AutismKB 2.0

Annotation Detail for RELN


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Basic Information Top
Gene Symbol:RELN ( PRO1598,RL )
Gene Full Name: reelin
Band: 7q22.1
Quick LinksEntrez ID:5649; OMIM: 600514; Uniprot ID:RELN_HUMAN; ENSEMBL ID: ENSG00000189056; HGNC ID: 9957
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
No data
Pathway IDPathway Name
hsa04512ECM-receptor interaction
hsa04510Focal adhesion
No data
Pathway IDPathway Name
200114Lissencephaly gene (LIS1) in neuronal migration and development
200051Reelin signaling pathway
No data
No data
Related Diseases/Disorders Top
No data
No data
Desease Name
multiple sclerosis (age of onset)
CHEMDEPENDENCY
PSYCH
Otosclerosis
IMMUNE
smoking cessation
schizophrenia
Autism
Desease Name
Alzheimer's disease
Schizophrenia
Otosclerosis
Multiple sclerosis (age of onset)
Desease Name
Lissencephaly syndrome, Norman-Roberts type
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
D000082 Acetaminophen Acetaminophen affects the expression of RELN mRNAaffects expression 17562736
D019342 Acetic Acid Acetic Acid results in increased expression of RELN mRNAincreases expression 17065238
D000643 Ammonium Chloride Ammonium Chloride affects the expression of RELN mRNAaffects expression 16483693
D001564 Benzo(a)pyrene Benzo(a)pyrene results in decreased expression of RELN mRNAdecreases expression 20106945
D002251 Carbon Tetrachloride Carbon Tetrachloride affects the expression of RELN mRNAaffects expression 17484886
D003024 Clozapine Clozapine results in decreased expression of RELN mRNAdecreases expression 17266109
D003024 Clozapine Clozapine results in decreased methylation of RELN promoterdecreases methylation 18757738
D003024 Clozapine Valproic Acid promotes the reaction [Clozapine results in decreased methylation of RELN promoter]decreases methylation|increases reaction 18757738
D003024 Clozapine Clozapine results in decreased expression of RELN proteindecreases expression 19359144
D004041 Dietary Fats Dietary Fats results in increased expression of RELN mRNAincreases expression 18042831
D004054 Diethylstilbestrol Diethylstilbestrol results in increased expression of RELN mRNAincreases expression 19371625
D004128 Dimethylnitrosamine Dimethylnitrosamine results in decreased expression of RELN mRNAdecreases expression 17547211
D004121 Dimethyl Sulfoxide Dimethyl Sulfoxide results in increased expression of RELN mRNAincreases expression 17065238
D004317 Doxorubicin Doxorubicin inhibits the reaction [DNMT1 binds to RELN promoter]affects binding|decreases reaction 17065238
D004317 Doxorubicin [Doxorubicin inhibits the reaction [DNMT1 binds to RELN promoter]] which results in increased expression of RELN mRNAaffects binding|decreases reaction|increases expression 17065238
D004317 Doxorubicin Doxorubicin results in increased expression of RELN mRNAincreases expression 17065238
D004997 Ethinyl Estradiol Ethinyl Estradiol results in increased expression of RELN mRNAincreases expression 17942748
D004997 Ethinyl Estradiol [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of RELN mRNAaffects cotreatment|increases expression 17942748
D005038 Ethylnitrosourea Ethylnitrosourea results in increased mutagenesis of RELN geneincreases mutagenesis 16495775
D005473 Fluoxetine Fluoxetine results in increased expression of RELN mRNAincreases expression 19359144
D006220 Haloperidol Haloperidol results in decreased expression of RELN mRNAdecreases expression 19359144
D006220 Haloperidol Haloperidol results in decreased expression of RELN proteindecreases expression 19359144
D008094 Lithium Lithium results in decreased expression of RELN mRNAdecreases expression 19359144
D008094 Lithium Lithium results in decreased expression of RELN proteindecreases expression 19359144
D008628 Mercury Mercury results in decreased expression of RELN mRNAdecreases expression 17547211
D008715 Methionine Methionine results in decreased expression of RELN mRNAdecreases expression 15737665
15671176
D008715 Methionine Methionine results in increased methylation of RELN promoterincreases methylation 15737665
15671176
D008715 Methionine Valproic Acid inhibits the reaction [Methionine results in increased methylation of RELN promoter]decreases reaction|increases methylation 15737665
D008769 Methylnitronitrosoguanidine Methylnitronitrosoguanidine results in increased expression of RELN mRNAincreases expression 15120970
D009151 Mustard Gas Mustard Gas results in decreased expression of RELN mRNAdecreases expression 15674843
C076029 olanzapine olanzapine results in increased expression of RELN mRNAincreases expression 19359144
C076029 olanzapine olanzapine results in increased expression of RELN proteinincreases expression 19359144
C009618 O,O-diethyl O-3,5,6-trichloro-2-pyridyl phosphate RELN gene affects the susceptibility to O,O-diethyl O-3,5,6-trichloro-2-pyridyl phosphateaffects response to substance 16783542
C041786 palm oil palm oil results in increased expression of RELN mRNAincreases expression 18042831
D010622 Phencyclidine Phencyclidine results in decreased expression of RELN mRNAdecreases expression 17266109
D010634 Phenobarbital NR1I3 protein affects the reaction [Phenobarbital results in decreased expression of RELN mRNA]affects reaction|decreases expression 19482888
D010634 Phenobarbital Phenobarbital results in decreased expression of RELN mRNAdecreases expression 19482888
C006253 pirinixic acid [pirinixic acid binds to and results in increased activity of PPARA protein] which results in decreased expression of RELN mRNAaffects binding|decreases expression|increases activity 19710929
C059514 resveratrol resveratrol results in increased expression of RELN mRNAincreases expression 19371625
D013469 Sulpiride Sulpiride results in decreased methylation of RELN promoterdecreases methylation 18757738
19110320
D013469 Sulpiride Valproic Acid promotes the reaction [Sulpiride results in decreased methylation of RELN promoter]decreases methylation|increases reaction 18757738
19110320
D013749 Tetrachlorodibenzodioxin [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of RELN mRNAaffects cotreatment|increases expression 17942748
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in increased expression of RELN mRNAincreases expression 15328365
D014303 Trinitrotoluene Trinitrotoluene affects the expression of RELN mRNAaffects expression 21346803
D014635 Valproic Acid Valproic Acid inhibits the reaction [Methionine results in increased methylation of RELN promoter]decreases reaction|increases methylation 15737665
D014635 Valproic Acid Valproic Acid promotes the reaction [Clozapine results in decreased methylation of RELN promoter]decreases methylation|increases reaction 18757738
D014635 Valproic Acid Valproic Acid promotes the reaction [Sulpiride results in decreased methylation of RELN promoter]decreases methylation|increases reaction 18757738
19110320
C025643 vinclozolin vinclozolin affects the expression of RELN mRNAaffects expression 19015723
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000014 Abnormalities, Drug-Induced Phenobarbital 17.806195326
MESH:D000014 Abnormalities, Drug-Induced Tetrachlorodibenzodioxin 17.8015322242 11752688 14514962
MESH:D000014 Abnormalities, Drug-Induced Trinitrotoluene 17.807525203
MESH:D000014 Abnormalities, Drug-Induced Valproic Acid 17.808875741
MESH:D000015 Abnormalities, Multiple Valproic Acid 3.6519490988
MESH:D000138 Acidosis Ammonium Chloride 3.2518287403
MESH:D000152 Acne Vulgaris Ethinyl Estradiol 3.6317505938
MESH:D058186 Acute Kidney Injury resveratrol 3.5816538975
MESH:D055371 Acute Lung Injury pirinixic acid 2.8318653653
MESH:D000230 Adenocarcinoma Benzo(a)pyrene 9.5020127859 20464547
MESH:D000230 Adenocarcinoma Dimethylnitrosamine 9.5016033868
MESH:D000230 Adenocarcinoma Doxorubicin 9.5017418594
MESH:D000230 Adenocarcinoma Ethinyl Estradiol 9.5014692618
MESH:D000236 Adenoma Benzo(a)pyrene 14.576695378
MESH:D000236 Adenoma Dimethylnitrosamine 14.5719555203
MESH:D000236 Adenoma Ethylnitrosourea 14.576695378
MESH:D000236 Adenoma resveratrol 14.5715688382
MESH:D018248 Adenoma, Liver Cell Phenobarbital 15.4817620307
MESH:D018248 Adenoma, Liver Cell pirinixic acid 15.4816434500
MESH:D018248 Adenoma, Liver Cell Tetrachlorodibenzodioxin 15.4816835633
MESH:D000380 Agranulocytosis Clozapine 4.7512649775 14617031 16160616
MESH:D000419 Albuminuria Doxorubicin 4.2521441931
MESH:D000544 Alzheimer Disease Lithium 4.5019621015
MESH:D000544 Alzheimer Disease resveratrol 4.5016183991 16162502
MESH:D000550 Amblyopia Valproic Acid 4.9217688650
MESH:D000686 Amyloidosis Diethylstilbestrol 4.1815469931
MESH:D000740 Anemia Tetrachlorodibenzodioxin 2.6811748828
MESH:D000799 Angioedema Acetaminophen 3.5310982225
MESH:D001008 Anxiety Disorders Fluoxetine 13.5718083778
MESH:D001008 Anxiety Disorders Valproic Acid 13.5717497229
MESH:D001008 Anxiety Disorders vinclozolin 13.5719015723
MESH:D017544 Aortic Aneurysm, Abdominal Benzo(a)pyrene 3.7719183758
MESH:D001161 Arteriosclerosis Dietary Fats 8.9015238619
MESH:D001161 Arteriosclerosis Ethinyl Estradiol 8.9011256880
MESH:D001169 Arthritis, Experimental Ethinyl Estradiol 6.7215885639
MESH:D001169 Arthritis, Experimental resveratrol 6.7217115116
MESH:D001249 Asthma Mustard Gas 2.6210378619
MESH:D050197 Atherosclerosis resveratrol 3.0916873680 17967414
MESH:D001321 Autistic Disorder marker/mechanism 11814262 11317216 20442744
MESH:D001321 Autistic Disorder Acetaminophen 5.6418445737
MESH:D001321 Autistic Disorder Fluoxetine 5.6419232924 18775368
MESH:D001321 Autistic Disorder Haloperidol 5.6418080171 19368416
MESH:D001321 Autistic Disorder Mercury 5.6417497416
MESH:D001321 Autistic Disorder Methionine 5.6419056591 16917939 19267885
MESH:D001321 Autistic Disorder olanzapine 5.6417069543 18685284
MESH:D001321 Autistic Disorder Valproic Acid 5.6418396377 17507914 16609825 17688650 18775368 20603192 18940202 18316065 15238991 17157402 18985861 18558336 18177632 19460635 19232924
MESH:D001327 Autoimmune Diseases Mercury 4.5716634805
MESH:D001714 Bipolar Disorder marker/mechanism 11126396 14708030
MESH:D001714 Bipolar Disorder Lithium 7.0920338123 17594078 20046352 19153942
MESH:D001714 Bipolar Disorder Valproic Acid 7.0917594078 20046352
MESH:D001768 Blister Mustard Gas 4.8519167455
MESH:D001778 Blood Coagulation Disorders pirinixic acid 7.8519483382
MESH:D001778 Blood Coagulation Disorders Tetrachlorodibenzodioxin 7.8512125929
MESH:D001836 Body Weight Changes Tetrachlorodibenzodioxin 3.4715340226
MESH:D001848 Bone Diseases, Developmental Tetrachlorodibenzodioxin 7.3615746008
MESH:D001848 Bone Diseases, Developmental Valproic Acid 7.368888407
MESH:D019046 Bone Marrow Neoplasms Doxorubicin 4.3814601052
MESH:D001927 Brain Diseases Ethylnitrosourea 4.6114991843
MESH:D002545 Brain Ischemia resveratrol 3.9717600658
MESH:D001932 Brain Neoplasms Doxorubicin 8.2017150277
MESH:D001932 Brain Neoplasms Ethylnitrosourea 8.2016651633 15144691 16436596 18412241 16357521
MESH:D001943 Breast Neoplasms Benzo(a)pyrene 2.8020146248 17474063
MESH:D001943 Breast Neoplasms Dietary Fats 2.8020435547
MESH:D001943 Breast Neoplasms Diethylstilbestrol 2.8017129689 15324884
MESH:D001943 Breast Neoplasms Doxorubicin 2.8016096432 18695136 19526202 15994142 15136595 16595493 16115903 17426702 17983394 15634643 18628466 15692762 11325840 15567936 17369602 16322301 16935488 15939500 18234424 16826403 18382427 16264153 15993339 15668708
MESH:D001943 Breast Neoplasms resveratrol 2.8017651959 17534123 16393696
MESH:D001943 Breast Neoplasms Tetrachlorodibenzodioxin 2.8020435547
MESH:D001989 Bronchiolitis Obliterans Mustard Gas 4.8515286001
MESH:D029481 Bronchitis, Chronic Mustard Gas 4.6617687719 10378619
MESH:D002252 Carbon Tetrachloride Poisoning Carbon Tetrachloride 3.4816097048 16227642 16011737 18705752 16124888 15721981 10355542 15673190 3786805 16050911 16192424 15700767
MESH:D002276 Carcinoid Tumor Doxorubicin 4.4916051944
MESH:D002277 Carcinoma Dimethylnitrosamine 7.5519555203
MESH:D002277 Carcinoma Tetrachlorodibenzodioxin 7.5516835633
MESH:D006528 Carcinoma, Hepatocellular Acetaminophen 10.673084413
MESH:D006528 Carcinoma, Hepatocellular Carbon Tetrachloride 10.6718788625
MESH:D006528 Carcinoma, Hepatocellular Diethylstilbestrol 10.6716924424 15948411
MESH:D006528 Carcinoma, Hepatocellular Doxorubicin 10.6716234567 17876044 16023760 18059187
MESH:D006528 Carcinoma, Hepatocellular Phenobarbital 10.6720935162 17173139 1701930 20007298 6705139
MESH:D006528 Carcinoma, Hepatocellular resveratrol 10.6719321006 16227395
MESH:D018827 Carcinoma, Lewis Lung resveratrol 4.2816675471
MESH:D002292 Carcinoma, Renal Cell Doxorubicin 3.011485588 16201981
MESH:D002294 Carcinoma, Squamous Cell Benzo(a)pyrene 10.0520419170
MESH:D002294 Carcinoma, Squamous Cell Dimethylnitrosamine 10.0516033868
MESH:D002294 Carcinoma, Squamous Cell Doxorubicin 10.056189445
MESH:D002294 Carcinoma, Squamous Cell resveratrol 10.0516227395
MESH:D006332 Cardiomegaly Tetrachlorodibenzodioxin 2.2018670907 18850075 16120746
MESH:D009202 Cardiomyopathies Doxorubicin 3.3316612575 17131338 16731534 16651473 15811867 16455267 17928571 15505089 15792986 16109756 16269455 16364871 17382496 17308081 16278810 18627295 16952015 15476868 17924179 17329180 17974986 17519947 17351982 17007740 16242529
MESH:D002311 Cardiomyopathy, Dilated Doxorubicin 5.8117334414 16243910
MESH:D002311 Cardiomyopathy, Dilated Mercury 5.8110334427
MESH:D002318 Cardiovascular Diseases resveratrol 3.2615458977
MESH:D002375 Catalepsy Haloperidol 4.6015215559 1977408
MESH:D002386 Cataract Acetaminophen 6.9010977129
MESH:D002386 Cataract Trinitrotoluene 6.9015817613 14694615
MESH:D002389 Catatonia olanzapine 5.9318071103 16772815
MESH:D002471 Cell Transformation, Neoplastic Ethylnitrosourea 6.7616003739
MESH:D002471 Cell Transformation, Neoplastic Methylnitronitrosoguanidine 6.762727394
MESH:D002493 Central Nervous System Diseases Phenobarbital 3.954080065
MESH:D016543 Central Nervous System Neoplasms Ethylnitrosourea 5.6717160924
MESH:D002659 Child Development Disorders, Pervasive Methionine 6.1119267885
MESH:D002659 Child Development Disorders, Pervasive Valproic Acid 6.1120734317
MESH:D018281 Cholangiocarcinoma Tetrachlorodibenzodioxin 2.9016835633
MESH:D002779 Cholestasis Ethinyl Estradiol 6.9911677210 17681005 16105132 16919318 15861022 17333356 17110522
MESH:D002779 Cholestasis pirinixic acid 6.9919176532
MESH:D002972 Cleft Palate Tetrachlorodibenzodioxin 1.9716354765 15340226 8697196 12621046 15668235
MESH:D003072 Cognition Disorders Clozapine 4.6617123785
MESH:D003092 Colitis resveratrol 3.8316474422
MESH:D003110 Colonic Neoplasms resveratrol 2.4116338953
MESH:D015179 Colorectal Neoplasms Doxorubicin 2.6518259882 18802399
MESH:D015179 Colorectal Neoplasms resveratrol 2.6516550006
MESH:D000013 Congenital Abnormalities Tetrachlorodibenzodioxin 8.4114669216 17141729
MESH:D000013 Congenital Abnormalities Trinitrotoluene 8.4115095906
MESH:D003327 Coronary Disease resveratrol 3.5516507316
MESH:D019465 Craniofacial Abnormalities Tetrachlorodibenzodioxin 2.3710048152 15322242 20055451
MESH:D019465 Craniofacial Abnormalities Valproic Acid 2.378888407 16575769 17688650
MESH:D003456 Cryptorchidism Diethylstilbestrol 10.3912952375 16002989
MESH:D003456 Cryptorchidism vinclozolin 10.3914966744
MESH:D003490 Cyanosis Trinitrotoluene 4.6218551238
MESH:D007644 Darier Disease Lithium 5.6020338123
MESH:D016757 Death, Sudden, Cardiac Haloperidol 4.5620210726
MESH:D003704 Dementia Haloperidol 4.3011575062
MESH:D003866 Depressive Disorder marker/mechanism 14708030
MESH:D003866 Depressive Disorder Fluoxetine 4.3815014590
MESH:D003865 Depressive Disorder, Major marker/mechanism 11126396
MESH:D017449 Dermatitis, Allergic Contact Mercury 3.5116823706
MESH:D003876 Dermatitis, Atopic pirinixic acid 2.2818249437
MESH:D002658 Developmental Disabilities olanzapine 4.4817069543
MESH:D018500 Diabetes Insipidus, Nephrogenic Lithium 5.4419244398
MESH:D003921 Diabetes Mellitus, Experimental resveratrol 3.5216873680
MESH:D003924 Diabetes Mellitus, Type 2 Clozapine 4.2316402076
MESH:D003924 Diabetes Mellitus, Type 2 Tetrachlorodibenzodioxin 4.2317107852
MESH:D003928 Diabetic Nephropathies resveratrol 3.7016286809
MESH:D006970 Disorders of Excessive Somnolence Clozapine 5.2415331141
MESH:D056486 Drug-Induced Liver Injury Acetaminophen 17.1614550746 16081117 2444490 17522070 19420014 11421492 10663392 16393943 15619225 12705907 19923254 19416960 14725611 11834606 12540782 16227642 12153990 18071297 16781746 11461765 18713872 19370779 11529661 10915739 11743745 19085960 19739265 15968718 11739529 14986274 19164858 17906064 16177239 12392966 16485898 12958197 11287661 16109766 17562736 10774834 12594235
MESH:D056486 Drug-Induced Liver Injury Carbon Tetrachloride 17.1615968718 16227642 19336974 7440962 6884620 10915739 15998439 21278145 10092053 2869522 3786805 16177239 7179309 19085960 11566570 4309450 6623471 3732212 15027814 7120509 9327722 17522070
MESH:D056486 Drug-Induced Liver Injury Dimethylnitrosamine 17.168172417
MESH:D056486 Drug-Induced Liver Injury Doxorubicin 17.1617416283
MESH:D056486 Drug-Induced Liver Injury Tetrachlorodibenzodioxin 17.1620420201
MESH:D056486 Drug-Induced Liver Injury Trinitrotoluene 17.1618551238 21346803
MESH:D056486 Drug-Induced Liver Injury Valproic Acid 17.1619641884 1733752
MESH:D056487 Drug-Induced Liver Injury, Chronic Acetaminophen 3.7819426721
MESH:D004362 Drug Toxicity Doxorubicin 7.3518602426
MESH:D004362 Drug Toxicity Tetrachlorodibenzodioxin 7.3511462148
MESH:D050171 Dyslipidemias Clozapine 8.1316402076
MESH:D050171 Dyslipidemias Dietary Fats 8.1318367378
MESH:D004421 Dystonia Phenobarbital 9.481851702
MESH:D004421 Dystonia Valproic Acid 9.481851702
MESH:D004476 Ectodermal Dysplasia Ethylnitrosourea 5.6718357618
MESH:D004487 Edema Fluoxetine 18.7412798668
MESH:D004487 Edema Mustard Gas 18.749260866 11428631 11428647 11402378
MESH:D004487 Edema pirinixic acid 18.7412083418
MESH:D004487 Edema resveratrol 18.748985016
MESH:D004487 Edema Tetrachlorodibenzodioxin 18.7411000095 12711302
MESH:D004489 Edema, Cardiac Tetrachlorodibenzodioxin 3.5916714409 18230668 15322242
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Ethinyl Estradiol 8.1412538720
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental resveratrol 8.1417872969
MESH:D018159 Endolymphatic Hydrops Dimethyl Sulfoxide 6.2420641076
MESH:D004714 Endometrial Hyperplasia Diethylstilbestrol 4.3816402032
MESH:D016889 Endometrial Neoplasms Diethylstilbestrol 7.0515700306 16804899
MESH:D016889 Endometrial Neoplasms Doxorubicin 7.0517359293
MESH:D004715 Endometriosis Tetrachlorodibenzodioxin 2.7610568697 9294722
MESH:D004719 Endomyocardial Fibrosis Doxorubicin 4.8418037988
MESH:D020345 Enterocolitis, Necrotizing resveratrol 4.5417923197
MESH:D004831 Epilepsies, Myoclonic Phenobarbital 9.783659116
MESH:D004831 Epilepsies, Myoclonic Valproic Acid 9.7817275665 3659116
MESH:D004828 Epilepsies, Partial Phenobarbital 8.923922381 11558140
MESH:D004828 Epilepsies, Partial Valproic Acid 8.923922381 16628512
MESH:D004827 Epilepsy Phenobarbital 6.1320417680
MESH:D004827 Epilepsy Valproic Acid 6.1318234410 20417680
MESH:D004832 Epilepsy, Absence Phenobarbital 8.006401628
MESH:D004832 Epilepsy, Absence Valproic Acid 8.006254150 7562514 6426943
MESH:D017029 Epilepsy, Complex Partial Phenobarbital 10.297750514
MESH:D017029 Epilepsy, Complex Partial Valproic Acid 10.297750514
MESH:D004830 Epilepsy, Tonic-Clonic Phenobarbital 9.443659116
MESH:D004830 Epilepsy, Tonic-Clonic Valproic Acid 9.443659116
MESH:D004890 Erythema Mustard Gas 4.859357497
MESH:D004938 Esophageal Neoplasms Benzo(a)pyrene 4.3716530937
MESH:D004938 Esophageal Neoplasms Dimethylnitrosamine 4.3717016578
MESH:D005124 Eye Abnormalities Tetrachlorodibenzodioxin 2.7811564622
MESH:D005234 Fatty Liver Carbon Tetrachloride 21.7061145 12631006 15959796 12795759 19224547 16045604 17595544 16239168
MESH:D005234 Fatty Liver Dietary Fats 21.7019551842 18296743 19004024 17967931
MESH:D005234 Fatty Liver Ethinyl Estradiol 21.7015345470
MESH:D005234 Fatty Liver pirinixic acid 21.7019236843 20131406
MESH:D005234 Fatty Liver Valproic Acid 21.7019224547 14986274
MESH:D052776 Female Urogenital Diseases Diethylstilbestrol 3.4715751030 16513791 16002989 16534752 16611131
MESH:D005313 Fetal Death Tetrachlorodibenzodioxin 3.1511858732
MESH:D005315 Fetal Diseases Valproic Acid 4.5716575769
MESH:D005317 Fetal Growth Retardation Valproic Acid 3.8418558336 8888407
MESH:D018222 Fibromatosis, Aggressive Doxorubicin 4.2819069698
MESH:D005355 Fibrosis Carbon Tetrachloride 13.0018705752
MESH:D005355 Fibrosis Dietary Fats 13.0018296743
MESH:D005355 Fibrosis Tetrachlorodibenzodioxin 13.0020067830
MESH:D005756 Gastritis Acetaminophen 3.3616983495
MESH:D030342 Genetic Diseases, Inborn vinclozolin 4.6216973722
MESH:D005832 Genital Diseases, Male vinclozolin 4.9816417039
MESH:D005833 Genital Neoplasms, Female Diethylstilbestrol 4.6416452187
MESH:D005909 Glioblastoma Doxorubicin 6.8817150277
MESH:D005909 Glioblastoma Ethylnitrosourea 6.8816436596
MESH:D005910 Glioma Ethylnitrosourea 3.3718412241 16651633 16357521
MESH:D006058 Gonadal Disorders Tetrachlorodibenzodioxin 4.2810696789
MESH:D006258 Head and Neck Neoplasms Doxorubicin 3.3215692506
MESH:D034381 Hearing Loss Dimethyl Sulfoxide 4.9120641076
MESH:D006330 Heart Defects, Congenital Benzo(a)pyrene 10.3120471113
MESH:D006330 Heart Defects, Congenital Lithium 10.3119638421
MESH:D006330 Heart Defects, Congenital Tetrachlorodibenzodioxin 10.3111294989 10048152
MESH:D006331 Heart Diseases Doxorubicin 3.2718674790 12587719 16330681 16144979 17875725 16244371 18006777 14766674 16707910 17888722 16879835 16244372 16495754
MESH:D006333 Heart Failure Doxorubicin 6.4117481944
MESH:D006333 Heart Failure pirinixic acid 6.4120558911
MESH:D006394 Hemangiosarcoma Doxorubicin 3.6315692506
MESH:D006470 Hemorrhage Tetrachlorodibenzodioxin 3.0611000095
MESH:D006505 Hepatitis Carbon Tetrachloride 3.3019110552 19900420
MESH:D006529 Hepatomegaly Phenobarbital 18.2016109766
MESH:D006529 Hepatomegaly pirinixic acid 18.2019176532 18467677 19772884 16221962
MESH:D006529 Hepatomegaly Tetrachlorodibenzodioxin 18.2015340226 12621046 16120746
MESH:D006529 Hepatomegaly Trinitrotoluene 18.2015817613
MESH:D006561 Herpes Simplex resveratrol 3.8716876885
MESH:D006689 Hodgkin Disease Doxorubicin 3.1615147373 18501091 17606976
MESH:D019584 Hot Flashes Fluoxetine 5.0014716179
MESH:D006849 Hydrocephalus Valproic Acid 4.5617688650
MESH:D006869 Hydronephrosis Tetrachlorodibenzodioxin 3.7316354765 8697196 18606429 16959395 15340226
MESH:D006930 Hyperalgesia Acetaminophen 2.4616870215
MESH:D006932 Hyperbilirubinemia Carbon Tetrachloride 4.2216899240
MESH:D006937 Hypercholesterolemia Dietary Fats 8.2921332399
MESH:D006937 Hypercholesterolemia resveratrol 8.2917188708
MESH:D006943 Hyperglycemia pirinixic acid 2.9220558911
MESH:D006948 Hyperkinesis Clozapine 4.6016046005
MESH:D006949 Hyperlipidemias Dietary Fats 8.3421332399
MESH:D006949 Hyperlipidemias resveratrol 8.3416873680
MESH:D006963 Hyperphagia olanzapine 5.9217933447
MESH:D006965 Hyperplasia Diethylstilbestrol 4.1312960047 14722030
MESH:D006973 Hypertension Tetrachlorodibenzodioxin 1.7918670907 18850075
MESH:D006975 Hypertension, Portal Carbon Tetrachloride 3.7815338365
MESH:D017379 Hypertrophy, Left Ventricular resveratrol 4.0317488730
MESH:D007021 Hypospadias Diethylstilbestrol 10.2316002989
MESH:D007021 Hypospadias Ethinyl Estradiol 10.2316945680 16569931
MESH:D020244 Infarction, Middle Cerebral Artery resveratrol 4.3417600658
MESH:D007246 Infertility Diethylstilbestrol 4.0615036965
MESH:D007247 Infertility, Female Ethinyl Estradiol 3.1812013081
MESH:D007248 Infertility, Male Ethinyl Estradiol 10.1017937319
MESH:D007248 Infertility, Male Trinitrotoluene 10.1012150543
MESH:D007248 Infertility, Male vinclozolin 10.1016467254
MESH:D007249 Inflammation Dietary Fats 14.1520412841
MESH:D007249 Inflammation Fluoxetine 14.1512798668
MESH:D007249 Inflammation Mustard Gas 14.1511428647 9260866 16001271 9357497 11402378 8975870 11428631 17524151 11428620
MESH:D007249 Inflammation resveratrol 14.1516366677
MESH:D007249 Inflammation Tetrachlorodibenzodioxin 14.1512878042 12200463
MESH:D007251 Influenza, Human resveratrol 4.2316624496
MESH:D007333 Insulin Resistance Dietary Fats 6.5711836018 18457598
MESH:D007333 Insulin Resistance pirinixic acid 6.5716306350
MESH:D007569 Jaw Abnormalities Tetrachlorodibenzodioxin 3.0616580747
MESH:D007674 Kidney Diseases Acetaminophen 9.1615629191 12587719
MESH:D007674 Kidney Diseases Doxorubicin 9.1615699352 16775033 15369732
MESH:D007674 Kidney Diseases Mercury 9.1617934191
MESH:D007676 Kidney Failure, Chronic Doxorubicin 3.8816707910
MESH:D007680 Kidney Neoplasms Diethylstilbestrol 7.0716762066 15003126 14681315
MESH:D007680 Kidney Neoplasms Ethylnitrosourea 7.0717379185
MESH:D007859 Learning Disorders Diethylstilbestrol 3.7617184923
MESH:D004915 Leukemia, Erythroblastic, Acute Doxorubicin 4.8416085563
MESH:D015470 Leukemia, Myeloid, Acute Valproic Acid 2.1016294345 17596541
MESH:D015473 Leukemia, Promyelocytic, Acute resveratrol 3.3816087638
MESH:D007984 Leydig Cell Tumor vinclozolin 4.4216417039
MESH:D008064 Lipidoses Clozapine 7.9017567588
MESH:D008064 Lipidoses Fluoxetine 7.9017567588 15342952
MESH:D054082 Lissencephaly marker/mechanism
MESH:D008103 Liver Cirrhosis Carbon Tetrachloride 10.0316239168 11408273 17334410 16943688 17174718 17157831 16221502 21278145 11903743
MESH:D008103 Liver Cirrhosis Dietary Fats 10.0318296743
MESH:D008103 Liver Cirrhosis Phenobarbital 10.0321047994
MESH:D008106 Liver Cirrhosis, Experimental Carbon Tetrachloride 10.2716136751 12667390 15818738 18263696 12632514 16116963 17714472 12586293 17708605 16011737 18412020 17869086 12649538 17976157 12898905 12445418 15931870 12445421 15338365 18339082 15730626 17640975 13678700 15893842 18277467 12741479 15673190 15925388 16638106 15876570 18376398 18166357 17557913 18705752 17631135 18395095 12632512 12609069 18210741 18420326 17761835 17823541 17922224 11481614 16248980 16027843 18418968 18006644 12546737 12389079 18472094 17944888 17766677 15370692 14748882 18429990 18187930 10355542 12958196 18156304 18395914 14512876 18251166 14724832 17805973 17698563 16192424 17721639 14716833 18279442 15996030 12666154 18472332 18054572 18205269 20821823 15123356 15052691 16015684 14620537 18317297 17481882 14716496 15650968 17565644 15959796 17900296 15362042 18481824 15057751 16097048 17525996 16033810
MESH:D008106 Liver Cirrhosis, Experimental Dimethylnitrosamine 10.2715733078 15723089 15369754 15161499 17036385 17724770 15339415 17203207 18364076 18637143 15099470 18629640 17348192 18210741 15366600 14659978 17465448 14643895 15864749 16570917 17432682 15591649 17201889 18239293 15081153 16169303 15492853 16603200 17719030 15138612 16627068 18567088 12918455 17196135 18095165 15744066 15763062 15793283 16270385 12925901 15067225 16544323 15383259 17534399 16042886 15577212 18237412 15571005 18371158 15298665 14709902 15798949 15086199 17198567 14726149 17881167 17666798 17640959 15842777 16009107 15942678 15504291 14568256 15479170 18672772
MESH:D008106 Liver Cirrhosis, Experimental Dimethyl Sulfoxide 10.2711682029
MESH:D008106 Liver Cirrhosis, Experimental Doxorubicin 10.2716439617 16595196
MESH:D008106 Liver Cirrhosis, Experimental Methionine 10.2715158331
MESH:D008106 Liver Cirrhosis, Experimental pirinixic acid 10.2715474484
MESH:D008106 Liver Cirrhosis, Experimental Tetrachlorodibenzodioxin 10.2712878042
MESH:D008107 Liver Diseases Acetaminophen 5.9712969438 11587558 19784758 19460945 19014921 16611625 12587719 16610002
MESH:D008107 Liver Diseases Carbon Tetrachloride 5.9715720792 16246199 15830285 16964402 17285989
MESH:D008107 Liver Diseases Phenobarbital 5.9719363144
MESH:D017093 Liver Failure Carbon Tetrachloride 3.8615123358
MESH:D017114 Liver Failure, Acute Acetaminophen 14.7116871587 17185352
MESH:D017114 Liver Failure, Acute Carbon Tetrachloride 14.7116899240 14706259
MESH:D017114 Liver Failure, Acute Dimethylnitrosamine 14.7117457977
MESH:D008113 Liver Neoplasms Benzo(a)pyrene 23.8120195826 21137059
MESH:D008113 Liver Neoplasms Carbon Tetrachloride 23.8119294768
MESH:D008113 Liver Neoplasms Diethylstilbestrol 23.8116712894 15890375
MESH:D008113 Liver Neoplasms Dimethylnitrosamine 23.8115890375 3113478
MESH:D008113 Liver Neoplasms Phenobarbital 23.8121047994 19812893 8742319 19073162 15975961 19482888
MESH:D008113 Liver Neoplasms pirinixic acid 23.8115890375 16377806 20007298
MESH:D008113 Liver Neoplasms resveratrol 23.8119812893 19321006 19073162 20405173
MESH:D008113 Liver Neoplasms Tetrachlorodibenzodioxin 23.8116984957
MESH:D008114 Liver Neoplasms, Experimental Carbon Tetrachloride 16.6012014681 15583823
MESH:D008114 Liver Neoplasms, Experimental Dimethylnitrosamine 16.6015603536 1848544 6150874
MESH:D008114 Liver Neoplasms, Experimental Doxorubicin 16.6017085340 16842330
MESH:D008114 Liver Neoplasms, Experimental Phenobarbital 16.601399818 18308698 2563599 17172636 6150874
MESH:D008114 Liver Neoplasms, Experimental Tetrachlorodibenzodioxin 16.6012151625
MESH:D008133 Long QT Syndrome olanzapine 4.4920210726
MESH:D008171 Lung Diseases Mustard Gas 3.2418702808 18161513
MESH:D017563 Lung Diseases, Interstitial Valproic Acid 3.9517228818
MESH:D008175 Lung Neoplasms Benzo(a)pyrene 8.0118520028 20135361 18569708 20064080 20464547 6695378 18816296 17053015 20869020
MESH:D008175 Lung Neoplasms Dimethylnitrosamine 8.0116061637 11884234 19555203
MESH:D008175 Lung Neoplasms Doxorubicin 8.0117418594 6189445
MESH:D008175 Lung Neoplasms Ethylnitrosourea 8.016695378 16271038 16019985 17703301
MESH:D008175 Lung Neoplasms Mustard Gas 8.013148597 8781369
MESH:D008175 Lung Neoplasms Tetrachlorodibenzodioxin 8.0119555203 11884234
MESH:D008181 Lupus Nephritis Diethylstilbestrol 4.8415166399
MESH:D008223 Lymphoma Diethylstilbestrol 11.4315700306
MESH:D008223 Lymphoma Doxorubicin 11.4316098063
MESH:D008223 Lymphoma Ethylnitrosourea 11.4315790496
MESH:D016393 Lymphoma, B-Cell resveratrol 4.0117088997
MESH:D008228 Lymphoma, Non-Hodgkin Doxorubicin 8.0517654614
MESH:D008228 Lymphoma, Non-Hodgkin resveratrol 8.0514749477
MESH:D016399 Lymphoma, T-Cell Doxorubicin 10.6815621674
MESH:D016399 Lymphoma, T-Cell Ethylnitrosourea 10.6815375218
MESH:D052801 Male Urogenital Diseases Diethylstilbestrol 5.2016002989
MESH:D015674 Mammary Neoplasms, Animal resveratrol 3.9415688416
MESH:D008325 Mammary Neoplasms, Experimental Doxorubicin 9.0315458769
MESH:D008325 Mammary Neoplasms, Experimental Ethylnitrosourea 9.0310838139 10767621 18041768
MESH:D008325 Mammary Neoplasms, Experimental resveratrol 9.038985016 11606380
MESH:D008545 Melanoma Doxorubicin 3.4016827129
MESH:D008545 Melanoma resveratrol 3.4017992120
MESH:D008546 Melanoma, Experimental Acetaminophen 3.2619513568
MESH:D008579 Meningioma Ethylnitrosourea 5.6717943659
MESH:D001523 Mental Disorders Clozapine 21.2616856516
MESH:D001523 Mental Disorders Fluoxetine 21.2616856516
MESH:D001523 Mental Disorders Haloperidol 21.2616856516
MESH:D001523 Mental Disorders olanzapine 21.2616856516
MESH:D001523 Mental Disorders Sulpiride 21.2616856516
MESH:D008654 Mesothelioma Doxorubicin 2.9317638057
MESH:D008659 Metabolic Diseases olanzapine 10.0819142110
MESH:D008659 Metabolic Diseases resveratrol 10.0817112576
MESH:D024821 Metabolic Syndrome X Clozapine 4.1619142101
MESH:D053842 Microsatellite Instability Methylnitronitrosoguanidine 5.5817671175
MESH:D008881 Migraine Disorders Valproic Acid 2.9718803445 18765137
MESH:D028361 Mitochondrial Diseases Doxorubicin 4.2215792986
MESH:D009062 Mouth Neoplasms Benzo(a)pyrene 2.9616381670
MESH:D052016 Mucositis Doxorubicin 4.4817415656
MESH:D009101 Multiple Myeloma resveratrol 3.2516490592 14749477 16267019 17935668 17164350 17049120
MESH:D009134 Muscular Atrophy, Spinal resveratrol 4.5617962980
MESH:D009135 Muscular Diseases pirinixic acid 3.2016239165
MESH:D009139 Musculoskeletal Abnormalities Valproic Acid 3.758888407
MESH:D009190 Myelodysplastic Syndromes Valproic Acid 2.9817596541
MESH:D009203 Myocardial Infarction Doxorubicin 12.5315857846 19429709
MESH:D009203 Myocardial Infarction Lithium 12.5316288908
MESH:D009203 Myocardial Infarction pirinixic acid 12.5319151258
MESH:D009203 Myocardial Infarction resveratrol 12.5317188708 16317513 16456233 17125593 17015251 16525036
MESH:D017202 Myocardial Ischemia resveratrol 8.2017125593 17015251
MESH:D017202 Myocardial Ischemia Tetrachlorodibenzodioxin 8.2012213967
MESH:D015428 Myocardial Reperfusion Injury pirinixic acid 2.7116411023
MESH:D009205 Myocarditis resveratrol 4.4517322642
MESH:D020191 Myoclonic Epilepsies, Progressive Phenobarbital 4.1617484760
MESH:D009207 Myoclonus Fluoxetine 5.578041377
MESH:D009336 Necrosis Trinitrotoluene 4.4618551238
MESH:D009362 Neoplasm Metastasis Doxorubicin 2.8318259882
MESH:D009369 Neoplasms Benzo(a)pyrene 7.3311141357
MESH:D009369 Neoplasms Diethylstilbestrol 7.3315313581
MESH:D009369 Neoplasms pirinixic acid 7.3317405874
MESH:D009374 Neoplasms, Experimental Ethylnitrosourea 8.4916707424
MESH:D009374 Neoplasms, Experimental resveratrol 8.498985016
MESH:D009401 Nephrosis Doxorubicin 4.4616899518 16636307
MESH:D009404 Nephrotic Syndrome Doxorubicin 3.7415640375 16889571
MESH:D009421 Nervous System Malformations Diethylstilbestrol 8.6611399458
MESH:D009421 Nervous System Malformations Tetrachlorodibenzodioxin 8.6614600291
MESH:D009436 Neural Tube Defects Valproic Acid 2.9316359493 8888407
MESH:D009442 Neurilemmoma Ethylnitrosourea 5.1017160924 16003739 16651423
MESH:D009447 Neuroblastoma Doxorubicin 3.1015555623
MESH:D019636 Neurodegenerative Diseases Acetaminophen 7.5218514411
MESH:D019636 Neurodegenerative Diseases resveratrol 7.5217652729
MESH:D020078 Neurogenic Inflammation resveratrol 4.1117929310
MESH:D009503 Neutropenia Mustard Gas 3.697688884 16761898
MESH:D009765 Obesity Clozapine 10.0418515891 19142110
MESH:D009765 Obesity Dietary Fats 10.0417217161 11836018 20518802 20132043 18457598 16723640 18674790 19632207 21332399
MESH:D009765 Obesity olanzapine 10.0418515891
MESH:D009765 Obesity pirinixic acid 10.0420558911
MESH:D009771 Obsessive-Compulsive Disorder Fluoxetine 5.1620418887
MESH:D009784 Occupational Diseases Trinitrotoluene 4.0712819281 14694615 17852074
MESH:D009837 Oligodendroglioma Ethylnitrosourea 5.6717160924
MESH:D010018 Osteomalacia Phenobarbital 4.0517016548
MESH:D015663 Osteoporosis, Postmenopausal resveratrol 3.9717513867
MESH:D012516 Osteosarcoma Doxorubicin 3.8715930896
MESH:D010146 Pain Acetaminophen 6.2916870215
MESH:D010146 Pain Fluoxetine 6.2912798668
MESH:D010190 Pancreatic Neoplasms Phenobarbital 2.3816965848
MESH:D016584 Panic Disorder Ethinyl Estradiol 3.4011578682
MESH:D010382 Peliosis Hepatis Tetrachlorodibenzodioxin 3.9312520081
MESH:D003557 Phyllodes Tumor Doxorubicin 4.8417983394
MESH:D020774 Pick Disease of the Brain Fluoxetine 5.698041377
MESH:D010900 Pituitary Diseases Diethylstilbestrol 4.8514722030
MESH:D010911 Pituitary Neoplasms Diethylstilbestrol 4.3716977796 15687265
MESH:D010997 Pleural Neoplasms Doxorubicin 4.8417638057
MESH:D011041 Poisoning Mustard Gas 3.5115727166
MESH:D017119 Porphyria Cutanea Tarda Tetrachlorodibenzodioxin 3.2618163543
MESH:D011230 Precancerous Conditions Phenobarbital 3.362563599
MESH:D011297 Prenatal Exposure Delayed Effects Diethylstilbestrol 27.1417184923
MESH:D011297 Prenatal Exposure Delayed Effects resveratrol 27.1416679765
MESH:D011297 Prenatal Exposure Delayed Effects Tetrachlorodibenzodioxin 27.1411118676 11896295 11399792 11222880
MESH:D011297 Prenatal Exposure Delayed Effects Valproic Acid 27.1420603192
MESH:D011297 Prenatal Exposure Delayed Effects vinclozolin 27.1419015723 18220299 18042343
MESH:D011350 Proctocolitis Acetic Acid 7.1111561086
MESH:D011469 Prostatic Diseases vinclozolin 4.6218220299
MESH:D011471 Prostatic Neoplasms Benzo(a)pyrene 2.1717292933
MESH:D011471 Prostatic Neoplasms Diethylstilbestrol 2.1717136230 15846301 15046698
MESH:D011471 Prostatic Neoplasms Doxorubicin 2.1716868541 15897917 16888761 18437689 15749863 16729912
MESH:D011471 Prostatic Neoplasms resveratrol 2.1717804756 17675339 16731767 17636462 15767336 17718901
MESH:D011472 Prostatitis vinclozolin 4.6218629315
MESH:D011537 Pruritus Ethinyl Estradiol 8.4916919318 15861022
MESH:D011537 Pruritus Mustard Gas 8.4918058305
MESH:D019310 Pseudolymphoma Phenobarbital 11.1412752131
MESH:D019310 Pseudolymphoma Valproic Acid 11.1412752131 11422049
MESH:D011595 Psychomotor Agitation Haloperidol 10.8011575062
MESH:D011595 Psychomotor Agitation olanzapine 10.8018685284
MESH:D011618 Psychotic Disorders Clozapine 8.4215331141
MESH:D011618 Psychotic Disorders Haloperidol 8.4211575062
MESH:D011658 Pulmonary Fibrosis Mustard Gas 2.8117894541 17720292 17266442 17620002 10334151
MESH:D051437 Renal Insufficiency Doxorubicin 3.9217922066
MESH:D051436 Renal Insufficiency, Chronic resveratrol 5.2716325855
MESH:D015427 Reperfusion Injury pirinixic acid 6.0619058328
MESH:D015427 Reperfusion Injury resveratrol 6.0616317513 17520802 17058453 16314181 15827377
MESH:D015619 Respiratory System Abnormalities Tetrachlorodibenzodioxin 3.5418990726
MESH:D012208 Rhabdomyosarcoma Valproic Acid 3.8919155313
MESH:D012509 Sarcoma Doxorubicin 3.7217203757 17710206 15675481 16767912 18313854 15625365
MESH:D012512 Sarcoma, Ewing's Doxorubicin 3.9516326096 14601052
MESH:D012514 Sarcoma, Kaposi Doxorubicin 4.4817846226
MESH:D012559 Schizophrenia marker/mechanism 11126396 19110320 14708030
MESH:D012559 Schizophrenia Clozapine 10.0618855531 18806925 20168265 11763009 16141801 19369910 17667964 11151749 20107430 20452607 20580759 17123785 17726453 20521320 20521326
MESH:D012559 Schizophrenia Haloperidol 10.0619369910 20107430 18513383 1830565
MESH:D012559 Schizophrenia Methionine 10.0615737665
MESH:D012559 Schizophrenia olanzapine 10.0617726453 20107430 20521326
MESH:D012559 Schizophrenia Valproic Acid 10.0619110320 15737665
MESH:D012640 Seizures Lithium 12.4619660546
MESH:D012640 Seizures Phenobarbital 12.463137016 4039156 11442880 16876388
MESH:D012640 Seizures Trinitrotoluene 12.4618551238
MESH:D012640 Seizures Valproic Acid 12.4611044598 15475178 1511512 14763951 11738929 16876388 3137016 17978042
MESH:D003294 Seizures, Febrile Phenobarbital 4.516407741
MESH:D020230 Serotonin Syndrome Fluoxetine 5.588704074
MESH:D012871 Skin Diseases Mustard Gas 2.6316961503 12880345 15451306
MESH:D012878 Skin Neoplasms Benzo(a)pyrene 12.3519755658 10029692
MESH:D012878 Skin Neoplasms Doxorubicin 12.3515692506
MESH:D012878 Skin Neoplasms resveratrol 12.358985016 15837718
MESH:D012878 Skin Neoplasms Tetrachlorodibenzodioxin 12.3516192470
MESH:D012983 Soft Tissue Neoplasms Doxorubicin 4.2617203757 15625365 16767912
MESH:D013088 Spermatocele Diethylstilbestrol 10.6616002989 16709447
MESH:D013088 Spermatocele Ethinyl Estradiol 10.6616709447
MESH:D016135 Spinal Dysraphism Valproic Acid 3.5419490988
MESH:D013158 Splenic Diseases Dimethylnitrosamine 4.9512587719
MESH:D013163 Splenomegaly Trinitrotoluene 4.9015817613
MESH:D013226 Status Epilepticus Lithium 11.6119430551 19951488 19570321
MESH:D013226 Status Epilepticus Valproic Acid 11.6112833885
MESH:D013274 Stomach Neoplasms Benzo(a)pyrene 2.512093021 20155912
MESH:D013274 Stomach Neoplasms Dimethylnitrosamine 2.5116033868
MESH:D013276 Stomach Ulcer Acetic Acid 5.0319188055
OMIM:601367 STROKE, ISCHEMIC resveratrol 4.2116321402
MESH:D017180 Tachycardia, Ventricular Haloperidol 9.9720210726
MESH:D017180 Tachycardia, Ventricular olanzapine 9.9720210726
MESH:D019851 Thrombophilia Ethinyl Estradiol 3.3311994571
MESH:D013927 Thrombosis Ethinyl Estradiol 2.8915669648
MESH:D013953 Thymus Neoplasms Ethylnitrosourea 4.8515790496
MESH:D013959 Thyroid Diseases Tetrachlorodibenzodioxin 3.5912697716
MESH:D013964 Thyroid Neoplasms Doxorubicin 6.5516010429 17909728
MESH:D013964 Thyroid Neoplasms Phenobarbital 6.551399818
MESH:D014062 Tongue Neoplasms resveratrol 3.9416227395
MESH:D014178 Translocation, Genetic Valproic Acid 4.9217262798
MESH:D020194 Unverricht-Lundborg Syndrome Valproic Acid 4.213119515
MESH:D001749 Urinary Bladder Neoplasms Benzo(a)pyrene 7.6617053015
MESH:D001749 Urinary Bladder Neoplasms Diethylstilbestrol 7.6616452187 17306315 16712894
MESH:D001749 Urinary Bladder Neoplasms Doxorubicin 7.6617653716
MESH:D014564 Urogenital Abnormalities Valproic Acid 4.348888407
MESH:D014581 Urticaria Acetaminophen 2.6910982225
MESH:D002583 Uterine Cervical Neoplasms Diethylstilbestrol 8.7716175088
MESH:D002583 Uterine Cervical Neoplasms resveratrol 8.7717473185
MESH:D014591 Uterine Diseases Diethylstilbestrol 4.8514652134
MESH:D014594 Uterine Neoplasms Diethylstilbestrol 14.3616690809 15809267
MESH:D014594 Uterine Neoplasms Ethinyl Estradiol 14.3614692618
MESH:D014594 Uterine Neoplasms resveratrol 14.3617044934
MESH:D014625 Vaginal Neoplasms Diethylstilbestrol 4.1316513791 16002989
MESH:D054079 Vascular Malformations Tetrachlorodibenzodioxin 4.2812125929
MESH:D020246 Venous Thrombosis Ethinyl Estradiol 3.2614671159 15869587
MESH:D018487 Ventricular Dysfunction, Left Doxorubicin 9.3317678736 17638931 17334414 16364871
MESH:D018487 Ventricular Dysfunction, Left resveratrol 9.3317488730
MESH:D019282 Wasting Syndrome Tetrachlorodibenzodioxin 3.9315886252
MESH:D015430 Weight Gain Clozapine 14.9216402076 20107430 16141801 17502770 20564506 20521320
MESH:D015430 Weight Gain Dietary Fats 14.9216723640
MESH:D015430 Weight Gain olanzapine 14.9220107430 17933447 19434072
MESH:D015431 Weight Loss Clozapine 4.7717933447
Pathway ID Pathway Name
KEGG:04512 ECM-receptor interaction
KEGG:04510 Focal adhesion
Pharmacogenomics Knowledge Base Top
  • PharmGKB Accession:PA34323
    • No data
    Releated disease ID Related disease Name
    PA445201Otosclerosis
    PA447199Bipolar Disorder
    PA447216Schizophrenia
    PA446714Neoplasm, Residual
    PA446155Precursor Cell Lymphoblastic Leukemia-Lymphoma
    PA445201Otosclerosis
    PA447216Schizophrenia
    PA444987Multiple Sclerosis
    Releated drug ID Related drug Name
    PA152241909PP2
    Drug Bank Top

    Simple Query:


      (e.g. CHD8)

    Syndromic Genes

    Non-syndromic Genes

    AutismKB Statistics

    • Studies: 1,036
    • Genes: 1,379
    • CNVs/SVs: 5,420
    • SNVs/Indels: 11,669
    • de novo Mutations: 5,669
    • Mosaics: 789
    • Linkage Regions: 172
    • Paper Collected: 6/30/2018
    • Last Update: 8/26/2018


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