AutismKB 2.0

Annotation Detail for MAPK9


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Basic Information Top
Gene Symbol:MAPK9 ( JNK-55,JNK2,JNK2A,JNK2ALPHA,JNK2B,JNK2BETA,PRKM9,SAPK,p54a,p54aSAPK )
Gene Full Name: mitogen-activated protein kinase 9
Band: 5q35.3
Quick LinksEntrez ID:5601; OMIM: 602896; Uniprot ID:MK09_HUMAN; ENSEMBL ID: ENSG00000050748; HGNC ID: 6886
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
No data
Pathway IDPathway Name
hsa04914Progesterone-mediated oocyte maturation
hsa04920Adipocytokine signaling pathway
hsa05160Hepatitis C
hsa04912GnRH signaling pathway
hsa04910Insulin signaling pathway
hsa04012ErbB signaling pathway
hsa04010MAPK signaling pathway
hsa04141Protein processing in endoplasmic reticulum
hsa05142Chagas disease
hsa05145Toxoplasmosis
hsa04310Wnt signaling pathway
hsa05120Epithelial cell signaling in Helicobacter pylori infection
hsa04620Toll-like receptor signaling pathway
hsa04621NOD-like receptor signaling pathway
hsa04622RIG-I-like receptor signaling pathway
hsa05131Shigellosis
hsa04722Neurotrophin signaling pathway
hsa05212Pancreatic cancer
hsa05210Colorectal cancer
hsa04510Focal adhesion
hsa05200Pathways in cancer
hsa04660T cell receptor signaling pathway
hsa04664Fc epsilon RI signaling pathway
hsa04930Type II diabetes mellitus
Pathway IDPathway Name
Signaling in Immune system
Pathway IDPathway Name
200031CD40/CD40L signaling
200184Downstream signaling in naive CD8+ T cells
200132Nephrin/Neph1 signaling in the kidney podocyte
200016Noncanonical Wnt signaling pathway
200082IL2-mediated signaling events
200067FAS (CD95) signaling pathway
200091FoxO family signaling
200090Rapid glucocorticoid signaling
200077Glucocorticoid receptor regulatory network
200076Role of Calcineurin-dependent NFAT signaling in lymphocytes
200119ErbB2/ErbB3 signaling events
200113ErbB1 downstream signaling
200116ATF-2 transcription factor network
200103p75(NTR)-mediated signaling
200192Signaling events mediated by focal adhesion kinase
200193Glypican 3 network
200190RAC1 signaling pathway
200191Regulation of retinoblastoma protein
200197IL12 signaling mediated by STAT4
200057CDC42 signaling events
Pathway IDPathway Name
P00003Alzheimer disease-amyloid secretase pathway
P00035Interferon-gamma signaling pathway
P00053T cell activation
P00046Oxidative stress response
P00018EGF receptor signaling pathway
P00052TGF-beta signaling pathway
P00020FAS signaling pathway
P00010B cell activation
P00054Toll receptor signaling pathway
P00029Huntington disease
P00049Parkinson disease
P00006Apoptosis signaling pathway
P00021FGF signaling pathway
P00034Integrin signalling pathway
P04393Ras Pathway
No data
Related Diseases/Disorders Top
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C085911 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one results in increased phosphorylation of and results in increased activity of MAPK9 proteinincreases activity|increases phosphorylation 16018989
C031278 2-chloroethyl ethyl sulfide 2-chloroethyl ethyl sulfide results in increased phosphorylation of MAPK9 proteinincreases phosphorylation 18675330
C090942 4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole 4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole inhibits the reaction [Doxorubicin results in increased phosphorylation of MAPK9 protein]decreases reaction|increases phosphorylation 15557793
C108123 4-amino-5-(4-methylphenyl)-7-(tert-butyl)pyrazolo(3,4-d)pyrimidine 4-amino-5-(4-methylphenyl)-7-(tert-butyl)pyrazolo(3,4-d)pyrimidine inhibits the reaction [Anisomycin results in increased phosphorylation of MAPK9 protein]decreases reaction|increases phosphorylation 15772366
C108123 4-amino-5-(4-methylphenyl)-7-(tert-butyl)pyrazolo(3,4-d)pyrimidine 4-amino-5-(4-methylphenyl)-7-(tert-butyl)pyrazolo(3,4-d)pyrimidine inhibits the reaction [deoxynivalenol results in increased phosphorylation of MAPK9 protein]decreases reaction|increases phosphorylation 15772366
C108123 4-amino-5-(4-methylphenyl)-7-(tert-butyl)pyrazolo(3,4-d)pyrimidine 4-amino-5-(4-methylphenyl)-7-(tert-butyl)pyrazolo(3,4-d)pyrimidine inhibits the reaction [Emetine results in increased phosphorylation of MAPK9 protein]decreases reaction|increases phosphorylation 15772366
C503119 5-((4-methylphenyl)methylene)-2-(phenylamino)-4(5H)-thiazolone 5-((4-methylphenyl)methylene)-2-(phenylamino)-4(5H)-thiazolone results in increased phosphorylation of MAPK9 proteinincreases phosphorylation 15831436
C503119 5-((4-methylphenyl)methylene)-2-(phenylamino)-4(5H)-thiazolone anthra(1,9-cd)pyrazol-6(2H)-one inhibits the reaction [5-((4-methylphenyl)methylene)-2-(phenylamino)-4(5H)-thiazolone results in increased phosphorylation of MAPK9 protein]decreases reaction|increases phosphorylation 15831436
D000079 Acetaldehyde Acetaldehyde results in increased phosphorylation of MAPK9 proteinincreases phosphorylation 19110045
D000079 Acetaldehyde Hesperidin inhibits the reaction [Acetaldehyde results in increased phosphorylation of MAPK9 protein]decreases reaction|increases phosphorylation 19110045
D000079 Acetaldehyde Acetaldehyde results in increased activity of MAPK9 proteinincreases activity 10733585
D000082 Acetaminophen Acetaminophen results in increased phosphorylation of and results in increased activity of MAPK9 proteinincreases activity|increases phosphorylation 19739265
18700144
D000082 Acetaminophen manumycin inhibits the reaction [Acetaminophen results in increased phosphorylation of and results in increased activity of MAPK9 protein]decreases reaction|increases activity|increases phosphorylation 19739265
D000082 Acetaminophen MAP3K5 protein promotes the reaction [Acetaminophen results in increased phosphorylation of and results in increased activity of MAPK9 protein]increases activity|increases phosphorylation|increases reaction 18700144
D000082 Acetaminophen MAPK9 protein results in increased susceptibility to Acetaminophenincreases response to substance 18700144
C412373 AG 1879 AG 1879 inhibits the reaction [deoxynivalenol results in increased phosphorylation of MAPK9 protein]decreases reaction|increases phosphorylation 15772366
C412373 AG 1879 AG 1879 inhibits the reaction [Hydrogen Peroxide results in increased activity of MAPK9 protein]decreases reaction|increases activity 15574683
D013196 Dihydrotestosterone APOE gene polymorphism affects the reaction [Dihydrotestosterone affects the phosphorylation of MAPK9 protein]affects phosphorylation|affects reaction 17395708
C010845 aluminum chloride aluminum chloride results in increased phosphorylation of and results in increased activity of MAPK9 proteinincreases activity|increases phosphorylation 12865155
C010845 aluminum chloride CEP-11004 inhibits the reaction [aluminum chloride results in increased phosphorylation of and results in increased activity of MAPK9 protein]decreases reaction|increases activity|increases phosphorylation 12865155
D000643 Ammonium Chloride Ammonium Chloride affects the expression of MAPK9 mRNAaffects expression 16483693
C023650 aniline aniline results in increased phosphorylation of MAPK9 proteinincreases phosphorylation 16169568
18420242
D000841 Anisomycin 4-amino-5-(4-methylphenyl)-7-(tert-butyl)pyrazolo(3,4-d)pyrimidine inhibits the reaction [Anisomycin results in increased phosphorylation of MAPK9 protein]decreases reaction|increases phosphorylation 15772366
D000841 Anisomycin Anisomycin results in increased phosphorylation of MAPK9 proteinincreases phosphorylation 16038797
15772366
C432165 anthra(1,9-cd)pyrazol-6(2H)-one anthra(1,9-cd)pyrazol-6(2H)-one inhibits the reaction [5-((4-methylphenyl)methylene)-2-(phenylamino)-4(5H)-thiazolone results in increased phosphorylation of MAPK9 protein]decreases reaction|increases phosphorylation 15831436
C432165 anthra(1,9-cd)pyrazol-6(2H)-one anthra(1,9-cd)pyrazol-6(2H)-one inhibits the reaction [silybin results in increased phosphorylation of MAPK9 protein]decreases reaction|increases phosphorylation 16777994
C432165 anthra(1,9-cd)pyrazol-6(2H)-one anthra(1,9-cd)pyrazol-6(2H)-one inhibits the reaction [Sodium Selenite results in increased phosphorylation of and results in increased activity of MAPK9 protein]decreases reaction|increases activity|increases phosphorylation 18728404
C432165 anthra(1,9-cd)pyrazol-6(2H)-one anthra(1,9-cd)pyrazol-6(2H)-one inhibits the reaction [TNF protein results in increased phosphorylation of MAPK9 protein]decreases reaction|increases phosphorylation 15322261
C432165 anthra(1,9-cd)pyrazol-6(2H)-one anthra(1,9-cd)pyrazol-6(2H)-one inhibits the reaction [Calcimycin results in increased phosphorylation of and results in increased activity of MAPK9 protein]decreases reaction|increases activity|increases phosphorylation 16000378
C432165 anthra(1,9-cd)pyrazol-6(2H)-one anthra(1,9-cd)pyrazol-6(2H)-one results in decreased phosphorylation of and results in decreased activity of MAPK9 proteindecreases activity|decreases phosphorylation 16000378
C432165 anthra(1,9-cd)pyrazol-6(2H)-one anthra(1,9-cd)pyrazol-6(2H)-one inhibits the reaction [Paraquat results in increased phosphorylation of MAPK9 protein]decreases reaction|increases phosphorylation 16687388
C432165 anthra(1,9-cd)pyrazol-6(2H)-one anthra(1,9-cd)pyrazol-6(2H)-one inhibits the reaction [pentaacetyl geniposide results in increased phosphorylation of MAPK9 protein]decreases reaction|increases phosphorylation 17651887
D001149 Arsenates [Arsenates co-treated with chromium hexavalent ion] results in increased expression of MAPK9 proteinaffects cotreatment|increases expression 19895865
D001149 Arsenates [Arsenates co-treated with chromium hexavalent ion] results in increased phosphorylation of MAPK9 proteinaffects cotreatment|increases phosphorylation 19895865
D001151 Arsenic Arsenic results in increased phosphorylation of and results in increased activity of MAPK9 proteinincreases activity|increases phosphorylation 14633691
C006632 arsenic trioxide [IL24 protein co-treated with arsenic trioxide] results in increased phosphorylation of MAPK9 proteinaffects cotreatment|increases phosphorylation 15580305
C006632 arsenic trioxide indole-5-carboxamide promotes the reaction [arsenic trioxide results in increased phosphorylation of and results in increased activity of MAPK9 protein]increases activity|increases phosphorylation|increases reaction 16818652
C006632 arsenic trioxide SB 203580 promotes the reaction [arsenic trioxide results in increased phosphorylation of and results in increased activity of MAPK9 protein]increases activity|increases phosphorylation|increases reaction 16818652
C006632 arsenic trioxide SCIO-469 promotes the reaction [arsenic trioxide results in increased phosphorylation of and results in increased activity of MAPK9 protein]increases activity|increases phosphorylation|increases reaction 16818652
C006632 arsenic trioxide arsenic trioxide results in increased phosphorylation of MAPK9 proteinincreases phosphorylation 15688020
C006632 arsenic trioxide MAPK9 protein results in increased susceptibility to arsenic trioxideincreases response to substance 16818652
C015001 arsenite arsenite results in increased phosphorylation of MAPK9 proteinincreases phosphorylation 19808956
C015001 arsenite MAP3K8 protein affects the reaction [arsenite results in increased phosphorylation of MAPK9 protein]affects reaction|increases phosphorylation 19808956
D001554 Benzene TP53 protein inhibits the reaction [Benzene results in increased expression of MAPK9]decreases reaction|increases expression 15935813
D001564 Benzo(a)pyrene Benzo(a)pyrene results in increased phosphorylation of MAPK9 proteinincreases phosphorylation 18321868
D001564 Benzo(a)pyrene Curcumin inhibits the reaction [Benzo(a)pyrene results in increased phosphorylation of MAPK9 protein]decreases reaction|increases phosphorylation 18321868
D015123 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in increased phosphorylation of MAPK9 proteinincreases phosphorylation 20382639
C006780 bisphenol A bisphenol A results in increased phosphorylation of MAPK9 proteinincreases phosphorylation 20096755
D002104 Cadmium Cadmium results in increased phosphorylation of and results in increased activity of MAPK9 proteinincreases activity|increases phosphorylation 16728380
D002104 Cadmium [MT1 protein co-treated with MT2 protein] inhibits the reaction [Cadmium results in increased phosphorylation of MAPK9 protein]affects cotreatment|decreases reaction|increases phosphorylation 16568437
D002104 Cadmium Silymarin inhibits the reaction [Cadmium results in increased phosphorylation of and results in increased activity of MAPK9 protein]decreases reaction|increases activity|increases phosphorylation 16728380
D002104 Cadmium Cadmium results in increased phosphorylation of and results in increased activity of MAPK9 proteinincreases activity|increases phosphorylation 16568437
D002104 Cadmium MAPK9 protein affects the susceptibility to Cadmiumaffects response to substance 16516943
D019256 Cadmium Chloride [sodium arsenite co-treated with Cadmium Chloride co-treated with chromium oxide co-treated with chromous chloride co-treated with lead acetate] results in decreased expression of MAPK9 mRNAaffects cotreatment|decreases expression 12634122
D019256 Cadmium Chloride Cadmium Chloride results in increased phosphorylation of and results in increased activity of MAPK9 proteinincreases activity|increases phosphorylation 16728380
D019256 Cadmium Chloride Silymarin inhibits the reaction [Cadmium Chloride results in increased phosphorylation of and results in increased activity of MAPK9 protein]decreases reaction|increases activity|increases phosphorylation 16728380
C472707 caffeoylquinic acid caffeoylquinic acid analog results in increased phosphorylation of MAPK9 proteinincreases phosphorylation 19647727
D000001 Calcimycin anthra(1,9-cd)pyrazol-6(2H)-one inhibits the reaction [Calcimycin results in increased phosphorylation of and results in increased activity of MAPK9 protein]decreases reaction|increases activity|increases phosphorylation 16000378
D000001 Calcimycin Calcimycin results in increased phosphorylation of and results in increased activity of MAPK9 proteinincreases activity|increases phosphorylation 16000378
D002166 Camptothecin Camptothecin results in increased phosphorylation of MAPK9 proteinincreases phosphorylation 15585644
D002251 Carbon Tetrachloride Carbon Tetrachloride affects the expression of MAPK9 mRNAaffects expression 16239168
D002251 Carbon Tetrachloride Carbon Tetrachloride results in increased expression of MAPK9 proteinincreases expression 18081878
C469298 CEP-11004 CEP-11004 inhibits the reaction [aluminum chloride results in increased phosphorylation of and results in increased activity of MAPK9 protein]decreases reaction|increases activity|increases phosphorylation 12865155
C074702 chromium hexavalent ion chromium hexavalent ion results in increased phosphorylation of MAPK9 proteinincreases phosphorylation 17045426
C074702 chromium hexavalent ion [Arsenates co-treated with chromium hexavalent ion] results in increased expression of MAPK9 proteinaffects cotreatment|increases expression 19895865
C074702 chromium hexavalent ion [Arsenates co-treated with chromium hexavalent ion] results in increased phosphorylation of MAPK9 proteinaffects cotreatment|increases phosphorylation 19895865
C074702 chromium hexavalent ion chromium hexavalent ion results in increased expression of MAPK9 proteinincreases expression 19895865
C074702 chromium hexavalent ion chromium hexavalent ion results in increased phosphorylation of MAPK9 proteinincreases phosphorylation 19895865
C023600 chromium oxide [sodium arsenite co-treated with Cadmium Chloride co-treated with chromium oxide co-treated with chromous chloride co-treated with lead acetate] results in decreased expression of MAPK9 mRNAaffects cotreatment|decreases expression 12634122
C017133 chromous chloride [sodium arsenite co-treated with Cadmium Chloride co-treated with chromium oxide co-treated with chromous chloride co-treated with lead acetate] results in decreased expression of MAPK9 mRNAaffects cotreatment|decreases expression 12634122
D002995 Clofibric Acid [Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of MAPK9 mRNAaffects cotreatment|affects expression 17602206
D003024 Clozapine Clozapine affects the expression of MAPK9 mRNAaffects expression 15860345
D003078 Colchicine TP53 protein affects the reaction [Colchicine results in increased phosphorylation of MAPK9 protein]affects reaction|increases phosphorylation 12221076
D003474 Curcumin Curcumin results in increased phosphorylation of MAPK9 proteinincreases phosphorylation 18316600
D003474 Curcumin Curcumin inhibits the reaction [Benzo(a)pyrene results in increased phosphorylation of MAPK9 protein]decreases reaction|increases phosphorylation 18321868
D003474 Curcumin Curcumin results in decreased phosphorylation of and results in decreased activity of MAPK9 proteindecreases activity|decreases phosphorylation 17372590
D003474 Curcumin Curcumin results in decreased phosphorylation of MAPK9 proteindecreases phosphorylation 18332871
C057862 cyanoginosin LR cyanoginosin LR results in increased expression of MAPK9 mRNAincreases expression 17654400
D016572 Cyclosporine Cyclosporine results in increased expression of MAPK9 mRNAincreases expression 20106945
D003634 DDT DDT results in decreased phosphorylation of MAPK9 proteindecreases phosphorylation 14604893
D003676 Deferoxamine Deferoxamine results in increased phosphorylation of MAPK9 proteinincreases phosphorylation 20368581
C007262 deoxynivalenol deoxynivalenol results in increased phosphorylation of and results in increased activity of MAPK9 proteinincreases activity|increases phosphorylation 18485432
19360757
C007262 deoxynivalenol 4-amino-5-(4-methylphenyl)-7-(tert-butyl)pyrazolo(3,4-d)pyrimidine inhibits the reaction [deoxynivalenol results in increased phosphorylation of MAPK9 protein]decreases reaction|increases phosphorylation 15772366
C007262 deoxynivalenol AG 1879 inhibits the reaction [deoxynivalenol results in increased phosphorylation of MAPK9 protein]decreases reaction|increases phosphorylation 15772366
C007262 deoxynivalenol deoxynivalenol promotes the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK9 protein]increases phosphorylation|increases reaction 14644621
C007262 deoxynivalenol deoxynivalenol results in decreased expression of MAPK9 mRNAdecreases expression 15371230
C007262 deoxynivalenol deoxynivalenol results in increased phosphorylation of MAPK9 proteinincreases phosphorylation 14690764
12604842
18502741
15570035
16424113
12377986
15772366
14644621
C007262 deoxynivalenol Docosahexaenoic Acids inhibits the reaction [deoxynivalenol results in increased phosphorylation of MAPK9 protein]decreases reaction|increases phosphorylation 14690764
15570035
16424113
C007262 deoxynivalenol Eicosapentaenoic Acid inhibits the reaction [deoxynivalenol results in increased phosphorylation of MAPK9 protein]decreases reaction|increases phosphorylation 14690764
C007262 deoxynivalenol Fish Oils inhibits the reaction [deoxynivalenol results in increased phosphorylation of MAPK9 protein]decreases reaction|increases phosphorylation 14690764
D004052 Diethylnitrosamine [Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of MAPK9 mRNAaffects cotreatment|affects expression 17602206
D004128 Dimethylnitrosamine Dimethylnitrosamine results in increased phosphorylation of and results in increased activity of MAPK9 proteinincreases activity|increases phosphorylation 12971962
D004178 Diquat PROP1 protein affects the reaction [Diquat affects the phosphorylation of MAPK9 protein]affects phosphorylation|affects reaction 20826540
D004280 Dobutamine [Dobutamine co-treated with ICI 118551] results in increased activity of MAPK9 proteinaffects cotreatment|increases activity 19719783
D004281 Docosahexaenoic Acids Docosahexaenoic Acids inhibits the reaction [deoxynivalenol results in increased phosphorylation of MAPK9 protein]decreases reaction|increases phosphorylation 16424113
14690764
15570035
D004317 Doxorubicin 4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole inhibits the reaction [Doxorubicin results in increased phosphorylation of MAPK9 protein]decreases reaction|increases phosphorylation 15557793
D004317 Doxorubicin Doxorubicin results in increased phosphorylation of and results in increased activity of MAPK9 proteinincreases activity|increases phosphorylation 15494689
D004317 Doxorubicin Doxorubicin results in increased phosphorylation of MAPK9 proteinincreases phosphorylation 15557793
15585644
D004317 Doxorubicin pyrrolidine dithiocarbamic acid inhibits the reaction [Doxorubicin results in increased phosphorylation of MAPK9 protein]decreases reaction|increases phosphorylation 15557793
D004317 Doxorubicin RBL2 protein inhibits the reaction [Doxorubicin results in increased phosphorylation of MAPK9 protein]decreases reaction|increases phosphorylation 15585644
D004317 Doxorubicin Doxorubicin results in increased phosphorylation of and results in increased activity of MAPK9 proteinincreases activity|increases phosphorylation 16687611
D004317 Doxorubicin Doxorubicin results in increased phosphorylation of MAPK9 proteinincreases phosphorylation 17384285
16213474
D004317 Doxorubicin pifithrin inhibits the reaction [Doxorubicin results in increased phosphorylation of and results in increased activity of MAPK9 protein]decreases reaction|increases activity|increases phosphorylation 16687611
C060327 dracorhodin dracorhodin analog results in increased phosphorylation of MAPK9 proteinincreases phosphorylation 15684474
D004365 Drugs, Chinese Herbal Drugs, Chinese Herbal results in increased phosphorylation of MAPK9 proteinincreases phosphorylation 15894585
D004365 Drugs, Chinese Herbal Drugs, Chinese Herbal results in increased phosphorylation of MAPK9 proteinincreases phosphorylation 19647727
C479799 (E)-4-((2-N-(4-methoxybenzenesulfonyl)amino)stilbazole)1-oxide (E)-4-((2-N-(4-methoxybenzenesulfonyl)amino)stilbazole)1-oxide results in decreased expression of MAPK9 mRNAdecreases expression 15528975
D015118 Eicosapentaenoic Acid Eicosapentaenoic Acid inhibits the reaction [deoxynivalenol results in increased phosphorylation of MAPK9 protein]decreases reaction|increases phosphorylation 14690764
D004640 Emetine 4-amino-5-(4-methylphenyl)-7-(tert-butyl)pyrazolo(3,4-d)pyrimidine inhibits the reaction [Emetine results in increased phosphorylation of MAPK9 protein]decreases reaction|increases phosphorylation 15772366
D004640 Emetine Emetine results in increased phosphorylation of MAPK9 proteinincreases phosphorylation 15772366
C045651 epigallocatechin gallate epigallocatechin gallate inhibits the reaction [[Paclitaxel co-treated with F2 protein] results in increased phosphorylation of MAPK9 protein]affects cotreatment|decreases reaction|increases phosphorylation 19944065
C007628 esculetin [esculetin co-treated with Paclitaxel] results in increased expression of MAPK9 proteinaffects cotreatment|increases expression 16051289
C007628 esculetin esculetin results in increased expression of MAPK9 proteinincreases expression 16051289
D005395 Fish Oils Fish Oils inhibits the reaction [deoxynivalenol results in increased phosphorylation of MAPK9 protein]decreases reaction|increases phosphorylation 14690764
D005947 Glucose Glucose results in increased phosphorylation of MAPK9 proteinincreases phosphorylation 19861503
C078131 GM 6001 GM 6001 inhibits the reaction [Hydrogen Peroxide results in increased activity of MAPK9 protein]decreases reaction|increases activity 15574683
D006220 Haloperidol Haloperidol affects the expression of MAPK9 mRNAaffects expression 15860345
D006569 Hesperidin Hesperidin inhibits the reaction [Acetaldehyde results in increased phosphorylation of MAPK9 protein]decreases reaction|increases phosphorylation 19110045
D017313 Fenretinide [IL24 protein co-treated with Fenretinide] results in increased phosphorylation of MAPK9 proteinaffects cotreatment|increases phosphorylation 15580305
D006861 Hydrogen Peroxide Hydrogen Peroxide results in decreased expression of MAPK9 mRNAdecreases expression 12419474
D006861 Hydrogen Peroxide Hydrogen Peroxide results in increased phosphorylation of MAPK9 proteinincreases phosphorylation 15795422
D006861 Hydrogen Peroxide Quercetin inhibits the reaction [Hydrogen Peroxide results in increased phosphorylation of MAPK9 protein]decreases reaction|increases phosphorylation 15795422
D006861 Hydrogen Peroxide Hydrogen Peroxide results in increased activity of MAPK9 proteinincreases activity 11181820
D006861 Hydrogen Peroxide AG 1879 inhibits the reaction [Hydrogen Peroxide results in increased activity of MAPK9 protein]decreases reaction|increases activity 15574683
D006861 Hydrogen Peroxide GM 6001 inhibits the reaction [Hydrogen Peroxide results in increased activity of MAPK9 protein]decreases reaction|increases activity 15574683
D006861 Hydrogen Peroxide Hydrogen Peroxide results in increased activity of MAPK9 proteinincreases activity 15574683
C026777 ICI 118551 [Dobutamine co-treated with ICI 118551] results in increased activity of MAPK9 proteinaffects cotreatment|increases activity 19719783
C514526 indole-5-carboxamide indole-5-carboxamide promotes the reaction [arsenic trioxide results in increased phosphorylation of and results in increased activity of MAPK9 protein]increases activity|increases phosphorylation|increases reaction 16818652
C008261 lead acetate [sodium arsenite co-treated with Cadmium Chloride co-treated with chromium oxide co-treated with chromous chloride co-treated with lead acetate] results in decreased expression of MAPK9 mRNAaffects cotreatment|decreases expression 12634122
D008070 Lipopolysaccharides deoxynivalenol promotes the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK9 protein]increases phosphorylation|increases reaction 14644621
D008070 Lipopolysaccharides GSTP1 protein inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK9 protein]decreases reaction|increases phosphorylation 16023107
D008070 Lipopolysaccharides Lipopolysaccharides results in increased phosphorylation of MAPK9 proteinincreases phosphorylation 16023107
14644621
C005095 malachite green malachite green results in decreased phosphorylation of MAPK9 proteindecreases phosphorylation 16675904
15566957
D008345 Manganese Manganese results in increased phosphorylation of MAPK9 proteinincreases phosphorylation 17045426
C013592 mangiferin mangiferin results in decreased expression of MAPK9 mRNAdecreases expression 15135318
C054474 manumycin manumycin inhibits the reaction [Acetaminophen results in increased phosphorylation of and results in increased activity of MAPK9 protein]decreases reaction|increases activity|increases phosphorylation 19739265
D008687 Metformin Metformin inhibits the reaction [IL1B protein results in increased phosphorylation of MAPK9 protein]decreases reaction|increases phosphorylation 16385087
D008769 Methylnitronitrosoguanidine Methylnitronitrosoguanidine results in increased expression of MAPK9 mRNAincreases expression 12634122
D015655 1-Methyl-4-phenylpyridinium 1-Methyl-4-phenylpyridinium results in increased activity of MAPK9 proteinincreases activity 11181820
C008493 methylselenic acid methylselenic acid results in decreased expression of MAPK9 mRNAdecreases expression 11830524
D009151 Mustard Gas Mustard Gas results in increased phosphorylation of MAPK9 proteinincreases phosphorylation 18200059
C040015 myricetin myricetin inhibits the reaction [EGF protein results in increased phosphorylation of MAPK9 protein]decreases reaction|increases phosphorylation 17693661
C040015 myricetin myricetin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK9 protein]decreases reaction|increases phosphorylation 17693661
D015739 Nocodazole TP53 protein affects the reaction [Nocodazole results in increased phosphorylation of MAPK9 protein]affects reaction|increases phosphorylation 12221076
D009638 Norepinephrine MAPK10 protein affects the reaction [MAPK9 protein affects the susceptibility to Norepinephrine]affects reaction|affects response to substance 16949803
D009638 Norepinephrine MAPK9 protein affects the susceptibility to Norepinephrineaffects response to substance 16949803
D010100 Oxygen MAPK9 protein affects the reaction [Oxygen deficiency results in increased expression of BACE1 protein]affects reaction|increases expression 19196431
D010100 Oxygen Oxygen deficiency results in increased phosphorylation of MAPK9 proteinincreases phosphorylation 19196431
D010126 Ozone Ozone results in increased phosphorylation of MAPK9 proteinincreases phosphorylation 19536146
D017239 Paclitaxel epigallocatechin gallate inhibits the reaction [[Paclitaxel co-treated with F2 protein] results in increased phosphorylation of MAPK9 protein]affects cotreatment|decreases reaction|increases phosphorylation 19944065
D017239 Paclitaxel [esculetin co-treated with Paclitaxel] results in increased expression of MAPK9 proteinaffects cotreatment|increases expression 16051289
D017239 Paclitaxel [Paclitaxel co-treated with F2 protein] results in increased phosphorylation of MAPK9 proteinaffects cotreatment|increases phosphorylation 19944065
D017239 Paclitaxel Paclitaxel results in increased expression of MAPK9 proteinincreases expression 16051289
D017239 Paclitaxel Paclitaxel analog results in increased expression of MAPK9 mRNAincreases expression 15585946
D010269 Paraquat Paraquat results in increased phosphorylation of and results in increased activity of MAPK9 proteinincreases activity|increases phosphorylation 17018646
D010269 Paraquat anthra(1,9-cd)pyrazol-6(2H)-one inhibits the reaction [Paraquat results in increased phosphorylation of MAPK9 protein]decreases reaction|increases phosphorylation 16687388
D010269 Paraquat Paraquat results in increased phosphorylation of MAPK9 proteinincreases phosphorylation 16687388
C002669 parthenolide parthenolide results in increased expression of MAPK9 mRNAincreases expression 16921510
C074968 pentaacetyl geniposide anthra(1,9-cd)pyrazol-6(2H)-one inhibits the reaction [pentaacetyl geniposide results in increased phosphorylation of MAPK9 protein]decreases reaction|increases phosphorylation 17651887
C074968 pentaacetyl geniposide pentaacetyl geniposide results in increased phosphorylation of MAPK9 proteinincreases phosphorylation 17651887
D010656 Phenylephrine MAPK10 protein affects the reaction [MAPK9 protein affects the susceptibility to Phenylephrine]affects reaction|affects response to substance 16949803
D010656 Phenylephrine MAPK9 protein affects the susceptibility to Phenylephrineaffects response to substance 16949803
D010656 Phenylephrine Phenylephrine results in increased phosphorylation of MAPK9 proteinincreases phosphorylation 10727428
C121565 pifithrin pifithrin inhibits the reaction [silybin results in increased phosphorylation of MAPK9 protein]decreases reaction|increases phosphorylation 16777994
C121565 pifithrin pifithrin inhibits the reaction [Doxorubicin results in increased phosphorylation of and results in increased activity of MAPK9 protein]decreases reaction|increases activity|increases phosphorylation 16687611
D011134 Polysaccharides Polysaccharides results in increased phosphorylation of MAPK9 proteinincreases phosphorylation 15894585
D011189 Potassium Chloride MAPK10 protein affects the reaction [MAPK9 protein affects the susceptibility to Potassium Chloride]affects reaction|affects response to substance 16949803
D011374 Progesterone Progesterone results in increased expression of MAPK9 mRNAincreases expression 17170212
C020972 pyrrolidine dithiocarbamic acid pyrrolidine dithiocarbamic acid inhibits the reaction [Doxorubicin results in increased phosphorylation of MAPK9 protein]decreases reaction|increases phosphorylation 15557793
D011794 Quercetin Quercetin inhibits the reaction [Hydrogen Peroxide results in increased phosphorylation of MAPK9 protein]decreases reaction|increases phosphorylation 15795422
D012402 Rotenone Rotenone results in increased activity of MAPK9 proteinincreases activity 11181820
C093642 SB 203580 SB 203580 promotes the reaction [arsenic trioxide results in increased phosphorylation of and results in increased activity of MAPK9 protein]increases activity|increases phosphorylation|increases reaction 16818652
C093642 SB 203580 [Selenium co-treated with SB 203580] results in decreased expression of MAPK9 proteinaffects cotreatment|decreases expression 18583539
C499748 SCIO-469 SCIO-469 promotes the reaction [arsenic trioxide results in increased phosphorylation of and results in increased activity of MAPK9 protein]increases activity|increases phosphorylation|increases reaction 16818652
D012643 Selenium [Selenium co-treated with SB 203580] results in decreased expression of MAPK9 proteinaffects cotreatment|decreases expression 18583539
D012643 Selenium Selenium results in decreased expression of MAPK9 protein modified formdecreases expression 18583539
D017640 Silicates Silicates results in increased phosphorylation of MAPK9 proteinincreases phosphorylation 11280724
C440975 silybin anthra(1,9-cd)pyrazol-6(2H)-one inhibits the reaction [silybin results in increased phosphorylation of MAPK9 protein]decreases reaction|increases phosphorylation 16777994
C440975 silybin pifithrin inhibits the reaction [silybin results in increased phosphorylation of MAPK9 protein]decreases reaction|increases phosphorylation 16777994
C440975 silybin silybin results in increased phosphorylation of MAPK9 proteinincreases phosphorylation 16777994
D012838 Silymarin Silymarin inhibits the reaction [Cadmium Chloride results in increased phosphorylation of and results in increased activity of MAPK9 protein]decreases reaction|increases activity|increases phosphorylation 16728380
D012838 Silymarin Silymarin inhibits the reaction [Cadmium results in increased phosphorylation of and results in increased activity of MAPK9 protein]decreases reaction|increases activity|increases phosphorylation 16728380
C017947 sodium arsenite [sodium arsenite co-treated with Cadmium Chloride co-treated with chromium oxide co-treated with chromous chloride co-treated with lead acetate] results in decreased expression of MAPK9 mRNAaffects cotreatment|decreases expression 12634122
C017947 sodium arsenite sodium arsenite results in increased phosphorylation of MAPK9 proteinincreases phosphorylation 12482858
19154403
C017947 sodium arsenite MAPK9 protein promotes the reaction [sodium arsenite results in increased activity of CASP3 protein]increases activity|increases reaction 16973625
C017947 sodium arsenite MAPK9 protein promotes the reaction [sodium arsenite results in increased cleavage of PARP1 protein]increases cleavage|increases reaction 16973625
C017947 sodium arsenite MAPK9 protein promotes the reaction [sodium arsenite results in increased expression of GADD45A mRNA]increases expression|increases reaction 16973625
C017947 sodium arsenite MAPK9 protein promotes the reaction [sodium arsenite results in increased expression of GADD45A protein]increases expression|increases reaction 16973625
C017947 sodium arsenite MAPK9 protein promotes the reaction [sodium arsenite results in increased phosphorylation of and results in increased activity of JUN protein]increases activity|increases phosphorylation|increases reaction 16973625
C017947 sodium arsenite sodium arsenite results in increased phosphorylation of MAPK9 proteinincreases phosphorylation 18996350
16973625
C017947 sodium arsenite sodium arsenite results in increased phosphorylation of MAPK9 proteinincreases phosphorylation 11408547
D018038 Sodium Selenite anthra(1,9-cd)pyrazol-6(2H)-one inhibits the reaction [Sodium Selenite results in increased phosphorylation of and results in increased activity of MAPK9 protein]decreases reaction|increases activity|increases phosphorylation 18728404
D018038 Sodium Selenite Sodium Selenite results in increased expression of MAPK9 proteinincreases expression 18728404
D018038 Sodium Selenite Sodium Selenite results in increased phosphorylation of and results in increased activity of MAPK9 proteinincreases activity|increases phosphorylation 18728404
D018038 Sodium Selenite Sodium Selenite affects the expression of MAPK9affects expression 18209489
D012460 Sulfasalazine Sulfasalazine results in increased phosphorylation of MAPK9 proteinincreases phosphorylation 15633128
C016766 sulforafan sulforafan results in increased phosphorylation of MAPK9 proteinincreases phosphorylation 16033772
D013629 Tamoxifen Tamoxifen affects the expression of MAPK9 mRNAaffects expression 14699072
C020806 tetrabromobisphenol A tetrabromobisphenol A results in increased phosphorylation of MAPK9 proteinincreases phosphorylation 16198432
D013755 Tetradecanoylphorbol Acetate Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK9 proteinincreases phosphorylation 16838270
D013755 Tetradecanoylphorbol Acetate myricetin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK9 protein]decreases reaction|increases phosphorylation 17693661
D013755 Tetradecanoylphorbol Acetate Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK9 proteinincreases phosphorylation 17693661
D014212 Tretinoin Tretinoin results in decreased phosphorylation of and results in decreased activity of MAPK9 proteindecreases activity|decreases phosphorylation 16043492
D014260 Triclosan Triclosan inhibits the reaction [TNF protein results in increased phosphorylation of and results in increased activity of MAPK9 protein]decreases reaction|increases activity|increases phosphorylation 19874453
D014747 Vinblastine TP53 protein affects the reaction [Vinblastine results in increased phosphorylation of MAPK9 protein]affects reaction|increases phosphorylation 12221076
C025643 vinclozolin vinclozolin affects the expression of MAPK9 mRNAaffects expression 19015723
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000008 Abdominal Neoplasms Tamoxifen 3.6314745880
MESH:D000038 Abscess Drugs, Chinese Herbal 5.3915043669
MESH:D000138 Acidosis Ammonium Chloride 2.6618287403
MESH:D058186 Acute Kidney Injury pifithrin 4.0717670903
MESH:D055371 Acute Lung Injury Lipopolysaccharides 6.7711850527 18653653
MESH:D055371 Acute Lung Injury Oxygen 6.7716759491
MESH:D000230 Adenocarcinoma 5-((4-methylphenyl)methylene)-2-(phenylamino)-4(5H)-thiazolone 15.4415831436
MESH:D000230 Adenocarcinoma arsenic trioxide 15.4411798837 19825857
MESH:D000230 Adenocarcinoma Benzo(a)pyrene 15.4420464547 20127859
MESH:D000230 Adenocarcinoma Dimethylnitrosamine 15.4416033868
MESH:D000230 Adenocarcinoma Doxorubicin 15.4417418594
MESH:D000230 Adenocarcinoma dracorhodin 15.4415215653
MESH:D000230 Adenocarcinoma Fenretinide 15.4410697514
MESH:D000236 Adenoma Benzo(a)pyrene 7.686695378
MESH:D000236 Adenoma Diethylnitrosamine 7.6810737359 6695378
MESH:D000236 Adenoma Dimethylnitrosamine 7.6819555203
MESH:D018248 Adenoma, Liver Cell DDT 7.7512597452
MESH:D018248 Adenoma, Liver Cell Diethylnitrosamine 7.7517162532 18056438 19052882 19061943 17620307 16434500
MESH:D011125 Adenomatous Polyposis Coli sulforafan 4.4617942926
MESH:D000310 Adrenal Gland Neoplasms sodium arsenite 3.7815276417
MESH:D018246 Adrenocortical Adenoma Arsenic 10.7317306315
MESH:D018246 Adrenocortical Adenoma sodium arsenite 10.7316712894 17306315
MESH:D000380 Agranulocytosis Clozapine 4.1712649775 16160616 14617031
MESH:D000382 Agricultural Workers' Diseases DDT 6.1412584743 16487989
MESH:D000382 Agricultural Workers' Diseases Paraquat 6.1411874814
MESH:D000419 Albuminuria Doxorubicin 3.6821441931
MESH:D019973 Alcohol-Related Disorders Curcumin 4.1617887948
MESH:D000505 Alopecia Tretinoin 2.8615955085
MESH:D000544 Alzheimer Disease Curcumin 3.3715590663
MESH:D000544 Alzheimer Disease Ozone 3.3715513908
MESH:D000707 Anaphylaxis mangiferin 4.5814669257 16536907
MESH:D000740 Anemia Drugs, Chinese Herbal 3.8715504547 17963324
MESH:D000741 Anemia, Aplastic Benzene 3.6317661222 14761424 11369114
MESH:D000743 Anemia, Hemolytic Quercetin 3.4117084956
MESH:D000756 Anemia, Sideroblastic Manganese 4.0316910769
MESH:D000787 Angina Pectoris Drugs, Chinese Herbal 4.5011477813
MESH:D000799 Angioedema Acetaminophen 2.9210982225
MESH:D000860 Anoxia Oxygen 4.1520872349
MESH:D001004 Anus Diseases Drugs, Chinese Herbal 5.0415043669
MESH:D001008 Anxiety Disorders vinclozolin 2.8919015723
MESH:D017544 Aortic Aneurysm, Abdominal Benzo(a)pyrene 3.1919183758
MESH:D001145 Arrhythmias, Cardiac Phenylephrine 3.3217460149
MESH:D020261 Arsenic Poisoning Arsenic 2.5216835338 12569548 16251483 18414634
MESH:D001169 Arthritis, Experimental Tretinoin 2.4516412693
MESH:D015210 Arthritis, Gouty Drugs, Chinese Herbal 4.8419655406
MESH:D001172 Arthritis, Rheumatoid Curcumin 7.8816807698
MESH:D001172 Arthritis, Rheumatoid Ozone 7.8815570426
MESH:D001172 Arthritis, Rheumatoid Sulfasalazine 7.889133974
MESH:D001172 Arthritis, Rheumatoid Tretinoin 7.8816292516
MESH:D053627 Asthenozoospermia Sulfasalazine 5.3710689203
MESH:D001249 Asthma Acetaldehyde 10.709600491
MESH:D001249 Asthma epigallocatechin gallate 10.7016516891
MESH:D001249 Asthma Mustard Gas 10.7010378619
MESH:D001249 Asthma Ozone 10.7017854713 16373670
MESH:D001249 Asthma Tretinoin 10.7016456186
MESH:D001260 Ataxia Telangiectasia Quercetin 4.0715336622
MESH:D050197 Atherosclerosis Arsenic 14.0412928151 19371607
MESH:D050197 Atherosclerosis Cadmium 14.0415687053
MESH:D050197 Atherosclerosis Curcumin 14.0418704882
MESH:D050197 Atherosclerosis mangiferin 14.0418450471
MESH:D050197 Atherosclerosis Oxygen 14.0416391483
MESH:D001321 Autistic Disorder Acetaminophen 2.2818445737
MESH:D001321 Autistic Disorder Docosahexaenoic Acids 2.2818582451
MESH:D001321 Autistic Disorder Haloperidol 2.2818080171 19368416
MESH:D001321 Autistic Disorder Norepinephrine 2.288570775
MESH:D001327 Autoimmune Diseases Curcumin 18.6419761891
MESH:D001327 Autoimmune Diseases epigallocatechin gallate 18.6419761891
MESH:D001327 Autoimmune Diseases Quercetin 18.6419761891
MESH:D001327 Autoimmune Diseases sulforafan 18.6419761891
MESH:D001471 Barrett Esophagus Tretinoin 3.5316935849
MESH:D001528 Behcet Syndrome Colchicine 10.0315870978
MESH:D001528 Behcet Syndrome Sulfasalazine 10.0315870978
MESH:D001768 Blister Mustard Gas 4.2519167455
MESH:D001778 Blood Coagulation Disorders arsenic trioxide 6.4416206674
MESH:D001778 Blood Coagulation Disorders Tretinoin 6.4416197459 16206674
MESH:D001855 Bone Marrow Diseases Benzene 4.3116183116
MESH:D019046 Bone Marrow Neoplasms Doxorubicin 3.7814601052
MESH:D001859 Bone Neoplasms Paclitaxel 3.7215867366
MESH:D001862 Bone Resorption bisphenol A 11.3511985600
MESH:D001862 Bone Resorption Drugs, Chinese Herbal 11.359881647
MESH:D001862 Bone Resorption mangiferin 11.359881647
MESH:D001919 Bradycardia Phenylephrine 3.6515306635
MESH:D020201 Brain Hemorrhage, Traumatic Progesterone 4.4117868700
MESH:D001930 Brain Injuries Progesterone 3.3715665606 15845082 15380490
MESH:D002545 Brain Ischemia Curcumin 3.4416770732
MESH:D001932 Brain Neoplasms Curcumin 10.1517596214
MESH:D001932 Brain Neoplasms Doxorubicin 10.1517150277
MESH:D001932 Brain Neoplasms Fenretinide 10.1516187019
MESH:D001943 Breast Neoplasms Benzene 15.4517162533 11921183
MESH:D001943 Breast Neoplasms Benzo(a)pyrene 15.4520146248 17474063
MESH:D001943 Breast Neoplasms bisphenol A 15.4517123778
MESH:D001943 Breast Neoplasms Curcumin 15.4519250217 18462866 18593918 16243823
MESH:D001943 Breast Neoplasms DDT 15.4516792888 12709520
MESH:D001943 Breast Neoplasms Deferoxamine 15.4515993339
MESH:D001943 Breast Neoplasms Diethylnitrosamine 15.4517474063
MESH:D001943 Breast Neoplasms Doxorubicin 15.4515634643 16115903 15136595 17983394 16595493 18234424 19526202 15567936 18695136 16096432 15939500 15993339 16935488 18628466 16264153 15668708 17369602 17426702 18382427 11325840 16826403 15692762 15994142 16322301
MESH:D001943 Breast Neoplasms (E)-4-((2-N-(4-methoxybenzenesulfonyl)amino)stilbazole)1-oxide 15.4515528975
MESH:D001943 Breast Neoplasms Fenretinide 15.4516601279
MESH:D001943 Breast Neoplasms Oxygen 15.4517263869
MESH:D001943 Breast Neoplasms Paclitaxel 15.4516115903 15136595 11325840 16244791 16273361 18234424 18223236 18323546
MESH:D001943 Breast Neoplasms parthenolide 15.4516873071
MESH:D001943 Breast Neoplasms Progesterone 15.4515562024 16175315 17614352
MESH:D001943 Breast Neoplasms Quercetin 15.4518628248
MESH:D001943 Breast Neoplasms Sulfasalazine 15.4517356269
MESH:D001943 Breast Neoplasms Tamoxifen 15.4517440819 19189212 16873071 18855134 17261762 19189210 19066611 18351453 20390343 11161223 19142967 18815881 19059307 20135344 17242785 18629630 19288272 19221464 16273361 19200415 19410462 15565566 20065188 20859285 21138602 19084267 18997820 15668708 18821012 16202921 17049068 20544844 18425577 17893378 18984771 19115204 20005174 21152245 19487384 19155303 19244106 19011961 16818667 19289846 19103187
MESH:D001943 Breast Neoplasms Tretinoin 15.4516443354 16166294 16873071
MESH:D016535 Bronchial Hyperreactivity Ozone 2.9319059883 18315731 14754758 15516495 18417511 17626835 16777450
MESH:D001989 Bronchiolitis Obliterans Mustard Gas 4.2515286001
MESH:D029481 Bronchitis, Chronic Mustard Gas 4.0517687719 10378619
MESH:D001997 Bronchopulmonary Dysplasia Tretinoin 3.6816813970
MESH:D002051 Burkitt Lymphoma arsenic trioxide 3.4811589617
MESH:D002100 Cachexia Ozone 3.8316183385
MESH:D002105 Cadmium Poisoning Quercetin 4.6216962696
MESH:D002252 Carbon Tetrachloride Poisoning Carbon Tetrachloride 2.9016050911 3786805 16011737 15700767 18705752 16227642 16097048 15673190 16192424 15721981 10355542 16124888
MESH:D002276 Carcinoid Tumor Doxorubicin 3.8916051944
MESH:D002277 Carcinoma Curcumin 6.2418593918
MESH:D002277 Carcinoma Dimethylnitrosamine 6.2419555203
MESH:D002280 Carcinoma, Basal Cell Arsenic 2.9917687452 15504454
MESH:D018270 Carcinoma, Ductal, Breast Tamoxifen 3.6219066611
MESH:D018236 Carcinoma, Embryonal Tretinoin 4.2316168501
MESH:D006528 Carcinoma, Hepatocellular Acetaminophen 31.163084413
MESH:D006528 Carcinoma, Hepatocellular anthra(1,9-cd)pyrazol-6(2H)-one 31.1619418558
MESH:D006528 Carcinoma, Hepatocellular Arsenic 31.1616507464 17306315
MESH:D006528 Carcinoma, Hepatocellular arsenic trioxide 31.1611135700 15553829 14691202 16217749 15073043
MESH:D006528 Carcinoma, Hepatocellular Carbon Tetrachloride 31.1618788625
MESH:D006528 Carcinoma, Hepatocellular DDT 31.1612597452
MESH:D006528 Carcinoma, Hepatocellular Diethylnitrosamine 31.163084413 20432363 19919837 19519916 16502159 20101231 18788625 11831363 20084675 19822196 19701751 18056438 18506893 19335982 17761372 20935162 19052882 16779866 18785209 18665156 16328049 18971187 20727157 16681979 19539802 16569478 18393292 19383236 18210153 16540662 17978847 18691550 20514400 18978308 19171122 16698587 17138121 16935385 16807293 17162532 17173139 19418558 16288022 16830150 16878318 20007298 10672840 18494052 19208518 19394651 17055752 19107877 21159647 20512989 10737359 20214788 17428255 20524982 3581430
MESH:D006528 Carcinoma, Hepatocellular Doxorubicin 31.1616023760 18059187 17876044 16234567
MESH:D006528 Carcinoma, Hepatocellular Fenretinide 31.1617159502 16270382
MESH:D006528 Carcinoma, Hepatocellular malachite green 31.1612616621
MESH:D006528 Carcinoma, Hepatocellular Paclitaxel 31.1616313753
MESH:D006528 Carcinoma, Hepatocellular Quercetin 31.1612508355 19519916
MESH:D006528 Carcinoma, Hepatocellular sodium arsenite 31.1617306315 15276417 16507464
MESH:D006528 Carcinoma, Hepatocellular Tamoxifen 31.1616924424
MESH:D006528 Carcinoma, Hepatocellular Tretinoin 31.161917145
MESH:D002278 Carcinoma in Situ bisphenol A 4.0817123778
MESH:D002289 Carcinoma, Non-Small-Cell Lung 5-((4-methylphenyl)methylene)-2-(phenylamino)-4(5H)-thiazolone 4.9316179969
MESH:D002289 Carcinoma, Non-Small-Cell Lung Curcumin 4.9318414057
MESH:D021441 Carcinoma, Pancreatic Ductal Quercetin 4.0717234771
MESH:D002291 Carcinoma, Papillary arsenic trioxide 3.9519014326
MESH:D002292 Carcinoma, Renal Cell Doxorubicin 5.191485588 16201981
MESH:D002292 Carcinoma, Renal Cell Vinblastine 5.191485588
MESH:D018288 Carcinoma, Small Cell arsenic trioxide 3.3112490120
MESH:D002294 Carcinoma, Squamous Cell Arsenic 22.4918922899 15504454 17687452
MESH:D002294 Carcinoma, Squamous Cell Benzo(a)pyrene 22.4920419170
MESH:D002294 Carcinoma, Squamous Cell Curcumin 22.4918462866
MESH:D002294 Carcinoma, Squamous Cell Dimethylnitrosamine 22.4916033868
MESH:D002294 Carcinoma, Squamous Cell Doxorubicin 22.496189445
MESH:D002294 Carcinoma, Squamous Cell Fenretinide 22.4916274795
MESH:D002294 Carcinoma, Squamous Cell sodium arsenite 22.4918572023
MESH:D002294 Carcinoma, Squamous Cell Tetradecanoylphorbol Acetate 22.4918922899
MESH:D002294 Carcinoma, Squamous Cell Tretinoin 22.4916096774 16051514
MESH:D002295 Carcinoma, Transitional Cell Arsenic 6.8218640142
MESH:D002295 Carcinoma, Transitional Cell Tamoxifen 6.8217572228
MESH:D006332 Cardiomegaly Norepinephrine 8.2911179087
MESH:D006332 Cardiomegaly Phenylephrine 8.2917287366 15728586 16170337 17124262 11179087 11754973
MESH:D006332 Cardiomegaly Quercetin 8.2919794523
MESH:D009202 Cardiomyopathies Doxorubicin 2.8717382496 15505089 17308081 16364871 15811867 15476868 17007740 17329180 17974986 17351982 16612575 16952015 16242529 16269455 15792986 18627295 16455267 16109756 17924179 16651473 17928571 17131338 17519947 16731534 16278810
MESH:D002310 Cardiomyopathy, Alcoholic Acetaldehyde 5.5510525098
MESH:D002311 Cardiomyopathy, Dilated Doxorubicin 2.5417334414 16243910
MESH:D002318 Cardiovascular Diseases Arsenic 5.3115738583 19152805 17938729
MESH:D002318 Cardiovascular Diseases Hydrogen Peroxide 5.3116936243
MESH:D002340 Carotid Artery Diseases Arsenic 3.5218022660 16973168
MESH:D002375 Catalepsy Haloperidol 8.661977408 15215559
MESH:D002375 Catalepsy Norepinephrine 8.668216760
MESH:D002386 Cataract Acetaminophen 5.1710977129
MESH:D002386 Cataract Tretinoin 5.1717460283
MESH:D002471 Cell Transformation, Neoplastic 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 17.5720889678
MESH:D002471 Cell Transformation, Neoplastic Cadmium 17.5717332340
MESH:D002471 Cell Transformation, Neoplastic Cyclosporine 17.5712371664
MESH:D002471 Cell Transformation, Neoplastic Diethylnitrosamine 17.5717174075 2727394 7505956 21159647
MESH:D002471 Cell Transformation, Neoplastic Methylnitronitrosoguanidine 17.572727394
MESH:D002471 Cell Transformation, Neoplastic sodium arsenite 17.5719524636 20056578
MESH:D018290 Cervical Intraepithelial Neoplasia Fenretinide 9.9716154183
MESH:D018290 Cervical Intraepithelial Neoplasia Tretinoin 9.9716129372
MESH:D018281 Cholangiocarcinoma Diethylnitrosamine 2.9019052882
MESH:D002779 Cholestasis Cyclosporine 2.2119486331
MESH:D002822 Choriocarcinoma Tretinoin 4.2316461808
MESH:D019457 Chromosome Breakage Sodium Selenite 3.8615894690
MESH:D016770 Ciliophora Infections malachite green 4.8916175963 15900690
MESH:D002972 Cleft Palate Tretinoin 2.209407595
MESH:D003072 Cognition Disorders Clozapine 4.0817123785
MESH:D003092 Colitis Curcumin 10.9716804969 18200517 16782535
MESH:D003092 Colitis Selenium 10.9717936198
MESH:D003092 Colitis Tretinoin 10.9717035595
MESH:D003093 Colitis, Ulcerative Sulfasalazine 4.1417339853 15955209
MESH:D003103 Coloboma Curcumin 3.7218809619
MESH:D003110 Colonic Neoplasms arsenite 4.3615037631
MESH:D003110 Colonic Neoplasms Curcumin 4.3616340194 19359593
MESH:D003110 Colonic Neoplasms Quercetin 4.3617191121 11134977 19056647 15741050 17148506 19440933 16640504
MESH:D015179 Colorectal Neoplasms arsenic trioxide 6.2820501625
MESH:D015179 Colorectal Neoplasms Doxorubicin 6.2818259882 18802399
MESH:D015179 Colorectal Neoplasms Fenretinide 6.2817273769
MESH:D015179 Colorectal Neoplasms Paclitaxel 6.2818802399
MESH:D015179 Colorectal Neoplasms Quercetin 6.2818852136 18095365
MESH:D015179 Colorectal Neoplasms Vinblastine 6.2818802399
MESH:D000013 Congenital Abnormalities DDT 7.6115095906
MESH:D000013 Congenital Abnormalities Triclosan 7.6119283420
MESH:D016510 Corneal Neovascularization Curcumin 4.0118497527
MESH:D023903 Coronary Restenosis arsenic trioxide 3.3212609071
MESH:D019465 Craniofacial Abnormalities arsenic trioxide 4.0910525206
MESH:D019465 Craniofacial Abnormalities Benzene 4.0915643154
MESH:D019465 Craniofacial Abnormalities lead acetate 4.0919769572
MESH:D019465 Craniofacial Abnormalities Tretinoin 4.099142499 16925845 17551590 14991402 9211117 9125849 10589399 8800419 9664655 9224671
MESH:D003456 Cryptorchidism vinclozolin 3.4714966744
MESH:D003457 Cryptosporidiosis mangiferin 4.9416547730
MESH:D003550 Cystic Fibrosis Docosahexaenoic Acids 3.8819747007
MESH:D016757 Death, Sudden, Cardiac arsenic trioxide 8.1115213294
MESH:D016757 Death, Sudden, Cardiac Haloperidol 8.1120210726
MESH:D003704 Dementia Haloperidol 3.7611575062
MESH:D003711 Demyelinating Diseases Tamoxifen 3.4719031437
MESH:D003872 Dermatitis Benzene 3.8815902427
MESH:D003920 Diabetes Mellitus Metformin 7.1817446233
MESH:D003920 Diabetes Mellitus Sodium Selenite 7.1816285004
MESH:D003921 Diabetes Mellitus, Experimental mangiferin 6.3212093613 19028559
MESH:D003921 Diabetes Mellitus, Experimental Quercetin 6.3219496084
MESH:D003924 Diabetes Mellitus, Type 2 Clozapine 12.7316402076
MESH:D003924 Diabetes Mellitus, Type 2 Curcumin 12.7318403477
MESH:D003924 Diabetes Mellitus, Type 2 Diethylnitrosamine 12.7320387270
MESH:D003924 Diabetes Mellitus, Type 2 epigallocatechin gallate 12.7316988119
MESH:D003924 Diabetes Mellitus, Type 2 mangiferin 12.7311315760 9881663
MESH:D003924 Diabetes Mellitus, Type 2 Metformin 12.7321186350
MESH:D003925 Diabetic Angiopathies Metformin 5.1516385087
MESH:D003928 Diabetic Nephropathies Curcumin 10.6718204486
MESH:D003928 Diabetic Nephropathies mangiferin 10.6719960420 19706694
MESH:D003928 Diabetic Nephropathies Tamoxifen 10.6719279558
MESH:D003929 Diabetic Neuropathies Progesterone 3.6017187935
MESH:D006970 Disorders of Excessive Somnolence Clozapine 4.6315331141
MESH:D056486 Drug-Induced Liver Injury Acetaminophen 27.0014986274 16485898 17522070 11529661 12705907 19923254 19085960 2444490 11461765 10774834 16177239 15619225 15968718 12392966 16227642 19370779 12153990 19164858 17906064 16393943 11834606 11743745 14725611 11739529 19739265 14550746 12958197 12594235 19416960 16109766 11421492 12540782 10663392 19420014 16781746 17562736 11287661 18713872 16081117 18071297 10915739
MESH:D056486 Drug-Induced Liver Injury Carbon Tetrachloride 27.0011566570 7440962 15027814 9327722 7179309 15998439 10092053 16177239 2869522 21278145 6884620 17522070 19336974 16227642 7120509 4309450 3786805 6623471 3732212 19085960 10915739 15968718
MESH:D056486 Drug-Induced Liver Injury cyanoginosin LR 27.0017654400
MESH:D056486 Drug-Induced Liver Injury Diethylnitrosamine 27.0019107877
MESH:D056486 Drug-Induced Liver Injury Dimethylnitrosamine 27.008172417
MESH:D056486 Drug-Induced Liver Injury Diquat 27.0018164269 18445702
MESH:D056486 Drug-Induced Liver Injury Doxorubicin 27.0017416283
MESH:D056486 Drug-Induced Liver Injury Drugs, Chinese Herbal 27.0015027814
MESH:D056486 Drug-Induced Liver Injury manumycin 27.0019739265
MESH:D056486 Drug-Induced Liver Injury Selenium 27.0015131321
MESH:D056486 Drug-Induced Liver Injury Silymarin 27.0014998559
MESH:D056486 Drug-Induced Liver Injury Sodium Selenite 27.0015131321
MESH:D056487 Drug-Induced Liver Injury, Chronic Acetaminophen 3.1819426721
MESH:D004362 Drug Toxicity Doxorubicin 2.9618602426
MESH:D004381 Duodenal Ulcer Curcumin 3.2017351913
MESH:D050171 Dyslipidemias Clozapine 3.4816402076
MESH:D004417 Dyspnea DDT 7.8516487989
MESH:D004417 Dyspnea Oxygen 7.8520016425
MESH:D004487 Edema Mustard Gas 4.679260866 11428647 11428631 11402378
MESH:D004487 Edema Tetradecanoylphorbol Acetate 4.679599246 8113982 11698051 7812673 15177302 8273558 16716910
MESH:D004489 Edema, Cardiac Tretinoin 3.5518230668
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Progesterone 6.3117692515
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Tamoxifen 6.3119031437
MESH:D016889 Endometrial Neoplasms Doxorubicin 8.6517359293
MESH:D016889 Endometrial Neoplasms Tamoxifen 8.6519155303 16202921 17893378 20544844
MESH:D016889 Endometrial Neoplasms Tretinoin 8.6516569247
MESH:D004715 Endometriosis Progesterone 2.9716134523
MESH:D004719 Endomyocardial Fibrosis Doxorubicin 4.2318037988
MESH:D019446 Endotoxemia Lipopolysaccharides 3.5015328337 17637181 15821434
MESH:D004827 Epilepsy Norepinephrine 3.75821787
MESH:D004890 Erythema Mustard Gas 4.259357497
MESH:D004931 Esophageal Achalasia Diethylnitrosamine 4.1916302075
MESH:D004938 Esophageal Neoplasms 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 10.0320426865
MESH:D004938 Esophageal Neoplasms arsenic trioxide 10.0312903497
MESH:D004938 Esophageal Neoplasms Benzo(a)pyrene 10.0316530937
MESH:D004938 Esophageal Neoplasms Dimethylnitrosamine 10.0317016578
MESH:D004938 Esophageal Neoplasms Paclitaxel 10.0316481741
MESH:D005124 Eye Abnormalities Tretinoin 2.8516938888 9664655
MESH:D005234 Fatty Liver arsenic trioxide 33.7315073043
MESH:D005234 Fatty Liver arsenite 33.7318296743
MESH:D005234 Fatty Liver Carbon Tetrachloride 33.7312631006 16045604 12795759 61145 15959796 16239168 17595544 19224547
MESH:D005234 Fatty Liver Curcumin 33.7319297423
MESH:D005234 Fatty Liver Cyclosporine 33.7319224547
MESH:D005234 Fatty Liver Diethylnitrosamine 33.7320387270 21071580
MESH:D005234 Fatty Liver Fish Oils 33.7318620774
MESH:D005234 Fatty Liver mangiferin 33.7315975614
MESH:D005234 Fatty Liver Tamoxifen 33.7314986274 19224547
MESH:D052776 Female Urogenital Diseases Tamoxifen 2.6016709447
MESH:D005317 Fetal Growth Retardation lead acetate 4.5219769572
MESH:D005334 Fever Lipopolysaccharides 3.219205823 11852909
MESH:D018221 Fibromatosis, Abdominal Tamoxifen 3.6214745880
MESH:D018222 Fibromatosis, Aggressive Doxorubicin 8.4419069698
MESH:D018222 Fibromatosis, Aggressive Tamoxifen 8.4419069698
MESH:D005355 Fibrosis arsenite 23.2518296743
MESH:D005355 Fibrosis Carbon Tetrachloride 23.2518705752
MESH:D005355 Fibrosis Curcumin 23.2518705752
MESH:D005355 Fibrosis Cyclosporine 23.2512168785 12639820
MESH:D005355 Fibrosis Quercetin 23.2519474275
MESH:D005355 Fibrosis Tretinoin 23.2517994277
MESH:D005393 Fish Diseases malachite green 4.8515900690 16175963
MESH:D005534 Foot Diseases Arsenic 4.636392382
MESH:D005706 Gallbladder Neoplasms arsenic trioxide 3.3916904648
MESH:D005739 Gas Poisoning Oxygen 4.3020016425
MESH:D005756 Gastritis Acetaminophen 8.4016983495
MESH:D005756 Gastritis Diquat 8.4015046732
MESH:D005770 Gastrointestinal Neoplasms Curcumin 3.8118462866
MESH:D030342 Genetic Diseases, Inborn vinclozolin 4.0316973722
MESH:D005832 Genital Diseases, Male vinclozolin 4.3816417039
MESH:D005833 Genital Neoplasms, Female sodium arsenite 3.7716452187
MESH:D005885 Gingival Hyperplasia Cyclosporine 3.318708960
MESH:D005909 Glioblastoma Curcumin 23.4117596214
MESH:D005909 Glioblastoma Doxorubicin 23.4117150277
MESH:D005909 Glioblastoma Fenretinide 23.4116187019
MESH:D005909 Glioblastoma Manganese 23.4117043766
MESH:D005909 Glioblastoma myricetin 23.4119804834
MESH:D005909 Glioblastoma Quercetin 23.4119804834
MESH:D005909 Glioblastoma Tretinoin 23.4117312396
MESH:D005910 Glioma Quercetin 2.6017643826
MESH:D005911 Gliosis Paraquat 4.2411124998
MESH:D005922 Glomerulonephritis, IGA deoxynivalenol 4.2615173396 16524712
MESH:D006258 Head and Neck Neoplasms Curcumin 9.0918829502 18462866
MESH:D006258 Head and Neck Neoplasms Doxorubicin 9.0915692506
MESH:D006258 Head and Neck Neoplasms Tretinoin 9.0916096774
MESH:D006317 Hearing Loss, Noise-Induced Tretinoin 4.2316084493
MESH:D006330 Heart Defects, Congenital Benzo(a)pyrene 4.7420471113
MESH:D006330 Heart Defects, Congenital Tretinoin 4.749664655 14991402
MESH:D006331 Heart Diseases Doxorubicin 9.0618006777 16707910 14766674 18674790 16244372 12587719 16879835 16244371 16495754 16144979 17875725 17888722 16330681
MESH:D006331 Heart Diseases mangiferin 9.0612093613
MESH:D006331 Heart Diseases pifithrin 9.0614766674
MESH:D006333 Heart Failure Dobutamine 8.3717440445
MESH:D006333 Heart Failure Doxorubicin 8.3717481944
MESH:D006333 Heart Failure Selenium 8.3717162251
MESH:D006394 Hemangiosarcoma Doxorubicin 3.0915692506
MESH:D006402 Hematologic Diseases Benzene 3.8116183116
MESH:D006457 Hemoglobinuria, Paroxysmal Cyclosporine 3.5115720958
MESH:D006463 Hemolytic-Uremic Syndrome Lipopolysaccharides 3.5716366002
MESH:D006505 Hepatitis Carbon Tetrachloride 11.0319110552 19900420
MESH:D006505 Hepatitis DDT 11.0316487989
MESH:D006505 Hepatitis Drugs, Chinese Herbal 11.0318339527
MESH:D006529 Hepatomegaly DDT 3.882387028
MESH:D015417 Hereditary Sensory and Motor Neuropathy Curcumin 4.1517701891
MESH:D006561 Herpes Simplex mangiferin 4.1110715843
MESH:D006689 Hodgkin Disease Doxorubicin 7.9217606976 18501091 15147373
MESH:D006689 Hodgkin Disease sodium arsenite 7.9212676792
MESH:D006689 Hodgkin Disease Vinblastine 7.9218501091 18180244
MESH:D006930 Hyperalgesia Acetaminophen 5.1516870215
MESH:D006930 Hyperalgesia Tretinoin 5.1516870215
MESH:D017588 Hyperandrogenism Metformin 5.0717062894 15356085
MESH:D006932 Hyperbilirubinemia Carbon Tetrachloride 3.6216899240
MESH:D006937 Hypercholesterolemia Curcumin 3.2418704882
MESH:D017681 Hypereosinophilic Syndrome Tretinoin 3.6816778211
MESH:D006943 Hyperglycemia Quercetin 3.2318262572 11834736
MESH:D006946 Hyperinsulinism mangiferin 4.229881663 11315760
MESH:D017488 Hyperkeratosis, Epidermolytic Arsenic 3.6417050553
MESH:D006948 Hyperkinesis Clozapine 4.0116046005
MESH:D006949 Hyperlipidemias Fish Oils 7.2215752949
MESH:D006949 Hyperlipidemias mangiferin 7.2215975614
MESH:D006967 Hypersensitivity mangiferin 3.9016536907
MESH:D006968 Hypersensitivity, Delayed Fish Oils 4.5911484837
MESH:D006973 Hypertension Arsenic 11.5011953799 9931084 16076760
MESH:D006973 Hypertension Benzene 11.5017940673
MESH:D006973 Hypertension Cyclosporine 11.5010903974
MESH:D006973 Hypertension Phenylephrine 11.5012717712 8949925
MESH:D006973 Hypertension Quercetin 11.5018356687
MESH:D006975 Hypertension, Portal Carbon Tetrachloride 3.2015338365
MESH:D006984 Hypertrophy Phenylephrine 3.7318502941 12791704
MESH:D006987 Hypesthesia Arsenic 4.6316093927
MESH:D007022 Hypotension Norepinephrine 4.166740701
MESH:D007154 Immune System Diseases mangiferin 4.9416076520
MESH:D020244 Infarction, Middle Cerebral Artery pifithrin 8.9219475672
MESH:D020244 Infarction, Middle Cerebral Artery Progesterone 8.9215869954
MESH:D007248 Infertility, Male DDT 21.6317192596 17157474
MESH:D007248 Infertility, Male Diquat 21.634850670
MESH:D007248 Infertility, Male Paraquat 21.634850670
MESH:D007248 Infertility, Male sodium arsenite 21.6312646999 15346721
MESH:D007248 Infertility, Male Sulfasalazine 21.6310689203
MESH:D007248 Infertility, Male Triclosan 21.6320821571
MESH:D007248 Infertility, Male vinclozolin 21.6316467254
MESH:D007249 Inflammation Curcumin 25.2418403477 16956363 17151092
MESH:D007249 Inflammation Diethylnitrosamine 25.2418785209
MESH:D007249 Inflammation Lipopolysaccharides 25.2412878042 17255318 17237260 9205823 17963957
MESH:D007249 Inflammation mangiferin 25.2415222974
MESH:D007249 Inflammation Mustard Gas 25.2411428620 11428647 8975870 16001271 9260866 9357497 17524151 11402378 11428631
MESH:D007249 Inflammation Progesterone 25.2415869954
MESH:D007249 Inflammation Silymarin 25.2417213517
MESH:D007249 Inflammation Tamoxifen 25.2419457130
MESH:D007249 Inflammation Tetradecanoylphorbol Acetate 25.248273558 11698051 7812673 7562506 15177302
MESH:D007249 Inflammation Triclosan 25.2420507366 9584910
MESH:D015212 Inflammatory Bowel Diseases Curcumin 5.5018200517 18596194
MESH:D015212 Inflammatory Bowel Diseases Sulfasalazine 5.5015339030
MESH:D007251 Influenza, Human pyrrolidine dithiocarbamic acid 13.5118473937
MESH:D007251 Influenza, Human Quercetin 13.5116624496
MESH:D007251 Influenza, Human Selenium 13.5116624496
MESH:D007333 Insulin Resistance bisphenol A 12.3916393666
MESH:D007333 Insulin Resistance mangiferin 12.3911315760
MESH:D007333 Insulin Resistance Metformin 12.3917062894
MESH:D007333 Insulin Resistance Sodium Selenite 12.3914714311
MESH:D007410 Intestinal Diseases Tretinoin 2.8917994277
MESH:D007414 Intestinal Neoplasms Curcumin 3.4110783313
MESH:D019189 Iron Metabolism Disorders Lipopolysaccharides 3.7817255318
MESH:D007511 Ischemia mangiferin 4.3916806951
MESH:D007569 Jaw Abnormalities Tretinoin 3.0715992940 17551590
MESH:D007627 Keloid Quercetin 4.0717086741
MESH:D007638 Keratoconjunctivitis Sicca Cyclosporine 3.5215604871
MESH:D007642 Keratosis Arsenic 4.0812749816 16930632
MESH:D007674 Kidney Diseases Acetaminophen 23.3012587719 15629191
MESH:D007674 Kidney Diseases Cadmium 23.3016226777 16962696 16322080
MESH:D007674 Kidney Diseases Cadmium Chloride 23.3016962696
MESH:D007674 Kidney Diseases Cyclosporine 23.3010903974 18776723 8314463
MESH:D007674 Kidney Diseases Doxorubicin 23.3015699352 16775033 15369732
MESH:D007674 Kidney Diseases mangiferin 23.3012093613
MESH:D007674 Kidney Diseases Quercetin 23.3016962696
MESH:D007674 Kidney Diseases sodium arsenite 23.3020008137
MESH:D007676 Kidney Failure, Chronic Doxorubicin 11.9816707910
MESH:D007676 Kidney Failure, Chronic Hydrogen Peroxide 11.9816518626
MESH:D007676 Kidney Failure, Chronic Selenium 11.9816518626
MESH:D007680 Kidney Neoplasms Cyclosporine 4.7912371664
MESH:D007680 Kidney Neoplasms Tamoxifen 4.7918625569
MESH:D007859 Learning Disorders Colchicine 11.4811749816
MESH:D007859 Learning Disorders DDT 11.487589230
MESH:D007859 Learning Disorders mangiferin 11.4819182383
MESH:D007889 Leiomyoma Curcumin 3.7218555241
MESH:D007938 Leukemia 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one 17.4712970779
MESH:D007938 Leukemia arsenic trioxide 17.4715070760
MESH:D007938 Leukemia Benzene 17.4718335105 15935818 14694614 17119257
MESH:D007938 Leukemia Curcumin 17.4718462866
MESH:D007938 Leukemia Quercetin 17.4717468513
MESH:D007938 Leukemia Tretinoin 17.4717143497
MESH:D004915 Leukemia, Erythroblastic, Acute Doxorubicin 4.2316085563
MESH:D015451 Leukemia, Lymphocytic, Chronic, B-Cell Drugs, Chinese Herbal 3.4515802533
MESH:D015459 Leukemia-Lymphoma, Adult T-Cell arsenic trioxide 11.6417077332 12560223
MESH:D015459 Leukemia-Lymphoma, Adult T-Cell Curcumin 11.6416106398
MESH:D015459 Leukemia-Lymphoma, Adult T-Cell Docosahexaenoic Acids 11.6417077332
MESH:D007948 Leukemia, Monocytic, Acute anthra(1,9-cd)pyrazol-6(2H)-one 8.7816972261
MESH:D007948 Leukemia, Monocytic, Acute arsenic trioxide 8.7816972261
MESH:D015464 Leukemia, Myelogenous, Chronic, BCR-ABL Positive arsenic trioxide 6.4114633726
MESH:D015464 Leukemia, Myelogenous, Chronic, BCR-ABL Positive mangiferin 6.4115498116
MESH:D007951 Leukemia, Myeloid arsenic trioxide 11.2819077051
MESH:D007951 Leukemia, Myeloid Benzene 11.2817506065
MESH:D007951 Leukemia, Myeloid Tretinoin 11.2816482212 16932348 19285840
MESH:D015470 Leukemia, Myeloid, Acute arsenic trioxide 6.5316467208 20471514 17050201 19850784 16968895
MESH:D015470 Leukemia, Myeloid, Acute Benzene 6.5319478238
MESH:D015470 Leukemia, Myeloid, Acute Deferoxamine 6.5320368581
MESH:D015470 Leukemia, Myeloid, Acute Tretinoin 6.5317596541 16294345 19850784
MESH:D015473 Leukemia, Promyelocytic, Acute Arsenic 12.8317339181
MESH:D015473 Leukemia, Promyelocytic, Acute arsenic trioxide 12.8316891316 17217047 19035177 12018890 19075265 19225113 17649720 16331271 15213294 16330433 16823087 16966277 9834237 11161223 11468182 12679006 17107899 15748426 17712046 12712474 16112521 15622746 19642359 17869043 15336539
MESH:D015473 Leukemia, Promyelocytic, Acute dracorhodin 12.8316864444
MESH:D015473 Leukemia, Promyelocytic, Acute Tretinoin 12.8315748426 16788101 17339181 17294898 17368321 17712046 12679006 19642359 17107899 9834237 17217047 19075265 16140955 19035177 19225113 17649720 19029980 16891316 17506722 16823087 16766008 17361223 16331271 16935935 17301526
MESH:D015458 Leukemia, T-Cell arsenic trioxide 8.8316882451
MESH:D015458 Leukemia, T-Cell Curcumin 8.8316106398
MESH:D007970 Leukopenia Lipopolysaccharides 3.7915821434
MESH:D007972 Leukoplakia, Oral Fenretinide 5.1216707609
MESH:D007984 Leydig Cell Tumor vinclozolin 3.8216417039
MESH:D017880 Limb Deformities, Congenital Tretinoin 2.619224671
MESH:D008064 Lipidoses Clozapine 5.7417567588
MESH:D008064 Lipidoses Tamoxifen 5.7417567588 15342952
MESH:D008080 Liposarcoma Paclitaxel 3.9717353645
MESH:D008103 Liver Cirrhosis arsenite 14.5218296743
MESH:D008103 Liver Cirrhosis Carbon Tetrachloride 14.5217157831 16239168 17334410 11408273 17174718 16943688 16221502 21278145 11903743
MESH:D008103 Liver Cirrhosis Diethylnitrosamine 14.5220032147 18407596 18522880 19638242 18665156
MESH:D008103 Liver Cirrhosis Drugs, Chinese Herbal 14.5217163593
MESH:D008103 Liver Cirrhosis Silymarin 14.5217213517
MESH:D008106 Liver Cirrhosis, Experimental Carbon Tetrachloride 22.8515730626 18277467 12632514 18054572 15673190 15931870 15057751 14620537 10355542 18210741 17640975 16248980 18317297 18166357 16192424 16015684 18418968 18251166 15876570 16638106 18205269 17922224 15959796 12445418 17565644 12898905 16027843 14512876 17525996 18376398 11481614 18412020 13678700 15338365 14724832 17805973 15650968 17698563 18429990 15370692 17708605 17557913 20821823 12666154 17900296 15925388 18279442 16136751 16097048 14748882 18339082 17714472 16116963 17481882 15996030 12546737 12609069 18472332 12667390 17869086 17976157 15818738 16011737 12649538 18395095 18395914 18705752 12389079 18187930 18481824 18156304 18006644 12632512 18472094 17631135 17823541 15123356 14716496 15893842 15052691 12741479 15362042 17761835 17766677 18420326 12958196 17944888 17721639 16033810 14716833 12445421 18263696 12586293
MESH:D008106 Liver Cirrhosis, Experimental Curcumin 22.8517355460 18705752 18006644
MESH:D008106 Liver Cirrhosis, Experimental Dimethylnitrosamine 22.8515942678 18237412 17724770 15366600 15723089 18371158 15383259 17465448 15798949 18095165 15591649 12918455 18567088 17719030 15571005 15138612 15369754 17881167 14709902 18210741 14643895 17203207 16627068 15099470 16009107 15842777 18637143 15733078 16042886 17036385 16570917 12925901 15793283 14659978 17201889 17666798 17534399 15492853 17198567 17196135 16169303 15086199 15161499 16544323 15577212 15298665 16603200 17640959 14568256 15339415 15067225 15479170 15864749 16270385 18629640 17432682 18239293 18672772 15504291 17348192 15744066 15763062 14726149 18364076 15081153
MESH:D008106 Liver Cirrhosis, Experimental Doxorubicin 22.8516595196 16439617
MESH:D008106 Liver Cirrhosis, Experimental Drugs, Chinese Herbal 22.8515744066 15339415 18567088 15641146 12632512 17036385 15754396 17348192 15383259 17666798 18606216 17629604 15818738 16610055 15849816 15864749 18371158 15763062 17881167 18237412
MESH:D008106 Liver Cirrhosis, Experimental epigallocatechin gallate 22.8517481882
MESH:D008106 Liver Cirrhosis, Experimental Lipopolysaccharides 22.8512878042
MESH:D008106 Liver Cirrhosis, Experimental pyrrolidine dithiocarbamic acid 22.8515078482
MESH:D008106 Liver Cirrhosis, Experimental Quercetin 22.8512741479
MESH:D008106 Liver Cirrhosis, Experimental silybin 22.8516169303
MESH:D008106 Liver Cirrhosis, Experimental Silymarin 22.8515754394 15864749 17198567 18277467
MESH:D008106 Liver Cirrhosis, Experimental Sulfasalazine 22.8515633128
MESH:D008106 Liver Cirrhosis, Experimental Tamoxifen 22.8518564211
MESH:D008106 Liver Cirrhosis, Experimental Tretinoin 22.8516248980 18397230
MESH:D008107 Liver Diseases Acetaminophen 19.6419460945 12587719 12969438 16611625 19014921 11587558 19784758 16610002
MESH:D008107 Liver Diseases Arsenic 19.6411134558
MESH:D008107 Liver Diseases Carbon Tetrachloride 19.6415830285 15720792 16964402 17285989 16246199
MESH:D008107 Liver Diseases Curcumin 19.6416956363
MESH:D008107 Liver Diseases DDT 19.6415729006
MESH:D008107 Liver Diseases Diethylnitrosamine 19.6417034775
MESH:D008107 Liver Diseases Docosahexaenoic Acids 19.6417056761
MESH:D008107 Liver Diseases Drugs, Chinese Herbal 19.6417207593
MESH:D008107 Liver Diseases Silymarin 19.6417213517
MESH:D008108 Liver Diseases, Alcoholic Silymarin 5.0417213517
MESH:D017093 Liver Failure Carbon Tetrachloride 3.2815123358
MESH:D017114 Liver Failure, Acute Acetaminophen 11.6116871587 17185352
MESH:D017114 Liver Failure, Acute Carbon Tetrachloride 11.6114706259 16899240
MESH:D017114 Liver Failure, Acute Dimethylnitrosamine 11.6117457977
MESH:D008113 Liver Neoplasms Arsenic 34.4816368122
MESH:D008113 Liver Neoplasms arsenic trioxide 34.4814682389
MESH:D008113 Liver Neoplasms Benzo(a)pyrene 34.4821137059 20195826
MESH:D008113 Liver Neoplasms Carbon Tetrachloride 34.4819294768
MESH:D008113 Liver Neoplasms Clofibric Acid 34.4817602206
MESH:D008113 Liver Neoplasms DDT 34.4815975961 11948501
MESH:D008113 Liver Neoplasms Diethylnitrosamine 34.4820452335 2862719 20137499 18977376 12771043 19256749 19638242 18978307 19499222 20492335 21047994 19255062 21278145 9163691 19426721 19551842 18754104 18648771 19812893 21167192 19294768 10737359 18644402 19833225 12112319 2422723 19690152 20434301 19254457 19642983 15885732 19073162 20118626 15175105 20405173 16942905 20583210 19850985 20101389 19996281 19427195 20501860 19090486 21071580
MESH:D008113 Liver Neoplasms Dimethylnitrosamine 34.4815890375 3113478
MESH:D008113 Liver Neoplasms Drugs, Chinese Herbal 34.4818339527
MESH:D008113 Liver Neoplasms Quercetin 34.4818980244
MESH:D008113 Liver Neoplasms Silymarin 34.4819168119
MESH:D008113 Liver Neoplasms sodium arsenite 34.4816712894 15276417
MESH:D008113 Liver Neoplasms Tamoxifen 34.4816684651
MESH:D008114 Liver Neoplasms, Experimental arsenic trioxide 18.5320377131
MESH:D008114 Liver Neoplasms, Experimental Benzene 18.5312562636
MESH:D008114 Liver Neoplasms, Experimental Carbon Tetrachloride 18.5315583823 12014681
MESH:D008114 Liver Neoplasms, Experimental Diethylnitrosamine 18.5319009564 17942915 16267830 19519916 3124819 21159647 18775883 18093689 18544905 17854601 18079962 16842330 19539802 9362446 18308698 18253720 18164116 17174075 18282651 2563599 19004024 19126423
MESH:D008114 Liver Neoplasms, Experimental Dimethylnitrosamine 18.531848544 6150874 15603536
MESH:D008114 Liver Neoplasms, Experimental Doxorubicin 18.5316842330 17085340
MESH:D008114 Liver Neoplasms, Experimental Quercetin 18.5319519916
MESH:D008133 Long QT Syndrome arsenic trioxide 6.1915213294
MESH:D008133 Long QT Syndrome Dobutamine 6.1919353679
MESH:D008171 Lung Diseases 2-chloroethyl ethyl sulfide 20.1218675330 12815614 16252256
MESH:D008171 Lung Diseases chromium hexavalent ion 20.1216775837
MESH:D008171 Lung Diseases Dobutamine 20.1216638327
MESH:D008171 Lung Diseases Mustard Gas 20.1218161513 18702808
MESH:D008171 Lung Diseases Ozone 20.1219066396 8266340
MESH:D008171 Lung Diseases sodium arsenite 20.1219095001
MESH:D017563 Lung Diseases, Interstitial Benzene 3.8914698565
MESH:D055370 Lung Injury Lipopolysaccharides 14.5121114838
MESH:D055370 Lung Injury Oxygen 14.5118339021
MESH:D055370 Lung Injury Ozone 14.5120417186
MESH:D055370 Lung Injury pyrrolidine dithiocarbamic acid 14.5116129981
MESH:D008175 Lung Neoplasms Acetaldehyde 41.2317372256
MESH:D008175 Lung Neoplasms Arsenic 41.2319168569 17306315 17976673
MESH:D008175 Lung Neoplasms arsenic trioxide 41.2311798837 19825857
MESH:D008175 Lung Neoplasms arsenite 41.2316809336
MESH:D008175 Lung Neoplasms Benzene 41.2312562636
MESH:D008175 Lung Neoplasms Benzo(a)pyrene 41.2317053015 20064080 18520028 18569708 20135361 18816296 6695378 20869020 20464547
MESH:D008175 Lung Neoplasms chromium hexavalent ion 41.2316570259 16876463
MESH:D008175 Lung Neoplasms Curcumin 41.2318462866 19359593 16243823
MESH:D008175 Lung Neoplasms Diethylnitrosamine 41.2320512841 21163286 6695378 20970405
MESH:D008175 Lung Neoplasms Dimethylnitrosamine 41.2319555203 16061637 11884234
MESH:D008175 Lung Neoplasms Doxorubicin 41.2317418594 6189445
MESH:D008175 Lung Neoplasms Drugs, Chinese Herbal 41.2318339527
MESH:D008175 Lung Neoplasms (E)-4-((2-N-(4-methoxybenzenesulfonyl)amino)stilbazole)1-oxide 41.2315528975
MESH:D008175 Lung Neoplasms mangiferin 41.2318816296 18520028 18569708
MESH:D008175 Lung Neoplasms Mustard Gas 41.238781369 3148597
MESH:D008175 Lung Neoplasms Ozone 41.237614698 8597069
MESH:D008175 Lung Neoplasms Quercetin 41.2316280456
MESH:D008175 Lung Neoplasms silybin 41.2316788158
MESH:D008175 Lung Neoplasms sodium arsenite 41.2316712894 19931552 15276417 17077188 17306315
MESH:D008175 Lung Neoplasms Tamoxifen 41.2318625569
MESH:D008175 Lung Neoplasms Tetradecanoylphorbol Acetate 41.2311807781
MESH:D008223 Lymphoma Benzene 8.6417119257 17584886
MESH:D008223 Lymphoma Curcumin 8.6418462866
MESH:D008223 Lymphoma Doxorubicin 8.6416098063
MESH:D016393 Lymphoma, B-Cell Sodium Selenite 3.2214737004
MESH:D008228 Lymphoma, Non-Hodgkin Doxorubicin 6.4117654614
MESH:D008228 Lymphoma, Non-Hodgkin Paclitaxel 6.4114749477
MESH:D016399 Lymphoma, T-Cell Curcumin 8.6216173963
MESH:D016399 Lymphoma, T-Cell Doxorubicin 8.6215621674
MESH:D015674 Mammary Neoplasms, Animal Benzene 7.0912562636
MESH:D015674 Mammary Neoplasms, Animal Tamoxifen 7.0919428831
MESH:D008325 Mammary Neoplasms, Experimental Benzene 25.8511921183
MESH:D008325 Mammary Neoplasms, Experimental Doxorubicin 25.8515458769
MESH:D008325 Mammary Neoplasms, Experimental Drugs, Chinese Herbal 25.8514758024
MESH:D008325 Mammary Neoplasms, Experimental Fenretinide 25.8510697514
MESH:D008325 Mammary Neoplasms, Experimental Progesterone 25.8511408345 17203775
MESH:D008325 Mammary Neoplasms, Experimental Selenium 25.8515318939
MESH:D008325 Mammary Neoplasms, Experimental Tamoxifen 25.8511731420 16827153 14580682 19196723 19196722
MESH:D008325 Mammary Neoplasms, Experimental Tetradecanoylphorbol Acetate 25.858985016
MESH:D008325 Mammary Neoplasms, Experimental Triclosan 25.8515358634
MESH:D020149 Manganese Poisoning Manganese 9.9716551646 19453300 16568477
MESH:D020149 Manganese Poisoning Tamoxifen 9.9719453300
MESH:D008527 Medulloblastoma Tretinoin 2.3317453147
MESH:D008545 Melanoma Curcumin 21.5018462866 17885582
MESH:D008545 Melanoma Doxorubicin 21.5016827129
MESH:D008545 Melanoma dracorhodin 21.5015684474
MESH:D008545 Melanoma epigallocatechin gallate 21.5011746506 17992120
MESH:D008545 Melanoma Fenretinide 21.5016270382
MESH:D008545 Melanoma Glucose 21.5014993021
MESH:D008545 Melanoma Paclitaxel 21.5012025231 16342250 12040289
MESH:D008545 Melanoma sodium arsenite 21.5016487513 19082730
MESH:D008545 Melanoma Tamoxifen 21.5019393235 12393984
MESH:D008545 Melanoma Tretinoin 21.5016752155
MESH:D008545 Melanoma Vinblastine 21.5018176117 15577323 18332650 16809738 12374674 18505091 15577320 16248763 16432458 17761969
MESH:D018328 Melanoma, Amelanotic Tamoxifen 3.2815990972
MESH:D008546 Melanoma, Experimental Acetaminophen 2.6819513568
MESH:D008569 Memory Disorders Curcumin 7.1717263510
MESH:D008569 Memory Disorders mangiferin 7.1719182383
MESH:D008591 Meningomyelocele Tretinoin 3.5416940565
MESH:D001523 Mental Disorders Clozapine 5.4516856516
MESH:D001523 Mental Disorders Haloperidol 5.4516856516
MESH:D008654 Mesothelioma Doxorubicin 4.7117638057
MESH:D008654 Mesothelioma Selenium 4.7115107826
MESH:D024821 Metabolic Syndrome X Clozapine 3.6419142101
MESH:D008664 Metal Metabolism, Inborn Errors Cyclosporine 3.8616801185
MESH:D008679 Metaplasia Ozone 4.1810496685
MESH:D008708 Methemoglobinemia malachite green 4.6418363129
MESH:D053842 Microsatellite Instability Methylnitronitrosoguanidine 4.9817671175
MESH:D028361 Mitochondrial Diseases Doxorubicin 3.6715792986
MESH:D009062 Mouth Neoplasms Benzo(a)pyrene 6.3316381670
MESH:D009062 Mouth Neoplasms Fenretinide 6.3316274795
MESH:D009069 Movement Disorders Manganese 4.1616551646
MESH:D052016 Mucositis Doxorubicin 3.8817415656
MESH:D009101 Multiple Myeloma arsenic trioxide 11.6011468182 19417148 19549372 14977855 15949261
MESH:D009101 Multiple Myeloma Benzene 11.6017119195
MESH:D009101 Multiple Myeloma Curcumin 11.6019372569
MESH:D009101 Multiple Myeloma Paclitaxel 11.6014749477
MESH:D009134 Muscular Atrophy, Spinal Curcumin 9.6417962980
MESH:D009134 Muscular Atrophy, Spinal epigallocatechin gallate 9.6417962980
MESH:D009145 Mushroom Poisoning Silymarin 6.0117213517
MESH:D009182 Mycosis Fungoides arsenic trioxide 3.7518349030
MESH:D009190 Myelodysplastic Syndromes arsenic trioxide 5.3616882451 16105982
MESH:D009190 Myelodysplastic Syndromes Tretinoin 5.3617596541
MESH:D009203 Myocardial Infarction Doxorubicin 6.8819429709 15857846
MESH:D009203 Myocardial Infarction mangiferin 6.8816538859 19172585 17052832 16584858 16697266
MESH:D009203 Myocardial Infarction Quercetin 6.8819595682
MESH:D017202 Myocardial Ischemia Arsenic 7.2315371236
MESH:D017202 Myocardial Ischemia Dobutamine 7.2312447174
MESH:D015428 Myocardial Reperfusion Injury Norepinephrine 6.6915642760
MESH:D015428 Myocardial Reperfusion Injury Quercetin 6.6919207477
MESH:D009361 Neoplasm Invasiveness arsenic trioxide 7.4616624393
MESH:D009361 Neoplasm Invasiveness Curcumin 7.4618495463
MESH:D009362 Neoplasm Metastasis Diethylnitrosamine 12.889029167 3581430
MESH:D009362 Neoplasm Metastasis Doxorubicin 12.8818259882
MESH:D009362 Neoplasm Metastasis Paclitaxel 12.8815867366
MESH:D009362 Neoplasm Metastasis pentaacetyl geniposide 12.8819464279
MESH:D009362 Neoplasm Metastasis Tamoxifen 12.8819393235
MESH:D009364 Neoplasm Recurrence, Local Tamoxifen 2.1319410462
MESH:D009369 Neoplasms Benzo(a)pyrene 12.7111141357
MESH:D009369 Neoplasms DDT 12.718820588
MESH:D009369 Neoplasms Fenretinide 12.7115958647 17353921
MESH:D009369 Neoplasms Quercetin 12.7115185748
MESH:D009369 Neoplasms sodium arsenite 12.7111559025
MESH:D009369 Neoplasms Tretinoin 12.7116594593 16946489
MESH:D009374 Neoplasms, Experimental sodium arsenite 2.8020056578
MESH:D009376 Neoplasms, Hormone-Dependent Curcumin 7.8012497104
MESH:D009376 Neoplasms, Hormone-Dependent Tamoxifen 7.8019189210 19200415 19196722
MESH:D009389 Neovascularization, Pathologic arsenite 7.8215738583
MESH:D009389 Neovascularization, Pathologic parthenolide 7.8216921510
MESH:D009401 Nephrosis Doxorubicin 3.8816636307 16899518
MESH:D009402 Nephrosis, Lipoid Cyclosporine 3.5217954296
MESH:D009404 Nephrotic Syndrome Cyclosporine 6.6818481113 19348381
MESH:D009404 Nephrotic Syndrome Doxorubicin 6.6816889571 15640375
MESH:D009410 Nerve Degeneration 1-Methyl-4-phenylpyridinium 18.4717433543
MESH:D009410 Nerve Degeneration Manganese 18.4716551646
MESH:D009410 Nerve Degeneration mangiferin 18.4717433543
MESH:D009410 Nerve Degeneration Paraquat 18.4716893418
MESH:D009410 Nerve Degeneration Rotenone 18.4715790535 17356569 18619942
MESH:D009421 Nervous System Malformations bisphenol A 6.9316427766 11399458
MESH:D009421 Nervous System Malformations Tretinoin 6.939125849
MESH:D009423 Nervous System Neoplasms Curcumin 4.7118462866
MESH:D009436 Neural Tube Defects Arsenic 15.7916620997
MESH:D009436 Neural Tube Defects arsenic trioxide 15.7910525206
MESH:D009436 Neural Tube Defects Benzene 15.7915643154
MESH:D009436 Neural Tube Defects sodium arsenite 15.7912854658
MESH:D009436 Neural Tube Defects Tretinoin 15.799142499
MESH:D009447 Neuroblastoma Doxorubicin 2.7115555623
MESH:D019636 Neurodegenerative Diseases 1-Methyl-4-phenylpyridinium 9.7916353238
MESH:D019636 Neurodegenerative Diseases Acetaminophen 9.7918514411
MESH:D019636 Neurodegenerative Diseases Diethylnitrosamine 9.7920387270
MESH:D020078 Neurogenic Inflammation Arsenic 7.8817056641
MESH:D020078 Neurogenic Inflammation Quercetin 7.8817929310
MESH:D009461 Neurologic Manifestations Diethylnitrosamine 4.1920387270
MESH:D009472 Neuronal Ceroid-Lipofuscinoses Fenretinide 4.7716303764
MESH:D009503 Neutropenia Mustard Gas 6.8316761898 7688884
MESH:D009503 Neutropenia Vinblastine 6.8317378895
MESH:D009669 Nose Neoplasms chromium hexavalent ion 4.2316876463
MESH:D009765 Obesity 2-chloroethyl ethyl sulfide 5.7916289378
MESH:D009765 Obesity Clozapine 5.7919142110 18515891
MESH:D009765 Obesity Curcumin 5.7919297423
MESH:D009784 Occupational Diseases Benzene 3.3815935809 15727169 15913788 17479406 15576619 17119257 16737584 17178637 15612468
MESH:D010014 Osteolysis Paclitaxel 4.0815867366
MESH:D010024 Osteoporosis Curcumin 2.8518719352
MESH:D015663 Osteoporosis, Postmenopausal Drugs, Chinese Herbal 7.6716548355
MESH:D015663 Osteoporosis, Postmenopausal Quercetin 7.6719495926
MESH:D012516 Osteosarcoma Doxorubicin 3.3515930896
MESH:D010049 Ovarian Diseases bisphenol A 4.0811985600
MESH:D010051 Ovarian Neoplasms 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one 34.2616211241
MESH:D010051 Ovarian Neoplasms Arsenic 34.2617306315
MESH:D010051 Ovarian Neoplasms arsenic trioxide 34.2616624393 19769630 12452020
MESH:D010051 Ovarian Neoplasms Benzene 34.2612562636
MESH:D010051 Ovarian Neoplasms Curcumin 34.2619020741 18462866
MESH:D010051 Ovarian Neoplasms (E)-4-((2-N-(4-methoxybenzenesulfonyl)amino)stilbazole)1-oxide 34.2615528975
MESH:D010051 Ovarian Neoplasms Fenretinide 34.2616133793
MESH:D010051 Ovarian Neoplasms Paclitaxel 34.2611161223
MESH:D010051 Ovarian Neoplasms Progesterone 34.2617393432 16525653
MESH:D010051 Ovarian Neoplasms Quercetin 34.2619005980
MESH:D010051 Ovarian Neoplasms sodium arsenite 34.2615276417 17306315
MESH:D010051 Ovarian Neoplasms Tretinoin 34.2616936753
MESH:D010146 Pain Acetaminophen 4.1216870215
MESH:D010146 Pain Tretinoin 4.1216870215
MESH:D010190 Pancreatic Neoplasms arsenic trioxide 18.0315580305
MESH:D010190 Pancreatic Neoplasms Curcumin 18.0319196508 19401701 17440100
MESH:D010190 Pancreatic Neoplasms Diethylnitrosamine 18.0316540662
MESH:D010190 Pancreatic Neoplasms Fenretinide 18.0315580305
MESH:D010190 Pancreatic Neoplasms Quercetin 18.0316965848
MESH:D010190 Pancreatic Neoplasms Tetradecanoylphorbol Acetate 18.0315976015
MESH:D010190 Pancreatic Neoplasms Tretinoin 18.0315976015
MESH:D010212 Papilloma Hydrogen Peroxide 6.7012065085
MESH:D010212 Papilloma Tetradecanoylphorbol Acetate 6.708330346 18922899 12065085 18404319
MESH:D010235 Paraganglioma arsenic trioxide 3.3119927285
MESH:D010300 Parkinson Disease 1-Methyl-4-phenylpyridinium 11.5217433543
MESH:D010300 Parkinson Disease Manganese 11.5211181820
MESH:D010300 Parkinson Disease mangiferin 11.5217433543
MESH:D010300 Parkinson Disease Paraquat 11.5215824117 12911755 16140633 11445065 16510128 15451049 11181820 11124998
MESH:D010300 Parkinson Disease Rotenone 11.5215451049 18619942 19114014 16140633 11445065 18191903 11535288 19232380 16412576
MESH:D010302 Parkinson Disease, Secondary Paraquat 3.5516190885
MESH:D020734 Parkinsonian Disorders Manganese 6.8416140633
MESH:D020734 Parkinsonian Disorders Rotenone 6.8415927086 15574749 15795934 18197244
MESH:D010518 Periodontitis mangiferin 4.6819026997
MESH:D010523 Peripheral Nervous System Diseases Arsenic 3.3216093927
MESH:D016491 Peripheral Vascular Diseases Arsenic 10.0816905509 6392382 15371236
MESH:D016491 Peripheral Vascular Diseases Cadmium 10.0815687053
MESH:D010538 Peritonitis Ozone 3.2516369182
MESH:D003557 Phyllodes Tumor Doxorubicin 4.2317983394
MESH:D010954 Plasmacytoma Selenium 3.9715087411
MESH:D010997 Pleural Neoplasms Doxorubicin 4.2317638057
MESH:D011014 Pneumonia Lipopolysaccharides 13.3812224865 11605937
MESH:D011014 Pneumonia Ozone 13.3818381685 18929643 18007984
MESH:D011014 Pneumonia Paraquat 13.3812504350
MESH:D011041 Poisoning Mustard Gas 2.9715727166
MESH:D011085 Polycystic Ovary Syndrome Metformin 4.7117062894 15356085
MESH:D011230 Precancerous Conditions marker/mechanism 21317887
MESH:D011230 Precancerous Conditions Cyclosporine 10.7712371664
MESH:D011230 Precancerous Conditions Diethylnitrosamine 10.772563599
MESH:D011230 Precancerous Conditions Quercetin 10.7719056647
MESH:D011297 Prenatal Exposure Delayed Effects bisphenol A 6.7910548101
MESH:D011297 Prenatal Exposure Delayed Effects vinclozolin 6.7918220299 18042343 19015723
MESH:D011469 Prostatic Diseases vinclozolin 4.0318220299
MESH:D019048 Prostatic Intraepithelial Neoplasia bisphenol A 3.3820887781
MESH:D011471 Prostatic Neoplasms Arsenic 8.0116140617
MESH:D011471 Prostatic Neoplasms arsenic trioxide 8.0119131511
MESH:D011471 Prostatic Neoplasms Benzo(a)pyrene 8.0117292933
MESH:D011471 Prostatic Neoplasms bisphenol A 8.0116740699
MESH:D011471 Prostatic Neoplasms Cadmium 8.0117075824
MESH:D011471 Prostatic Neoplasms Curcumin 8.0111398177 18226269 18769126 18156803 15129424 10851300 12497104
MESH:D011471 Prostatic Neoplasms DDT 8.0112584743
MESH:D011471 Prostatic Neoplasms Doxorubicin 8.0116868541 15749863 16888761 16729912 15897917 18437689
MESH:D011471 Prostatic Neoplasms Fenretinide 8.0117024972
MESH:D011471 Prostatic Neoplasms methylselenic acid 8.0116205645
MESH:D011471 Prostatic Neoplasms Paclitaxel 8.0117172428 17136230 16729912 16356831
MESH:D011471 Prostatic Neoplasms parthenolide 8.0116921510
MESH:D011471 Prostatic Neoplasms pyrrolidine dithiocarbamic acid 8.0116139439
MESH:D011471 Prostatic Neoplasms Quercetin 8.0117292933 14715546
MESH:D011471 Prostatic Neoplasms sodium arsenite 8.0116039940
MESH:D011471 Prostatic Neoplasms Sodium Selenite 8.0118760546
MESH:D011471 Prostatic Neoplasms Tamoxifen 8.0115067354
MESH:D011472 Prostatitis vinclozolin 4.0318629315
MESH:D011507 Proteinuria Arsenic 6.4921343184
MESH:D011507 Proteinuria Tretinoin 6.4916636307
MESH:D011537 Pruritus Mustard Gas 3.2018058305
MESH:D011565 Psoriasis Cyclosporine 1.8216882103
MESH:D011595 Psychomotor Agitation Haloperidol 4.0711575062
MESH:D011618 Psychotic Disorders Clozapine 6.8015331141
MESH:D011618 Psychotic Disorders Haloperidol 6.8011575062
MESH:D011625 Pterygium Tretinoin 3.8816723453
MESH:D011629 Puberty, Precocious bisphenol A 3.8810548101
MESH:D011656 Pulmonary Emphysema Curcumin 3.7119168576
MESH:D011658 Pulmonary Fibrosis Drugs, Chinese Herbal 6.7516987627
MESH:D011658 Pulmonary Fibrosis Mustard Gas 6.7517266442 10334151 17894541 17720292 17620002
MESH:D011658 Pulmonary Fibrosis Paraquat 6.7517997886 16324872
MESH:D011833 Radiation Injuries, Experimental mangiferin 5.4815830843
MESH:D012003 Rectal Fistula Drugs, Chinese Herbal 5.0415043669
MESH:D051437 Renal Insufficiency Doxorubicin 3.3417922066
MESH:D012128 Respiratory Distress Syndrome, Adult 2-chloroethyl ethyl sulfide 19.4518257742 16292752 12210543
MESH:D012128 Respiratory Distress Syndrome, Adult Curcumin 19.4518379247 10666014
MESH:D012128 Respiratory Distress Syndrome, Adult Oxygen 19.4517627322 18339021
MESH:D012128 Respiratory Distress Syndrome, Adult Paraquat 19.4511700416
MESH:D012128 Respiratory Distress Syndrome, Adult pyrrolidine dithiocarbamic acid 19.4516129981
MESH:D012130 Respiratory Hypersensitivity Lipopolysaccharides 3.0710835634
MESH:D012135 Respiratory Sounds Paraquat 3.1811874814
MESH:D012162 Retinal Degeneration Fenretinide 6.8816303925
MESH:D012162 Retinal Degeneration Paraquat 6.8816458197
MESH:D012208 Rhabdomyosarcoma Tretinoin 3.2516116481 16283617
MESH:D012220 Rhinitis Acetaldehyde 3.9517050345
MESH:D012221 Rhinitis, Allergic, Perennial Drugs, Chinese Herbal 4.3615015336
MESH:D012468 Salivary Gland Neoplasms Progesterone 2.4418045962
MESH:D012509 Sarcoma Curcumin 11.3518462866
MESH:D012509 Sarcoma Doxorubicin 11.3515625365 18313854 16767912 17203757 15675481 17710206
MESH:D012509 Sarcoma Polysaccharides 11.3518753065
MESH:D012512 Sarcoma, Ewing's arsenic trioxide 7.4116646077
MESH:D012512 Sarcoma, Ewing's Doxorubicin 7.4116326096 14601052
MESH:D012514 Sarcoma, Kaposi Doxorubicin 3.8817846226
MESH:D012554 Schistosomiasis japonica Quercetin 4.6216862918
MESH:D012559 Schizophrenia Clozapine 3.3720521320 18855531 17667964 20521326 17123785 20580759 18806925 11763009 19369910 20452607 11151749 17726453 16141801 20107430 20168265
MESH:D012559 Schizophrenia Haloperidol 3.371830565 19369910 20107430 18513383
MESH:D018805 Sepsis Curcumin 3.3118389075
MESH:D012772 Shock, Septic mangiferin 4.3415177305
MESH:D012852 Sinusitis Phenylephrine 3.807327846
MESH:D012871 Skin Diseases Arsenic 3.986392382 17938729 17050553 15952646 16353154 19834688 17548696 18709164 16759981 17453740 16702368
MESH:D012871 Skin Diseases Mustard Gas 3.9815451306 16961503 12880345
MESH:D012878 Skin Neoplasms Arsenic 26.4717976673 16251483 17029826 17050553 19538983 15504454
MESH:D012878 Skin Neoplasms Benzo(a)pyrene 26.4719755658 10029692
MESH:D012878 Skin Neoplasms Doxorubicin 26.4715692506
MESH:D012878 Skin Neoplasms Fenretinide 26.4716467112
MESH:D012878 Skin Neoplasms Glucose 26.4714993021
MESH:D012878 Skin Neoplasms Hydrogen Peroxide 26.4712065085
MESH:D012878 Skin Neoplasms sodium arsenite 26.4718572023 19524636
MESH:D012878 Skin Neoplasms Tetradecanoylphorbol Acetate 26.4711807781 18404319 12065085 8330346 8985016
MESH:D012878 Skin Neoplasms Tretinoin 26.4716467112
MESH:D012983 Soft Tissue Neoplasms Doxorubicin 3.6817203757 15625365 16767912
MESH:D013088 Spermatocele Tamoxifen 3.3716709447
MESH:D013119 Spinal Cord Injuries Progesterone 7.8815862959 16503802
MESH:D013119 Spinal Cord Injuries Tamoxifen 7.8819457130
MESH:D016135 Spinal Dysraphism sodium arsenite 3.0512854658
MESH:D013158 Splenic Diseases aniline 10.5715694462
MESH:D013158 Splenic Diseases Dimethylnitrosamine 10.5712587719
MESH:D013274 Stomach Neoplasms arsenic trioxide 11.4617007042
MESH:D013274 Stomach Neoplasms Benzene 11.4612562636
MESH:D013274 Stomach Neoplasms Benzo(a)pyrene 11.462093021 20155912
MESH:D013274 Stomach Neoplasms Diethylnitrosamine 11.4618456281
MESH:D013274 Stomach Neoplasms Dimethylnitrosamine 11.4616033868
MESH:D013274 Stomach Neoplasms Docosahexaenoic Acids 11.4619015929
MESH:D013274 Stomach Neoplasms Drugs, Chinese Herbal 11.4618339527
MESH:D013274 Stomach Neoplasms Paclitaxel 11.4618506536 18396642
MESH:D013274 Stomach Neoplasms Tretinoin 11.4617261132
MESH:D013276 Stomach Ulcer Curcumin 5.1719188055 16631530
MESH:D013276 Stomach Ulcer mangiferin 5.1717918041
MESH:D013345 Subarachnoid Hemorrhage Drugs, Chinese Herbal 10.6217634840
MESH:D013345 Subarachnoid Hemorrhage pifithrin 10.6218364113
MESH:D019966 Substance-Related Disorders bisphenol A 3.0916684133 16045194
MESH:D013398 Sudden Infant Death Oxygen 4.6412563064
MESH:D013610 Tachycardia Norepinephrine 4.573261545
MESH:D017180 Tachycardia, Ventricular Haloperidol 3.8520210726
MESH:D024801 Tauopathies Camptothecin 8.8416930453
MESH:D024801 Tauopathies Paclitaxel 8.8416930453
MESH:D013921 Thrombocytopenia Lipopolysaccharides 3.3615821434
MESH:D013953 Thymus Neoplasms Benzene 4.0510850423
MESH:D013959 Thyroid Diseases Triclosan 5.0619910387
MESH:D013964 Thyroid Neoplasms 4-amino-5-(4-methylphenyl)-7-(tert-butyl)pyrazolo(3,4-d)pyrimidine 14.8316940797
MESH:D013964 Thyroid Neoplasms arsenic trioxide 14.8319014326
MESH:D013964 Thyroid Neoplasms Diethylnitrosamine 14.837505956
MESH:D013964 Thyroid Neoplasms Doxorubicin 14.8317909728 16010429
MESH:D013964 Thyroid Neoplasms Tretinoin 14.8317045167 16026305
MESH:D014062 Tongue Neoplasms Tretinoin 2.9816051514
MESH:D016171 Torsades de Pointes arsenic trioxide 7.7015213294
MESH:D016171 Torsades de Pointes Dobutamine 7.7019353679
MESH:D014235 Trichinellosis mangiferin 5.1414669257
MESH:D014376 Tuberculosis Tretinoin 2.5916040207
MESH:D001749 Urinary Bladder Neoplasms Arsenic 23.6411144890 17976673 19429237 19322015 15987713 17306315 18640142
MESH:D001749 Urinary Bladder Neoplasms arsenic trioxide 23.6412845720 20435036 12973940 11780464
MESH:D001749 Urinary Bladder Neoplasms Benzo(a)pyrene 23.6417053015
MESH:D001749 Urinary Bladder Neoplasms Curcumin 23.6418593936
MESH:D001749 Urinary Bladder Neoplasms Doxorubicin 23.6417653716
MESH:D001749 Urinary Bladder Neoplasms Fenretinide 23.6416720286
MESH:D001749 Urinary Bladder Neoplasms Quercetin 23.6416720314
MESH:D001749 Urinary Bladder Neoplasms sodium arsenite 23.6416452187 16712894 11723127 17306315
MESH:D001749 Urinary Bladder Neoplasms Tamoxifen 23.6417572228 16712894 8653321
MESH:D014565 Urogenital Neoplasms Curcumin 4.3618462866
MESH:D014570 Urologic Diseases DDT 4.7216487989
MESH:D014581 Urticaria Acetaminophen 2.1510982225
MESH:D002583 Uterine Cervical Neoplasms Fenretinide 11.3016154183
MESH:D002583 Uterine Cervical Neoplasms sodium arsenite 11.3011813266
MESH:D002583 Uterine Cervical Neoplasms Tretinoin 11.3016129372
MESH:D014591 Uterine Diseases bisphenol A 4.0814652134
MESH:D014594 Uterine Neoplasms Benzene 3.4812562636
MESH:D014604 Uveal Neoplasms Tretinoin 3.6916752155
MESH:D014605 Uveitis Cyclosporine 3.061336536
MESH:D014625 Vaginal Neoplasms Vinblastine 4.1615577323
MESH:D014652 Vascular Diseases Arsenic 8.8517056641
MESH:D014652 Vascular Diseases sodium arsenite 8.8517056641
MESH:D020301 Vasospasm, Intracranial pifithrin 4.7118364113
MESH:D018487 Ventricular Dysfunction, Left Doxorubicin 3.3417638931 16364871 17678736 17334414
MESH:D014820 Vitiligo Tretinoin 3.1916761959
MESH:D015430 Weight Gain Clozapine 3.6820564506 20107430 16402076 17502770 20521320 16141801
MESH:D015431 Weight Loss Clozapine 4.1717933447
MESH:D009396 Wilms Tumor Tretinoin 3.1716287080
MESH:D014947 Wounds and Injuries Drugs, Chinese Herbal 3.7816313111
MESH:D014985 Xerophthalmia Cyclosporine 3.5217120751
Pathway ID Pathway Name
KEGG:04920 Adipocytokine signaling pathway
KEGG:05142 Chagas disease (American trypanosomiasis)
KEGG:05210 Colorectal cancer
KEGG:05120 Epithelial cell signaling in Helicobacter pylori infection
KEGG:04012 ErbB signaling pathway
KEGG:04664 Fc epsilon RI signaling pathway
KEGG:04510 Focal adhesion
KEGG:04912 GnRH signaling pathway
KEGG:05160 Hepatitis C
REACT:25035 Innate immune response mediated by toll like receptors
KEGG:04910 Insulin signaling pathway
KEGG:04010 MAPK signaling pathway
KEGG:04722 Neurotrophin signaling pathway
KEGG:04621 NOD-like receptor signaling pathway
KEGG:04380 Osteoclast differentiation
KEGG:05212 Pancreatic cancer
KEGG:05200 Pathways in cancer
KEGG:04914 Progesterone-mediated oocyte maturation
KEGG:04141 Protein processing in endoplasmic reticulum
KEGG:04622 RIG-I-like receptor signaling pathway
KEGG:05131 Shigellosis
REACT:6900 Signaling in Immune system
KEGG:04660 T cell receptor signaling pathway
KEGG:04620 Toll-like receptor signaling pathway
KEGG:05145 Toxoplasmosis
KEGG:05152 Tuberculosis
KEGG:04930 Type II diabetes mellitus
KEGG:04310 Wnt signaling pathway
Pharmacogenomics Knowledge Base Top
  • PharmGKB Accession:PA30630
  • No data
    Releated disease ID Related disease Name
    PA445062Neoplasms
    Releated drug ID Related drug Name
    PA451578tacrolimus
    PA7000sorafenib
    Drug Bank Top
    Drugbank ID Action Drug Name Description
    DB07020 - N-{3-[5-(1H-1,2,4-triazol-3-yl)-1H-indazol-3-yl]phenyl}furan-2-carboxamide
    No data
    No data
    No data

    Simple Query:


      (e.g. CHD8)

    Syndromic Genes

    Non-syndromic Genes

    AutismKB Statistics

    • Studies: 1,036
    • Genes: 1,379
    • CNVs/SVs: 5,420
    • SNVs/Indels: 11,669
    • de novo Mutations: 5,669
    • Mosaics: 789
    • Linkage Regions: 172
    • Paper Collected: 6/30/2018
    • Last Update: 8/26/2018