AutismKB 2.0

Annotation Detail for PARP6


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Basic Information Top
Gene Symbol:PARP6 ( MGC131971,pART17 )
Gene Full Name: poly (ADP-ribose) polymerase family, member 6
Band: 15q23
Quick LinksEntrez ID:56965; OMIM: NA; Uniprot ID:PARP6_HUMAN; ENSEMBL ID: ENSG00000137817; HGNC ID: 26921
Relate to Another Database: SFARIGene; denovo-db
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Chemical ID Chemical Name Interaction Interaction Action Publication
C006253 pirinixic acid pirinixic acid results in increased expression of PARP6 mRNAincreases expression 18301758
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D055371 Acute Lung Injury pirinixic acid 3.8118653653
MESH:D018248 Adenoma, Liver Cell pirinixic acid 4.5716434500
MESH:D001778 Blood Coagulation Disorders pirinixic acid 3.7719483382
MESH:D002779 Cholestasis pirinixic acid 3.2319176532
MESH:D003876 Dermatitis, Atopic pirinixic acid 2.6218249437
MESH:D004487 Edema pirinixic acid 3.1012083418
MESH:D005234 Fatty Liver pirinixic acid 3.3919236843 20131406
MESH:D006333 Heart Failure pirinixic acid 2.8320558911
MESH:D006529 Hepatomegaly pirinixic acid 3.9019176532 19772884 16221962 18467677
MESH:D006943 Hyperglycemia pirinixic acid 3.7620558911
MESH:D007333 Insulin Resistance pirinixic acid 2.9616306350
MESH:D008106 Liver Cirrhosis, Experimental pirinixic acid 1.3515474484
MESH:D008113 Liver Neoplasms pirinixic acid 1.9720007298 16377806 15890375
MESH:D009135 Muscular Diseases pirinixic acid 4.4116239165
MESH:D009203 Myocardial Infarction pirinixic acid 2.3119151258
MESH:D015428 Myocardial Reperfusion Injury pirinixic acid 3.3716411023
MESH:D009369 Neoplasms pirinixic acid 2.1617405874
MESH:D009765 Obesity pirinixic acid 1.9020558911
MESH:D015427 Reperfusion Injury pirinixic acid 2.6019058328
No data
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  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018