AutismKB 2.0

Annotation Detail for AZGP1


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Basic Information Top
Gene Symbol:AZGP1 ( ZA2G,ZAG )
Gene Full Name: alpha-2-glycoprotein 1, zinc-binding
Band: 7q22.1
Quick LinksEntrez ID:563; OMIM: 194460; Uniprot ID:ZA2G_HUMAN; ENSEMBL ID: ENSG00000160862; HGNC ID: 910
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
Related Diseases/Disorders Top
No data
Desease IDDesease Name
1831Prostate cancer
1856Obesity
2066Lung cancer
No data
No data
No data
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C403065 10-(fluoroethoxyphosphinyl)-N-(biotinamidopentyl)decanamide 10-(fluoroethoxyphosphinyl)-N-(biotinamidopentyl)decanamide binds to AZGP1 proteinaffects binding 19539807
C063002 2,3-dimethoxy-1,4-naphthoquinone 2,3-dimethoxy-1,4-naphthoquinone results in decreased expression of AZGP1 mRNAdecreases expression 17547211
D000082 Acetaminophen Acetaminophen affects the expression of AZGP1 mRNAaffects expression 17562736
D016604 Aflatoxin B1 Aflatoxin B1 affects the expression of AZGP1 proteinaffects expression 20106945
D000643 Ammonium Chloride Ammonium Chloride affects the expression of AZGP1 mRNAaffects expression 16483693
D000965 Antimony Antimony results in decreased expression of AZGP1 mRNAdecreases expression 17547211
D000966 Antimony Potassium Tartrate Antimony Potassium Tartrate results in decreased expression of AZGP1 mRNAdecreases expression 17547211
C006632 arsenic trioxide arsenic trioxide results in decreased expression of AZGP1 mRNAdecreases expression 17547211
D002857 Chromium Chromium results in decreased expression of AZGP1 mRNAdecreases expression 17547211
C030123 coumarin coumarin affects the expression of AZGP1 mRNAaffects expression 16963487
D016572 Cyclosporine Cyclosporine results in decreased expression of AZGP1 mRNAdecreases expression 20106945
C014347 decitabine decitabine inhibits the reaction [trichostatin A results in increased expression of AZGP1 mRNA]decreases reaction|increases expression 18978557
D004052 Diethylnitrosamine Diethylnitrosamine results in decreased expression of AZGP1 mRNAdecreases expression 19638242
D004317 Doxorubicin Doxorubicin results in decreased expression of AZGP1 mRNAdecreases expression 16404146
D000431 Ethanol Ethanol results in increased expression of AZGP1 mRNAincreases expression 15353170
D004997 Ethinyl Estradiol Ethinyl Estradiol results in increased expression of AZGP1 mRNAincreases expression 17942748
D004997 Ethinyl Estradiol [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of AZGP1 mRNAaffects cotreatment|increases expression 17942748
D005419 Flavonoids Flavonoids results in decreased expression of AZGP1 mRNAdecreases expression 18035473
D017258 Medroxyprogesterone Acetate Medroxyprogesterone Acetate results in increased expression of AZGP1 mRNAincreases expression 15866426
D008628 Mercury Mercury results in decreased expression of AZGP1 mRNAdecreases expression 17547211
D011192 Potassium Dichromate Potassium Dichromate results in decreased expression of AZGP1 mRNAdecreases expression 17547211
D013739 Testosterone Testosterone affects the expression of AZGP1 mRNAaffects expression 17003280
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in increased expression of AZGP1 mRNAincreases expression 20106945
D013749 Tetrachlorodibenzodioxin [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of AZGP1 mRNAaffects cotreatment|increases expression 17942748
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in decreased expression of AZGP1 mRNAdecreases expression 18796159
C012589 trichostatin A decitabine inhibits the reaction [trichostatin A results in increased expression of AZGP1 mRNA]decreases reaction|increases expression 18978557
C012589 trichostatin A trichostatin A results in increased expression of AZGP1 mRNAincreases expression 18978557
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000014 Abnormalities, Drug-Induced Ethanol 7.9618926900 17676605
MESH:D000014 Abnormalities, Drug-Induced Tetrachlorodibenzodioxin 7.9614514962 15322242 11752688
MESH:D000138 Acidosis Ammonium Chloride 9.9618287403
MESH:D000138 Acidosis Ethanol 9.9611192467
MESH:D000152 Acne Vulgaris Ethinyl Estradiol 3.7917505938
MESH:D000230 Adenocarcinoma marker/mechanism 18978557
MESH:D000230 Adenocarcinoma arsenic trioxide 6.8811798837 19825857
MESH:D000230 Adenocarcinoma Doxorubicin 6.8817418594
MESH:D000230 Adenocarcinoma Ethinyl Estradiol 6.8814692618
MESH:D000236 Adenoma Diethylnitrosamine 2.7610737359 6695378
MESH:D018248 Adenoma, Liver Cell Diethylnitrosamine 9.5519052882 19061943 18056438 16434500 17620307 17162532
MESH:D018248 Adenoma, Liver Cell Tetrachlorodibenzodioxin 9.5516835633
MESH:D000419 Albuminuria Doxorubicin 4.4021441931
MESH:D020268 Alcohol-Induced Disorders, Nervous System Ethanol 5.1715451039 15451040
MESH:D000740 Anemia Tetrachlorodibenzodioxin 2.8111748828
MESH:D000799 Angioedema Acetaminophen 3.6910982225
MESH:D000853 Anophthalmos Ethanol 4.6715513904
MESH:D000987 Antisocial Personality Disorder Testosterone 5.707506515
MESH:D001008 Anxiety Disorders Ethanol 3.8811141031
MESH:D001161 Arteriosclerosis Ethinyl Estradiol 3.3111256880
MESH:D001169 Arthritis, Experimental Ethinyl Estradiol 2.5715885639
MESH:D001321 Autistic Disorder Acetaminophen 2.1418445737
MESH:D001321 Autistic Disorder Mercury 2.1417497416
MESH:D001327 Autoimmune Diseases Mercury 4.7216634805
MESH:D001778 Blood Coagulation Disorders arsenic trioxide 8.5016206674
MESH:D001778 Blood Coagulation Disorders Tetrachlorodibenzodioxin 8.5012125929
MESH:D001836 Body Weight Changes Tetrachlorodibenzodioxin 3.6415340226
MESH:D001848 Bone Diseases, Developmental Tetrachlorodibenzodioxin 2.6715746008
MESH:D019046 Bone Marrow Neoplasms Doxorubicin 4.5514601052
MESH:D001932 Brain Neoplasms Doxorubicin 3.6817150277
MESH:D001943 Breast Neoplasms Chromium 2.9015986119
MESH:D001943 Breast Neoplasms decitabine 2.9019208741 18320071
MESH:D001943 Breast Neoplasms Diethylnitrosamine 2.9017474063
MESH:D001943 Breast Neoplasms Doxorubicin 2.9015993339 18695136 18628466 16264153 11325840 18382427 16115903 16935488 15692762 15994142 16096432 15634643 17369602 16595493 18234424 15567936 17983394 16322301 15668708 17426702 16826403 19526202 15939500 15136595
MESH:D001943 Breast Neoplasms Testosterone 2.9017261762
MESH:D001943 Breast Neoplasms Tetrachlorodibenzodioxin 2.9020435547
MESH:D001991 Bronchitis Antimony 5.988768112
MESH:D002051 Burkitt Lymphoma arsenic trioxide 4.1911589617
MESH:D002056 Burns Ethanol 4.5016374292
MESH:D002276 Carcinoid Tumor Doxorubicin 4.6616051944
MESH:D002277 Carcinoma Tetrachlorodibenzodioxin 2.6816835633
MESH:D006528 Carcinoma, Hepatocellular Acetaminophen 11.073084413
MESH:D006528 Carcinoma, Hepatocellular Aflatoxin B1 11.0721507988 12907637 12619106
MESH:D006528 Carcinoma, Hepatocellular arsenic trioxide 11.0715073043 14691202 11135700 15553829 16217749
MESH:D006528 Carcinoma, Hepatocellular Diethylnitrosamine 11.0718393292 16540662 19519916 19383236 17428255 20214788 19335982 19418558 19052882 20727157 20007298 18691550 19701751 19107877 18785209 18971187 20084675 17162532 20524982 16779866 20935162 18978308 3084413 19208518 3581430 18056438 19394651 10737359 16807293 20512989 18210153 18494052 19539802 20432363 17978847 11831363 17055752 16569478 19171122 21159647 17138121 19822196 20514400 20101231 10672840 16830150 16328049 16681979 16288022 16502159 17173139 18665156 16878318 16698587 18506893 16935385 17761372 18788625 19919837
MESH:D006528 Carcinoma, Hepatocellular Doxorubicin 11.0716023760 16234567 18059187 17876044
MESH:D006528 Carcinoma, Hepatocellular Ethanol 11.0715289165 15763234 18788625
MESH:D002291 Carcinoma, Papillary arsenic trioxide 4.7219014326
MESH:D002292 Carcinoma, Renal Cell Doxorubicin 3.091485588 16201981
MESH:D018288 Carcinoma, Small Cell arsenic trioxide 3.9812490120
MESH:D002294 Carcinoma, Squamous Cell decitabine 4.7519215824
MESH:D002294 Carcinoma, Squamous Cell Doxorubicin 4.756189445
MESH:D006332 Cardiomegaly Ethanol 6.5719332462
MESH:D006332 Cardiomegaly Tetrachlorodibenzodioxin 6.5716120746 18850075 18670907
MESH:D009202 Cardiomyopathies Doxorubicin 3.4315811867 17308081 16952015 17519947 17131338 16612575 16269455 17007740 16731534 15476868 17329180 17974986 16651473 17924179 16278810 16242529 17351982 17382496 15792986 16455267 16364871 18627295 15505089 16109756 17928571
MESH:D002311 Cardiomyopathy, Dilated Antimony 9.4910334427
MESH:D002311 Cardiomyopathy, Dilated Doxorubicin 9.4916243910 17334414
MESH:D002311 Cardiomyopathy, Dilated Mercury 9.4910334427
MESH:D002386 Cataract Acetaminophen 2.4910977129
MESH:D002471 Cell Transformation, Neoplastic Cyclosporine 6.2612371664
MESH:D002471 Cell Transformation, Neoplastic Diethylnitrosamine 6.267505956 21159647 17174075 2727394
MESH:D002659 Child Development Disorders, Pervasive Testosterone 3.6220678186
MESH:D018281 Cholangiocarcinoma Diethylnitrosamine 8.8919052882
MESH:D018281 Cholangiocarcinoma Tetrachlorodibenzodioxin 8.8916835633
MESH:D002779 Cholestasis Cyclosporine 7.4019486331
MESH:D002779 Cholestasis Ethinyl Estradiol 7.4017333356 16105132 17110522 17681005 15861022 11677210 16919318
MESH:D002971 Cleft Lip Ethanol 3.5115513904
MESH:D002972 Cleft Palate Ethanol 5.7415513904
MESH:D002972 Cleft Palate Tetrachlorodibenzodioxin 5.7415668235 8697196 16354765 15340226 12621046
MESH:D003110 Colonic Neoplasms decitabine 2.3117616700
MESH:D015179 Colorectal Neoplasms arsenic trioxide 3.4120501625
MESH:D015179 Colorectal Neoplasms decitabine 3.4118981723
MESH:D015179 Colorectal Neoplasms Doxorubicin 3.4118259882 18802399
MESH:D000013 Congenital Abnormalities Tetrachlorodibenzodioxin 2.9317141729 14669216
MESH:D023903 Coronary Restenosis arsenic trioxide 4.0412609071
MESH:D019465 Craniofacial Abnormalities arsenic trioxide 3.7310525206
MESH:D019465 Craniofacial Abnormalities Ethanol 3.7310194807 19302082 15451040 11198716 11873399 15451039 15513904
MESH:D019465 Craniofacial Abnormalities Tetrachlorodibenzodioxin 3.7320055451 15322242 10048152
MESH:D016757 Death, Sudden, Cardiac arsenic trioxide 3.9515213294
MESH:D017449 Dermatitis, Allergic Contact Mercury 7.2416823706
MESH:D017449 Dermatitis, Allergic Contact Potassium Dichromate 7.2416823706
MESH:D003924 Diabetes Mellitus, Type 2 coumarin 6.9819647726
MESH:D003924 Diabetes Mellitus, Type 2 Diethylnitrosamine 6.9820387270
MESH:D003924 Diabetes Mellitus, Type 2 Tetrachlorodibenzodioxin 6.9817107852
MESH:D004283 Dog Diseases Antimony 5.5012019027
MESH:D056486 Drug-Induced Liver Injury Acetaminophen 11.5317906064 19085960 14550746 11421492 14986274 16393943 19739265 16109766 12958197 2444490 11287661 16177239 10915739 16081117 12540782 15968718 11461765 17522070 11834606 16485898 12705907 17562736 18071297 19923254 10663392 19370779 12153990 12594235 11529661 10774834 16781746 11739529 19416960 11743745 16227642 18713872 14725611 19420014 12392966 15619225 19164858
MESH:D056486 Drug-Induced Liver Injury Diethylnitrosamine 11.5319107877
MESH:D056486 Drug-Induced Liver Injury Doxorubicin 11.5317416283
MESH:D056486 Drug-Induced Liver Injury Ethanol 11.5311566570
MESH:D056486 Drug-Induced Liver Injury Tetrachlorodibenzodioxin 11.5320420201
MESH:D056487 Drug-Induced Liver Injury, Chronic Acetaminophen 3.9519426721
MESH:D004362 Drug Toxicity Doxorubicin 7.7418602426
MESH:D004362 Drug Toxicity Tetrachlorodibenzodioxin 7.7411462148
MESH:D004487 Edema Tetrachlorodibenzodioxin 2.2412711302 11000095
MESH:D004489 Edema, Cardiac Tetrachlorodibenzodioxin 3.7518230668 15322242 16714409
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Ethinyl Estradiol 3.0412538720
MESH:D004701 Endocrine Gland Neoplasms decitabine 13.5219294695
MESH:D004701 Endocrine Gland Neoplasms trichostatin A 13.5219294695
MESH:D016889 Endometrial Neoplasms Doxorubicin 3.3517359293
MESH:D004715 Endometriosis Tetrachlorodibenzodioxin 2.899294722 10568697
MESH:D004719 Endomyocardial Fibrosis Doxorubicin 5.0118037988
MESH:D004931 Esophageal Achalasia Diethylnitrosamine 4.9716302075
MESH:D004938 Esophageal Neoplasms arsenic trioxide 4.5812903497
MESH:D004938 Esophageal Neoplasms Ethanol 4.5816704527
MESH:D005124 Eye Abnormalities Tetrachlorodibenzodioxin 2.9011564622
MESH:D005234 Fatty Liver arsenic trioxide 23.1815073043
MESH:D005234 Fatty Liver Cyclosporine 23.1819224547
MESH:D005234 Fatty Liver Diethylnitrosamine 23.1820387270 21071580
MESH:D005234 Fatty Liver Ethanol 23.1816409862 18620774 19236843
MESH:D005234 Fatty Liver Ethinyl Estradiol 23.1815345470
MESH:D005235 Fatty Liver, Alcoholic Ethanol 5.5117920746
MESH:D005310 Fetal Alcohol Syndrome Ethanol 5.1516946407 15513904 10194807 15451040
MESH:D005313 Fetal Death Tetrachlorodibenzodioxin 3.3111858732
MESH:D018222 Fibromatosis, Aggressive Doxorubicin 4.4419069698
MESH:D005355 Fibrosis Cyclosporine 7.9812639820 12168785
MESH:D005355 Fibrosis Tetrachlorodibenzodioxin 7.9820067830
MESH:D005391 Firesetting Behavior Testosterone 5.707506515
MESH:D005706 Gallbladder Neoplasms arsenic trioxide 4.1116904648
MESH:D005756 Gastritis Acetaminophen 10.6216983495
MESH:D005756 Gastritis Ethanol 10.6215046732
MESH:D005885 Gingival Hyperplasia Cyclosporine 4.078708960
MESH:D005909 Glioblastoma Doxorubicin 11.5817150277
MESH:D005909 Glioblastoma Testosterone 11.5817162496
MESH:D005909 Glioblastoma trichostatin A 11.5818801729
MESH:D006058 Gonadal Disorders Tetrachlorodibenzodioxin 4.4410696789
MESH:D006258 Head and Neck Neoplasms decitabine 7.6219215824
MESH:D006258 Head and Neck Neoplasms Doxorubicin 7.6215692506
MESH:D006330 Heart Defects, Congenital Tetrachlorodibenzodioxin 2.2511294989 10048152
MESH:D006331 Heart Diseases Doxorubicin 3.3816144979 16244372 16330681 18006777 18674790 16879835 16244371 16495754 12587719 14766674 16707910 17875725 17888722
MESH:D006333 Heart Failure Doxorubicin 3.2517481944
MESH:D006394 Hemangiosarcoma Doxorubicin 3.7615692506
MESH:D006457 Hemoglobinuria, Paroxysmal Cyclosporine 4.2715720958
MESH:D006470 Hemorrhage Tetrachlorodibenzodioxin 3.2011000095
MESH:D006529 Hepatomegaly Tetrachlorodibenzodioxin 2.7416120746 12621046 15340226
MESH:D006628 Hirsutism Testosterone 5.5017019078
MESH:D006689 Hodgkin Disease Doxorubicin 3.2817606976 18501091 15147373
MESH:D006869 Hydronephrosis Tetrachlorodibenzodioxin 3.8916354765 15340226 16959395 18606429 8697196
MESH:D006930 Hyperalgesia Acetaminophen 7.4116870215
MESH:D006930 Hyperalgesia Ethanol 7.4118783367
MESH:D017588 Hyperandrogenism Testosterone 5.1617019078
MESH:D006973 Hypertension Cyclosporine 4.7510903974
MESH:D006973 Hypertension Tetrachlorodibenzodioxin 4.7518670907 18850075
MESH:D007006 Hypogonadism Testosterone 4.4812002444
MESH:D007018 Hypopituitarism Testosterone 6.0517426086
MESH:D007021 Hypospadias Ethinyl Estradiol 3.6616945680 16569931
MESH:D007174 Impulse Control Disorders Testosterone 5.707506515
MESH:D007247 Infertility, Female Ethinyl Estradiol 3.3212013081
MESH:D007248 Infertility, Male decitabine 6.3917581917
MESH:D007248 Infertility, Male Ethinyl Estradiol 6.3917937319
MESH:D007249 Inflammation Diethylnitrosamine 7.8518785209
MESH:D007249 Inflammation Flavonoids 7.8517296493
MESH:D007249 Inflammation Tetrachlorodibenzodioxin 7.8512200463 12878042
MESH:D007569 Jaw Abnormalities Ethanol 9.6615513904
MESH:D007569 Jaw Abnormalities Tetrachlorodibenzodioxin 9.6616580747
MESH:D007638 Keratoconjunctivitis Sicca Cyclosporine 4.2915604871
MESH:D007674 Kidney Diseases Acetaminophen 22.7615629191 12587719
MESH:D007674 Kidney Diseases Chromium 22.7617934191
MESH:D007674 Kidney Diseases Cyclosporine 22.7610903974 8314463 18776723
MESH:D007674 Kidney Diseases Doxorubicin 22.7616775033 15699352 15369732
MESH:D007674 Kidney Diseases Mercury 22.7617934191
MESH:D007674 Kidney Diseases Potassium Dichromate 22.7619665454
MESH:D007676 Kidney Failure, Chronic Doxorubicin 4.0116707910
MESH:D007680 Kidney Neoplasms Cyclosporine 2.6112371664
MESH:D007859 Learning Disorders Ethanol 4.0615451040
MESH:D007896 Leishmaniasis Antimony 4.6810953559 21063981 15220340 12019027 21182181
MESH:D016773 Leishmaniasis, Cutaneous Antimony 4.5419141829 8889330 11475954
MESH:D007897 Leishmaniasis, Mucocutaneous Antimony 5.3410651420 7854095 9643325 11370249 10881086
MESH:D007898 Leishmaniasis, Visceral Antimony 8.357875148 7554475 20495762 7854095 8142506 11105143 1899875
MESH:D007898 Leishmaniasis, Visceral Antimony Potassium Tartrate 8.3512707265
MESH:D007938 Leukemia arsenic trioxide 6.2015070760
MESH:D007938 Leukemia decitabine 6.2018980019 19235587
MESH:D004915 Leukemia, Erythroblastic, Acute Doxorubicin 5.0116085563
MESH:D015459 Leukemia-Lymphoma, Adult T-Cell arsenic trioxide 3.6617077332 12560223
MESH:D007948 Leukemia, Monocytic, Acute arsenic trioxide 4.1516972261
MESH:D015464 Leukemia, Myelogenous, Chronic, BCR-ABL Positive arsenic trioxide 3.3214633726
MESH:D007951 Leukemia, Myeloid arsenic trioxide 9.1219077051
MESH:D007951 Leukemia, Myeloid decitabine 9.1218454857 19117987 17236224
MESH:D015470 Leukemia, Myeloid, Acute arsenic trioxide 6.0917050201 19850784 16968895 16467208 20471514
MESH:D015470 Leukemia, Myeloid, Acute decitabine 6.0918460780 17679729 18704418 19387464 18206229 19010910
MESH:D015470 Leukemia, Myeloid, Acute trichostatin A 6.0918206229
MESH:D015477 Leukemia, Myelomonocytic, Chronic decitabine 5.3118055864
MESH:D015473 Leukemia, Promyelocytic, Acute Antimony Potassium Tartrate 7.819834237
MESH:D015473 Leukemia, Promyelocytic, Acute arsenic trioxide 7.8112679006 12018890 17217047 15336539 15622746 12712474 17869043 15748426 16330433 17712046 19642359 16112521 16891316 16331271 16823087 9834237 11161223 17107899 19035177 11468182 17649720 16966277 19225113 15213294 19075265
MESH:D015458 Leukemia, T-Cell arsenic trioxide 4.2016882451
MESH:D017880 Limb Deformities, Congenital Ethanol 3.7117676605
MESH:D008103 Liver Cirrhosis Diethylnitrosamine 6.5420032147 18522880 18407596 18665156 19638242
MESH:D008103 Liver Cirrhosis Ethanol 6.5415289165
MESH:D008104 Liver Cirrhosis, Alcoholic Ethanol 4.9418295389
MESH:D008106 Liver Cirrhosis, Experimental Doxorubicin 3.4716439617 16595196
MESH:D008106 Liver Cirrhosis, Experimental Ethanol 3.4718166357
MESH:D008106 Liver Cirrhosis, Experimental Tetrachlorodibenzodioxin 3.4712878042
MESH:D008107 Liver Diseases Acetaminophen 3.7712969438 11587558 19460945 16610002 19014921 12587719 19784758 16611625
MESH:D008107 Liver Diseases Diethylnitrosamine 3.7717034775
MESH:D008108 Liver Diseases, Alcoholic Ethanol 4.5017207112 17347304
MESH:D017114 Liver Failure, Acute Acetaminophen 3.1016871587 17185352
MESH:D008113 Liver Neoplasms Aflatoxin B1 10.239163691 15890375 2125692 18177683
MESH:D008113 Liver Neoplasms arsenic trioxide 10.2314682389
MESH:D008113 Liver Neoplasms Diethylnitrosamine 10.2319690152 19073162 12771043 19850985 19638242 2862719 20137499 19255062 19499222 19090486 21278145 20583210 19812893 18978307 20452335 19254457 12112319 21071580 20405173 20501860 20492335 15175105 18754104 19294768 18644402 19996281 19256749 18648771 19427195 2422723 9163691 15885732 21047994 20101389 16942905 20118626 10737359 19642983 19833225 19551842 19426721 21167192 18977376 20434301
MESH:D008113 Liver Neoplasms Tetrachlorodibenzodioxin 10.2316984957
MESH:D008114 Liver Neoplasms, Experimental Aflatoxin B1 17.658603461
MESH:D008114 Liver Neoplasms, Experimental arsenic trioxide 17.6520377131
MESH:D008114 Liver Neoplasms, Experimental Diethylnitrosamine 17.6518282651 18079962 19004024 18775883 16842330 19539802 17854601 16267830 21159647 18544905 19519916 19009564 17174075 18253720 2563599 18164116 9362446 17942915 18308698 3124819 19126423 18093689
MESH:D008114 Liver Neoplasms, Experimental Doxorubicin 17.6516842330 17085340
MESH:D008114 Liver Neoplasms, Experimental Tetrachlorodibenzodioxin 17.6512151625
MESH:D008133 Long QT Syndrome arsenic trioxide 3.2315213294
MESH:D008175 Lung Neoplasms marker/mechanism 18978557
MESH:D008175 Lung Neoplasms Aflatoxin B1 6.3914755239
MESH:D008175 Lung Neoplasms arsenic trioxide 6.3919825857 11798837
MESH:D008175 Lung Neoplasms Diethylnitrosamine 6.3920970405 21163286 20512841 6695378
MESH:D008175 Lung Neoplasms Doxorubicin 6.3917418594 6189445
MESH:D008175 Lung Neoplasms Tetrachlorodibenzodioxin 6.3919555203 11884234
MESH:D008223 Lymphoma decitabine 7.3719470736
MESH:D008223 Lymphoma Doxorubicin 7.3716098063
MESH:D008228 Lymphoma, Non-Hodgkin Doxorubicin 3.6717654614
MESH:D016399 Lymphoma, T-Cell Doxorubicin 4.4215621674
MESH:D008325 Mammary Neoplasms, Experimental Doxorubicin 2.9415458769
MESH:D008545 Melanoma decitabine 5.1316505122 17785578
MESH:D008545 Melanoma Doxorubicin 5.1316827129
MESH:D008545 Melanoma trichostatin A 5.1316505122
MESH:D008546 Melanoma, Experimental Acetaminophen 3.4219513568
MESH:D008569 Memory Disorders Ethanol 4.0418411066 15451040
MESH:D008654 Mesothelioma Doxorubicin 3.0017638057
MESH:D008664 Metal Metabolism, Inborn Errors Cyclosporine 4.6416801185
MESH:D028361 Mitochondrial Diseases Doxorubicin 4.3615792986
MESH:D052016 Mucositis Doxorubicin 4.6417415656
MESH:D009101 Multiple Myeloma arsenic trioxide 11.6115949261 19417148 11468182 14977855 19549372
MESH:D009101 Multiple Myeloma decitabine 11.6118172295
MESH:D009101 Multiple Myeloma trichostatin A 11.6118172295
MESH:D009182 Mycosis Fungoides arsenic trioxide 4.5218349030
MESH:D009190 Myelodysplastic Syndromes arsenic trioxide 7.2216105982 16882451
MESH:D009190 Myelodysplastic Syndromes decitabine 7.2219010910 16882708 18608210 19157545
MESH:D009203 Myocardial Infarction Doxorubicin 2.8919429709 15857846
MESH:D017202 Myocardial Ischemia Tetrachlorodibenzodioxin 2.9012213967
MESH:D009361 Neoplasm Invasiveness arsenic trioxide 3.8116624393
MESH:D009362 Neoplasm Metastasis Diethylnitrosamine 5.683581430 9029167
MESH:D009362 Neoplasm Metastasis Doxorubicin 5.6818259882
MESH:D009369 Neoplasms decitabine 2.6419470736 17925555 19116145
MESH:D009401 Nephrosis Doxorubicin 4.6216636307 16899518
MESH:D009402 Nephrosis, Lipoid Cyclosporine 4.2917954296
MESH:D009404 Nephrotic Syndrome Cyclosporine 8.8718481113 19348381
MESH:D009404 Nephrotic Syndrome Doxorubicin 8.8715640375 16889571
MESH:D009421 Nervous System Malformations Tetrachlorodibenzodioxin 3.0714600291
MESH:D009436 Neural Tube Defects arsenic trioxide 3.0210525206
MESH:D009447 Neuroblastoma Doxorubicin 3.1915555623
MESH:D019636 Neurodegenerative Diseases Acetaminophen 7.7718514411
MESH:D019636 Neurodegenerative Diseases Diethylnitrosamine 7.7720387270
MESH:D009461 Neurologic Manifestations Diethylnitrosamine 4.9720387270
MESH:D012516 Osteosarcoma Doxorubicin 3.9915930896
MESH:D010051 Ovarian Neoplasms arsenic trioxide 11.0316624393 12452020 19769630
MESH:D010051 Ovarian Neoplasms decitabine 11.0319331143 19259094
MESH:D010051 Ovarian Neoplasms Medroxyprogesterone Acetate 11.0317393432
MESH:D010051 Ovarian Neoplasms trichostatin A 11.0319331143
MESH:D010146 Pain Acetaminophen 2.2716870215
MESH:D010190 Pancreatic Neoplasms arsenic trioxide 15.7615580305
MESH:D010190 Pancreatic Neoplasms decitabine 15.7619294695
MESH:D010190 Pancreatic Neoplasms Diethylnitrosamine 15.7616540662
MESH:D010190 Pancreatic Neoplasms Ethanol 15.7612384795
MESH:D010190 Pancreatic Neoplasms trichostatin A 15.7619294695
MESH:D016584 Panic Disorder Ethinyl Estradiol 3.5411578682
MESH:D010235 Paraganglioma arsenic trioxide 4.0219927285
MESH:D010382 Peliosis Hepatis Tetrachlorodibenzodioxin 4.1012520081
MESH:D010409 Penile Diseases Antimony 5.579643325
MESH:D010493 Pericarditis Antimony 5.9620465667
MESH:D003557 Phyllodes Tumor Doxorubicin 5.0117983394
MESH:D010997 Pleural Neoplasms Doxorubicin 5.0117638057
MESH:D017119 Porphyria Cutanea Tarda Tetrachlorodibenzodioxin 3.4118163543
MESH:D011230 Precancerous Conditions Cyclosporine 8.5112371664
MESH:D011230 Precancerous Conditions Diethylnitrosamine 8.512563599
MESH:D011297 Prenatal Exposure Delayed Effects Tetrachlorodibenzodioxin 3.0411399792 11896295 11222880 11118676
MESH:D055728 Primary Myelofibrosis decitabine 11.9217616702
MESH:D055728 Primary Myelofibrosis trichostatin A 11.9217616702
MESH:D019048 Prostatic Intraepithelial Neoplasia Testosterone 4.9120887781
MESH:D011471 Prostatic Neoplasms marker/mechanism 17173048
MESH:D011471 Prostatic Neoplasms arsenic trioxide 2.7719131511
MESH:D011471 Prostatic Neoplasms Doxorubicin 2.7716868541 18437689 15897917 15749863 16729912 16888761
MESH:D011471 Prostatic Neoplasms trichostatin A 2.7718798265 19789329
MESH:D011537 Pruritus Ethinyl Estradiol 3.1616919318 15861022
MESH:D011565 Psoriasis Cyclosporine 2.1816882103
MESH:D051437 Renal Insufficiency Doxorubicin 4.0717922066
MESH:D015619 Respiratory System Abnormalities Tetrachlorodibenzodioxin 3.6918990726
MESH:D012208 Rhabdomyosarcoma decitabine 4.2619155313
MESH:D012509 Sarcoma Doxorubicin 3.8616767912 17203757 15675481 17710206 18313854 15625365
MESH:D012512 Sarcoma, Ewing's arsenic trioxide 9.7916646077
MESH:D012512 Sarcoma, Ewing's Doxorubicin 9.7916326096 14601052
MESH:D012514 Sarcoma, Kaposi Doxorubicin 4.6417846226
MESH:D012640 Seizures Ethanol 3.079754883
MESH:D012735 Sexual Dysfunction, Physiological Testosterone 6.0516631401
MESH:D012878 Skin Neoplasms Doxorubicin 5.4515692506
MESH:D012878 Skin Neoplasms Tetrachlorodibenzodioxin 5.4516192470
MESH:D012983 Soft Tissue Neoplasms Doxorubicin 4.4215625365 16767912 17203757
MESH:D013088 Spermatocele Ethinyl Estradiol 3.7916709447
MESH:D013274 Stomach Neoplasms arsenic trioxide 4.6317007042
MESH:D013274 Stomach Neoplasms decitabine 4.6319037991
MESH:D013274 Stomach Neoplasms Diethylnitrosamine 4.6318456281
MESH:D013274 Stomach Neoplasms Ethanol 4.6318456281
MESH:D013276 Stomach Ulcer Ethanol 3.409211565 17918041 16755016 11906479 9562338 17189318
MESH:D013375 Substance Withdrawal Syndrome Ethanol 4.129754883
MESH:D019851 Thrombophilia Ethinyl Estradiol 3.4811994571
MESH:D013927 Thrombosis Ethinyl Estradiol 3.0215669648
MESH:D013959 Thyroid Diseases Tetrachlorodibenzodioxin 3.7512697716
MESH:D013964 Thyroid Neoplasms arsenic trioxide 16.1819014326
MESH:D013964 Thyroid Neoplasms decitabine 16.1817967635
MESH:D013964 Thyroid Neoplasms Diethylnitrosamine 16.187505956
MESH:D013964 Thyroid Neoplasms Doxorubicin 16.1816010429 17909728
MESH:D016171 Torsades de Pointes arsenic trioxide 3.8115213294
MESH:D014352 Trypanosomiasis Antimony 5.7815220340
MESH:D001749 Urinary Bladder Neoplasms arsenic trioxide 8.0820435036 11780464 12845720 12973940
MESH:D001749 Urinary Bladder Neoplasms decitabine 8.0819087683 17616700
MESH:D001749 Urinary Bladder Neoplasms Doxorubicin 8.0817653716
MESH:D014581 Urticaria Acetaminophen 2.8310982225
MESH:D014594 Uterine Neoplasms Ethinyl Estradiol 3.1514692618
MESH:D014604 Uveal Neoplasms decitabine 4.7617785578
MESH:D014605 Uveitis Cyclosporine 3.831336536
MESH:D054079 Vascular Malformations Tetrachlorodibenzodioxin 4.4412125929
MESH:D014689 Venous Insufficiency coumarin 5.6312708602
MESH:D020246 Venous Thrombosis Ethinyl Estradiol 3.4015869587 14671159
MESH:D018487 Ventricular Dysfunction, Left Doxorubicin 4.0717638931 17678736 16364871 17334414
MESH:D019282 Wasting Syndrome Tetrachlorodibenzodioxin 4.1015886252
MESH:D014985 Xerophthalmia Cyclosporine 4.2917120751
No data
Pharmacogenomics Knowledge Base Top
Drug Bank Top
Drugbank ID Action Drug Name Description
DB02944 - Alpha-D-Mannose
DB03721 - O-Sialic Acid
No data
No data
No data

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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