AutismKB 2.0

Annotation Detail for DPYSL5


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Basic Information Top
Gene Symbol:DPYSL5 ( CRAM,CRMP-5,CRMP5,FLJ45383,Ulip6 )
Gene Full Name: dihydropyrimidinase-like 5
Band: 2p23.3
Quick LinksEntrez ID:56896; OMIM: 608383; Uniprot ID:DPYL5_HUMAN; ENSEMBL ID: ENSG00000157851; HGNC ID: 20637
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
No data
Pathway IDPathway Name
hsa04360Axon guidance
Pathway IDPathway Name
Axon guidance
No data
Pathway IDPathway Name
P00007Axon guidance mediated by semaphorins
P02771Pyrimidine Metabolism
No data
Related Diseases/Disorders Top
No data
Desease IDDesease Name
1791Neuropathy
1808Eye disease
2066Lung cancer
2188Bone marrow disease
No data
No data
No data
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C548651 2-(1'H-indolo-3'-carbonyl)thiazole-4-carboxylic acid methyl ester 2-(1'H-indolo-3'-carbonyl)thiazole-4-carboxylic acid methyl ester results in decreased expression of DPYSL5 mRNAdecreases expression 19933214
D000643 Ammonium Chloride Ammonium Chloride affects the expression of DPYSL5 mRNAaffects expression 16483693
D005419 Flavonoids Flavonoids results in decreased expression of DPYSL5 mRNAdecreases expression 18035473
D014501 Uranium Uranium results in increased expression of DPYSL5 mRNAincreases expression 15672453
C005460 uranyl acetate uranyl acetate results in increased expression of DPYSL5 mRNAincreases expression 15672453
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000138 Acidosis Ammonium Chloride 4.1018287403
MESH:D007249 Inflammation Flavonoids 2.8017296493
Pathway ID Pathway Name
REACT:18266 Axon guidance
KEGG:04360 Axon guidance
Pharmacogenomics Knowledge Base Top
Drug Bank Top

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Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018