AutismKB 2.0

Annotation Detail for PCDHB9


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Basic Information Top
Gene Symbol:PCDHB9 ( MGC119555,MGC119556,PCDH-BETA9,PCDH3H )
Gene Full Name: protocadherin beta 9
Band: 5q31.3
Quick LinksEntrez ID:56127; OMIM: 606335; Uniprot ID:PCDB9_HUMAN; ENSEMBL ID: ENSG00000120324; HGNC ID: 8694
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
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Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C009505 4,4'-diaminodiphenylmethane 4,4'-diaminodiphenylmethane results in increased expression of PCDHB9 mRNAincreases expression 18648102
D001151 Arsenic Arsenic results in decreased expression of PCDHB9 mRNAdecreases expression 19654921
D008748 Methylcholanthrene Methylcholanthrene results in decreased expression of PCDHB9 mRNAdecreases expression 20713471
D014415 Tunicamycin Tunicamycin results in decreased expression of PCDHB9 mRNAdecreases expression 17127020
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000236 Adenoma 4,4'-diaminodiphenylmethane 7.603712494
MESH:D000236 Adenoma Methylcholanthrene 7.606695378 10545420
MESH:D018246 Adrenocortical Adenoma Arsenic 5.9417306315
MESH:D020261 Arsenic Poisoning Arsenic 2.9518414634 12569548 16251483 16835338
MESH:D050197 Atherosclerosis Arsenic 7.6712928151 19371607
MESH:D050197 Atherosclerosis Methylcholanthrene 7.6711922910
MESH:D001660 Biliary Tract Diseases 4,4'-diaminodiphenylmethane 5.741440618 11289319
MESH:D001943 Breast Neoplasms Methylcholanthrene 2.8417474063
MESH:D002277 Carcinoma Methylcholanthrene 4.2910545420
MESH:D002280 Carcinoma, Basal Cell Arsenic 3.7817687452 15504454
MESH:D006528 Carcinoma, Hepatocellular 4,4'-diaminodiphenylmethane 3.293581430 7296757
MESH:D006528 Carcinoma, Hepatocellular Arsenic 3.2917306315 16507464
MESH:D002292 Carcinoma, Renal Cell 4,4'-diaminodiphenylmethane 2.837296757
MESH:D002294 Carcinoma, Squamous Cell Arsenic 2.7717687452 18922899 15504454
MESH:D002295 Carcinoma, Transitional Cell Arsenic 4.4718640142
MESH:D002318 Cardiovascular Diseases Arsenic 3.7115738583 19152805 17938729
MESH:D002340 Carotid Artery Diseases Arsenic 4.6818022660 16973168
MESH:D002471 Cell Transformation, Neoplastic 4,4'-diaminodiphenylmethane 7.817505956
MESH:D002471 Cell Transformation, Neoplastic Methylcholanthrene 7.8116192471
MESH:D002779 Cholestasis 4,4'-diaminodiphenylmethane 3.449022650 19486331
MESH:D017449 Dermatitis, Allergic Contact 4,4'-diaminodiphenylmethane 3.358970840 12868966 18759878 11906362 14531868 8156756 2524372 11298694
MESH:D003877 Dermatitis, Contact 4,4'-diaminodiphenylmethane 3.953621924 2952479
MESH:D056486 Drug-Induced Liver Injury 4,4'-diaminodiphenylmethane 2.049022650 18692083 16192314 18289764 6679447 9328219 9653073 11289319 1440618 7440962 8291058 18648102 6482804
MESH:D004938 Esophageal Neoplasms 4,4'-diaminodiphenylmethane 2.183581430
MESH:D005350 Fibroma 4,4'-diaminodiphenylmethane 5.746705139
MESH:D005354 Fibrosarcoma Methylcholanthrene 5.5714633661 10962813
MESH:D005534 Foot Diseases Arsenic 6.286392382
MESH:D006042 Goiter 4,4'-diaminodiphenylmethane 4.507505956
MESH:D006505 Hepatitis 4,4'-diaminodiphenylmethane 4.026705139
MESH:D017488 Hyperkeratosis, Epidermolytic Arsenic 4.8517050553
MESH:D006965 Hyperplasia 4,4'-diaminodiphenylmethane 4.5015034207
MESH:D006973 Hypertension Arsenic 2.9916076760 9931084 11953799
MESH:D006987 Hypesthesia Arsenic 6.2816093927
MESH:D007565 Jaundice 4,4'-diaminodiphenylmethane 5.748074119 9022650
MESH:D007642 Keratosis Arsenic 5.6216930632 12749816
MESH:D007680 Kidney Neoplasms 4,4'-diaminodiphenylmethane 3.316582329
MESH:D015473 Leukemia, Promyelocytic, Acute Arsenic 3.7917339181
MESH:D008105 Liver Cirrhosis, Biliary 4,4'-diaminodiphenylmethane 3.4215034207 9327722
MESH:D008107 Liver Diseases Arsenic 2.6111134558
MESH:D008113 Liver Neoplasms Arsenic 2.7916368122
MESH:D008114 Liver Neoplasms, Experimental 4,4'-diaminodiphenylmethane 6.931399818 598648 3712494 6587162
MESH:D008114 Liver Neoplasms, Experimental Methylcholanthrene 6.93598648 1399818
MESH:D008175 Lung Neoplasms Arsenic 2.9417306315 19168569 17976673
MESH:D008175 Lung Neoplasms Methylcholanthrene 2.9420970405 20512841 16271038 17909032 1399818 6695378 7750092 16337739 15390079 10545420 9230183 11893704 21163286
MESH:D017202 Myocardial Ischemia Arsenic 4.3115371236
MESH:D009362 Neoplasm Metastasis 4,4'-diaminodiphenylmethane 2.593581430
MESH:D009436 Neural Tube Defects 4,4'-diaminodiphenylmethane 8.196679447
MESH:D009436 Neural Tube Defects Arsenic 8.1916620997
MESH:D020078 Neurogenic Inflammation Arsenic 4.8417056641
MESH:D009784 Occupational Diseases 4,4'-diaminodiphenylmethane 3.814026338 6482804
MESH:D009902 Optic Neuritis 4,4'-diaminodiphenylmethane 5.743988306
MESH:D010051 Ovarian Neoplasms Arsenic 2.8417306315
MESH:D010212 Papilloma 4,4'-diaminodiphenylmethane 4.047296757
MESH:D010523 Peripheral Nervous System Diseases Arsenic 4.6816093927
MESH:D016491 Peripheral Vascular Diseases Arsenic 5.6216905509 6392382 15371236
MESH:D010787 Photosensitivity Disorders 4,4'-diaminodiphenylmethane 5.196228378
MESH:D011471 Prostatic Neoplasms Arsenic 3.5516140617
MESH:D011507 Proteinuria Arsenic 4.4721343184
MESH:D012162 Retinal Degeneration 4,4'-diaminodiphenylmethane 3.673692021
MESH:D012871 Skin Diseases Arsenic 2.8219834688 17938729 16353154 15952646 18709164 17050553 17548696 16702368 17453740 16759981 6392382
MESH:D012878 Skin Neoplasms Arsenic 3.1616251483 19538983 17029826 17976673 17050553 15504454
MESH:D013964 Thyroid Neoplasms 4,4'-diaminodiphenylmethane 3.196582329 3712494 1399818 7505956 6587162
MESH:D001749 Urinary Bladder Neoplasms 4,4'-diaminodiphenylmethane 5.638074119
MESH:D001749 Urinary Bladder Neoplasms Arsenic 5.6319322015 17306315 17976673 15987713 11144890 19429237 18640142
MESH:D014652 Vascular Diseases Arsenic 5.3717056641
No data
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Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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