Gene Symbol:	C12orf4 ( FLJ21158,FLJ23899 )
Gene Full Name:	chromosome 12 open reading frame 4
Band:	12p13.32
Quick Links	Entrez ID:57102; OMIM: NA; Uniprot ID:CL004_HUMAN; ENSEMBL ID: ENSG00000047621; HGNC ID: 1184
Relate to Another Database:	SFARIGene; denovo-db

Chemical ID	Chemical Name	Interaction	Interaction Action	Publication
D001564	Benzo(a)pyrene	Benzo(a)pyrene results in decreased expression of C12ORF4 mRNA	decreases expression	20064835
D016572	Cyclosporine	Cyclosporine results in increased expression of C12ORF4 mRNA	increases expression	20106945
C011890	kojic acid	kojic acid results in decreased expression of C12ORF4 mRNA	decreases expression	16595896
D014810	Vitamin E	Vitamin E results in decreased expression of C12ORF4 mRNA	decreases expression	19244175

Disease ID	Disease Name	Inference Chemical Name	Inference Score	Publication
MESH:D000230	Adenocarcinoma	Benzo(a)pyrene	2.06	20127859 20464547
MESH:D000236	Adenoma	Benzo(a)pyrene	2.86	6695378
MESH:D017544	Aortic Aneurysm, Abdominal	Benzo(a)pyrene	4.64	19183758
MESH:D001943	Breast Neoplasms	Benzo(a)pyrene	1.99	20146248 17474063
MESH:D002252	Carbon Tetrachloride Poisoning	Vitamin E	4.49	16050911
MESH:D002294	Carcinoma, Squamous Cell	Benzo(a)pyrene	2.13	20419170
MESH:D002471	Cell Transformation, Neoplastic	Cyclosporine	2.79	12371664
MESH:D002779	Cholestasis	Cyclosporine	3.21	19486331
MESH:D019465	Craniofacial Abnormalities	Vitamin E	1.93	19769572
MESH:C538011	Eales disease	Vitamin E	5.43	9068938
MESH:D004938	Esophageal Neoplasms	Benzo(a)pyrene	2.08	16530937
MESH:D005234	Fatty Liver	Cyclosporine	3.28	19224547
MESH:D005355	Fibrosis	Cyclosporine	3.70	12168785 12639820
MESH:D005885	Gingival Hyperplasia	Cyclosporine	4.85	8708960
MESH:D006330	Heart Defects, Congenital	Benzo(a)pyrene	7.29	20471113
MESH:D006330	Heart Defects, Congenital	Vitamin E	7.29	16080930
MESH:D006457	Hemoglobinuria, Paroxysmal	Cyclosporine	5.05	15720958
MESH:D006548	Hernia, Diaphragmatic	Vitamin E	2.81	16863852 16490937
MESH:D019584	Hot Flashes	Vitamin E	4.69	14716179
MESH:D006973	Hypertension	Cyclosporine	2.21	10903974
MESH:D007251	Influenza, Human	Vitamin E	4.94	16624496
MESH:D007638	Keratoconjunctivitis Sicca	Cyclosporine	5.16	15604871
MESH:D007674	Kidney Diseases	Cyclosporine	6.70	18776723 10903974 8314463
MESH:D007674	Kidney Diseases	Vitamin E	6.70	12488133
MESH:D007680	Kidney Neoplasms	Cyclosporine	3.08	12371664
MESH:D008106	Liver Cirrhosis, Experimental	Vitamin E	1.91	16169303
MESH:D008113	Liver Neoplasms	Benzo(a)pyrene	2.15	21137059 20195826
MESH:D008114	Liver Neoplasms, Experimental	kojic acid	3.55	18544905
MESH:D008171	Lung Diseases	Vitamin E	3.43	16863852
MESH:D008175	Lung Neoplasms	Benzo(a)pyrene	2.51	17053015 18816296 20464547 18569708 20064080 20869020 20135361 18520028 6695378
MESH:D008175	Lung Neoplasms	Vitamin E	2.51	11062179
MESH:D008664	Metal Metabolism, Inborn Errors	Cyclosporine	5.51	16801185
MESH:D009062	Mouth Neoplasms	Benzo(a)pyrene	3.50	16381670
MESH:D009369	Neoplasms	Benzo(a)pyrene	2.33	11141357
MESH:D009402	Nephrosis, Lipoid	Cyclosporine	5.16	17954296
MESH:D009404	Nephrotic Syndrome	Cyclosporine	3.65	18481113 19348381
MESH:D011230	Precancerous Conditions	Cyclosporine	3.59	12371664
MESH:D011471	Prostatic Neoplasms	Benzo(a)pyrene	3.11	17292933
MESH:D011471	Prostatic Neoplasms	Vitamin E	3.11	15084515
MESH:D011565	Psoriasis	Cyclosporine	2.33	16882103
MESH:D012871	Skin Diseases	Vitamin E	2.52	18709164
MESH:D012878	Skin Neoplasms	Benzo(a)pyrene	2.52	10029692 19755658
MESH:D013274	Stomach Neoplasms	Benzo(a)pyrene	1.56	20155912 2093021
MESH:D020521	Stroke	Vitamin E	3.84	16517955
MESH:D001749	Urinary Bladder Neoplasms	Benzo(a)pyrene	2.30	17053015
MESH:D014605	Uveitis	Cyclosporine	4.71	1336536
MESH:D014985	Xerophthalmia	Cyclosporine	5.16	17120751

AutismKB 2.0

Annotation Detail for C12orf4

Simple Query:

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics