AutismKB 2.0

Annotation Detail for DNAH7


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Basic Information Top
Gene Symbol:DNAH7 ( DKFZp686C09101,FLJ37196,KIAA0944,MGC39580 )
Gene Full Name: dynein, axonemal, heavy chain 7
Band: 2q32.3
Quick LinksEntrez ID:56171; OMIM: 610061; Uniprot ID:DYH7_HUMAN; ENSEMBL ID: ENSG00000118997; HGNC ID: 18661
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
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Pathway IDPathway Name
P00029Huntington disease
No data
Related Diseases/Disorders Top
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Desease IDDesease Name
1761Respiratory tract disease
2005Bronchial disease
No data
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Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
D000638 Amiodarone Amiodarone results in increased expression of DNAH7 mRNAincreases expression 19774075
D001104 Arbutin Arbutin results in decreased expression of DNAH7 mRNAdecreases expression 17103032
C006632 arsenic trioxide arsenic trioxide results in increased expression of DNAH7 mRNAincreases expression 20458559
D008767 Methylmercury Compounds Methylmercury Compounds results in increased expression of DNAH7 mRNAincreases expression 16966085
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000230 Adenocarcinoma arsenic trioxide 2.3611798837 19825857
MESH:D001145 Arrhythmias, Cardiac Amiodarone 4.2018057881 20041841 18218290
MESH:D001281 Atrial Fibrillation Amiodarone 4.2018651412 19698954
MESH:D001778 Blood Coagulation Disorders Amiodarone 10.7319483382
MESH:D001778 Blood Coagulation Disorders arsenic trioxide 10.7316206674
MESH:D002051 Burkitt Lymphoma arsenic trioxide 4.7911589617
MESH:D006528 Carcinoma, Hepatocellular arsenic trioxide 1.9815073043 16217749 14691202 11135700 15553829
MESH:D002291 Carcinoma, Papillary arsenic trioxide 5.6019014326
MESH:D018288 Carcinoma, Small Cell arsenic trioxide 4.5112490120
MESH:D002311 Cardiomyopathy, Dilated Amiodarone 3.0015710769 19225199
MESH:D002341 Carotid Artery Thrombosis Amiodarone 5.7218974383
MESH:D015179 Colorectal Neoplasms arsenic trioxide 1.8620501625
MESH:D023903 Coronary Restenosis arsenic trioxide 4.6912609071
MESH:D019465 Craniofacial Abnormalities arsenic trioxide 1.8910525206
MESH:D016757 Death, Sudden, Cardiac arsenic trioxide 4.5615213294
MESH:D003704 Dementia Methylmercury Compounds 5.4216140633
MESH:D056486 Drug-Induced Liver Injury Amiodarone 2.4718218290 15265979
MESH:D004938 Esophageal Neoplasms arsenic trioxide 2.3812903497
MESH:D005234 Fatty Liver Amiodarone 9.4414986274
MESH:D005234 Fatty Liver arsenic trioxide 9.4415073043
MESH:D005706 Gallbladder Neoplasms arsenic trioxide 4.7716904648
MESH:D006529 Hepatomegaly Amiodarone 4.3115265979
MESH:D006937 Hypercholesterolemia Amiodarone 4.309751232 8137927
MESH:D007037 Hypothyroidism Amiodarone 5.0817991464 18020914
MESH:D007938 Leukemia arsenic trioxide 3.0015070760
MESH:D015459 Leukemia-Lymphoma, Adult T-Cell arsenic trioxide 4.2217077332 12560223
MESH:D007948 Leukemia, Monocytic, Acute arsenic trioxide 4.9416972261
MESH:D015464 Leukemia, Myelogenous, Chronic, BCR-ABL Positive arsenic trioxide 3.7214633726
MESH:D007951 Leukemia, Myeloid arsenic trioxide 4.1919077051
MESH:D015470 Leukemia, Myeloid, Acute arsenic trioxide 2.1916467208 17050201 20471514 16968895 19850784
MESH:D015473 Leukemia, Promyelocytic, Acute arsenic trioxide 3.4617869043 17217047 17649720 15622746 15213294 15336539 16823087 16330433 11161223 12018890 19225113 12679006 16891316 12712474 16966277 9834237 11468182 19075265 17712046 19642359 19035177 16112521 16331271 17107899 15748426
MESH:D015458 Leukemia, T-Cell arsenic trioxide 4.8616882451
MESH:D008064 Lipidoses Amiodarone 3.7917567588 15342952
MESH:D008113 Liver Neoplasms arsenic trioxide 2.4614682389
MESH:D008114 Liver Neoplasms, Experimental arsenic trioxide 2.9620377131
MESH:D008133 Long QT Syndrome Amiodarone 9.2415350150 17391786 11989578
MESH:D008133 Long QT Syndrome arsenic trioxide 9.2415213294
MESH:D008171 Lung Diseases Amiodarone 3.6212587719
MESH:D017563 Lung Diseases, Interstitial Amiodarone 5.2018516814
MESH:D008175 Lung Neoplasms arsenic trioxide 1.8719825857 11798837
MESH:D008569 Memory Disorders Methylmercury Compounds 5.4118436314
MESH:D009069 Movement Disorders Methylmercury Compounds 5.7918436314
MESH:D009101 Multiple Myeloma arsenic trioxide 3.3814977855 19417148 15949261 11468182 19549372
MESH:D009181 Mycoses Amiodarone 5.6212754197 17974566
MESH:D009182 Mycosis Fungoides arsenic trioxide 5.4018349030
MESH:D009190 Myelodysplastic Syndromes arsenic trioxide 3.3416105982 16882451
MESH:D009361 Neoplasm Invasiveness arsenic trioxide 4.4716624393
MESH:D009436 Neural Tube Defects arsenic trioxide 3.3610525206
MESH:D010051 Ovarian Neoplasms arsenic trioxide 2.5019769630 12452020 16624393
MESH:D010190 Pancreatic Neoplasms arsenic trioxide 2.6315580305
MESH:D010235 Paraganglioma arsenic trioxide 4.6319927285
MESH:D011297 Prenatal Exposure Delayed Effects Methylmercury Compounds 5.6118436314
MESH:D011471 Prostatic Neoplasms arsenic trioxide 3.2119131511
MESH:D011658 Pulmonary Fibrosis Amiodarone 2.9712490602 12832656 11597910
MESH:D012512 Sarcoma, Ewing's arsenic trioxide 4.4716646077
OMIM:609620 SHORT QT SYNDROME 1 Amiodarone 5.7218724381
MESH:D013274 Stomach Neoplasms arsenic trioxide 1.8617007042
MESH:D013276 Stomach Ulcer Amiodarone 3.7418087811
MESH:D013610 Tachycardia Amiodarone 4.8011238279
MESH:D017180 Tachycardia, Ventricular Amiodarone 4.7019225199
MESH:D013959 Thyroid Diseases Amiodarone 5.4819731979
MESH:D013964 Thyroid Neoplasms arsenic trioxide 3.3919014326
MESH:D013971 Thyrotoxicosis Amiodarone 5.4219584973 18020914
MESH:D016171 Torsades de Pointes Amiodarone 12.4611989578 17467628
MESH:D016171 Torsades de Pointes arsenic trioxide 12.4615213294
MESH:D001749 Urinary Bladder Neoplasms arsenic trioxide 2.6011780464 12973940 12845720 20435036
No data
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Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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