AutismKB 2.0

Annotation Detail for PCDHB4


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:PCDHB4 ( PCDH-BETA4 )
Gene Full Name: protocadherin beta 4
Band: 5q31.3
Quick LinksEntrez ID:56131; OMIM: 606330; Uniprot ID:PCDB4_HUMAN; ENSEMBL ID: ENSG00000081818; HGNC ID: 8689
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
No data
No data
No data
No data
Pathway IDPathway Name
P00012Cadherin signaling pathway
P00057Wnt signaling pathway
No data
Related Diseases/Disorders Top
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
D016572 Cyclosporine Cyclosporine results in decreased expression of PCDHB4 mRNAdecreases expression 20106945
D018038 Sodium Selenite Sodium Selenite results in decreased expression of PCDHB4 mRNAdecreases expression 18175754
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D002471 Cell Transformation, Neoplastic Cyclosporine 2.8512371664
MESH:D002779 Cholestasis Cyclosporine 3.2819486331
MESH:D019457 Chromosome Breakage Sodium Selenite 5.5215894690
MESH:D003920 Diabetes Mellitus Sodium Selenite 4.2516285004
MESH:D056486 Drug-Induced Liver Injury Sodium Selenite 2.3815131321
MESH:D005234 Fatty Liver Cyclosporine 3.4019224547
MESH:D005355 Fibrosis Cyclosporine 3.9012639820 12168785
MESH:D005885 Gingival Hyperplasia Cyclosporine 5.118708960
MESH:D006457 Hemoglobinuria, Paroxysmal Cyclosporine 5.3115720958
MESH:D006973 Hypertension Cyclosporine 2.2410903974
MESH:D007333 Insulin Resistance Sodium Selenite 3.5714714311
MESH:D007638 Keratoconjunctivitis Sicca Cyclosporine 5.5115604871
MESH:D007674 Kidney Diseases Cyclosporine 2.588314463 18776723 10903974
MESH:D007680 Kidney Neoplasms Cyclosporine 3.1712371664
MESH:D016393 Lymphoma, B-Cell Sodium Selenite 4.6614737004
MESH:D008664 Metal Metabolism, Inborn Errors Cyclosporine 5.8616801185
MESH:D009402 Nephrosis, Lipoid Cyclosporine 5.5117954296
MESH:D009404 Nephrotic Syndrome Cyclosporine 3.7518481113 19348381
MESH:D011230 Precancerous Conditions Cyclosporine 3.6912371664
MESH:D011471 Prostatic Neoplasms Sodium Selenite 3.3218760546
MESH:D011565 Psoriasis Cyclosporine 2.3516882103
MESH:D014605 Uveitis Cyclosporine 5.051336536
MESH:D014985 Xerophthalmia Cyclosporine 5.5117120751
No data
Pharmacogenomics Knowledge Base Top
Drug Bank Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


Copyright © 2017, Center for Bioinformatics , Peking University | All Rights Reserved