AutismKB 2.0

Annotation Detail for CD177


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Basic Information Top
Gene Symbol:CD177 ( HNA2A,NB1,PRV1 )
Gene Full Name: CD177 molecule
Band: 19q13.31
Quick LinksEntrez ID:57126; OMIM: 162860; Uniprot ID:CD177_HUMAN; ENSEMBL ID: ; HGNC ID: 30072
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
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Pathway IDPathway Name
Hemostasis
No data
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Pathway IDPathway Name
500305Cell surface interactions at the vascular wall
Related Diseases/Disorders Top
No data
Desease IDDesease Name
2188Bone marrow disease
2201Myeloproliferative disease
No data
No data
No data
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
D001151 Arsenic Arsenic results in increased expression of CD177 mRNAincreases expression 19654921
C006632 arsenic trioxide arsenic trioxide results in increased expression of CD177 mRNAincreases expression 20458559
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000230 Adenocarcinoma arsenic trioxide 2.3719825857 11798837
MESH:D018246 Adrenocortical Adenoma Arsenic 6.2817306315
MESH:D020261 Arsenic Poisoning Arsenic 2.9716835338 12569548 18414634 16251483
MESH:D050197 Atherosclerosis Arsenic 3.5119371607 12928151
MESH:D001778 Blood Coagulation Disorders arsenic trioxide 4.2216206674
MESH:D002051 Burkitt Lymphoma arsenic trioxide 4.9411589617
MESH:D002280 Carcinoma, Basal Cell Arsenic 3.8317687452 15504454
MESH:D006528 Carcinoma, Hepatocellular Arsenic 3.3916507464 17306315
MESH:D006528 Carcinoma, Hepatocellular arsenic trioxide 3.3916217749 15553829 14691202 11135700 15073043
MESH:D002291 Carcinoma, Papillary arsenic trioxide 5.9419014326
MESH:D018288 Carcinoma, Small Cell arsenic trioxide 4.6312490120
MESH:D002294 Carcinoma, Squamous Cell Arsenic 2.7918922899 17687452 15504454
MESH:D002295 Carcinoma, Transitional Cell Arsenic 4.5818640142
MESH:D002318 Cardiovascular Diseases Arsenic 3.7719152805 17938729 15738583
MESH:D002340 Carotid Artery Diseases Arsenic 4.7818022660 16973168
MESH:D015179 Colorectal Neoplasms arsenic trioxide 1.8720501625
MESH:D023903 Coronary Restenosis arsenic trioxide 4.8612609071
MESH:D019465 Craniofacial Abnormalities arsenic trioxide 1.9010525206
MESH:D016757 Death, Sudden, Cardiac arsenic trioxide 4.7015213294
MESH:D004938 Esophageal Neoplasms arsenic trioxide 2.4012903497
MESH:D005234 Fatty Liver arsenic trioxide 3.8415073043
MESH:D005534 Foot Diseases Arsenic 6.636392382
MESH:D005706 Gallbladder Neoplasms arsenic trioxide 4.9416904648
MESH:D017488 Hyperkeratosis, Epidermolytic Arsenic 4.9617050553
MESH:D006973 Hypertension Arsenic 3.019931084 11953799 16076760
MESH:D006987 Hypesthesia Arsenic 6.6316093927
MESH:D007642 Keratosis Arsenic 5.8816930632 12749816
MESH:D007938 Leukemia arsenic trioxide 3.0315070760
MESH:D015459 Leukemia-Lymphoma, Adult T-Cell arsenic trioxide 4.3512560223 17077332
MESH:D007948 Leukemia, Monocytic, Acute arsenic trioxide 5.1916972261
MESH:D015464 Leukemia, Myelogenous, Chronic, BCR-ABL Positive arsenic trioxide 3.7914633726
MESH:D007951 Leukemia, Myeloid arsenic trioxide 4.3119077051
MESH:D015470 Leukemia, Myeloid, Acute arsenic trioxide 2.1920471514 16968895 16467208 17050201 19850784
MESH:D015473 Leukemia, Promyelocytic, Acute Arsenic 8.7817339181
MESH:D015473 Leukemia, Promyelocytic, Acute arsenic trioxide 8.7816966277 17869043 19035177 15622746 16112521 12018890 17107899 16330433 16823087 12679006 11161223 17712046 19225113 17217047 19642359 15336539 11468182 12712474 15213294 9834237 19075265 15748426 16891316 16331271 17649720
MESH:D015458 Leukemia, T-Cell arsenic trioxide 5.0316882451
MESH:D008107 Liver Diseases Arsenic 2.6311134558
MESH:D008113 Liver Neoplasms Arsenic 5.2816368122
MESH:D008113 Liver Neoplasms arsenic trioxide 5.2814682389
MESH:D008114 Liver Neoplasms, Experimental arsenic trioxide 3.0120377131
MESH:D008133 Long QT Syndrome arsenic trioxide 3.7315213294
MESH:D008175 Lung Neoplasms Arsenic 2.7517976673 17306315 19168569
MESH:D008175 Lung Neoplasms arsenic trioxide 2.7511798837 19825857
MESH:D009101 Multiple Myeloma arsenic trioxide 3.4419549372 19417148 11468182 14977855 15949261
MESH:D009182 Mycosis Fungoides arsenic trioxide 5.7418349030
MESH:D009190 Myelodysplastic Syndromes arsenic trioxide 3.3816105982 16882451
MESH:D017202 Myocardial Ischemia Arsenic 4.3915371236
MESH:D009361 Neoplasm Invasiveness arsenic trioxide 4.6316624393
MESH:D009436 Neural Tube Defects Arsenic 8.4516620997
MESH:D009436 Neural Tube Defects arsenic trioxide 8.4510525206
MESH:D020078 Neurogenic Inflammation Arsenic 4.9817056641
MESH:D010051 Ovarian Neoplasms Arsenic 5.4117306315
MESH:D010051 Ovarian Neoplasms arsenic trioxide 5.4116624393 19769630 12452020
MESH:D010190 Pancreatic Neoplasms arsenic trioxide 2.6615580305
MESH:D010235 Paraganglioma arsenic trioxide 4.7719927285
MESH:D010523 Peripheral Nervous System Diseases Arsenic 4.8516093927
MESH:D016491 Peripheral Vascular Diseases Arsenic 5.8816905509 6392382 15371236
MESH:D011471 Prostatic Neoplasms Arsenic 3.3216140617
MESH:D011471 Prostatic Neoplasms arsenic trioxide 3.3219131511
MESH:D011507 Proteinuria Arsenic 4.6121343184
MESH:D012512 Sarcoma, Ewing's arsenic trioxide 4.6316646077
MESH:D012871 Skin Diseases Arsenic 2.8419834688 17938729 15952646 17453740 18709164 17548696 16702368 16353154 6392382 17050553 16759981
MESH:D012878 Skin Neoplasms Arsenic 3.1919538983 17029826 15504454 17050553 17976673 16251483
MESH:D013274 Stomach Neoplasms arsenic trioxide 1.8617007042
MESH:D013964 Thyroid Neoplasms arsenic trioxide 3.4719014326
MESH:D016171 Torsades de Pointes arsenic trioxide 4.8515213294
MESH:D001749 Urinary Bladder Neoplasms Arsenic 5.7817306315 19429237 19322015 18640142 11144890 17976673 15987713
MESH:D001749 Urinary Bladder Neoplasms arsenic trioxide 5.7812845720 20435036 12973940 11780464
MESH:D014652 Vascular Diseases Arsenic 5.6217056641
Pathway ID Pathway Name
REACT:604 Hemostasis
Pharmacogenomics Knowledge Base Top
  • PharmGKB Accession:PA142672147
    • No data
    No data
    Releated drug ID Related drug Name
    PA450952phospholipids
    Drug Bank Top

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    Syndromic Genes

    Non-syndromic Genes

    AutismKB Statistics

    • Studies: 1,036
    • Genes: 1,379
    • CNVs/SVs: 5,420
    • SNVs/Indels: 11,669
    • de novo Mutations: 5,669
    • Mosaics: 789
    • Linkage Regions: 172
    • Paper Collected: 6/30/2018
    • Last Update: 8/26/2018


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