Annotation Detail for RARS2

Basic Information
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Gene Symbol: | RARS2 ( ArgRS,DALRD2,MGC14993,MGC23778,PCH6,PRO1992,RARSL,dJ382I10.6 ) |
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Gene Full Name: | arginyl-tRNA synthetase 2, mitochondrial |
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Band: | 6q15 |
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Quick Links | Entrez ID:57038; OMIM: 611524; Uniprot ID:SYRM_HUMAN; ENSEMBL ID: ENSG00000146282; HGNC ID: 21406 |
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Relate to Another Database: |
SFARIGene;
denovo-db |
Pathway ID | Pathway Name |
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hsa00970 | Aminoacyl-tRNA biosynthesis |
Pathway ID | Pathway Name |
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| Gene Expression |
Pathway ID | Pathway Name |
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500661 | Mitochondrial tRNA aminoacylation |
Desease Name |
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Pontocerebellar hypoplasia, type 6 |
Chemical ID |
Chemical Name |
Interaction |
Interaction Action |
Publication |
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D015123 |
7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide |
7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in decreased expression of RARS2 mRNA | decreases expression | 20018196
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D011374 |
Progesterone |
Progesterone affects the expression of RARS2 mRNA | affects expression | 17251523
|
C034028 |
vanadyl sulfate |
vanadyl sulfate results in increased expression of RARS2 mRNA | increases expression | 16330358
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Disease ID |
Disease Name |
Direct Evidence |
Inference Chemical Name |
Inference Score |
Publication |
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MESH:D020201 |
Brain Hemorrhage, Traumatic |
|
Progesterone |
6.20 | 17868700 |
MESH:D001930 |
Brain Injuries |
|
Progesterone |
4.91 | 15665606 15380490 15845082 |
MESH:D001943 |
Breast Neoplasms |
|
Progesterone |
2.41 | 17614352 15562024 16175315 |
MESH:D002471 |
Cell Transformation, Neoplastic |
|
7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide |
3.01 | 20889678 |
MESH:D003921 |
Diabetes Mellitus, Experimental |
|
vanadyl sulfate |
4.76 | 16684804 |
MESH:D003929 |
Diabetic Neuropathies |
|
Progesterone |
5.15 | 17187935 |
MESH:D004681 |
Encephalomyelitis, Autoimmune, Experimental |
|
Progesterone |
4.36 | 17692515 |
MESH:D004715 |
Endometriosis |
|
Progesterone |
4.21 | 16134523 |
MESH:D004938 |
Esophageal Neoplasms |
|
7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide |
2.15 | 20426865 |
MESH:D020244 |
Infarction, Middle Cerebral Artery |
|
Progesterone |
5.05 | 15869954 |
MESH:D007249 |
Inflammation |
|
Progesterone |
2.79 | 15869954 |
MESH:D008325 |
Mammary Neoplasms, Experimental |
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Progesterone |
3.12 | 17203775 11408345 |
MESH:D010051 |
Ovarian Neoplasms |
|
Progesterone |
2.63 | 16525653 17393432 |
MESH:C548074 |
Pontocerebellar Hypoplasia Type 6 |
marker/mechanism |
|
| |
MESH:D012468 |
Salivary Gland Neoplasms |
|
Progesterone |
2.97 | 18045962 |
MESH:D013119 |
Spinal Cord Injuries |
|
Progesterone |
5.02 | 16503802 15862959 |