AutismKB 2.0

Annotation Detail for ZC3HAV1


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:ZC3HAV1 ( DKFZp686F2052,DKFZp686H1869,DKFZp686O19171,FLB6421,FLJ13288,MGC48898,PARP13,ZAP,ZC3H2,ZC3HDC2 )
Gene Full Name: zinc finger CCCH-type, antiviral 1
Band: 7q34
Quick LinksEntrez ID:56829; OMIM: 607312; Uniprot ID:ZCCHV_HUMAN; ENSEMBL ID: ENSG00000105939; HGNC ID: 23721
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
Related Diseases/Disorders Top
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C026114 2-xylene 2-xylene results in increased expression of ZC3HAV1 mRNAincreases expression 20359517
D000638 Amiodarone Amiodarone results in increased expression of ZC3HAV1 mRNAincreases expression 19774075
D000643 Ammonium Chloride Ammonium Chloride affects the expression of ZC3HAV1 mRNAaffects expression 16483693
D001554 Benzene Benzene results in increased expression of ZC3HAV1 mRNAincreases expression 20359517
D019324 beta-Naphthoflavone [Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of ZC3HAV1 mRNAaffects cotreatment|increases expression 18164116
D016572 Cyclosporine Cyclosporine results in decreased expression of ZC3HAV1 mRNAdecreases expression 20106945
D004052 Diethylnitrosamine [Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of ZC3HAV1 mRNAaffects cotreatment|increases expression 18164116
D004997 Ethinyl Estradiol [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of ZC3HAV1 mRNAaffects cotreatment|increases expression 17942748
C004912 ethylbenzene ethylbenzene results in increased expression of ZC3HAV1 mRNAincreases expression 20359517
D007213 Indomethacin Indomethacin results in increased expression of ZC3HAV1 mRNAincreases expression 16984733
C051890 irinotecan irinotecan analog results in decreased expression of ZC3HAV1 mRNAdecreases expression 18927307
D008752 Methylene Chloride Methylene Chloride results in increased expression of ZC3HAV1 mRNAincreases expression 20359517
D012643 Selenium Selenium results in decreased expression of ZC3HAV1 mRNAdecreases expression 19244175
D013749 Tetrachlorodibenzodioxin [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of ZC3HAV1 mRNAaffects cotreatment|increases expression 17942748
D014050 Toluene Toluene results in increased expression of ZC3HAV1 mRNAincreases expression 20359517
D014241 Trichloroethylene Trichloroethylene results in increased expression of ZC3HAV1 mRNAincreases expression 20359517
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000014 Abnormalities, Drug-Induced Tetrachlorodibenzodioxin 2.8714514962 11752688 15322242
MESH:D000138 Acidosis Ammonium Chloride 3.5818287403
MESH:D000152 Acne Vulgaris Ethinyl Estradiol 3.9717505938
MESH:D000230 Adenocarcinoma Ethinyl Estradiol 4.4714692618
MESH:D000230 Adenocarcinoma Indomethacin 4.4716537180
MESH:D000236 Adenoma beta-Naphthoflavone 11.3319389873
MESH:D000236 Adenoma Diethylnitrosamine 11.3310737359 6695378
MESH:D000236 Adenoma Indomethacin 11.3311497255
MESH:D018248 Adenoma, Liver Cell Diethylnitrosamine 10.1218056438 19052882 17162532 16434500 17620307 19061943
MESH:D018248 Adenoma, Liver Cell Tetrachlorodibenzodioxin 10.1216835633
MESH:D016301 Alveolar Bone Loss Indomethacin 5.4017225004
MESH:D000544 Alzheimer Disease Indomethacin 2.7017627676 15579461
MESH:D000740 Anemia Tetrachlorodibenzodioxin 2.9511748828
MESH:D000741 Anemia, Aplastic Benzene 4.3711369114 17661222 14761424
MESH:D001014 Aortic Aneurysm Indomethacin 4.8610231640
MESH:D017544 Aortic Aneurysm, Abdominal Indomethacin 4.8810388637
MESH:D001145 Arrhythmias, Cardiac Amiodarone 3.8018057881 18218290 20041841
MESH:D001161 Arteriosclerosis Ethinyl Estradiol 3.4811256880
MESH:D018771 Arthralgia Indomethacin 5.202160914
MESH:D001169 Arthritis, Experimental Ethinyl Estradiol 2.6615885639
MESH:D001172 Arthritis, Rheumatoid Indomethacin 2.8211248219
MESH:D001281 Atrial Fibrillation Amiodarone 3.9019698954 18651412
MESH:D001477 Bartter Syndrome Indomethacin 5.0010684365
MESH:D001778 Blood Coagulation Disorders Amiodarone 9.0619483382
MESH:D001778 Blood Coagulation Disorders Tetrachlorodibenzodioxin 9.0612125929
MESH:D001836 Body Weight Changes 2-xylene 12.217457028
MESH:D001836 Body Weight Changes Tetrachlorodibenzodioxin 12.2115340226
MESH:D001848 Bone Diseases, Developmental Tetrachlorodibenzodioxin 2.7615746008
MESH:D001855 Bone Marrow Diseases Benzene 5.2616183116
MESH:D001929 Brain Edema Indomethacin 5.0611481608
MESH:D002545 Brain Ischemia Indomethacin 4.4412524144
MESH:D001943 Breast Neoplasms Benzene 2.9811921183 17162533
MESH:D001943 Breast Neoplasms Diethylnitrosamine 2.9817474063
MESH:D001943 Breast Neoplasms Indomethacin 2.9817401462
MESH:D001943 Breast Neoplasms Methylene Chloride 2.9815986119
MESH:D001943 Breast Neoplasms Tetrachlorodibenzodioxin 2.9820435547
MESH:D001943 Breast Neoplasms Trichloroethylene 2.9815986119
MESH:D002056 Burns Indomethacin 4.7210459503
MESH:D002100 Cachexia Indomethacin 5.0215141370 16537180 15625704 11239499
MESH:D002277 Carcinoma Tetrachlorodibenzodioxin 2.8016835633
MESH:D006528 Carcinoma, Hepatocellular Diethylnitrosamine 3.2420514400 19519916 16540662 18056438 20512989 3084413 19208518 20432363 16830150 3581430 10672840 17761372 16502159 18210153 17055752 18494052 20727157 17138121 16698587 18393292 16569478 20007298 18978308 19701751 20214788 16878318 16328049 18506893 16935385 20935162 20524982 19107877 20101231 17978847 10737359 17173139 17162532 16807293 18665156 20084675 19335982 19394651 19539802 19418558 19383236 17428255 16288022 19822196 18971187 18788625 19171122 19052882 18785209 19919837 16779866 11831363 16681979 18691550 21159647
MESH:D006528 Carcinoma, Hepatocellular Indomethacin 3.2416391822
MESH:D018827 Carcinoma, Lewis Lung Indomethacin 4.7511053908
MESH:D018276 Carcinoma, Medullary Indomethacin 5.3711352223 14736730 18791128
MESH:D002292 Carcinoma, Renal Cell Indomethacin 3.3717341418
MESH:D002294 Carcinoma, Squamous Cell Indomethacin 2.8512636206 15482327
MESH:D006332 Cardiomegaly Tetrachlorodibenzodioxin 2.3718850075 18670907 16120746
MESH:D002311 Cardiomyopathy, Dilated Amiodarone 2.8915710769 19225199
MESH:D002341 Carotid Artery Thrombosis Amiodarone 5.1018974383
MESH:D002471 Cell Transformation, Neoplastic Cyclosporine 6.6112371664
MESH:D002471 Cell Transformation, Neoplastic Diethylnitrosamine 6.6121159647 7505956 2727394 17174075
MESH:D002547 Cerebral Palsy Toluene 5.879294310
MESH:D018281 Cholangiocarcinoma Diethylnitrosamine 9.3319052882
MESH:D018281 Cholangiocarcinoma Tetrachlorodibenzodioxin 9.3316835633
MESH:D002764 Cholecystitis Indomethacin 5.2011181007
MESH:D002779 Cholestasis Cyclosporine 7.7819486331
MESH:D002779 Cholestasis Ethinyl Estradiol 7.7817333356 16919318 15861022 11677210 17681005 16105132 17110522
MESH:D002972 Cleft Palate Tetrachlorodibenzodioxin 2.1015668235 12621046 15340226 16354765 8697196
MESH:D003092 Colitis Selenium 3.7917936198
MESH:D003110 Colonic Neoplasms Indomethacin 4.1011260862 15963497 15637740 15786552 15936596 15625704
MESH:D003110 Colonic Neoplasms irinotecan 4.1017287894 17725105
MESH:D015179 Colorectal Neoplasms Indomethacin 2.8612606626 18059344 11197048 17054584
MESH:D015179 Colorectal Neoplasms irinotecan 2.8615273666 18509181 17454858 16303861 17159606 16391804 18259882
MESH:D000013 Congenital Abnormalities Tetrachlorodibenzodioxin 3.0614669216 17141729
MESH:D018352 Coronavirus Infections Indomethacin 5.7517302372
MESH:D019465 Craniofacial Abnormalities Benzene 3.9815643154
MESH:D019465 Craniofacial Abnormalities Tetrachlorodibenzodioxin 3.9810048152 15322242 20055451
MESH:D019465 Craniofacial Abnormalities Toluene 3.989294310
MESH:D003643 Death Toluene 5.706431079
MESH:D003872 Dermatitis Benzene 4.7815902427
MESH:D003924 Diabetes Mellitus, Type 2 Diethylnitrosamine 4.2220387270
MESH:D003924 Diabetes Mellitus, Type 2 Tetrachlorodibenzodioxin 4.2217107852
MESH:D003967 Diarrhea Indomethacin 3.807907874 7237001
MESH:D056486 Drug-Induced Liver Injury Amiodarone 12.0615265979 18218290
MESH:D056486 Drug-Induced Liver Injury Diethylnitrosamine 12.0619107877
MESH:D056486 Drug-Induced Liver Injury Selenium 12.0615131321
MESH:D056486 Drug-Induced Liver Injury Tetrachlorodibenzodioxin 12.0620420201
MESH:D056486 Drug-Induced Liver Injury Trichloroethylene 12.067120509
MESH:D004362 Drug Toxicity Tetrachlorodibenzodioxin 2.7611462148
MESH:D004374 Ductus Arteriosus, Patent Indomethacin 5.1717190690 18446180 16326151 16133044 12774134 18043480
MESH:D004381 Duodenal Ulcer Indomethacin 4.1411535926 17351913 17151854 17045617 17329845 11595431 11595415 11991626 16699067 10671773 17202747
MESH:D004487 Edema Indomethacin 6.937907874 8985016 19703484 7990266 16100529 8273558 10653021
MESH:D004487 Edema Tetrachlorodibenzodioxin 6.9311000095 12711302
MESH:D004489 Edema, Cardiac Tetrachlorodibenzodioxin 3.9315322242 16714409 18230668
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Ethinyl Estradiol 3.2012538720
MESH:D004715 Endometriosis Indomethacin 9.0815652904
MESH:D004715 Endometriosis Tetrachlorodibenzodioxin 9.0810568697 9294722
MESH:D019446 Endotoxemia Indomethacin 4.5218509659
MESH:D004751 Enteritis Indomethacin 4.7817763956 10567023 16328016
MESH:D020345 Enterocolitis, Necrotizing Indomethacin 5.0017980183
MESH:D004802 Eosinophilia Indomethacin 4.0711298111
MESH:D004931 Esophageal Achalasia Diethylnitrosamine 5.1516302075
MESH:D004938 Esophageal Neoplasms Indomethacin 2.8111005569
MESH:D005124 Eye Abnormalities Tetrachlorodibenzodioxin 3.0111564622
MESH:D005234 Fatty Liver Amiodarone 18.8214986274
MESH:D005234 Fatty Liver Cyclosporine 18.8219224547
MESH:D005234 Fatty Liver Diethylnitrosamine 18.8220387270 21071580
MESH:D005234 Fatty Liver Ethinyl Estradiol 18.8215345470
MESH:D005313 Fetal Death Tetrachlorodibenzodioxin 3.4711858732
MESH:D005334 Fever Indomethacin 4.1217627676 10431976 11852909
MESH:D005354 Fibrosarcoma Indomethacin 4.9110962813
MESH:D005355 Fibrosis Cyclosporine 14.8812639820 12168785
MESH:D005355 Fibrosis Indomethacin 14.8817994277
MESH:D005355 Fibrosis Tetrachlorodibenzodioxin 14.8820067830
MESH:D005499 Folliculitis Indomethacin 5.2011298111
MESH:D005756 Gastritis Indomethacin 4.7815046732
MESH:D005885 Gingival Hyperplasia Cyclosporine 4.248708960
MESH:D005909 Glioblastoma Indomethacin 3.5612870263
MESH:D005910 Glioma Indomethacin 3.2318371953 16487511
MESH:D005923 Glomerulosclerosis, Focal Segmental Indomethacin 4.2911849393
MESH:D006058 Gonadal Disorders Tetrachlorodibenzodioxin 4.6210696789
MESH:D006073 Gout Indomethacin 5.3711248219
MESH:D006258 Head and Neck Neoplasms Indomethacin 3.7415482327
MESH:D006330 Heart Defects, Congenital Tetrachlorodibenzodioxin 2.3310048152 11294989
MESH:D006333 Heart Failure Selenium 3.0717162251
MESH:D006402 Hematologic Diseases Benzene 4.6616183116
MESH:D006457 Hemoglobinuria, Paroxysmal Cyclosporine 4.4415720958
MESH:D006470 Hemorrhage Tetrachlorodibenzodioxin 3.3411000095
MESH:D006501 Hepatic Encephalopathy Indomethacin 4.5715633222
MESH:D019698 Hepatitis C, Chronic Indomethacin 4.6915135802
MESH:D006529 Hepatomegaly 2-xylene 14.787457013 7457028
MESH:D006529 Hepatomegaly Amiodarone 14.7815265979
MESH:D006529 Hepatomegaly Tetrachlorodibenzodioxin 14.7815340226 12621046 16120746
MESH:D006869 Hydronephrosis Tetrachlorodibenzodioxin 4.0816354765 15340226 16959395 18606429 8697196
MESH:D006930 Hyperalgesia Indomethacin 3.7712727271
MESH:D034321 Hyperamylasemia Indomethacin 5.7517883296
MESH:D006937 Hypercholesterolemia Amiodarone 3.889751232 8137927
MESH:D006940 Hyperemia Indomethacin 5.0212524144
MESH:D006949 Hyperlipidemias Indomethacin 4.1717546600
MESH:D006973 Hypertension Benzene 8.6217940673
MESH:D006973 Hypertension Cyclosporine 8.6210903974
MESH:D006973 Hypertension Tetrachlorodibenzodioxin 8.6218850075 18670907
MESH:D007021 Hypospadias Ethinyl Estradiol 3.8216945680 16569931
MESH:D007037 Hypothyroidism Amiodarone 4.5318020914 17991464
MESH:D007077 Ileal Diseases Indomethacin 5.0618306037 10574470
MESH:D007079 Ileitis Indomethacin 5.3716133968 10651667 10647630
MESH:D007235 Infant, Premature, Diseases Indomethacin 5.4016133044
MESH:D007247 Infertility, Female Ethinyl Estradiol 3.4712013081
MESH:D007248 Infertility, Male Ethinyl Estradiol 2.4917937319
MESH:D007249 Inflammation Diethylnitrosamine 8.3618785209
MESH:D007249 Inflammation Indomethacin 8.3612568917 7812673 3291741
MESH:D007249 Inflammation Tetrachlorodibenzodioxin 8.3612200463 12878042
MESH:D007251 Influenza, Human Selenium 4.2316624496
MESH:D007410 Intestinal Diseases Indomethacin 4.3417994277 10210152 11686837 18236018 15831440 15610444 17329856 11855677 11713966
MESH:D019586 Intracranial Hypertension Indomethacin 5.4015241188
MESH:D007569 Jaw Abnormalities Tetrachlorodibenzodioxin 3.3416580747
MESH:D007579 Jejunal Diseases Indomethacin 5.0618306037 16133968 10574470
MESH:D007638 Keratoconjunctivitis Sicca Cyclosporine 4.4715604871
MESH:D007674 Kidney Diseases Cyclosporine 6.198314463 10903974 18776723
MESH:D007674 Kidney Diseases Indomethacin 6.1917190690
MESH:D007676 Kidney Failure, Chronic Selenium 3.8916518626
MESH:D007680 Kidney Neoplasms Cyclosporine 2.7412371664
MESH:D016773 Leishmaniasis, Cutaneous Indomethacin 3.9010320625 12228301 11703811
MESH:D007938 Leukemia Benzene 3.3915935818 17119257 14694614 18335105
MESH:D015464 Leukemia, Myelogenous, Chronic, BCR-ABL Positive Indomethacin 3.9316572323 10785260 15631656
MESH:D007951 Leukemia, Myeloid Benzene 4.3217506065
MESH:D015470 Leukemia, Myeloid, Acute Benzene 4.2919478238
MESH:D015470 Leukemia, Myeloid, Acute Indomethacin 4.2918360721
MESH:D007964 Leukocytosis Indomethacin 5.4016537180
MESH:D007969 Leukomalacia, Periventricular Indomethacin 5.7517980183
MESH:D008064 Lipidoses Amiodarone 3.5117567588 15342952
MESH:D008101 Liver Abscess, Amebic Indomethacin 5.7511479899
MESH:D008103 Liver Cirrhosis Diethylnitrosamine 2.8220032147 18407596 18665156 18522880 19638242
MESH:D008106 Liver Cirrhosis, Experimental Indomethacin 2.5118194892
MESH:D008106 Liver Cirrhosis, Experimental Tetrachlorodibenzodioxin 2.5112878042
MESH:D008107 Liver Diseases Diethylnitrosamine 2.1017034775
MESH:D008113 Liver Neoplasms beta-Naphthoflavone 7.4619389873 21295105
MESH:D008113 Liver Neoplasms Diethylnitrosamine 7.4615175105 2862719 19294768 15885732 18648771 19638242 19255062 19833225 20434301 21278145 19254457 19690152 20101389 20452335 19996281 19427195 21167192 20405173 20583210 19551842 19850985 12112319 18977376 18978307 19426721 20501860 21047994 19499222 9163691 10737359 19642983 16942905 18754104 20492335 19090486 18644402 12771043 19812893 2422723 20118626 20137499 21071580 19073162 19256749
MESH:D008113 Liver Neoplasms Tetrachlorodibenzodioxin 7.4616984957
MESH:D008114 Liver Neoplasms, Experimental Benzene 18.7112562636
MESH:D008114 Liver Neoplasms, Experimental beta-Naphthoflavone 18.7118164116
MESH:D008114 Liver Neoplasms, Experimental Diethylnitrosamine 18.7116842330 19519916 17854601 17942915 18282651 21159647 18308698 9362446 19539802 18253720 18164116 18775883 19009564 19126423 3124819 18079962 16267830 18093689 2563599 17174075 18544905 19004024
MESH:D008114 Liver Neoplasms, Experimental Tetrachlorodibenzodioxin 18.7112151625
MESH:D008114 Liver Neoplasms, Experimental Trichloroethylene 18.717955063
MESH:D008133 Long QT Syndrome Amiodarone 3.5817391786 11989578 15350150
MESH:D008171 Lung Diseases Amiodarone 3.3712587719
MESH:D017563 Lung Diseases, Interstitial Amiodarone 11.5718516814
MESH:D017563 Lung Diseases, Interstitial Benzene 11.5714698565
MESH:D008175 Lung Neoplasms Benzene 6.6412562636
MESH:D008175 Lung Neoplasms Diethylnitrosamine 6.6421163286 20512841 6695378 20970405
MESH:D008175 Lung Neoplasms Indomethacin 6.6411497255 16537180 11053908
MESH:D008175 Lung Neoplasms Methylene Chloride 6.6415172992
MESH:D008175 Lung Neoplasms Tetrachlorodibenzodioxin 6.6419555203 11884234
MESH:D008223 Lymphoma Benzene 3.7417584886 17119257
MESH:D015674 Mammary Neoplasms, Animal Benzene 4.4612562636
MESH:D008325 Mammary Neoplasms, Experimental Benzene 6.3011921183
MESH:D008325 Mammary Neoplasms, Experimental Selenium 6.3015318939
MESH:D008607 Mental Retardation Toluene 3.659294310
MESH:D008654 Mesothelioma Selenium 2.7915107826
MESH:D008664 Metal Metabolism, Inborn Errors Cyclosporine 4.8216801185
MESH:D008881 Migraine Disorders Indomethacin 3.6711903285
MESH:D019957 Motor Skills Disorders Toluene 5.249294310
MESH:D009062 Mouth Neoplasms Indomethacin 3.9912636206
MESH:D052016 Mucositis irinotecan 5.0317159606
MESH:D009101 Multiple Myeloma Benzene 3.6617119195
MESH:D009181 Mycoses Amiodarone 4.9317974566 12754197
MESH:D017202 Myocardial Ischemia Tetrachlorodibenzodioxin 3.0212213967
MESH:D009362 Neoplasm Metastasis Diethylnitrosamine 9.659029167 3581430
MESH:D009362 Neoplasm Metastasis Indomethacin 9.6511053908 16537180 11239499
MESH:D009362 Neoplasm Metastasis irinotecan 9.6518259882
MESH:D009369 Neoplasms Trichloroethylene 3.5511911487
MESH:D009374 Neoplasms, Experimental Indomethacin 4.1510663608 15625704
MESH:D009402 Nephrosis, Lipoid Cyclosporine 4.4717954296
MESH:D009404 Nephrotic Syndrome Cyclosporine 3.2919348381 18481113
MESH:D009421 Nervous System Malformations Tetrachlorodibenzodioxin 3.2214600291
MESH:D009436 Neural Tube Defects Benzene 3.6715643154
MESH:D009447 Neuroblastoma irinotecan 3.488761367
MESH:D019636 Neurodegenerative Diseases Diethylnitrosamine 8.5820387270
MESH:D019636 Neurodegenerative Diseases Indomethacin 8.5812349958
MESH:D017599 Neuroectodermal Tumors irinotecan 4.758761367
MESH:D009461 Neurologic Manifestations Diethylnitrosamine 5.1520387270
MESH:D007752 Obstetric Labor, Premature Indomethacin 5.206374098
MESH:D009784 Occupational Diseases Benzene 4.1815727169 17178637 17119257 15913788 15612468 17479406 15576619 16737584 15935809
MESH:D010003 Osteoarthritis Indomethacin 3.677009135
MESH:D010051 Ovarian Neoplasms Benzene 2.9712562636
MESH:D010146 Pain Indomethacin 3.4613679232 3291741 17440234 17627676
MESH:D010149 Pain, Postoperative Indomethacin 4.7112538197 18702446
MESH:D010190 Pancreatic Neoplasms Diethylnitrosamine 2.4216540662
MESH:D010195 Pancreatitis Indomethacin 3.9315028970 17883296
MESH:D016584 Panic Disorder Ethinyl Estradiol 3.6911578682
MESH:D010257 Paraneoplastic Syndromes Indomethacin 5.7516537180
MESH:D020734 Parkinsonian Disorders Indomethacin 4.1212349958
MESH:D051302 Paroxysmal Hemicrania Indomethacin 5.7511903285
MESH:D010382 Peliosis Hepatis Tetrachlorodibenzodioxin 4.2812520081
MESH:D010437 Peptic Ulcer Indomethacin 5.1711148446
MESH:D010518 Periodontitis Indomethacin 4.9417225004
MESH:D010954 Plasmacytoma Selenium 4.9215087411
MESH:D017119 Porphyria Cutanea Tarda Tetrachlorodibenzodioxin 3.5718163543
MESH:D011230 Precancerous Conditions Cyclosporine 8.9512371664
MESH:D011230 Precancerous Conditions Diethylnitrosamine 8.952563599
MESH:D047928 Premature Birth Indomethacin 5.1417000239
MESH:D011297 Prenatal Exposure Delayed Effects Tetrachlorodibenzodioxin 3.2111222880 11118676 11399792 11896295
MESH:D011507 Proteinuria Indomethacin 4.1711849393
MESH:D011537 Pruritus Ethinyl Estradiol 3.3315861022 16919318
MESH:D011565 Psoriasis Cyclosporine 2.2316882103
MESH:D011658 Pulmonary Fibrosis Amiodarone 2.8511597910 12832656 12490602
MESH:D015619 Respiratory System Abnormalities Tetrachlorodibenzodioxin 3.8518990726
MESH:D012640 Seizures Toluene 3.729294310 6431079
OMIM:609620 SHORT QT SYNDROME 1 Amiodarone 5.1018724381
MESH:D012878 Skin Neoplasms Tetrachlorodibenzodioxin 2.0416192470
MESH:D013088 Spermatocele Ethinyl Estradiol 3.9716709447
MESH:D013272 Stomach Diseases Indomethacin 4.4410192188 15472012 18209964 15038085 16280098 10486359 17638125 16184426 17160473 18545984 17207306 10215738 16113693
MESH:D013274 Stomach Neoplasms Benzene 4.8012562636
MESH:D013274 Stomach Neoplasms Diethylnitrosamine 4.8018456281
MESH:D013274 Stomach Neoplasms Indomethacin 4.8015609394
MESH:D013274 Stomach Neoplasms irinotecan 4.8015723263
MESH:D013276 Stomach Ulcer Amiodarone 7.5218087811
MESH:D013276 Stomach Ulcer Indomethacin 7.5214567935 17977527 11729361 10878458 18237397 18193104 17135157 17895592 15255614 16934674 18726076 16631530 17627676 17918041 18299717 10423059 17654042 17657623 15104355 1323529 12787963 11906479 18087811 16169175 15138204 16252198 12077510 16755016 11595431 16150113 18209962 18431645 11145282 10750652 18543354 12498302 16397915 12500499 18181030 12467913 11523592 11595415
MESH:D013610 Tachycardia Amiodarone 4.3011238279
MESH:D017180 Tachycardia, Ventricular Amiodarone 4.2019225199
MESH:D013733 Testicular Diseases Toluene 4.9810048760 10514026
MESH:D019851 Thrombophilia Ethinyl Estradiol 3.6311994571
MESH:D013927 Thrombosis Ethinyl Estradiol 3.1515669648
MESH:D013953 Thymus Neoplasms Benzene 4.9810850423
MESH:D013959 Thyroid Diseases Amiodarone 12.1519731979
MESH:D013959 Thyroid Diseases Tetrachlorodibenzodioxin 12.1512697716
MESH:D013964 Thyroid Neoplasms Diethylnitrosamine 7.387505956
MESH:D013964 Thyroid Neoplasms Indomethacin 7.3814736730 18791128 11352223
MESH:D013971 Thyrotoxicosis Amiodarone 4.8719584973 18020914
MESH:D016171 Torsades de Pointes Amiodarone 4.2117467628 11989578
MESH:D014456 Ulcer Indomethacin 4.9110574470 17380554
MESH:D014594 Uterine Neoplasms Benzene 9.6012562636
MESH:D014594 Uterine Neoplasms Ethinyl Estradiol 9.6014692618
MESH:D014605 Uveitis Cyclosporine 4.011336536
MESH:D054079 Vascular Malformations Tetrachlorodibenzodioxin 4.6212125929
MESH:D020246 Venous Thrombosis Ethinyl Estradiol 3.5414671159 15869587
MESH:D014839 Vomiting Indomethacin 4.7811897121
MESH:D019282 Wasting Syndrome Tetrachlorodibenzodioxin 4.2815886252
MESH:D014985 Xerophthalmia Cyclosporine 4.4717120751
No data
Pharmacogenomics Knowledge Base Top
Drug Bank Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018