AutismKB 2.0

Annotation Detail for SLC12A9


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Basic Information Top
Gene Symbol:SLC12A9 ( CIP1,FLJ46905 )
Gene Full Name: solute carrier family 12 (potassium/chloride transporters), member 9
Band: 7q22.1
Quick LinksEntrez ID:56996; OMIM: NA; Uniprot ID:S12A9_HUMAN; ENSEMBL ID: ENSG00000146828; HGNC ID: 17435
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
Related Diseases/Disorders Top
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C016403 2,4-dinitrotoluene 2,4-dinitrotoluene affects the expression of SLC12A9 mRNAaffects expression 21346803
C023514 2,6-dinitrotoluene 2,6-dinitrotoluene affects the expression of SLC12A9 mRNAaffects expression 21346803
D000082 Acetaminophen Acetaminophen affects the expression of SLC12A9 mRNAaffects expression 17562736
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000799 Angioedema Acetaminophen 4.7110982225
MESH:D001321 Autistic Disorder Acetaminophen 1.3918445737
MESH:D006528 Carcinoma, Hepatocellular 2,4-dinitrotoluene 4.8016705839
MESH:D006528 Carcinoma, Hepatocellular 2,6-dinitrotoluene 4.8016705839
MESH:D006528 Carcinoma, Hepatocellular Acetaminophen 4.803084413
MESH:D002386 Cataract Acetaminophen 2.8110977129
MESH:D002471 Cell Transformation, Neoplastic 2,6-dinitrotoluene 3.066135515
MESH:D003490 Cyanosis 2,4-dinitrotoluene 13.1618551238
MESH:D003490 Cyanosis 2,6-dinitrotoluene 13.1618551238
MESH:D056486 Drug-Induced Liver Injury 2,4-dinitrotoluene 6.7818551238 21346803
MESH:D056486 Drug-Induced Liver Injury 2,6-dinitrotoluene 6.7818551238 21346803
MESH:D056486 Drug-Induced Liver Injury Acetaminophen 6.7816485898 2444490 10663392 19085960 14550746 15968718 19370779 12594235 11461765 17906064 18713872 16227642 19416960 16177239 19739265 14986274 11529661 12958197 14725611 11421492 17562736 19164858 11739529 19420014 12540782 19923254 16781746 18071297 10774834 10915739 16393943 12705907 11743745 16109766 12153990 11287661 12392966 15619225 16081117 17522070 11834606
MESH:D056487 Drug-Induced Liver Injury, Chronic Acetaminophen 4.9619426721
MESH:D005756 Gastritis Acetaminophen 4.5416983495
MESH:D006930 Hyperalgesia Acetaminophen 3.0616870215
MESH:D007674 Kidney Diseases Acetaminophen 2.4215629191 12587719
MESH:D007680 Kidney Neoplasms 2,4-dinitrotoluene 8.6716705839
MESH:D007680 Kidney Neoplasms 2,6-dinitrotoluene 8.6716705839
MESH:D008107 Liver Diseases Acetaminophen 1.7119784758 16610002 16611625 19460945 12969438 11587558 12587719 19014921
MESH:D017114 Liver Failure, Acute Acetaminophen 3.6817185352 16871587
MESH:D008113 Liver Neoplasms 2,6-dinitrotoluene 2.287678174
MESH:D008114 Liver Neoplasms, Experimental 2,6-dinitrotoluene 2.792876786 2876784 6135515
MESH:D008546 Melanoma, Experimental Acetaminophen 4.2219513568
MESH:D009336 Necrosis 2,4-dinitrotoluene 12.9618551238
MESH:D009336 Necrosis 2,6-dinitrotoluene 12.9618551238 7678174
MESH:D019636 Neurodegenerative Diseases Acetaminophen 3.2618514411
MESH:D009784 Occupational Diseases 2,4-dinitrotoluene 10.4112819281 16049721
MESH:D009784 Occupational Diseases 2,6-dinitrotoluene 10.4116049721
MESH:D010146 Pain Acetaminophen 2.7716870215
MESH:D012640 Seizures 2,4-dinitrotoluene 6.8418551238
MESH:D012640 Seizures 2,6-dinitrotoluene 6.8418551238
MESH:D001749 Urinary Bladder Neoplasms 2,4-dinitrotoluene 5.4816049721
MESH:D001749 Urinary Bladder Neoplasms 2,6-dinitrotoluene 5.4816049721
MESH:D014571 Urologic Neoplasms 2,4-dinitrotoluene 14.6010091137
MESH:D014571 Urologic Neoplasms 2,6-dinitrotoluene 14.6010091137
MESH:D014581 Urticaria Acetaminophen 3.5010982225
No data
Pharmacogenomics Knowledge Base Top
  • PharmGKB Accession:PA134921585
  • No data
    Releated disease ID Related disease Name
    PA447216Schizophrenia
    No data
    Drug Bank Top

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      (e.g. CHD8)

    Syndromic Genes

    Non-syndromic Genes

    AutismKB Statistics

    • Studies: 1,036
    • Genes: 1,379
    • CNVs/SVs: 5,420
    • SNVs/Indels: 11,669
    • de novo Mutations: 5,669
    • Mosaics: 789
    • Linkage Regions: 172
    • Paper Collected: 6/30/2018
    • Last Update: 8/26/2018