Annotation Detail for SMYD2
Basic Information Top
| Gene Symbol: | SMYD2 ( HSKM-B,KMT3C,MGC119305,ZMYND14 ) |
|---|---|
| Gene Full Name: | SET and MYND domain containing 2 |
| Band: | 1q32.3 |
| Quick Links | Entrez ID:56950; OMIM: 610663; Uniprot ID:SMYD2_HUMAN; ENSEMBL ID: ENSG00000143499; HGNC ID: 20982 |
| Relate to Another Database: | SFARIGene; denovo-db |
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| Pathway ID | Pathway Name |
|---|---|
| 200175 | p53 pathway |
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| Chemical ID | Chemical Name | Interaction | Interaction Action | Publication |
|---|---|---|---|---|
| D000082 | Acetaminophen | Acetaminophen affects the expression of SMYD2 mRNA | affects expression | 17562736 |
| D014810 | Vitamin E | Vitamin E results in decreased expression of SMYD2 mRNA | decreases expression | 19244175 |
| Disease ID | Disease Name | Direct Evidence | Inference Chemical Name | Inference Score | Publication |
|---|---|---|---|---|---|
| MESH:D000799 | Angioedema | Acetaminophen | 4.91 | 10982225 | |
| MESH:D001321 | Autistic Disorder | Acetaminophen | 1.39 | 18445737 | |
| MESH:D002252 | Carbon Tetrachloride Poisoning | Vitamin E | 4.69 | 16050911 | |
| MESH:D006528 | Carcinoma, Hepatocellular | Acetaminophen | 1.41 | 3084413 | |
| MESH:D002386 | Cataract | Acetaminophen | 2.83 | 10977129 | |
| MESH:D019465 | Craniofacial Abnormalities | Vitamin E | 1.93 | 19769572 | |
| MESH:D056486 | Drug-Induced Liver Injury | Acetaminophen | 1.68 | 14986274 11739529 19164858 16081117 16177239 11287661 16393943 19739265 19923254 18071297 2444490 10915739 19420014 16109766 16227642 19416960 12594235 18713872 19370779 12705907 10774834 11461765 15619225 11421492 12153990 16781746 14550746 14725611 17562736 17906064 12540782 11743745 19085960 17522070 11834606 11529661 16485898 15968718 12392966 10663392 12958197 | |
| MESH:D056487 | Drug-Induced Liver Injury, Chronic | Acetaminophen | 5.17 | 19426721 | |
| MESH:C538011 | Eales disease | Vitamin E | 5.77 | 9068938 | |
| MESH:D005756 | Gastritis | Acetaminophen | 4.74 | 16983495 | |
| MESH:D006330 | Heart Defects, Congenital | Vitamin E | 3.20 | 16080930 | |
| MESH:D006548 | Hernia, Diaphragmatic | Vitamin E | 2.83 | 16490937 16863852 | |
| MESH:D019584 | Hot Flashes | Vitamin E | 5.04 | 14716179 | |
| MESH:D006930 | Hyperalgesia | Acetaminophen | 3.11 | 16870215 | |
| MESH:D007251 | Influenza, Human | Vitamin E | 5.28 | 16624496 | |
| MESH:D007674 | Kidney Diseases | Acetaminophen | 6.80 | 15629191 12587719 | |
| MESH:D007674 | Kidney Diseases | Vitamin E | 6.80 | 12488133 | |
| MESH:D008106 | Liver Cirrhosis, Experimental | Vitamin E | 1.91 | 16169303 | |
| MESH:D008107 | Liver Diseases | Acetaminophen | 1.71 | 19460945 16611625 19014921 12969438 12587719 19784758 11587558 16610002 | |
| MESH:D017114 | Liver Failure, Acute | Acetaminophen | 3.74 | 16871587 17185352 | |
| MESH:D008171 | Lung Diseases | Vitamin E | 3.48 | 16863852 | |
| MESH:D008175 | Lung Neoplasms | Vitamin E | 1.90 | 11062179 | |
| MESH:D008546 | Melanoma, Experimental | Acetaminophen | 4.33 | 19513568 | |
| MESH:D019636 | Neurodegenerative Diseases | Acetaminophen | 3.31 | 18514411 | |
| MESH:D010146 | Pain | Acetaminophen | 2.82 | 16870215 | |
| MESH:D011471 | Prostatic Neoplasms | Vitamin E | 3.23 | 15084515 | |
| MESH:D012871 | Skin Diseases | Vitamin E | 2.53 | 18709164 | |
| MESH:D020521 | Stroke | Vitamin E | 3.93 | 16517955 | |
| MESH:D014581 | Urticaria | Acetaminophen | 3.58 | 10982225 |
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