormalities Tetrachlorodibenzodioxin 2.9514669216 17141729
MESH:D019465 Craniofacial Abnormalities Tetrachlorodibenzodioxin 3.6815322242 20055451 10048152
MESH:D019465 Craniofacial Abnormalities Tretinoin 3.689224671 9664655 16925845 14991402 9211117 9125849 9142499 10589399 8800419 17551590
MESH:D019465 Craniofacial Abnormalities Vitamin E 3.6819769572
MESH:D003490 Cyanosis 2,6-dinitrotoluene 3.8918551238
MESH:D003876 Dermatitis, Atopic pirinixic acid 2.3718249437
MESH:D003921 Diabetes Mellitus, Experimental Quercetin 3.6219496084
MESH:D003924 Diabetes Mellitus, Type 2 Ascorbic Acid 7.0016506275
MESH:D003924 Diabetes Mellitus, Type 2 Diethylnitrosamine 7.0020387270
MESH:D003924 Diabetes Mellitus, Type 2 Tetrachlorodibenzodioxin 7.0017107852
MESH:D003928 Diabetic Nephropathies Estradiol 3.3019279558
MESH:D003929 Diabetic Neuropathies Progesterone 4.3617187935
MESH:D056486 Drug-Induced Liver Injury 2,6-dinitrotoluene 8.7021346803 18551238
MESH:D056486 Drug-Induced Liver Injury bromobenzene 8.7012628495 10092053
MESH:D056486 Drug-Induced Liver Injury Diethylnitrosamine 8.7019107877
MESH:D056486 Drug-Induced Liver Injury Tetrachlorodibenzodioxin 8.7020420201
MESH:D004362 Drug Toxicity Tetrachlorodibenzodioxin 2.6611462148
MESH:D050171 Dyslipidemias Dietary Fats 3.3618367378
MESH:C538011 Eales disease Ascorbic Acid 12.649068938
MESH:C538011 Eales disease Vitamin E 12.649068938
MESH:D004487 Edema pirinixic acid 10.8212083418
MESH:D004487 Edema Tetrachlorodibenzodioxin 10.8212711302 11000095
MESH:D004487 Edema Zymosan 10.827907874
MESH:D004489 Edema, Cardiac Tetrachlorodibenzodioxin 11.5116714409 18230668 15322242
MESH:D004489 Edema, Cardiac Tretinoin 11.5118230668
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Ethinyl Estradiol 8.6112538720
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Progesterone 8.6117692515
MESH:D016889 Endometrial Neoplasms Estradiol 7.1319148513 11473722 18566989
MESH:D016889 Endometrial Neoplasms Tretinoin 7.1316569247
MESH:D004715 Endometriosis Progesterone 8.5416134523
MESH:D004715 Endometriosis Tetrachlorodibenzodioxin 8.549294722 10568697
MESH:D019446 Endotoxemia Lipopolysaccharides 4.2617637181 15328337 15821434
MESH:D004931 Esophageal Achalasia Diethylnitrosamine 4.9916302075
MESH:D005124 Eye Abnormalities Tetrachlorodibenzodioxin 8.5111564622
MESH:D005124 Eye Abnormalities Tretinoin 8.5116938888 9664655
MESH:D005234 Fatty Liver Cyclosporine 23.3519224547
MESH:D005234 Fatty Liver Dietary Fats 23.3518296743 19004024 19551842 17967931
MESH:D005234 Fatty Liver Diethylnitrosamine 23.3521071580 20387270
MESH:D005234 Fatty Liver Ethinyl Estradiol 23.3515345470
MESH:D005234 Fatty Liver pirinixic acid 23.3520131406 19236843
MESH:D005313 Fetal Death Tetrachlorodibenzodioxin 3.3311858732
MESH:D005334 Fever Lipopolysaccharides 3.909205823 11852909
MESH:D005355 Fibrosis Cyclosporine 26.3512168785 12639820
MESH:D005355 Fibrosis Dietary Fats 26.3518296743
MESH:D005355 Fibrosis Quercetin 26.3519474275
MESH:D005355 Fibrosis Tetrachlorodibenzodioxin 26.3520067830
MESH:D005355 Fibrosis Tretinoin 26.3517994277
MESH:D005885 Gingival Hyperplasia Cyclosporine 4.098708960
MESH:D005909 Glioblastoma Quercetin 6.9719804834
MESH:D005909 Glioblastoma Tretinoin 6.9717312396
MESH:D005910 Glioma Quercetin 6.4417643826
MESH:D005910 Glioma tanshinone 6.4416955220
MESH:D006058 Gonadal Disorders Tetrachlorodibenzodioxin 4.4710696789
MESH:D006258 Head and Neck Neoplasms Tretinoin 3.1016096774
MESH:D006317 Hearing Loss, Noise-Induced Tretinoin 5.0316084493
MESH:D006330 Heart Defects, Congenital Ascorbic Acid 15.4616080930
MESH:D006330 Heart Defects, Congenital Tetrachlorodibenzodioxin 15.4611294989 10048152
MESH:D006330 Heart Defects, Congenital Tretinoin 15.4614991402 9664655
MESH:D006330 Heart Defects, Congenital Vitamin E 15.4616080930
MESH:D006333 Heart Failure pirinixic acid 2.4620558911
MESH:D006457 Hemoglobinuria, Paroxysmal Cyclosporine 4.2915720958
MESH:D006463 Hemolytic-Uremic Syndrome Lipopolysaccharides 4.2716366002
MESH:D006470 Hemorrhage Tetrachlorodibenzodioxin 3.2111000095
MESH:D006505 Hepatitis Zymosan 4.5719110552
MESH:D006529 Hepatomegaly pirinixic acid 7.8319176532 18467677 19772884 16221962
MESH:D006529 Hepatomegaly Tetrachlorodibenzodioxin 7.8312621046 15340226 16120746
MESH:D006548 Hernia, Diaphragmatic Ascorbic Acid 5.9716863852 16490937
MESH:D006548 Hernia, Diaphragmatic Vitamin E 5.9716863852 16490937
MESH:D006558 Herpes Genitalis Estradiol 4.9015709030
MESH:D019584 Hot Flashes Estradiol 9.6217088409
MESH:D019584 Hot Flashes Vitamin E 9.6214716179
MESH:D006869 Hydronephrosis Tetrachlorodibenzodioxin 3.928697196 18606429 16959395 15340226 16354765
MESH:D006930 Hyperalgesia Tretinoin 3.1116870215
MESH:D006937 Hypercholesterolemia Dietary Fats 3.4721332399
MESH:D017681 Hypereosinophilic Syndrome Tretinoin 4.4416778211
MESH:D006943 Hyperglycemia pirinixic acid 8.8520558911
MESH:D006943 Hyperglycemia Quercetin 8.8518262572 11834736
MESH:D006949 Hyperlipidemias Dietary Fats 3.4921332399
MESH:D006973 Hypertension Cyclosporine 8.2910903974
MESH:D006973 Hypertension Quercetin 8.2918356687
MESH:D006973 Hypertension Tetrachlorodibenzodioxin 8.2918850075 18670907
MESH:D017379 Hypertrophy, Left Ventricular tanshinone 5.1219662366
MESH:D007021 Hypospadias Ethinyl Estradiol 3.6816945680 16569931
MESH:D020244 Infarction, Middle Cerebral Artery Progesterone 4.2715869954
MESH:D007247 Infertility, Female Ethinyl Estradiol 3.3412013081
MESH:D007248 Infertility, Male Ethinyl Estradiol 2.4017937319
MESH:D007249 Inflammation Dietary Fats 19.1020412841
MESH:D007249 Inflammation Diethylnitrosamine 19.1018785209
MESH:D007249 Inflammation Lipopolysaccharides 19.1017255318 12878042 17237260 9205823 17963957
MESH:D007249 Inflammation Progesterone 19.1015869954
MESH:D007249 Inflammation Tetrachlorodibenzodioxin 19.1012200463 12878042
MESH:D007249 Inflammation Zymosan 19.1011289658 8014878
MESH:D007251 Influenza, Human Quercetin 10.6416624496
MESH:D007251 Influenza, Human Vitamin E 10.6416624496
MESH:D007333 Insulin Resistance Dietary Fats 11.8011836018 18457598
MESH:D007333 Insulin Resistance Estradiol 11.8016627594 16393666
MESH:D007333 Insulin Resistance pirinixic acid 11.8016306350
MESH:D007410 Intestinal Diseases Tretinoin 3.6417994277
MESH:D019189 Iron Metabolism Disorders Lipopolysaccharides 4.5117255318
MESH:D043183 Irritable Bowel Syndrome Zymosan 5.7117553498
MESH:D007569 Jaw Abnormalities Tetrachlorodibenzodioxin 9.5316580747
MESH:D007569 Jaw Abnormalities Tretinoin 9.5317551590 15992940
MESH:D007627 Keloid Quercetin 4.8217086741
MESH:D007638 Keratoconjunctivitis Sicca Cyclosporine 4.3115604871
MESH:D007674 Kidney Diseases Cyclosporine 13.8418776723 10903974 8314463
MESH:D007674 Kidney Diseases Estradiol 13.8415618244
MESH:D007674 Kidney Diseases Quercetin 13.8416962696
MESH:D007674 Kidney Diseases Vitamin E 13.8412488133
MESH:D007680 Kidney Neoplasms 2,6-dinitrotoluene 11.7416705839
MESH:D007680 Kidney Neoplasms Cyclosporine 11.7412371664
MESH:D007680 Kidney Neoplasms Estradiol 11.7415610895
MESH:D007683 Kidney Tubular Necrosis, Acute Calcium 4.9216316344
MESH:D007938 Leukemia Quercetin 6.2517468513
MESH:D007938 Leukemia Tretinoin 6.2517143497
MESH:D007951 Leukemia, Myeloid Tretinoin 3.5816932348 19285840 16482212
MESH:D015470 Leukemia, Myeloid, Acute Tretinoin 2.0616294345 19850784 17596541
MESH:D015473 Leukemia, Promyelocytic, Acute Tretinoin 3.0716891316 16823087 17506722 17294898 19075265 17361223 12679006 16788101 15748426 9834237 17368321 17649720 19029980 17712046 16331271 17107899 19225113 19642359 16935935 17339181 16140955 17301526 19035177 16766008 17217047
MESH:D007970 Leukopenia Lipopolysaccharides 4.5715821434
MESH:D017880 Limb Deformities, Congenital Tretinoin 3.219224671
MESH:D008103 Liver Cirrhosis Dietary Fats 6.4018296743
MESH:D008103 Liver Cirrhosis Diethylnitrosamine 6.4018665156 18407596 20032147 18522880 19638242
MESH:D008106 Liver Cirrhosis, Experimental Estradiol 10.6814716833 14659978
MESH:D008106 Liver Cirrhosis, Experimental Lipopolysaccharides 10.6812878042
MESH:D008106 Liver Cirrhosis, Experimental pirinixic acid 10.6815474484
MESH:D008106 Liver Cirrhosis, Experimental Quercetin 10.6812741479
MESH:D008106 Liver Cirrhosis, Experimental Tetrachlorodibenzodioxin 10.6812878042
MESH:D008106 Liver Cirrhosis, Experimental Tretinoin 10.6816248980 18397230
MESH:D008106 Liver Cirrhosis, Experimental Vitamin E 10.6816169303
MESH:D008107 Liver Diseases Diethylnitrosamine 2.0717034775
MESH:D008113 Liver Neoplasms 2,6-dinitrotoluene 17.347678174
MESH:D008113 Liver Neoplasms beta-Naphthoflavone 17.3419389873 21295105
MESH:D008113 Liver Neoplasms Diethylnitrosamine 17.3419256749 18977376 21278145 18978307 18754104 19294768 19499222 21071580 12112319 15175105 19812893 19642983 20452335 2862719 10737359 20118626 19833225 18648771 20405173 20101389 21047994 20501860 9163691 19254457 18644402 2422723 19426721 20583210 12771043 19090486 20492335 19073162 19638242 20434301 20137499 19850985 19690152 19551842 21167192 16942905 19255062 15885732 19996281 19427195
MESH:D008113 Liver Neoplasms pirinixic acid 17.3420007298 15890375 16377806
MESH:D008113 Liver Neoplasms Quercetin 17.3418980244
MESH:D008113 Liver Neoplasms Tetrachlorodibenzodioxin 17.3416984957
MESH:D008114 Liver Neoplasms, Experimental 2,6-dinitrotoluene 22.332876786 2876784 6135515
MESH:D008114 Liver Neoplasms, Experimental Ascorbic Acid 22.3318544905
MESH:D008114 Liver Neoplasms, Experimental beta-Naphthoflavone 22.3318164116
MESH:D008114 Liver Neoplasms, Experimental Diethylnitrosamine 22.3319519916 18093689 19004024 18079962 16267830 18775883 19009564 18544905 17174075 3124819 19539802 17942915 9362446 18282651 17854601 16842330 2563599 21159647 19126423 18308698 18253720 18164116
MESH:D008114 Liver Neoplasms, Experimental Quercetin 22.3319519916
MESH:D008114 Liver Neoplasms, Experimental Tetrachlorodibenzodioxin 22.3312151625
MESH:D008171 Lung Diseases Ascorbic Acid 7.4416863852
MESH:D008171 Lung Diseases Vitamin E 7.4416863852
MESH:D055370 Lung Injury Lipopolysaccharides 3.8821114838
MESH:D008175 Lung Neoplasms Ascorbic Acid 6.4316401635
MESH:D008175 Lung Neoplasms Diethylnitrosamine 6.4320970405 6695378 21163286 20512841
MESH:D008175 Lung Neoplasms Quercetin 6.4316280456
MESH:D008175 Lung Neoplasms Tetrachlorodibenzodioxin 6.4311884234 19555203
MESH:D008175 Lung Neoplasms Vitamin E 6.4311062179
MESH:D008325 Mammary Neoplasms, Experimental Estradiol 5.7816891317 17203775 11807958 11408345
MESH:D008325 Mammary Neoplasms, Experimental Progesterone 5.7811408345 17203775
MESH:D020149 Manganese Poisoning Estradiol 4.3519453300
MESH:D008527 Medulloblastoma Tretinoin 2.7317453147
MESH:D008545 Melanoma Tretinoin 1.9316752155
MESH:D008591 Meningomyelocele Tretinoin 4.2916940565
MESH:D008664 Metal Metabolism, Inborn Errors Cyclosporine 4.6616801185
MESH:D009102 Multiple Organ Failure Zymosan 5.0815834315 15259001 12130978 15213630 15241586 10890648 18160304 12879239 10479408 17724436
MESH:D009135 Muscular Diseases pirinixic acid 3.3816239165
MESH:D009190 Myelodysplastic Syndromes Tretinoin 3.0117596541
MESH:D009203 Myocardial Infarction pirinixic acid 5.5519151258
MESH:D009203 Myocardial Infarction Quercetin 5.5519595682
MESH:D017202 Myocardial Ischemia Tetrachlorodibenzodioxin 2.9112213967
MESH:D015428 Myocardial Reperfusion Injury Estradiol 13.6016810080
MESH:D015428 Myocardial Reperfusion Injury pirinixic acid 13.6016411023
MESH:D015428 Myocardial Reperfusion Injury Quercetin 13.6019207477
MESH:D009336 Necrosis 2,6-dinitrotoluene 3.737678174 18551238
MESH:D009362 Neoplasm Metastasis Diethylnitrosamine 2.523581430 9029167
MESH:D009369 Neoplasms pirinixic acid 7.9017405874
MESH:D009369 Neoplasms Quercetin 7.9015185748
MESH:D009369 Neoplasms Tretinoin 7.9016946489 16594593
MESH:D009389 Neovascularization, Pathologic Estradiol 3.6017289903
MESH:D009402 Nephrosis, Lipoid Cyclosporine 4.3117954296
MESH:D009404 Nephrotic Syndrome Cyclosporine 3.1718481113 19348381
MESH:D009421 Nervous System Malformations Estradiol 15.5916427766 11399458
MESH:D009421 Nervous System Malformations Tetrachlorodibenzodioxin 15.5914600291
MESH:D009421 Nervous System Malformations Tretinoin 15.599125849
MESH:D009436 Neural Tube Defects Tretinoin 2.979142499
MESH:D019636 Neurodegenerative Diseases Diethylnitrosamine 3.2320387270
MESH:D020078 Neurogenic Inflammation Quercetin 4.2417929310
MESH:D009461 Neurologic Manifestations Diethylnitrosamine 4.9920387270
MESH:D009765 Obesity Ascorbic Acid 7.2917217161
MESH:D009765 Obesity Dietary Fats 7.2917217161 20518802 18674790 20132043 19632207 11836018 21332399 16723640 18457598
MESH:D009765 Obesity pirinixic acid 7.2920558911
MESH:D009784 Occupational Diseases 2,6-dinitrotoluene 3.3216049721
MESH:D010024 Osteoporosis Calcium 3.7017882678
MESH:D015663 Osteoporosis, Postmenopausal Quercetin 4.0919495926
MESH:D010051 Ovarian Neoplasms Estradiol 10.9719401270
MESH:D010051 Ovarian Neoplasms Progesterone 10.9716525653 17393432
MESH:D010051 Ovarian Neoplasms Quercetin 10.9719005980
MESH:D010051 Ovarian Neoplasms Tretinoin 10.9716936753
MESH:D010146 Pain Tretinoin 2.8016870215
MESH:D010190 Pancreatic Neoplasms Diethylnitrosamine 8.3816540662
MESH:D010190 Pancreatic Neoplasms Quercetin 8.3816965848
MESH:D010190 Pancreatic Neoplasms Tretinoin 8.3815976015
MESH:D016584 Panic Disorder Ethinyl Estradiol 3.5611578682
MESH:D010382 Peliosis Hepatis Tetrachlorodibenzodioxin 4.1212520081
MESH:D010538 Peritonitis Zymosan 4.7518557954 18977430 15259001 11985352 15979727 17371808 18760300 19641140 14761945 17826846 19088179
MESH:D011014 Pneumonia Lipopolysaccharides 4.4211605937 12224865
MESH:D017119 Porphyria Cutanea Tarda Tetrachlorodibenzodioxin 3.4318163543
MESH:D011230 Precancerous Conditions Cyclosporine 14.6712371664
MESH:D011230 Precancerous Conditions Diethylnitrosamine 14.672563599
MESH:D011230 Precancerous Conditions Quercetin 14.6719056647
MESH:D011297 Prenatal Exposure Delayed Effects Tetrachlorodibenzodioxin 3.0611896295 11118676 11222880 11399792
MESH:D019048 Prostatic Intraepithelial Neoplasia Estradiol 3.7620887781
MESH:D011471 Prostatic Neoplasms Estradiol 2.6516740699
MESH:D011471 Prostatic Neoplasms Quercetin 2.6517292933 14715546
MESH:D011471 Prostatic Neoplasms Vitamin E 2.6515084515
MESH:D011507 Proteinuria Tretinoin 3.4816636307
MESH:D011537 Pruritus Ethinyl Estradiol 3.1815861022 16919318
MESH:D011565 Psoriasis Cyclosporine 2.1816882103
MESH:D011625 Pterygium Tretinoin 4.6616723453
MESH:D011657 Pulmonary Eosinophilia Ascorbic Acid 5.2014606601
MESH:D015427 Reperfusion Injury pirinixic acid 2.3219058328
MESH:D012130 Respiratory Hypersensitivity Lipopolysaccharides 3.6510835634
MESH:D015619 Respiratory System Abnormalities Tetrachlorodibenzodioxin 3.7118990726
MESH:D012174 Retinitis Pigmentosa Ascorbic Acid 3.2716849425
MESH:D012208 Rhabdomyosarcoma Tretinoin 3.9816283617 16116481
MESH:D012468 Salivary Gland Neoplasms Progesterone 2.8118045962
MESH:D012554 Schistosomiasis japonica Quercetin 5.4216862918
MESH:D012640 Seizures 2,6-dinitrotoluene 2.4518551238
MESH:D018805 Sepsis Zymosan 4.5411441115
MESH:D012871 Skin Diseases Ascorbic Acid 5.1018709164
MESH:D012871 Skin Diseases Vitamin E 5.1018709164
MESH:D012878 Skin Neoplasms Tetrachlorodibenzodioxin 5.3616192470
MESH:D012878 Skin Neoplasms Tretinoin 5.3616467112
MESH:D013088 Spermatocele Ethinyl Estradiol 3.8116709447
MESH:D013119 Spinal Cord Injuries Progesterone 4.1516503802 15862959
MESH:D013274 Stomach Neoplasms Diethylnitrosamine 2.3918456281
MESH:D013274 Stomach Neoplasms Tretinoin 2.3917261132
MESH:D013276 Stomach Ulcer Ascorbic Acid 3.7718726076
MESH:D020521 Stroke Ascorbic Acid 8.5416517955 16403987
MESH:D020521 Stroke Vitamin E 8.5416517955
MESH:D013921 Thrombocytopenia Lipopolysaccharides 4.0515821434
MESH:D019851 Thrombophilia Ethinyl Estradiol 3.5011994571
MESH:D013927 Thrombosis Ethinyl Estradiol 3.0415669648
MESH:D013959 Thyroid Diseases Tetrachlorodibenzodioxin 3.7712697716
MESH:D013964 Thyroid Neoplasms Diethylnitrosamine 6.847505956
MESH:D013964 Thyroid Neoplasms Tretinoin 6.8417045167 16026305
MESH:D013978 Tibial Fractures Estradiol 4.5619048282
MESH:D014062 Tongue Neoplasms Tretinoin 3.6716051514
MESH:D014376 Tuberculosis Tretinoin 3.1516040207
MESH:D001749 Urinary Bladder Neoplasms 2,6-dinitrotoluene 5.0316049721
MESH:D001749 Urinary Bladder Neoplasms Quercetin 5.0316720314
MESH:D014571 Urologic Neoplasms 2,6-dinitrotoluene 4.1910091137
MESH:D002583 Uterine Cervical Neoplasms Tretinoin 3.5616129372
MESH:D014594 Uterine Neoplasms Ethinyl Estradiol 3.1714692618
MESH:D014604 Uveal Neoplasms Tretinoin 4.4816752155
MESH:D014605 Uveitis Cyclosporine 11.551336536
MESH:D014605 Uveitis Zymosan 11.5511006244
MESH:D054079 Vascular Malformations Tetrachlorodibenzodioxin 4.4712125929
MESH:D020246 Venous Thrombosis Ethinyl Estradiol 3.4214671159 15869587
MESH:D014820 Vitiligo Tretinoin 3.9316761959
MESH:D019282 Wasting Syndrome Tetrachlorodibenzodioxin 4.1215886252
MESH:D015430 Weight Gain Dietary Fats 3.6216723640
MESH:D009396 Wilms Tumor Tretinoin 3.8516287080
MESH:D014985 Xerophthalmia Cyclosporine 4.3117120751
No data
Pharmacogenomics Knowledge Base Top
  • PharmGKB Accession:PA38370
    • No data
    Releated disease ID Related disease Name
    PA444818Lung Neoplasms
    PA444818Lung Neoplasms
    No data
    Drug Bank Top
    No data
    No data
    No data
    Drugbank ID Action Drug Name Description
    DB08231 - MYRISTIC ACID

    Simple Query:


      (e.g. CHD8)

    Syndromic Genes

    Non-syndromic Genes

    AutismKB Statistics

    • Studies: 1,036
    • Genes: 1,379
    • CNVs/SVs: 5,420
    • SNVs/Indels: 11,669
    • de novo Mutations: 5,669
    • Mosaics: 789
    • Linkage Regions: 172
    • Paper Collected: 6/30/2018
    • Last Update: 8/26/2018


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