AutismKB 2.0

Annotation Detail for CASC5


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Basic Information Top
Gene Symbol:CASC5 ( AF15Q14,CT29,D40,KIAA1570,KNL1,hKNL-1,hSpc105 )
Gene Full Name: cancer susceptibility candidate 5
Band: 15q14
Quick LinksEntrez ID:57082; OMIM: 609173; Uniprot ID:CASC5_HUMAN; ENSEMBL ID: ENSG00000137812; HGNC ID:
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
No data
No data
Pathway IDPathway Name
Cell Cycle, Mitotic
DNA Replication
Chromosome Maintenance
No data
No data
No data
Related Diseases/Disorders Top
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
D015123 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in decreased expression of CASC5 mRNAdecreases expression 19150397
20382639
D015741 Metribolone Metribolone results in increased expression of CASC5 mRNAincreases expression 17010196
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D002471 Cell Transformation, Neoplastic 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 3.0420889678
MESH:D004938 Esophageal Neoplasms 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 2.1620426865
Pathway ID Pathway Name
REACT:152 Cell Cycle, Mitotic
REACT:22172 Chromosome Maintenance
REACT:383 DNA Replication
Pharmacogenomics Knowledge Base Top
  • PharmGKB Accession:PA142672201
  • No data
    Releated disease ID Related disease Name
    PA443560Breast Neoplasms
    No data
    Drug Bank Top

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    Syndromic Genes

    Non-syndromic Genes

    AutismKB Statistics

    • Studies: 1,036
    • Genes: 1,379
    • CNVs/SVs: 5,420
    • SNVs/Indels: 11,669
    • de novo Mutations: 5,669
    • Mosaics: 789
    • Linkage Regions: 172
    • Paper Collected: 6/30/2018
    • Last Update: 8/26/2018