Gene Symbol:	TOMM22 ( 1C9-2,MST065,MSTP065,TOM22 )
Gene Full Name:	translocase of outer mitochondrial membrane 22 homolog (yeast)
Band:	22q13.1
Quick Links	Entrez ID:56993; OMIM: 607046; Uniprot ID:TOM22_HUMAN; ENSEMBL ID: ENSG00000100216; HGNC ID: 18002
Relate to Another Database:	SFARIGene; denovo-db

Chemical ID	Chemical Name	Interaction	Interaction Action	Publication
C023514	2,6-dinitrotoluene	2,6-dinitrotoluene affects the expression of TOMM22 mRNA	affects expression	21346803
D001564	Benzo(a)pyrene	Benzo(a)pyrene results in decreased expression of TOMM22 mRNA	decreases expression	20106945
D002995	Clofibric Acid	[Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of TOMM22 mRNA	affects cotreatment\|affects expression	17602206
D004052	Diethylnitrosamine	[Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of TOMM22 mRNA	affects cotreatment\|affects expression	17602206

Disease ID	Disease Name	Inference Chemical Name	Inference Score	Publication
MESH:D000230	Adenocarcinoma	Benzo(a)pyrene	2.06	20127859 20464547
MESH:D000236	Adenoma	Benzo(a)pyrene	7.32	6695378
MESH:D000236	Adenoma	Diethylnitrosamine	7.32	10737359 6695378
MESH:D018248	Adenoma, Liver Cell	Diethylnitrosamine	4.53	17620307 18056438 17162532 19061943 16434500 19052882
MESH:D017544	Aortic Aneurysm, Abdominal	Benzo(a)pyrene	4.64	19183758
MESH:D001943	Breast Neoplasms	Benzo(a)pyrene	2.05	20146248 17474063
MESH:D001943	Breast Neoplasms	Diethylnitrosamine	2.05	17474063
MESH:D006528	Carcinoma, Hepatocellular	2,6-dinitrotoluene	3.13	16705839
MESH:D006528	Carcinoma, Hepatocellular	Diethylnitrosamine	3.13	17978847 16830150 19701751 20514400 16288022 11831363 18506893 16807293 19171122 19208518 16779866 20727157 19539802 18665156 18393292 10672840 18210153 20084675 17761372 20432363 17173139 20524982 16569478 18788625 3084413 16878318 21159647 19519916 20007298 16681979 17138121 19418558 19052882 17162532 19822196 19383236 3581430 19394651 19335982 20101231 16935385 16502159 18978308 17428255 20512989 10737359 18494052 20214788 20935162 16698587 18971187 19107877 16540662 17055752 16328049 18056438 18785209 19919837 18691550
MESH:D002294	Carcinoma, Squamous Cell	Benzo(a)pyrene	2.13	20419170
MESH:D002471	Cell Transformation, Neoplastic	2,6-dinitrotoluene	7.58	6135515
MESH:D002471	Cell Transformation, Neoplastic	Diethylnitrosamine	7.58	7505956 2727394 17174075 21159647
MESH:D018281	Cholangiocarcinoma	Diethylnitrosamine	4.05	19052882
MESH:D003490	Cyanosis	2,6-dinitrotoluene	4.58	18551238
MESH:D003924	Diabetes Mellitus, Type 2	Diethylnitrosamine	2.26	20387270
MESH:D056486	Drug-Induced Liver Injury	2,6-dinitrotoluene	4.20	21346803 18551238
MESH:D056486	Drug-Induced Liver Injury	Diethylnitrosamine	4.20	19107877
MESH:D004931	Esophageal Achalasia	Diethylnitrosamine	5.84	16302075
MESH:D004938	Esophageal Neoplasms	Benzo(a)pyrene	2.08	16530937
MESH:D005234	Fatty Liver	Diethylnitrosamine	3.61	21071580 20387270
MESH:D006330	Heart Defects, Congenital	Benzo(a)pyrene	2.83	20471113
MESH:D007249	Inflammation	Diethylnitrosamine	2.55	18785209
MESH:D007680	Kidney Neoplasms	2,6-dinitrotoluene	3.32	16705839
MESH:D008103	Liver Cirrhosis	Diethylnitrosamine	3.01	18522880 20032147 18407596 18665156 19638242
MESH:D008107	Liver Diseases	Diethylnitrosamine	2.17	17034775
MESH:D008113	Liver Neoplasms	2,6-dinitrotoluene	11.76	7678174
MESH:D008113	Liver Neoplasms	Benzo(a)pyrene	11.76	21137059 20195826
MESH:D008113	Liver Neoplasms	Clofibric Acid	11.76	17602206
MESH:D008113	Liver Neoplasms	Diethylnitrosamine	11.76	18978307 19073162 19255062 19426721 19642983 19833225 21071580 21047994 19294768 19812893 2862719 18644402 21167192 16942905 18648771 12771043 18977376 20452335 19551842 21278145 10737359 19499222 2422723 20137499 15175105 19427195 20118626 18754104 20405173 19638242 19254457 19690152 20501860 12112319 20583210 20434301 9163691 19090486 20492335 15885732 19256749 19850985 20101389 19996281
MESH:D008114	Liver Neoplasms, Experimental	2,6-dinitrotoluene	6.69	6135515 2876786 2876784
MESH:D008114	Liver Neoplasms, Experimental	Diethylnitrosamine	6.69	18093689 17174075 18775883 18308698 18079962 19539802 19126423 9362446 18544905 16267830 18164116 21159647 19009564 17854601 18253720 17942915 16842330 18282651 19519916 2563599 3124819 19004024
MESH:D008175	Lung Neoplasms	Benzo(a)pyrene	2.46	17053015 20869020 20464547 20064080 18520028 18569708 6695378 18816296 20135361
MESH:D008175	Lung Neoplasms	Diethylnitrosamine	2.46	20512841 20970405 6695378 21163286
MESH:D009062	Mouth Neoplasms	Benzo(a)pyrene	3.50	16381670
MESH:D009336	Necrosis	2,6-dinitrotoluene	4.49	7678174 18551238
MESH:D009362	Neoplasm Metastasis	Diethylnitrosamine	2.69	3581430 9029167
MESH:D009369	Neoplasms	Benzo(a)pyrene	2.33	11141357
MESH:D019636	Neurodegenerative Diseases	Diethylnitrosamine	3.69	20387270
MESH:D009461	Neurologic Manifestations	Diethylnitrosamine	5.84	20387270
MESH:D009784	Occupational Diseases	2,6-dinitrotoluene	3.83	16049721
MESH:D010190	Pancreatic Neoplasms	Diethylnitrosamine	2.53	16540662
MESH:D011230	Precancerous Conditions	Diethylnitrosamine	3.92	2563599
MESH:D011471	Prostatic Neoplasms	Benzo(a)pyrene	2.91	17292933
MESH:D012640	Seizures	2,6-dinitrotoluene	2.79	18551238
MESH:D012878	Skin Neoplasms	Benzo(a)pyrene	2.52	19755658 10029692
MESH:D013274	Stomach Neoplasms	Benzo(a)pyrene	2.40	20155912 2093021
MESH:D013274	Stomach Neoplasms	Diethylnitrosamine	2.40	18456281
MESH:D013964	Thyroid Neoplasms	Diethylnitrosamine	3.29	7505956
MESH:D001749	Urinary Bladder Neoplasms	2,6-dinitrotoluene	5.39	16049721
MESH:D001749	Urinary Bladder Neoplasms	Benzo(a)pyrene	5.39	17053015
MESH:D014571	Urologic Neoplasms	2,6-dinitrotoluene	4.95	10091137

AutismKB 2.0

Annotation Detail for TOMM22

Simple Query:

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics