AutismKB 2.0

Annotation Detail for PSPN


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Basic Information Top
Gene Symbol:PSPN ( PSP )
Gene Full Name: persephin
Band: 19p13.3
Quick LinksEntrez ID:5623; OMIM: 602921; Uniprot ID:PSPN_HUMAN; ENSEMBL ID: ENSG00000125650; HGNC ID: 9579
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
Related Diseases/Disorders Top
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
D000082 Acetaminophen Acetaminophen affects the expression of PSPN mRNAaffects expression 17562736
D000643 Ammonium Chloride Ammonium Chloride affects the expression of PSPN mRNAaffects expression 16483693
C095105 bexarotene bexarotene results in increased expression of PSPN mRNAincreases expression 16648578
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000138 Acidosis Ammonium Chloride 4.3018287403
MESH:D000799 Angioedema Acetaminophen 4.7110982225
MESH:D001321 Autistic Disorder Acetaminophen 1.3918445737
MESH:D001943 Breast Neoplasms bexarotene 2.9516818667 16344269
MESH:D006528 Carcinoma, Hepatocellular Acetaminophen 1.413084413
MESH:D002289 Carcinoma, Non-Small-Cell Lung bexarotene 3.3416247446
MESH:D002386 Cataract Acetaminophen 2.8110977129
MESH:D056486 Drug-Induced Liver Injury Acetaminophen 1.6811834606 16485898 16227642 16393943 18071297 12153990 2444490 17562736 19164858 11743745 16109766 16781746 15619225 10774834 11421492 11739529 19420014 10663392 16081117 14725611 10915739 12540782 12594235 11461765 19739265 18713872 11287661 19370779 19085960 19416960 15968718 12392966 17522070 11529661 17906064 14550746 12958197 12705907 16177239 19923254 14986274
MESH:D056487 Drug-Induced Liver Injury, Chronic Acetaminophen 4.9619426721
MESH:D005756 Gastritis Acetaminophen 4.5416983495
MESH:D006930 Hyperalgesia Acetaminophen 3.0616870215
MESH:D007674 Kidney Diseases Acetaminophen 2.4215629191 12587719
MESH:D008107 Liver Diseases Acetaminophen 1.7119014921 12969438 11587558 16611625 19460945 19784758 16610002 12587719
MESH:D017114 Liver Failure, Acute Acetaminophen 3.6817185352 16871587
MESH:D008175 Lung Neoplasms bexarotene 2.5317849452
MESH:D016410 Lymphoma, T-Cell, Cutaneous bexarotene 5.8011161223
MESH:D008325 Mammary Neoplasms, Experimental bexarotene 3.6719196722 15591091 19196723
MESH:D008546 Melanoma, Experimental Acetaminophen 4.2219513568
MESH:D009376 Neoplasms, Hormone-Dependent bexarotene 5.6519196722
MESH:D019636 Neurodegenerative Diseases Acetaminophen 3.2618514411
MESH:D010146 Pain Acetaminophen 2.7716870215
MESH:D014581 Urticaria Acetaminophen 3.5010982225
Pathway ID Pathway Name
REACT:18266 Axon guidance
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Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018