AutismKB 2.0

Annotation Detail for YLPM1


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Basic Information Top
Gene Symbol:YLPM1 ( C14orf170,ZAP,ZAP3 )
Gene Full Name: YLP motif containing 1
Band: 14q24.3
Quick LinksEntrez ID:56252; OMIM: NA; Uniprot ID:YLPM1_HUMAN; ENSEMBL ID: ENSG00000119596; HGNC ID: 17798
Relate to Another Database: SFARIGene; denovo-db
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Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C006632 arsenic trioxide arsenic trioxide results in increased expression of YLPM1 mRNAincreases expression 20458559
D015123 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in decreased expression of YLPM1 mRNAdecreases expression 19150397
C006253 pirinixic acid pirinixic acid results in increased expression of YLPM1 mRNAincreases expression 18301758
D012643 Selenium Selenium results in decreased expression of YLPM1 mRNAdecreases expression 19244175
D014810 Vitamin E Vitamin E results in decreased expression of YLPM1 mRNAdecreases expression 19244175
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D055371 Acute Lung Injury pirinixic acid 3.5218653653
MESH:D000230 Adenocarcinoma arsenic trioxide 2.3511798837 19825857
MESH:D018248 Adenoma, Liver Cell pirinixic acid 4.0216434500
MESH:D001778 Blood Coagulation Disorders arsenic trioxide 10.2716206674
MESH:D001778 Blood Coagulation Disorders pirinixic acid 10.2719483382
MESH:D002051 Burkitt Lymphoma arsenic trioxide 4.7311589617
MESH:D002252 Carbon Tetrachloride Poisoning Vitamin E 4.4116050911
MESH:D006528 Carcinoma, Hepatocellular arsenic trioxide 1.9811135700 14691202 16217749 15553829 15073043
MESH:D002291 Carcinoma, Papillary arsenic trioxide 5.4919014326
MESH:D018288 Carcinoma, Small Cell arsenic trioxide 4.4712490120
MESH:D002471 Cell Transformation, Neoplastic 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 2.9620889678
MESH:D002779 Cholestasis pirinixic acid 3.0819176532
MESH:D003092 Colitis Selenium 4.2617936198
MESH:D015179 Colorectal Neoplasms arsenic trioxide 1.8620501625
MESH:D023903 Coronary Restenosis arsenic trioxide 4.6312609071
MESH:D019465 Craniofacial Abnormalities arsenic trioxide 2.7910525206
MESH:D019465 Craniofacial Abnormalities Vitamin E 2.7919769572
MESH:D016757 Death, Sudden, Cardiac arsenic trioxide 4.5015213294
MESH:D003876 Dermatitis, Atopic pirinixic acid 2.5618249437
MESH:D056486 Drug-Induced Liver Injury Selenium 2.2515131321
MESH:C538011 Eales disease Vitamin E 5.329068938
MESH:D004487 Edema pirinixic acid 2.8512083418
MESH:D004938 Esophageal Neoplasms 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 4.7020426865
MESH:D004938 Esophageal Neoplasms arsenic trioxide 4.7012903497
MESH:D005234 Fatty Liver arsenic trioxide 8.9815073043
MESH:D005234 Fatty Liver pirinixic acid 8.9819236843 20131406
MESH:D005706 Gallbladder Neoplasms arsenic trioxide 4.7016904648
MESH:D006330 Heart Defects, Congenital Vitamin E 3.1516080930
MESH:D006333 Heart Failure pirinixic acid 7.6220558911
MESH:D006333 Heart Failure Selenium 7.6217162251
MESH:D006529 Hepatomegaly pirinixic acid 3.4819176532 18467677 16221962 19772884
MESH:D006548 Hernia, Diaphragmatic Vitamin E 2.8016490937 16863852
MESH:D019584 Hot Flashes Vitamin E 4.5814716179
MESH:D006943 Hyperglycemia pirinixic acid 3.5320558911
MESH:D007251 Influenza, Human Selenium 13.0916624496
MESH:D007251 Influenza, Human Vitamin E 13.0916624496
MESH:D007333 Insulin Resistance pirinixic acid 2.8516306350
MESH:D007674 Kidney Diseases Vitamin E 2.9812488133
MESH:D007676 Kidney Failure, Chronic Selenium 4.2616518626
MESH:D007938 Leukemia arsenic trioxide 2.9815070760
MESH:D015459 Leukemia-Lymphoma, Adult T-Cell arsenic trioxide 4.1717077332 12560223
MESH:D007948 Leukemia, Monocytic, Acute arsenic trioxide 4.8516972261
MESH:D015464 Leukemia, Myelogenous, Chronic, BCR-ABL Positive arsenic trioxide 3.6914633726
MESH:D007951 Leukemia, Myeloid arsenic trioxide 4.1319077051
MESH:D015470 Leukemia, Myeloid, Acute arsenic trioxide 2.1816968895 16467208 17050201 19850784 20471514
MESH:D015473 Leukemia, Promyelocytic, Acute arsenic trioxide 3.4317649720 15336539 19075265 19225113 15622746 12018890 16823087 12712474 16891316 17217047 15213294 11468182 12679006 16966277 19035177 16330433 17712046 17107899 17869043 11161223 16112521 19642359 15748426 9834237 16331271
MESH:D015458 Leukemia, T-Cell arsenic trioxide 4.7916882451
MESH:D008106 Liver Cirrhosis, Experimental pirinixic acid 2.4615474484
MESH:D008106 Liver Cirrhosis, Experimental Vitamin E 2.4616169303
MESH:D008113 Liver Neoplasms arsenic trioxide 4.8414682389
MESH:D008113 Liver Neoplasms pirinixic acid 4.8420007298 16377806 15890375
MESH:D008114 Liver Neoplasms, Experimental arsenic trioxide 2.9320377131
MESH:D008133 Long QT Syndrome arsenic trioxide 3.6215213294
MESH:D008171 Lung Diseases Vitamin E 3.4016863852
MESH:D008175 Lung Neoplasms arsenic trioxide 2.6211798837 19825857
MESH:D008175 Lung Neoplasms Vitamin E 2.6211062179
MESH:D008325 Mammary Neoplasms, Experimental Selenium 2.9715318939
MESH:D008654 Mesothelioma Selenium 2.9015107826
MESH:D009101 Multiple Myeloma arsenic trioxide 3.3514977855 15949261 19417148 11468182 19549372
MESH:D009135 Muscular Diseases pirinixic acid 3.9916239165
MESH:D009182 Mycosis Fungoides arsenic trioxide 5.2818349030
MESH:D009190 Myelodysplastic Syndromes arsenic trioxide 3.3216882451 16105982
MESH:D009203 Myocardial Infarction pirinixic acid 2.2619151258
MESH:D015428 Myocardial Reperfusion Injury pirinixic acid 3.2216411023
MESH:D009361 Neoplasm Invasiveness arsenic trioxide 4.4016624393
MESH:D009369 Neoplasms pirinixic acid 2.0917405874
MESH:D009436 Neural Tube Defects arsenic trioxide 3.3310525206
MESH:D009765 Obesity pirinixic acid 1.8820558911
MESH:D010051 Ovarian Neoplasms arsenic trioxide 2.4919769630 16624393 12452020
MESH:D010190 Pancreatic Neoplasms arsenic trioxide 2.6215580305
MESH:D010235 Paraganglioma arsenic trioxide 4.5719927285
MESH:D010954 Plasmacytoma Selenium 5.5015087411
MESH:D011471 Prostatic Neoplasms arsenic trioxide 3.2219131511
MESH:D011471 Prostatic Neoplasms Vitamin E 3.2215084515
MESH:D015427 Reperfusion Injury pirinixic acid 2.5319058328
MESH:D012512 Sarcoma, Ewing's arsenic trioxide 4.4016646077
MESH:D012871 Skin Diseases Vitamin E 2.5118709164
MESH:D013274 Stomach Neoplasms arsenic trioxide 1.8617007042
MESH:D020521 Stroke Vitamin E 3.8116517955
MESH:D013964 Thyroid Neoplasms arsenic trioxide 3.3619014326
MESH:D016171 Torsades de Pointes arsenic trioxide 4.5015213294
MESH:D001749 Urinary Bladder Neoplasms arsenic trioxide 2.5920435036 11780464 12845720 12973940
No data
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AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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