AutismKB 2.0

Annotation Detail for SALL4


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Basic Information Top
Gene Symbol:SALL4 ( DRRS,HSAL4,MGC133050,ZNF797,dJ1112F19.1 )
Gene Full Name: sal-like 4 (Drosophila)
Band: 20q13.2
Quick LinksEntrez ID:57167; OMIM: 607343; Uniprot ID:SALL4_HUMAN; ENSEMBL ID: ENSG00000101115; HGNC ID: 15924
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
No data
No data
No data
Pathway IDPathway Name
200106Regulation of Wnt-mediated beta catenin signaling and target gene transcription
No data
No data
Related Diseases/Disorders Top
No data
Desease IDDesease Name
1832Congenital abnormality
2051Leukemia
2150Duane retraction syndrome
2207Deafness
Desease Name
CHEMDEPENDENCY
male infertility
smoking cessation
REPRODUCTION
Desease Name
Male infertility
Desease Name
Duane-radial ray syndrome
IVIC syndrome
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C009505 4,4'-diaminodiphenylmethane 4,4'-diaminodiphenylmethane results in increased expression of SALL4 mRNAincreases expression 18648102
D001374 Azacitidine Azacitidine affects the methylation of SALL4 promoteraffects methylation 17546590
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000236 Adenoma 4,4'-diaminodiphenylmethane 3.003712494
MESH:D001660 Biliary Tract Diseases 4,4'-diaminodiphenylmethane 6.091440618 11289319
MESH:D006528 Carcinoma, Hepatocellular 4,4'-diaminodiphenylmethane 1.783581430 7296757
MESH:D002292 Carcinoma, Renal Cell 4,4'-diaminodiphenylmethane 2.867296757
MESH:D002471 Cell Transformation, Neoplastic 4,4'-diaminodiphenylmethane 3.087505956
MESH:D002779 Cholestasis 4,4'-diaminodiphenylmethane 3.5119486331 9022650
MESH:D015179 Colorectal Neoplasms Azacitidine 2.7319934284
MESH:D019465 Craniofacial Abnormalities marker/mechanism 16402211
MESH:D017449 Dermatitis, Allergic Contact 4,4'-diaminodiphenylmethane 3.558970840 8156756 11298694 14531868 11906362 2524372 12868966 18759878
MESH:D003877 Dermatitis, Contact 4,4'-diaminodiphenylmethane 4.103621924 2952479
MESH:D056486 Drug-Induced Liver Injury 4,4'-diaminodiphenylmethane 2.0616192314 6679447 7440962 9653073 9328219 9022650 1440618 6482804 18692083 18648102 11289319 18289764 8291058
MESH:C535606 Duane-radial ray syndrome marker/mechanism
MESH:D004370 Duane Retraction Syndrome marker/mechanism 16402211
MESH:D004938 Esophageal Neoplasms 4,4'-diaminodiphenylmethane 2.193581430
MESH:D005350 Fibroma 4,4'-diaminodiphenylmethane 6.096705139
MESH:D006042 Goiter 4,4'-diaminodiphenylmethane 4.647505956
MESH:D006505 Hepatitis 4,4'-diaminodiphenylmethane 4.196705139
MESH:D006965 Hyperplasia 4,4'-diaminodiphenylmethane 4.7015034207
OMIM:147750 IVIC SYNDROME marker/mechanism
MESH:D007565 Jaundice 4,4'-diaminodiphenylmethane 6.098074119 9022650
MESH:D007680 Kidney Neoplasms 4,4'-diaminodiphenylmethane 3.406582329
MESH:D007938 Leukemia Azacitidine 3.8919148494
MESH:D007951 Leukemia, Myeloid Azacitidine 5.1719077051
MESH:D015470 Leukemia, Myeloid, Acute Azacitidine 3.0617596541 18720364
MESH:D054429 Leukemia, Myelomonocytic, Juvenile Azacitidine 5.8019299654
MESH:D008105 Liver Cirrhosis, Biliary 4,4'-diaminodiphenylmethane 3.4715034207 9327722
MESH:D008114 Liver Neoplasms, Experimental 4,4'-diaminodiphenylmethane 2.80598648 3712494 1399818 6587162
MESH:D008175 Lung Neoplasms Azacitidine 2.7321224363
MESH:D009006 Monosomy Azacitidine 7.1519299654
MESH:D009101 Multiple Myeloma Azacitidine 4.3119549372 18443271
MESH:D009190 Myelodysplastic Syndromes Azacitidine 4.2417611569 19805378 17596541 18720364
MESH:D009362 Neoplasm Metastasis 4,4'-diaminodiphenylmethane 2.623581430
MESH:D009436 Neural Tube Defects 4,4'-diaminodiphenylmethane 3.216679447
MESH:D009784 Occupational Diseases 4,4'-diaminodiphenylmethane 3.924026338 6482804
MESH:D009902 Optic Neuritis 4,4'-diaminodiphenylmethane 6.093988306
MESH:D010212 Papilloma 4,4'-diaminodiphenylmethane 4.247296757
MESH:D010787 Photosensitivity Disorders 4,4'-diaminodiphenylmethane 5.546228378
MESH:D011471 Prostatic Neoplasms Azacitidine 4.0618324645
MESH:D012162 Retinal Degeneration 4,4'-diaminodiphenylmethane 3.743692021
MESH:D013964 Thyroid Neoplasms 4,4'-diaminodiphenylmethane 3.267505956 1399818 6582329 6587162 3712494
MESH:D001749 Urinary Bladder Neoplasms 4,4'-diaminodiphenylmethane 2.428074119
No data
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Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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