Annotation Detail for PRPSAP2
Basic Information
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| Gene Symbol: | PRPSAP2 ( MGC117304,MGC126719,MGC126721,PAP41 ) |
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| Gene Full Name: | phosphoribosyl pyrophosphate synthetase-associated protein 2 |
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| Band: | 17p11.2 |
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| Quick Links | Entrez ID:5636; OMIM: 603762; Uniprot ID:KPRB_HUMAN; ENSEMBL ID: ENSG00000141127; HGNC ID: 9467 |
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| Relate to Another Database: |
SFARIGene;
denovo-db |
| Chemical ID |
Chemical Name |
Interaction |
Interaction Action |
Publication |
|---|
| C016403 |
2,4-dinitrotoluene |
2,4-dinitrotoluene affects the expression of PRPSAP2 mRNA | affects expression | 21346803
|
| C023514 |
2,6-dinitrotoluene |
2,6-dinitrotoluene affects the expression of PRPSAP2 mRNA | affects expression | 21346803
|
| D000082 |
Acetaminophen |
Acetaminophen affects the expression of PRPSAP2 mRNA | affects expression | 17562736
|
| D000643 |
Ammonium Chloride |
Ammonium Chloride affects the expression of PRPSAP2 mRNA | affects expression | 16483693
|
| D015032 |
Zinc |
Zinc results in increased expression of PRPSAP2 mRNA | increases expression | 17074742
|
| D019287 |
Zinc Sulfate |
Zinc Sulfate results in increased expression of PRPSAP2 mRNA | increases expression | 17074742
|
| Disease ID |
Disease Name |
Direct Evidence |
Inference Chemical Name |
Inference Score |
Publication |
|---|
| MESH:D000138 |
Acidosis |
|
Ammonium Chloride |
12.21 | 18287403 |
| MESH:D000138 |
Acidosis |
|
Zinc Sulfate |
12.21 | 7265320 |
| MESH:D000169 |
Acrodermatitis |
|
Zinc |
5.87 | 17190629 17202136 16889938 |
| MESH:D000544 |
Alzheimer Disease |
|
Zinc |
2.81 | 17119284 16580781 16325427 16410023 |
| MESH:D000755 |
Anemia, Sickle Cell |
|
Zinc |
5.28 | 16916123 |
| MESH:D000799 |
Angioedema |
|
Acetaminophen |
4.36 | 10982225 |
| MESH:D000860 |
Anoxia |
|
Zinc Sulfate |
5.48 | 7265320 |
| MESH:D001249 |
Asthma |
|
Zinc |
3.03 | 17085522 |
| MESH:D001321 |
Autistic Disorder |
|
Acetaminophen |
1.40 | 18445737 |
| MESH:D001930 |
Brain Injuries |
|
Zinc |
5.11 | 17109824 |
| MESH:D006528 |
Carcinoma, Hepatocellular |
|
2,4-dinitrotoluene |
4.73 | 16705839 |
| MESH:D006528 |
Carcinoma, Hepatocellular |
|
2,6-dinitrotoluene |
4.73 | 16705839 |
| MESH:D006528 |
Carcinoma, Hepatocellular |
|
Acetaminophen |
4.73 | 3084413 |
| MESH:D002294 |
Carcinoma, Squamous Cell |
|
Zinc |
2.97 | 16543248 |
| MESH:D002318 |
Cardiovascular Diseases |
|
Zinc |
3.87 | 16936243 |
| MESH:D002386 |
Cataract |
|
Acetaminophen |
2.75 | 10977129 |
| MESH:D002471 |
Cell Transformation, Neoplastic |
|
2,6-dinitrotoluene |
2.98 | 6135515 |
| MESH:D019465 |
Craniofacial Abnormalities |
|
Zinc |
2.44 | 19302082 |
| MESH:D003490 |
Cyanosis |
|
2,4-dinitrotoluene |
12.32 | 18551238 |
| MESH:D003490 |
Cyanosis |
|
2,6-dinitrotoluene |
12.32 | 18551238 |
| MESH:D003920 |
Diabetes Mellitus |
|
Zinc |
4.49 | 16479319 |
| MESH:D056486 |
Drug-Induced Liver Injury |
|
2,4-dinitrotoluene |
6.62 | 18551238 21346803 |
| MESH:D056486 |
Drug-Induced Liver Injury |
|
2,6-dinitrotoluene |
6.62 | 21346803 18551238 |
| MESH:D056486 |
Drug-Induced Liver Injury |
|
Acetaminophen |
6.62 | 16485898 11529661 10774834 12705907 17562736 17906064 16177239 12153990 19420014 12958197 14550746 14725611 16227642 12540782 19164858 16781746 12392966 10663392 16393943 10915739 11739529 17522070 15619225 11287661 18713872 11421492 19370779 19416960 14986274 11461765 19085960 18071297 16109766 15968718 19923254 19739265 12594235 2444490 11834606 16081117 11743745 |
| MESH:D056487 |
Drug-Induced Liver Injury, Chronic |
|
Acetaminophen |
4.62 | 19426721 |
| MESH:D004938 |
Esophageal Neoplasms |
|
Zinc |
2.92 | 16543248 |
| MESH:D005756 |
Gastritis |
|
Acetaminophen |
12.97 | 16983495 |
| MESH:D005756 |
Gastritis |
|
Zinc |
12.97 | 17241300 |
| MESH:D006130 |
Growth Disorders |
|
Zinc |
4.15 | 17217573 |
| MESH:D006333 |
Heart Failure |
|
Zinc |
3.78 | 17162251 |
| MESH:D006335 |
Heart Injuries |
|
Zinc |
6.29 | 17074742 |
| MESH:D016481 |
Helicobacter Infections |
|
Zinc |
4.88 | 17241300 |
| MESH:D006527 |
Hepatolenticular Degeneration |
|
Zinc |
12.75 | 17276780 |
| MESH:D006527 |
Hepatolenticular Degeneration |
|
Zinc Sulfate |
12.75 | 17063115 |
| MESH:D006930 |
Hyperalgesia |
|
Acetaminophen |
2.95 | 16870215 |
| MESH:D007022 |
Hypotension |
|
Zinc Sulfate |
4.82 | 7265320 |
| MESH:D007511 |
Ischemia |
|
Zinc |
5.05 | 16584753 |
| MESH:D007674 |
Kidney Diseases |
|
Acetaminophen |
6.70 | 12587719 15629191 |
| MESH:D007674 |
Kidney Diseases |
|
Zinc |
6.70 | 16960431 |
| MESH:D007676 |
Kidney Failure, Chronic |
|
Zinc |
4.75 | 16518626 |
| MESH:D007680 |
Kidney Neoplasms |
|
2,4-dinitrotoluene |
8.27 | 16705839 |
| MESH:D007680 |
Kidney Neoplasms |
|
2,6-dinitrotoluene |
8.27 | 16705839 |
| MESH:D016773 |
Leishmaniasis, Cutaneous |
|
Zinc Sulfate |
4.53 | 15237267 |
| MESH:D008107 |
Liver Diseases |
|
Acetaminophen |
1.69 | 19014921 11587558 19460945 12587719 19784758 16611625 16610002 12969438 |
| MESH:D017114 |
Liver Failure, Acute |
|
Acetaminophen |
3.54 | 16871587 17185352 |
| MESH:D008113 |
Liver Neoplasms |
|
2,6-dinitrotoluene |
2.24 | 7678174 |
| MESH:D008114 |
Liver Neoplasms, Experimental |
|
2,6-dinitrotoluene |
2.72 | 2876784 2876786 6135515 |
| MESH:D008325 |
Mammary Neoplasms, Experimental |
|
Zinc |
3.48 | 12773700 |
| MESH:D008546 |
Melanoma, Experimental |
|
Acetaminophen |
3.98 | 19513568 |
| MESH:D009336 |
Necrosis |
|
2,4-dinitrotoluene |
11.94 | 18551238 |
| MESH:D009336 |
Necrosis |
|
2,6-dinitrotoluene |
11.94 | 18551238 7678174 |
| MESH:D019636 |
Neurodegenerative Diseases |
|
Acetaminophen |
3.14 | 18514411 |
| MESH:D009784 |
Occupational Diseases |
|
2,4-dinitrotoluene |
9.92 | 16049721 12819281 |
| MESH:D009784 |
Occupational Diseases |
|
2,6-dinitrotoluene |
9.92 | 16049721 |
| MESH:D010146 |
Pain |
|
Acetaminophen |
2.65 | 16870215 |
| MESH:D011225 |
Pre-Eclampsia |
|
Zinc |
4.42 | 17114810 |
| MESH:D011471 |
Prostatic Neoplasms |
|
Zinc |
3.77 | 16700911 16517595 16606632 12429649 |
| MESH:D012162 |
Retinal Degeneration |
|
Zinc |
4.36 | 16584753 |
| MESH:D012640 |
Seizures |
|
2,4-dinitrotoluene |
6.56 | 18551238 |
| MESH:D012640 |
Seizures |
|
2,6-dinitrotoluene |
6.56 | 18551238 |
| MESH:D014062 |
Tongue Neoplasms |
|
Zinc |
4.70 | 16543248 |
| MESH:D001749 |
Urinary Bladder Neoplasms |
|
2,4-dinitrotoluene |
5.36 | 16049721 |
| MESH:D001749 |
Urinary Bladder Neoplasms |
|
2,6-dinitrotoluene |
5.36 | 16049721 |
| MESH:D014571 |
Urologic Neoplasms |
|
2,4-dinitrotoluene |
13.58 | 10091137 |
| MESH:D014571 |
Urologic Neoplasms |
|
2,6-dinitrotoluene |
13.58 | 10091137 |
| MESH:D014581 |
Urticaria |
|
Acetaminophen |
3.33 | 10982225 |
Related Pathway Information