Annotation Detail for KCNK12
Basic Information
Top
| Desease Name |
|---|
| vitiligo |
| IMMUNE |
| Chemical ID |
Chemical Name |
Interaction |
Interaction Action |
Publication |
|---|
| D000638 |
Amiodarone |
Amiodarone results in increased expression of KCNK12 mRNA | increases expression | 19774075
|
| C006632 |
arsenic trioxide |
arsenic trioxide results in increased expression of KCNK12 mRNA | increases expression | 20458559
|
| D005419 |
Flavonoids |
Flavonoids results in increased expression of KCNK12 mRNA | increases expression | 18035473
|
| Disease ID |
Disease Name |
Direct Evidence |
Inference Chemical Name |
Inference Score |
Publication |
|---|
| MESH:D000230 |
Adenocarcinoma |
|
arsenic trioxide |
2.36 | 11798837 19825857 |
| MESH:D001145 |
Arrhythmias, Cardiac |
|
Amiodarone |
4.25 | 18218290 18057881 20041841 |
| MESH:D001281 |
Atrial Fibrillation |
|
Amiodarone |
4.23 | 19698954 18651412 |
| MESH:D001778 |
Blood Coagulation Disorders |
|
Amiodarone |
10.93 | 19483382 |
| MESH:D001778 |
Blood Coagulation Disorders |
|
arsenic trioxide |
10.93 | 16206674 |
| MESH:D002051 |
Burkitt Lymphoma |
|
arsenic trioxide |
4.86 | 11589617 |
| MESH:D006528 |
Carcinoma, Hepatocellular |
|
arsenic trioxide |
1.98 | 11135700 16217749 15073043 14691202 15553829 |
| MESH:D002291 |
Carcinoma, Papillary |
|
arsenic trioxide |
5.74 | 19014326 |
| MESH:D018288 |
Carcinoma, Small Cell |
|
arsenic trioxide |
4.57 | 12490120 |
| MESH:D002311 |
Cardiomyopathy, Dilated |
|
Amiodarone |
3.01 | 15710769 19225199 |
| MESH:D002341 |
Carotid Artery Thrombosis |
|
Amiodarone |
5.83 | 18974383 |
| MESH:D015179 |
Colorectal Neoplasms |
|
arsenic trioxide |
1.87 | 20501625 |
| MESH:D023903 |
Coronary Restenosis |
|
arsenic trioxide |
4.77 | 12609071 |
| MESH:D019465 |
Craniofacial Abnormalities |
|
arsenic trioxide |
1.89 | 10525206 |
| MESH:D016757 |
Death, Sudden, Cardiac |
|
arsenic trioxide |
4.63 | 15213294 |
| MESH:D056486 |
Drug-Induced Liver Injury |
|
Amiodarone |
2.48 | 18218290 15265979 |
| MESH:D004938 |
Esophageal Neoplasms |
|
arsenic trioxide |
2.39 | 12903497 |
| MESH:D005234 |
Fatty Liver |
|
Amiodarone |
9.65 | 14986274 |
| MESH:D005234 |
Fatty Liver |
|
arsenic trioxide |
9.65 | 15073043 |
| MESH:D005706 |
Gallbladder Neoplasms |
|
arsenic trioxide |
4.85 | 16904648 |
| MESH:D006529 |
Hepatomegaly |
|
Amiodarone |
4.40 | 15265979 |
| MESH:D006937 |
Hypercholesterolemia |
|
Amiodarone |
4.36 | 8137927 9751232 |
| MESH:D007037 |
Hypothyroidism |
|
Amiodarone |
5.17 | 18020914 17991464 |
| MESH:D007249 |
Inflammation |
|
Flavonoids |
2.84 | 17296493 |
| MESH:D007938 |
Leukemia |
|
arsenic trioxide |
3.01 | 15070760 |
| MESH:D015459 |
Leukemia-Lymphoma, Adult T-Cell |
|
arsenic trioxide |
4.28 | 12560223 17077332 |
| MESH:D007948 |
Leukemia, Monocytic, Acute |
|
arsenic trioxide |
5.05 | 16972261 |
| MESH:D015464 |
Leukemia, Myelogenous, Chronic, BCR-ABL Positive |
|
arsenic trioxide |
3.75 | 14633726 |
| MESH:D007951 |
Leukemia, Myeloid |
|
arsenic trioxide |
4.24 | 19077051 |
| MESH:D015470 |
Leukemia, Myeloid, Acute |
|
arsenic trioxide |
2.19 | 16467208 20471514 16968895 17050201 19850784 |
| MESH:D015473 |
Leukemia, Promyelocytic, Acute |
|
arsenic trioxide |
3.48 | 19075265 15336539 19035177 16330433 17649720 17869043 12712474 15622746 17107899 19225113 17712046 12679006 16112521 16966277 19642359 15748426 11468182 16331271 9834237 17217047 15213294 11161223 16891316 16823087 12018890 |
| MESH:D015458 |
Leukemia, T-Cell |
|
arsenic trioxide |
4.94 | 16882451 |
| MESH:D008064 |
Lipidoses |
|
Amiodarone |
3.82 | 17567588 15342952 |
| MESH:D008113 |
Liver Neoplasms |
|
arsenic trioxide |
2.47 | 14682389 |
| MESH:D008114 |
Liver Neoplasms, Experimental |
|
arsenic trioxide |
2.98 | 20377131 |
| MESH:D008133 |
Long QT Syndrome |
|
Amiodarone |
9.36 | 15350150 17391786 11989578 |
| MESH:D008133 |
Long QT Syndrome |
|
arsenic trioxide |
9.36 | 15213294 |
| MESH:D008171 |
Lung Diseases |
|
Amiodarone |
3.65 | 12587719 |
| MESH:D017563 |
Lung Diseases, Interstitial |
|
Amiodarone |
5.34 | 18516814 |
| MESH:D008175 |
Lung Neoplasms |
|
arsenic trioxide |
1.87 | 11798837 19825857 |
| MESH:D009101 |
Multiple Myeloma |
|
arsenic trioxide |
3.41 | 19549372 19417148 15949261 11468182 14977855 |
| MESH:D009181 |
Mycoses |
|
Amiodarone |
5.77 | 12754197 17974566 |
| MESH:D009182 |
Mycosis Fungoides |
|
arsenic trioxide |
5.54 | 18349030 |
| MESH:D009190 |
Myelodysplastic Syndromes |
|
arsenic trioxide |
3.36 | 16882451 16105982 |
| MESH:D009361 |
Neoplasm Invasiveness |
|
arsenic trioxide |
4.54 | 16624393 |
| MESH:D009436 |
Neural Tube Defects |
|
arsenic trioxide |
3.38 | 10525206 |
| MESH:D010051 |
Ovarian Neoplasms |
|
arsenic trioxide |
2.51 | 16624393 19769630 12452020 |
| MESH:D010190 |
Pancreatic Neoplasms |
|
arsenic trioxide |
2.64 | 15580305 |
| MESH:D010235 |
Paraganglioma |
|
arsenic trioxide |
4.69 | 19927285 |
| MESH:D011471 |
Prostatic Neoplasms |
|
arsenic trioxide |
3.20 | 19131511 |
| MESH:D011658 |
Pulmonary Fibrosis |
|
Amiodarone |
2.98 | 12490602 12832656 11597910 |
| MESH:D012512 |
Sarcoma, Ewing's |
|
arsenic trioxide |
4.54 | 16646077 |
| OMIM:609620 |
SHORT QT SYNDROME 1 |
|
Amiodarone |
5.83 | 18724381 |
| MESH:D013274 |
Stomach Neoplasms |
|
arsenic trioxide |
1.86 | 17007042 |
| MESH:D013276 |
Stomach Ulcer |
|
Amiodarone |
3.79 | 18087811 |
| MESH:D013610 |
Tachycardia |
|
Amiodarone |
4.87 | 11238279 |
| MESH:D017180 |
Tachycardia, Ventricular |
|
Amiodarone |
4.77 | 19225199 |
| MESH:D013959 |
Thyroid Diseases |
|
Amiodarone |
5.62 | 19731979 |
| MESH:D013964 |
Thyroid Neoplasms |
|
arsenic trioxide |
3.43 | 19014326 |
| MESH:D013971 |
Thyrotoxicosis |
|
Amiodarone |
5.51 | 19584973 18020914 |
| MESH:D016171 |
Torsades de Pointes |
|
Amiodarone |
12.87 | 11989578 17467628 |
| MESH:D016171 |
Torsades de Pointes |
|
arsenic trioxide |
12.87 | 15213294 |
| MESH:D001749 |
Urinary Bladder Neoplasms |
|
arsenic trioxide |
2.61 | 12845720 20435036 12973940 11780464 |
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