AutismKB 2.0

Annotation Detail for SLC2A4RG


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Basic Information Top
Gene Symbol:SLC2A4RG ( GEF,HDBP1,Si-1-2,Si-1-2-19 )
Gene Full Name: SLC2A4 regulator
Band: 20q13.33
Quick LinksEntrez ID:56731; OMIM: 609493; Uniprot ID:S2A4R_HUMAN; ENSEMBL ID: ENSG00000125520; HGNC ID: 15930
Relate to Another Database: SFARIGene; denovo-db
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Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C061133 Am 80 Am 80 results in increased expression of SLC2A4RG mRNAincreases expression 17229644
D001564 Benzo(a)pyrene Benzo(a)pyrene results in decreased expression of SLC2A4RG mRNAdecreases expression 20106945
D016572 Cyclosporine Cyclosporine results in decreased expression of SLC2A4RG mRNAdecreases expression 20106945
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000230 Adenocarcinoma Benzo(a)pyrene 2.0620127859 20464547
MESH:D000236 Adenoma Benzo(a)pyrene 2.886695378
MESH:D017544 Aortic Aneurysm, Abdominal Benzo(a)pyrene 4.7319183758
MESH:D001172 Arthritis, Rheumatoid Am 80 3.8316819260
MESH:D050197 Atherosclerosis Am 80 4.5716484594
MESH:D001943 Breast Neoplasms Benzo(a)pyrene 1.9920146248 17474063
MESH:D002294 Carcinoma, Squamous Cell Benzo(a)pyrene 2.1420419170
MESH:D002471 Cell Transformation, Neoplastic Cyclosporine 2.8212371664
MESH:D002779 Cholestasis Cyclosporine 3.2419486331
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Am 80 5.6716819260
MESH:D004938 Esophageal Neoplasms Benzo(a)pyrene 2.0916530937
MESH:D005234 Fatty Liver Cyclosporine 3.3419224547
MESH:D005355 Fibrosis Cyclosporine 3.7912639820 12168785
MESH:D005885 Gingival Hyperplasia Cyclosporine 4.968708960
MESH:D006330 Heart Defects, Congenital Benzo(a)pyrene 2.8520471113
MESH:D006457 Hemoglobinuria, Paroxysmal Cyclosporine 5.1615720958
MESH:D006973 Hypertension Cyclosporine 2.2310903974
MESH:D007638 Keratoconjunctivitis Sicca Cyclosporine 5.3115604871
MESH:D007674 Kidney Diseases Cyclosporine 2.568314463 10903974 18776723
MESH:D007680 Kidney Neoplasms Cyclosporine 3.1212371664
MESH:D015473 Leukemia, Promyelocytic, Acute Am 80 4.9116531727 16819260
MESH:D008113 Liver Neoplasms Benzo(a)pyrene 2.1721137059 20195826
MESH:D008175 Lung Neoplasms Benzo(a)pyrene 1.5720064080 20464547 18569708 17053015 20135361 18520028 18816296 6695378 20869020
MESH:D008664 Metal Metabolism, Inborn Errors Cyclosporine 5.6516801185
MESH:D009062 Mouth Neoplasms Benzo(a)pyrene 3.5316381670
MESH:D009101 Multiple Myeloma Am 80 4.8417229644
MESH:D009369 Neoplasms Benzo(a)pyrene 2.3511141357
MESH:D009402 Nephrosis, Lipoid Cyclosporine 5.3117954296
MESH:D009404 Nephrotic Syndrome Cyclosporine 3.7019348381 18481113
MESH:D011230 Precancerous Conditions Cyclosporine 3.6412371664
MESH:D011471 Prostatic Neoplasms Am 80 3.6116289102
MESH:D011471 Prostatic Neoplasms Benzo(a)pyrene 3.6117292933
MESH:D011565 Psoriasis Am 80 6.5516819260
MESH:D011565 Psoriasis Cyclosporine 6.5516882103
MESH:D012878 Skin Neoplasms Benzo(a)pyrene 2.5419755658 10029692
MESH:D013274 Stomach Neoplasms Benzo(a)pyrene 1.562093021 20155912
MESH:D001749 Urinary Bladder Neoplasms Benzo(a)pyrene 2.3117053015
MESH:D014605 Uveitis Cyclosporine 4.851336536
MESH:D014985 Xerophthalmia Cyclosporine 5.3117120751
No data
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Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018