AutismKB 2.0

Annotation Detail for PSMC1


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Basic Information Top
Gene Symbol:PSMC1 ( MGC24583,MGC8541,P26S4,S4,p56 )
Gene Full Name: proteasome (prosome, macropain) 26S subunit, ATPase, 1
Band: 14q32.11
Quick LinksEntrez ID:5700; OMIM: 602706; Uniprot ID:PRS4_HUMAN; ENSEMBL ID: ENSG00000100764; HGNC ID: 9547
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
No data
Pathway IDPathway Name
hsa03050Proteasome
Pathway IDPathway Name
Signaling by Wnt
Cell Cycle, Mitotic
DNA Replication
Apoptosis
Cdc20:Phospho-APC/C mediated degradation of Cyclin A
HIV Infection
Cell Cycle Checkpoints
Regulation of activated PAK-2p34 by proteasome mediated degradation
Metabolism of amino acids and derivatives
No data
No data
Pathway IDPathway Name
500401Autodegradation of Cdh1 by Cdh1:APC/C
500372SCF(Skp2)-mediated degradation of p27/p21
Related Diseases/Disorders Top
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C049325 1,2-dithiol-3-thione 1,2-dithiol-3-thione results in increased expression of PSMC1 mRNAincreases expression 15375163
C019499 2-nitrofluorene 2-nitrofluorene results in increased expression of PSMC1 mRNAincreases expression 15890375
C009505 4,4'-diaminodiphenylmethane 4,4'-diaminodiphenylmethane results in decreased expression of PSMC1 mRNAdecreases expression 18648102
C016583 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of PSMC1 mRNAincreases expression 15890375
D016604 Aflatoxin B1 Aflatoxin B1 results in increased expression of PSMC1 mRNAincreases expression 15890375
D000638 Amiodarone Amiodarone affects the expression of PSMC1 mRNAaffects expression 19483382
D000643 Ammonium Chloride Ammonium Chloride affects the expression of PSMC1 mRNAaffects expression 16483693
D001553 Benzbromarone Benzbromarone affects the expression of PSMC1 mRNAaffects expression 19483382
D019324 beta-Naphthoflavone beta-Naphthoflavone results in increased expression of PSMC1 mRNAincreases expression 19737606
D002087 Butyrates Butyrates results in increased expression of PSMC1 mRNAincreases expression 14674679
D002713 Chlorine [Ozone co-treated with Chlorine] results in decreased expression of PSMC1 mRNAaffects cotreatment|decreases expression 18636392
D002994 Clofibrate Clofibrate affects the expression of PSMC1 mRNAaffects expression 19483382
D004054 Diethylstilbestrol Diethylstilbestrol results in increased expression of PSMC1 mRNAincreases expression 15890375
D004128 Dimethylnitrosamine Dimethylnitrosamine results in increased expression of PSMC1 mRNAincreases expression 15890375
D004997 Ethinyl Estradiol Ethinyl Estradiol results in increased expression of PSMC1 mRNAincreases expression 17942748
D005001 Ethionine Ethionine affects the expression of PSMC1 mRNAaffects expression 19483382
D007657 Ketone Bodies Ketone Bodies results in increased expression of PSMC1 mRNAincreases expression 16807920
D008701 Methapyrilene Methapyrilene results in decreased expression of PSMC1 mRNAdecreases expression 15890375
D015741 Metribolone Metribolone results in increased expression of PSMC1 proteinincreases expression 17152098
C014707 nitrosobenzylmethylamine nitrosobenzylmethylamine results in increased expression of PSMC1 mRNAincreases expression 17616710
D009853 Omeprazole Omeprazole affects the expression of PSMC1 mRNAaffects expression 19483382
D010126 Ozone [Ozone co-treated with Chlorine] results in decreased expression of PSMC1 mRNAaffects cotreatment|decreases expression 18636392
D010882 Piperonyl Butoxide Piperonyl Butoxide results in increased expression of PSMC1 mRNAincreases expression 15890375
C006253 pirinixic acid pirinixic acid affects the expression of PSMC1 mRNAaffects expression 19483382
C006253 pirinixic acid pirinixic acid results in increased expression of PSMC1 mRNAincreases expression 15890375
D011441 Propylthiouracil Propylthiouracil affects the expression of PSMC1 mRNAaffects expression 19483382
C037219 quinoline quinoline analog results in increased expression of PSMC1 proteinincreases expression 18645022
D012643 Selenium Selenium results in increased expression of PSMC1 mRNAincreases expression 19244175
D013853 Thioacetamide Thioacetamide affects the expression of PSMC1 mRNAaffects expression 19483382
D014810 Vitamin E Vitamin E results in increased expression of PSMC1 mRNAincreases expression 19244175
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000138 Acidosis Ammonium Chloride 3.3018287403
MESH:D000152 Acne Vulgaris Ethinyl Estradiol 3.6817505938
MESH:D055371 Acute Lung Injury Chlorine 8.3420601635
MESH:D055371 Acute Lung Injury pirinixic acid 8.3418653653
MESH:D000230 Adenocarcinoma Dimethylnitrosamine 4.2816033868
MESH:D000230 Adenocarcinoma Ethinyl Estradiol 4.2814692618
MESH:D000236 Adenoma 4,4'-diaminodiphenylmethane 14.833712494
MESH:D000236 Adenoma 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone 14.8316176798
MESH:D000236 Adenoma beta-Naphthoflavone 14.8319389873
MESH:D000236 Adenoma Dimethylnitrosamine 14.8319555203
MESH:D018248 Adenoma, Liver Cell pirinixic acid 3.2216434500
MESH:D000544 Alzheimer Disease Ozone 2.3815513908
MESH:D000686 Amyloidosis Diethylstilbestrol 4.2315469931
MESH:D001145 Arrhythmias, Cardiac Amiodarone 3.5820041841 18218290 18057881
MESH:D001161 Arteriosclerosis Ethinyl Estradiol 3.2111256880
MESH:D001169 Arthritis, Experimental Ethinyl Estradiol 2.5015885639
MESH:D001172 Arthritis, Rheumatoid Ozone 2.5015570426
MESH:D001249 Asthma Ozone 2.5616373670 17854713
MESH:D001281 Atrial Fibrillation Amiodarone 3.7119698954 18651412
MESH:D001660 Biliary Tract Diseases 4,4'-diaminodiphenylmethane 4.751440618 11289319
MESH:D001778 Blood Coagulation Disorders Amiodarone 46.4819483382
MESH:D001778 Blood Coagulation Disorders Benzbromarone 46.4819483382
MESH:D001778 Blood Coagulation Disorders Clofibrate 46.4819483382
MESH:D001778 Blood Coagulation Disorders Ethionine 46.4819483382
MESH:D001778 Blood Coagulation Disorders Omeprazole 46.4819483382
MESH:D001778 Blood Coagulation Disorders pirinixic acid 46.4819483382
MESH:D001778 Blood Coagulation Disorders Propylthiouracil 46.4819483382
MESH:D001778 Blood Coagulation Disorders Thioacetamide 46.4819483382
MESH:D001943 Breast Neoplasms 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone 2.7320146248
MESH:D001943 Breast Neoplasms Diethylstilbestrol 2.7315324884 17129689
MESH:D016535 Bronchial Hyperreactivity Ozone 3.4718315731 15516495 17626835 18417511 19059883 16777450 14754758
MESH:D002100 Cachexia Ozone 4.4816183385
MESH:D002252 Carbon Tetrachloride Poisoning Vitamin E 3.6716050911
MESH:D002277 Carcinoma Dimethylnitrosamine 3.8219555203
MESH:D006528 Carcinoma, Hepatocellular 4,4'-diaminodiphenylmethane 10.823581430 7296757
MESH:D006528 Carcinoma, Hepatocellular Aflatoxin B1 10.8212907637 12619106 21507988
MESH:D006528 Carcinoma, Hepatocellular Benzbromarone 10.821701930
MESH:D006528 Carcinoma, Hepatocellular Diethylstilbestrol 10.8216924424 15948411
MESH:D006528 Carcinoma, Hepatocellular quinoline 10.82598648
MESH:D006528 Carcinoma, Hepatocellular Thioacetamide 10.8217997003
MESH:D002292 Carcinoma, Renal Cell 4,4'-diaminodiphenylmethane 2.557296757
MESH:D002294 Carcinoma, Squamous Cell Dimethylnitrosamine 2.8816033868
MESH:D002311 Cardiomyopathy, Dilated Amiodarone 2.8019225199 15710769
MESH:D002341 Carotid Artery Thrombosis Amiodarone 4.8218974383
MESH:D002471 Cell Transformation, Neoplastic 4,4'-diaminodiphenylmethane 6.347505956
MESH:D002471 Cell Transformation, Neoplastic Clofibrate 6.341399818
MESH:D002637 Chest Pain Omeprazole 4.8415447763
MESH:D018281 Cholangiocarcinoma Thioacetamide 4.0718291259
MESH:D002779 Cholestasis 4,4'-diaminodiphenylmethane 12.2619486331 9022650
MESH:D002779 Cholestasis Ethinyl Estradiol 12.2615861022 16105132 17110522 17681005 17333356 11677210 16919318
MESH:D002779 Cholestasis pirinixic acid 12.2619176532
MESH:D003092 Colitis Selenium 3.5217936198
MESH:D003110 Colonic Neoplasms Butyrates 3.0415936596
MESH:D019465 Craniofacial Abnormalities Vitamin E 1.9019769572
MESH:D003456 Cryptorchidism Diethylstilbestrol 4.3112952375 16002989
MESH:D017449 Dermatitis, Allergic Contact 4,4'-diaminodiphenylmethane 2.568970840 14531868 18759878 12868966 11298694 11906362 2524372 8156756
MESH:D003876 Dermatitis, Atopic pirinixic acid 2.3018249437
MESH:D003877 Dermatitis, Contact 4,4'-diaminodiphenylmethane 3.253621924 2952479
MESH:D056486 Drug-Induced Liver Injury 4,4'-diaminodiphenylmethane 11.1818648102 7440962 6482804 1440618 18289764 9022650 18692083 16192314 11289319 9328219 9653073 6679447 8291058
MESH:D056486 Drug-Induced Liver Injury Amiodarone 11.1815265979 18218290
MESH:D056486 Drug-Induced Liver Injury Dimethylnitrosamine 11.188172417
MESH:D056486 Drug-Induced Liver Injury Selenium 11.1815131321
MESH:D056486 Drug-Induced Liver Injury Thioacetamide 11.1812963478
MESH:D004381 Duodenal Ulcer Omeprazole 4.0817151854 16613094 21218061 15991576
MESH:D050171 Dyslipidemias Clofibrate 3.8816707586
MESH:D004417 Dyspnea Chlorine 4.3620016425
MESH:C538011 Eales disease Vitamin E 4.449068938
MESH:D004487 Edema pirinixic acid 2.2612083418
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Ethinyl Estradiol 2.9412538720
MESH:D004714 Endometrial Hyperplasia Diethylstilbestrol 4.4316402032
MESH:D016889 Endometrial Neoplasms Diethylstilbestrol 3.3016804899 15700306
MESH:D004938 Esophageal Neoplasms 4,4'-diaminodiphenylmethane 6.983581430
MESH:D004938 Esophageal Neoplasms Dimethylnitrosamine 6.9817016578
MESH:D004938 Esophageal Neoplasms nitrosobenzylmethylamine 6.9815623463 15547733 16510608 15264214 16704527 15150132 16805852 15878914 15547721
MESH:D005218 Fat Necrosis Thioacetamide 5.4516456712
MESH:D005234 Fatty Liver Amiodarone 16.8714986274
MESH:D005234 Fatty Liver Clofibrate 16.8719224547
MESH:D005234 Fatty Liver Ethinyl Estradiol 16.8715345470
MESH:D005234 Fatty Liver pirinixic acid 16.8720131406 19236843
MESH:D052776 Female Urogenital Diseases Diethylstilbestrol 3.5016534752 16513791 16611131 15751030 16002989
MESH:D005350 Fibroma 4,4'-diaminodiphenylmethane 4.756705139
MESH:D005739 Gas Poisoning Chlorine 4.7420016425
MESH:D005833 Genital Neoplasms, Female Diethylstilbestrol 4.6816452187
MESH:D006042 Goiter 4,4'-diaminodiphenylmethane 3.797505956
MESH:D006330 Heart Defects, Congenital Vitamin E 2.8516080930
MESH:D006333 Heart Failure pirinixic acid 6.4220558911
MESH:D006333 Heart Failure Selenium 6.4217162251
MESH:D006390 Hemangioendothelioma quinoline 5.64598648
MESH:D006394 Hemangiosarcoma quinoline 4.76598648
MESH:D006501 Hepatic Encephalopathy Thioacetamide 4.3415929193 17276928 18665440
MESH:D006505 Hepatitis 4,4'-diaminodiphenylmethane 8.626705139
MESH:D006505 Hepatitis Thioacetamide 8.6216456712
MESH:D006529 Hepatomegaly Amiodarone 7.7215265979
MESH:D006529 Hepatomegaly pirinixic acid 7.7218467677 19772884 19176532 16221962
MESH:D006548 Hernia, Diaphragmatic Vitamin E 2.6116863852 16490937
MESH:D019584 Hot Flashes Vitamin E 3.7114716179
MESH:D006937 Hypercholesterolemia Amiodarone 3.649751232 8137927
MESH:D006943 Hyperglycemia pirinixic acid 2.9620558911
MESH:D006965 Hyperplasia 4,4'-diaminodiphenylmethane 9.9815034207
MESH:D006965 Hyperplasia Diethylstilbestrol 9.9814722030 12960047
MESH:D007021 Hypospadias Diethylstilbestrol 10.3816002989
MESH:D007021 Hypospadias Ethinyl Estradiol 10.3816945680 16569931
MESH:D007037 Hypothyroidism Amiodarone 10.7517991464 18020914
MESH:D007037 Hypothyroidism Propylthiouracil 10.7518031379 8137927
MESH:D007246 Infertility Diethylstilbestrol 4.1015036965
MESH:D007247 Infertility, Female Ethinyl Estradiol 3.2212013081
MESH:D007248 Infertility, Male Ethinyl Estradiol 2.3217937319
MESH:D007251 Influenza, Human Selenium 10.0716624496
MESH:D007251 Influenza, Human Vitamin E 10.0716624496
MESH:D007333 Insulin Resistance pirinixic acid 2.4616306350
MESH:D007565 Jaundice 4,4'-diaminodiphenylmethane 4.759022650 8074119
MESH:D007674 Kidney Diseases Vitamin E 2.6612488133
MESH:D007676 Kidney Failure, Chronic Selenium 3.6516518626
MESH:D007680 Kidney Neoplasms 4,4'-diaminodiphenylmethane 6.846582329
MESH:D007680 Kidney Neoplasms Diethylstilbestrol 6.8414681315 15003126 16762066
MESH:D007859 Learning Disorders Diethylstilbestrol 3.8117184923
MESH:D016773 Leishmaniasis, Cutaneous Omeprazole 3.8919248655
MESH:D008064 Lipidoses Amiodarone 3.3215342952 17567588
MESH:D008105 Liver Cirrhosis, Biliary 4,4'-diaminodiphenylmethane 3.0315034207 9327722
MESH:D008106 Liver Cirrhosis, Experimental Dimethylnitrosamine 4.7416627068 16570917 15798949 17432682 17198567 16042886 14643895 15763062 17465448 15723089 18637143 15793283 15479170 14659978 17534399 15744066 17724770 17640959 14726149 16270385 15099470 15086199 15161499 15298665 15577212 18237412 17201889 14709902 15571005 12925901 14568256 15067225 18239293 15339415 15369754 18095165 16009107 18629640 17719030 17196135 15383259 18364076 18567088 15591649 16169303 15504291 15081153 18672772 16544323 16603200 18210741 15492853 17666798 17036385 15864749 18371158 17203207 15138612 15366600 17881167 17348192 15733078 12918455 15942678 15842777
MESH:D008106 Liver Cirrhosis, Experimental pirinixic acid 4.7415474484
MESH:D008106 Liver Cirrhosis, Experimental Thioacetamide 4.7416489207 16098781 16097051 15474484 12085344 11682029 15362042 11481614 15288472 18416461 12175628 18032466 18606216 17292413 18263696 16126171 12557150 15158331 15465738 15095483 17050028 11172339 16343077 15716488 17355460 16248980 10677585 15288473 18395095 15334695 16511523 15078482 17127702 12679928 12891558 17629604 18615449 18295389 12531686 15316131 15075984 18031379 18458672 18380797 14739098
MESH:D008106 Liver Cirrhosis, Experimental Vitamin E 4.7416169303
MESH:D008107 Liver Diseases Thioacetamide 2.6418374380 15158337 16337175
MESH:D017114 Liver Failure, Acute Dimethylnitrosamine 9.3117457977
MESH:D017114 Liver Failure, Acute Thioacetamide 9.3115633222 17276928 12479984 15313186
MESH:D008113 Liver Neoplasms 2-nitrofluorene 28.1615890375
MESH:D008113 Liver Neoplasms 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone 28.1615890375
MESH:D008113 Liver Neoplasms Aflatoxin B1 28.162125692 15890375 9163691 18177683
MESH:D008113 Liver Neoplasms beta-Naphthoflavone 28.1621295105 19389873
MESH:D008113 Liver Neoplasms Diethylstilbestrol 28.1615890375 16712894
MESH:D008113 Liver Neoplasms Dimethylnitrosamine 28.1615890375 3113478
MESH:D008113 Liver Neoplasms Methapyrilene 28.1615890375
MESH:D008113 Liver Neoplasms Piperonyl Butoxide 28.1618648771 19690152 20101389 15890375
MESH:D008113 Liver Neoplasms pirinixic acid 28.1615890375 16377806 20007298
MESH:D008114 Liver Neoplasms, Experimental 4,4'-diaminodiphenylmethane 12.85598648 6587162 3712494 1399818
MESH:D008114 Liver Neoplasms, Experimental Aflatoxin B1 12.858603461
MESH:D008114 Liver Neoplasms, Experimental beta-Naphthoflavone 12.8518164116
MESH:D008114 Liver Neoplasms, Experimental Dimethylnitrosamine 12.851848544 6150874 15603536
MESH:D008133 Long QT Syndrome Amiodarone 3.3815350150 11989578 17391786
MESH:D008171 Lung Diseases Amiodarone 11.3812587719
MESH:D008171 Lung Diseases Ozone 11.388266340 19066396
MESH:D008171 Lung Diseases Vitamin E 11.3816863852
MESH:D017563 Lung Diseases, Interstitial Amiodarone 4.2118516814
MESH:D055370 Lung Injury Ozone 3.5920417186
MESH:D008175 Lung Neoplasms 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone 6.2616061637 15172992 18813816 15893417 12438228 18508827 9255578 19931552 14755239 17139156 16401635
MESH:D008175 Lung Neoplasms Aflatoxin B1 6.2614755239
MESH:D008175 Lung Neoplasms Dimethylnitrosamine 6.2611884234 16061637 19555203
MESH:D008175 Lung Neoplasms Ozone 6.267614698 8597069
MESH:D008175 Lung Neoplasms Vitamin E 6.2611062179
MESH:D008181 Lupus Nephritis Diethylstilbestrol 4.8915166399
MESH:D008223 Lymphoma Diethylstilbestrol 3.2915700306
MESH:D052801 Male Urogenital Diseases Diethylstilbestrol 5.2516002989
MESH:D008325 Mammary Neoplasms, Experimental Selenium 2.6015318939
MESH:D008654 Mesothelioma Selenium 2.6915107826
MESH:D008679 Metaplasia Ozone 4.8410496685
MESH:D009135 Muscular Diseases pirinixic acid 3.2516239165
MESH:D009181 Mycoses Amiodarone 4.6312754197 17974566
MESH:D009203 Myocardial Infarction pirinixic acid 2.0319151258
MESH:D015428 Myocardial Reperfusion Injury pirinixic acid 2.7516411023
MESH:D009362 Neoplasm Metastasis 4,4'-diaminodiphenylmethane 5.893581430
MESH:D009362 Neoplasm Metastasis quinoline 5.89598648
MESH:D009369 Neoplasms Diethylstilbestrol 4.6115313581
MESH:D009369 Neoplasms pirinixic acid 4.6117405874
MESH:D009421 Nervous System Malformations Diethylstilbestrol 3.8911399458
MESH:D009436 Neural Tube Defects 4,4'-diaminodiphenylmethane 2.756679447
MESH:D052556 Niemann-Pick Disease, Type C Clofibrate 4.689802331
MESH:D009765 Obesity pirinixic acid 1.7520558911
MESH:D009784 Occupational Diseases 4,4'-diaminodiphenylmethane 3.194026338 6482804
MESH:D009902 Optic Neuritis 4,4'-diaminodiphenylmethane 4.753988306
MESH:D010190 Pancreatic Neoplasms 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone 3.3512384795
MESH:D016584 Panic Disorder Ethinyl Estradiol 3.4411578682
MESH:D010212 Papilloma 4,4'-diaminodiphenylmethane 3.237296757
MESH:D010538 Peritonitis Ozone 3.8716369182
MESH:D010787 Photosensitivity Disorders 4,4'-diaminodiphenylmethane 4.206228378
MESH:D010900 Pituitary Diseases Diethylstilbestrol 4.9014722030
MESH:D010911 Pituitary Neoplasms Diethylstilbestrol 4.4116977796 15687265
MESH:D010954 Plasmacytoma Selenium 4.6215087411
MESH:D011014 Pneumonia Ozone 4.1318381685 18007984 18929643
MESH:D011297 Prenatal Exposure Delayed Effects Diethylstilbestrol 3.8517184923
MESH:D011471 Prostatic Neoplasms Diethylstilbestrol 3.5015846301 15046698 17136230
MESH:D011471 Prostatic Neoplasms Vitamin E 3.5015084515
MESH:D011537 Pruritus Ethinyl Estradiol 3.0516919318 15861022
MESH:D011658 Pulmonary Fibrosis Amiodarone 2.7512490602 12832656 11597910
MESH:D015427 Reperfusion Injury pirinixic acid 2.2619058328
MESH:D012120 Respiration Disorders Chlorine 4.9518579056
MESH:D012162 Retinal Degeneration 4,4'-diaminodiphenylmethane 3.183692021
OMIM:609620 SHORT QT SYNDROME 1 Amiodarone 4.8218724381
MESH:D012871 Skin Diseases Vitamin E 2.3718709164
MESH:D013088 Spermatocele Diethylstilbestrol 10.8216002989 16709447
MESH:D013088 Spermatocele Ethinyl Estradiol 10.8216709447
MESH:D013158 Splenic Diseases Dimethylnitrosamine 5.0012587719
MESH:D013272 Stomach Diseases Omeprazole 4.3518545984
MESH:D013274 Stomach Neoplasms Dimethylnitrosamine 2.8016033868
MESH:D013274 Stomach Neoplasms nitrosobenzylmethylamine 2.8017575124 12958204
MESH:D013276 Stomach Ulcer Amiodarone 6.8018087811
MESH:D013276 Stomach Ulcer Omeprazole 6.8011906479 18237397 16755016 10750652 15991576 17977527
MESH:D020521 Stroke Vitamin E 3.3216517955
MESH:D013610 Tachycardia Amiodarone 4.0411238279
MESH:D017180 Tachycardia, Ventricular Amiodarone 3.9419225199
MESH:D019851 Thrombophilia Ethinyl Estradiol 3.3811994571
MESH:D013927 Thrombosis Ethinyl Estradiol 2.9315669648
MESH:D013959 Thyroid Diseases Amiodarone 4.4919731979
MESH:D013964 Thyroid Neoplasms 4,4'-diaminodiphenylmethane 11.041399818 6582329 7505956 3712494 6587162
MESH:D013964 Thyroid Neoplasms Butyrates 11.0417967635
MESH:D013964 Thyroid Neoplasms Propylthiouracil 11.0415710170
MESH:D013971 Thyrotoxicosis Amiodarone 4.6018020914 19584973
MESH:D016171 Torsades de Pointes Amiodarone 3.9317467628 11989578
MESH:D001749 Urinary Bladder Neoplasms 4,4'-diaminodiphenylmethane 4.848074119
MESH:D001749 Urinary Bladder Neoplasms Diethylstilbestrol 4.8416712894 16452187 17306315
MESH:D002583 Uterine Cervical Neoplasms Diethylstilbestrol 3.8116175088
MESH:D014591 Uterine Diseases Diethylstilbestrol 4.9014652134
MESH:D014594 Uterine Neoplasms Diethylstilbestrol 8.6415809267 16690809
MESH:D014594 Uterine Neoplasms Ethinyl Estradiol 8.6414692618
MESH:D014625 Vaginal Neoplasms Diethylstilbestrol 4.1816002989 16513791
MESH:D020246 Venous Thrombosis Ethinyl Estradiol 3.3015869587 14671159
Pathway ID Pathway Name
REACT:578 Apoptosis
REACT:6850 Cdc20:Phospho-APC/C mediated degradation of Cyclin A
REACT:1538 Cell Cycle Checkpoints
REACT:152 Cell Cycle, Mitotic
REACT:383 DNA Replication
REACT:6185 HIV Infection
REACT:13 Metabolism of amino acids and derivatives
REACT:21257 Metabolism of RNA
KEGG:03050 Proteasome
REACT:13505 Proteasome mediated degradation of PAK-2p34
REACT:11045 Signaling by Wnt
Pharmacogenomics Knowledge Base Top
Drug Bank Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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