Annotation Detail for PDSS2
Basic Information Top
| Gene Symbol: | PDSS2 ( C6orf210,DLP1,bA59I9.3,hDLP1 ) |
|---|---|
| Gene Full Name: | prenyl (decaprenyl) diphosphate synthase, subunit 2 |
| Band: | 6q21 |
| Quick Links | Entrez ID:57107; OMIM: 610564; Uniprot ID:DLP1_HUMAN; ENSEMBL ID: ENSG00000164494; HGNC ID: 23041 |
| Relate to Another Database: | SFARIGene; denovo-db |
| Pathway ID | Pathway Name |
|---|---|
| PWY-5120 | geranylgeranyldiphosphate biosynthesis |
| PWY-5910 | superpathway of geranylgeranyldiphosphate biosynthesis I (via mevalonate) |
| PWY-5806 | all-trans-decaprenyl diphosphate biosynthesis |
| HEXPPSYN-PWY | hexaprenyl diphosphate biosynthesis |
| Pathway ID | Pathway Name |
|---|---|
| hsa00900 | Terpenoid backbone biosynthesis |
| No data |
| No data |
| No data |
| No data |
| No data |
| No data |
| No data |
| No data |
| Desease Name |
|---|
| Coenzyme Q10 deficiency |
| Chemical ID | Chemical Name | Interaction | Interaction Action | Publication |
|---|---|---|---|---|
| D016604 | Aflatoxin B1 | Aflatoxin B1 affects the expression of PDSS2 protein | affects expression | 20106945 |
| D016718 | Arachidonic Acid | Arachidonic Acid results in decreased expression of PDSS2 mRNA | decreases expression | 16704987 |
| D001564 | Benzo(a)pyrene | Benzo(a)pyrene results in decreased expression of PDSS2 mRNA | decreases expression | 20106945 20064835 |
| D012643 | Selenium | Selenium results in decreased expression of PDSS2 mRNA | decreases expression | 19244175 |
| C034613 | triacsin C | triacsin C results in decreased expression of PDSS2 mRNA | decreases expression | 16704987 |
| Disease ID | Disease Name | Direct Evidence | Inference Chemical Name | Inference Score | Publication |
|---|---|---|---|---|---|
| MESH:D000230 | Adenocarcinoma | Benzo(a)pyrene | 2.05 | 20464547 20127859 | |
| MESH:D000236 | Adenoma | Benzo(a)pyrene | 2.84 | 6695378 | |
| MESH:D017544 | Aortic Aneurysm, Abdominal | Benzo(a)pyrene | 4.56 | 19183758 | |
| MESH:D001321 | Autistic Disorder | Arachidonic Acid | 3.01 | 18582451 | |
| MESH:D001943 | Breast Neoplasms | Benzo(a)pyrene | 2.00 | 20146248 17474063 | |
| MESH:D006528 | Carcinoma, Hepatocellular | Aflatoxin B1 | 1.98 | 12907637 21507988 12619106 | |
| MESH:D002294 | Carcinoma, Squamous Cell | Benzo(a)pyrene | 2.13 | 20419170 | |
| OMIM:607426 | COENZYME Q10 DEFICIENCY | marker/mechanism | |||
| MESH:D003092 | Colitis | Selenium | 4.26 | 17936198 | |
| MESH:D056486 | Drug-Induced Liver Injury | Selenium | 2.25 | 15131321 | |
| MESH:D004487 | Edema | Arachidonic Acid | 4.40 | 9831321 15177302 16716910 9599246 7990266 11698051 | |
| MESH:D004938 | Esophageal Neoplasms | Benzo(a)pyrene | 2.07 | 16530937 | |
| MESH:D005334 | Fever | Arachidonic Acid | 5.00 | 11852909 | |
| MESH:D006330 | Heart Defects, Congenital | Benzo(a)pyrene | 2.82 | 20471113 | |
| MESH:D006333 | Heart Failure | Selenium | 3.27 | 17162251 | |
| MESH:D007249 | Inflammation | Arachidonic Acid | 3.67 | 9831321 15177302 17371808 | |
| MESH:D007251 | Influenza, Human | Selenium | 4.81 | 16624496 | |
| MESH:D007676 | Kidney Failure, Chronic | Selenium | 4.26 | 16518626 | |
| MESH:D008113 | Liver Neoplasms | Aflatoxin B1 | 4.93 | 18177683 9163691 2125692 15890375 | |
| MESH:D008113 | Liver Neoplasms | Benzo(a)pyrene | 4.93 | 20195826 21137059 | |
| MESH:D008114 | Liver Neoplasms, Experimental | Aflatoxin B1 | 2.94 | 8603461 | |
| MESH:D008175 | Lung Neoplasms | Aflatoxin B1 | 2.50 | 14755239 | |
| MESH:D008175 | Lung Neoplasms | Benzo(a)pyrene | 2.50 | 20464547 18569708 18816296 20064080 17053015 20135361 6695378 18520028 20869020 | |
| MESH:D008325 | Mammary Neoplasms, Experimental | Selenium | 2.97 | 15318939 | |
| MESH:D008654 | Mesothelioma | Selenium | 2.90 | 15107826 | |
| MESH:D009062 | Mouth Neoplasms | Benzo(a)pyrene | 3.46 | 16381670 | |
| MESH:D009369 | Neoplasms | Benzo(a)pyrene | 2.31 | 11141357 | |
| MESH:D010954 | Plasmacytoma | Selenium | 5.50 | 15087411 | |
| MESH:D011471 | Prostatic Neoplasms | Benzo(a)pyrene | 2.91 | 17292933 | |
| MESH:D012878 | Skin Neoplasms | Benzo(a)pyrene | 2.51 | 19755658 10029692 | |
| MESH:D013274 | Stomach Neoplasms | Benzo(a)pyrene | 1.56 | 20155912 2093021 | |
| MESH:D001749 | Urinary Bladder Neoplasms | Benzo(a)pyrene | 2.29 | 17053015 |
| Pathway ID | Pathway Name |
|---|---|
| KEGG:00900 | Terpenoid backbone biosynthesis |
| No data |
| Releated disease ID | Related disease Name |
|---|---|
| PA444997 | Muscular Diseases |
| PA157379134 | Myalgia unspecified |
| No data |
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