AutismKB 2.0

Annotation Detail for SERTAD4


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Basic Information Top
Gene Symbol:SERTAD4 ( DJ667H12.2 )
Gene Full Name: SERTA domain containing 4
Band: 1q32.2
Quick LinksEntrez ID:56256; OMIM: NA; Uniprot ID:SRTD4_HUMAN; ENSEMBL ID: ENSG00000082497; HGNC ID: 25236
Relate to Another Database: SFARIGene; denovo-db
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Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
D000082 Acetaminophen Acetaminophen affects the expression of SERTAD4 mRNAaffects expression 17562736
D002251 Carbon Tetrachloride Carbon Tetrachloride affects the expression of SERTAD4 mRNAaffects expression 17484886
D004041 Dietary Fats Dietary Fats results in increased expression of SERTAD4 mRNAincreases expression 18042831
C041786 palm oil palm oil results in increased expression of SERTAD4 mRNAincreases expression 18042831
C024746 tobacco tar tobacco tar results in decreased expression of SERTAD4 mRNAdecreases expression 19559774
D019287 Zinc Sulfate Zinc Sulfate results in increased expression of SERTAD4 mRNAincreases expression 16330358
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000138 Acidosis Zinc Sulfate 5.377265320
MESH:D000799 Angioedema Acetaminophen 4.3610982225
MESH:D000860 Anoxia Zinc Sulfate 5.487265320
MESH:D001161 Arteriosclerosis Dietary Fats 4.3115238619
MESH:D001321 Autistic Disorder Acetaminophen 1.4018445737
MESH:D001943 Breast Neoplasms Dietary Fats 2.2520435547
MESH:D002252 Carbon Tetrachloride Poisoning Carbon Tetrachloride 4.2016050911 18705752 15721981 3786805 16192424 16011737 15673190 16097048 16227642 16124888 10355542 15700767
MESH:D006528 Carcinoma, Hepatocellular Acetaminophen 2.963084413
MESH:D006528 Carcinoma, Hepatocellular Carbon Tetrachloride 2.9618788625
MESH:D002386 Cataract Acetaminophen 2.7510977129
MESH:D002471 Cell Transformation, Neoplastic tobacco tar 4.1519559774
MESH:D056486 Drug-Induced Liver Injury Acetaminophen 3.9919923254 19416960 12540782 10915739 12392966 19739265 11834606 14725611 19085960 11287661 16177239 11743745 16485898 16081117 19420014 18071297 2444490 17522070 16393943 11461765 12153990 12705907 19370779 11421492 15619225 16109766 12958197 17906064 16227642 18713872 17562736 15968718 14550746 11739529 10774834 11529661 12594235 10663392 14986274 16781746 19164858
MESH:D056486 Drug-Induced Liver Injury Carbon Tetrachloride 3.9916177239 7179309 19336974 7120509 16227642 15027814 15968718 10915739 9327722 3732212 11566570 6623471 2869522 3786805 7440962 6884620 19085960 10092053 4309450 15998439 17522070 21278145
MESH:D056487 Drug-Induced Liver Injury, Chronic Acetaminophen 4.6219426721
MESH:D050171 Dyslipidemias Dietary Fats 3.6718367378
MESH:D005234 Fatty Liver Carbon Tetrachloride 8.9516045604 12631006 61145 15959796 19224547 16239168 17595544 12795759
MESH:D005234 Fatty Liver Dietary Fats 8.9517967931 18296743 19551842 19004024
MESH:D005355 Fibrosis Carbon Tetrachloride 10.2418705752
MESH:D005355 Fibrosis Dietary Fats 10.2418296743
MESH:D005756 Gastritis Acetaminophen 4.1916983495
MESH:D006505 Hepatitis Carbon Tetrachloride 3.9719900420 19110552
MESH:D006527 Hepatolenticular Degeneration Zinc Sulfate 5.4117063115
MESH:D006930 Hyperalgesia Acetaminophen 2.9516870215
MESH:D006932 Hyperbilirubinemia Carbon Tetrachloride 4.9916899240
MESH:D006937 Hypercholesterolemia Dietary Fats 3.9221332399
MESH:D006949 Hyperlipidemias Dietary Fats 3.9721332399
MESH:D006975 Hypertension, Portal Carbon Tetrachloride 4.5015338365
MESH:D007022 Hypotension Zinc Sulfate 4.827265320
MESH:D007249 Inflammation Dietary Fats 2.5720412841
MESH:D007333 Insulin Resistance Dietary Fats 3.3011836018 18457598
MESH:D007674 Kidney Diseases Acetaminophen 2.3612587719 15629191
MESH:D016773 Leishmaniasis, Cutaneous Zinc Sulfate 4.5315237267
MESH:D008103 Liver Cirrhosis Carbon Tetrachloride 7.1511408273 16943688 16239168 17157831 21278145 11903743 17174718 16221502 17334410
MESH:D008103 Liver Cirrhosis Dietary Fats 7.1518296743
MESH:D008106 Liver Cirrhosis, Experimental Carbon Tetrachloride 1.7517823541 17976157 12609069 12632514 18006644 17805973 14716833 18210741 18251166 17944888 16015684 15959796 18277467 18317297 14512876 17525996 12389079 17766677 17761835 18339082 16097048 17640975 20821823 15057751 15818738 18705752 18054572 15123356 18472332 16116963 17481882 15876570 14724832 15052691 18395095 17631135 15370692 15673190 15925388 12632512 15931870 18279442 17869086 17708605 11481614 16192424 16136751 16011737 12649538 13678700 16033810 18187930 17714472 12445421 18420326 16248980 14716496 18156304 12445418 15362042 14748882 18481824 17922224 18166357 14620537 16027843 17900296 17557913 17698563 15338365 18472094 12741479 12666154 17721639 18376398 18412020 16638106 18263696 12586293 12667390 15650968 12898905 18429990 18395914 15893842 12546737 10355542 18205269 12958196 15996030 18418968 17565644 15730626
MESH:D008107 Liver Diseases Acetaminophen 4.1212969438 19014921 16611625 19460945 19784758 12587719 11587558 16610002
MESH:D008107 Liver Diseases Carbon Tetrachloride 4.1215720792 16964402 16246199 17285989 15830285
MESH:D017093 Liver Failure Carbon Tetrachloride 4.5815123358
MESH:D017114 Liver Failure, Acute Acetaminophen 10.4416871587 17185352
MESH:D017114 Liver Failure, Acute Carbon Tetrachloride 10.4414706259 16899240
MESH:D008113 Liver Neoplasms Carbon Tetrachloride 2.3119294768
MESH:D008114 Liver Neoplasms, Experimental Carbon Tetrachloride 2.7912014681 15583823
MESH:D008546 Melanoma, Experimental Acetaminophen 3.9819513568
MESH:D019636 Neurodegenerative Diseases Acetaminophen 3.1418514411
MESH:D009765 Obesity Dietary Fats 2.3420132043 18674790 11836018 21332399 20518802 18457598 16723640 19632207 17217161
MESH:D010146 Pain Acetaminophen 2.6516870215
MESH:D014581 Urticaria Acetaminophen 3.3310982225
MESH:D015430 Weight Gain Dietary Fats 4.0216723640
No data
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AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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